Saccharomyces cerevisiae -
Functional Catalogue

mips


 

transcriptional control (333 ORFs)

YOR259c     RPT4     26S proteasome regulatory subunit
YHR193c     EGD2     alpha subunit of the nascent polypeptide-associated complex
YDR252w     BTT1     alternate beta subunit of the nascent polypeptide-associated complex
YDL197c     ASF2     anti-silencing protein
YJL115w     ASF1     anti-silencing protein
YDR173c     ARG82    arginine metabolism transcription factor
YKL112w     ABF1     ARS-binding factor
YFL028c     CAF16    ATP-binding cassette transporter family member
YDR123c     INO2     basic helix-loop-helix (BHLH) transcription factor
YOL108c     INO4     basic helix-loop-helix transcription factor
YOR344c     TYE7     basic helix-loop-helix transcription factor
YOL067c     RTG1     basic helix-loop-helix transcription factor that regulates CIT2 gene expression
YBL103c     RTG3     bHLH/zip transcription factor that regulates CIT2 gene expression
YGL209w     MIG2     C2H2 zinc-finger protein
YLR433c     CNA1     calcineurin B, catalytic subunit
YML057w     CMP2     calcineurin B, catalytic subunit
YKL190w     CNB1     calcineurin B, regulatory subunit
YNL027w     CRZ1     calcineurin responsive zinc-finger
YIL033c     BCY1     cAMP dependent protein kinase, regulatory subunit
YJL164c     TPK1     cAMP-dependent protein kinase 1, catalytic chain
YPL203w     TPK2     cAMP-dependent protein kinase 2, catalytic chain
YKL166c     TPK3     cAMP-dependent protein kinase 3, catalytic chain
YKL139w     CTK1     carboxy-terminal domain (CTD) kinase, alpha subunit
YJL006c     CTK2     carboxy-terminal domain (CTD) kinase, beta subunit
YML112w     CTK3     carboxy-terminal domain (CTD) kinase, gamma subunit
YBL021c     HAP3     CCAAT-binding factor subunit
YGL237c     HAP2     CCAAT-binding factor subunit
YKL109w     HAP4     CCAAT-binding factor subunit
YOR358w     HAP5     CCAAT-binding factor subunit
YJR122w     CAF17    CCR4 associated factor
YKR036c     CAF4     CCR4 associated factor
YBR215w     HPC2     cell cycle regulatory protein
YDL220c     CDC13    cell division control protein
YMR061w     RNA14    component of pre-mRNA 3'-end processing factor CF I
YNR023w     SNF12    component of SWI/SNF global transcription activator complex
YOR290c     SNF2     component of SWI/SNF global transcription activator complex
YPL016w     SWI1     component of SWI/SNF global transcription activator complex
YBR289w     SNF5     component of SWI/SNF transcription activator complex
YDR073w     SNF11    component of SWI/SNF transcription activator complex
YCR042c     TSM1     component of TFIID complex
YHR099w     TRA1     component of the Ada-Spt transcriptional regulatory complex
YPR072w     NOT5     component of the NOT protein complex
YLR192c     HCR1     component of translation initiation factor eIF3, has similarity to human eIF3 p35 subunit
YGL166w     CUP2     copper-dependent transcription factor
YNL167c     SKO1     cre-binding bzip protein
YOL001w     PHO80    cyclin
YPL042c     SSN3     cyclin-dependent CTD kinase
YPL031c     PHO85    cyclin-dependent protein kinase
YDR334w     SWR1     DEAH-box protein, putative RNA helicase
YNL186w     UBP10    derepression of telomeric silencing
YLR226w     BUR2     divergent CDK-cyclin complex
YDR217c     RAD9     DNA repair checkpoint protein
YNL216w     RAP1     DNA-binding protein with repressor and activator activity
YLR418c     CDC73    DNA-directed RNA polymerase II accessory protein
YBR279w     PAF1     DNA-directed RNA polymerase II regulator
YGL208w     SIP2     dominant suppressor of some ts mutations in RPO21 and PRP4
YOR047c     STD1     dosage-dependent modulator of glucose repression
YHR154w     ESC4     Establishes Silent Chromatin
YIL131c     FKH1     forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle
YER159c     BUR6     functional homolog of human NC2alpha
YDR397c     NCB2     functional homolog of human NC2beta/Dr1
YPL037c     EGD1     GAL4 DNA-binding enhancer protein
YBR020w     GAL1     galactokinase
YDR009w     GAL3     galactokinase
YIL038c     NOT3     general negative regulator of transcription, subunit 3
YBR112c     CYC8     general repressor of transcription
YCR084c     TUP1     general transcription repressor
YDR176w     NGG1     general transcriptional adaptor or co-activator
YDR392w     SPT3     general transcriptional adaptor or co-activator
YDR448w     ADA2     general transcriptional adaptor or co-activator
YBR045c     GIP1     GLC7-interacting protein
YNL236w     SIN4     global regulator protein
YHL025w     SNF6     global transcription activator
YER027c     GAL83    glucose repression protein
YNL199c     GCR2     glycolytic genes transcriptional activator
YGL073w     HSF1     heat shock transcription factor
YPR065w     ROX1     heme-dependent transcriptional repressor of hypoxic genes
YDR006c     SOK1     high copy suppressor of a cyclic AMP-dependent protein kinase mutant
YJR147w     HMS2     High-copy MEP2 Suppressor
YMR070w     MOT3     high-copy suppressor of MOT1-SPT3 synthetic lethality
YGR252w     GCN5     histone acetyltransferase
YNL021w     HDA1     histone deacetylase A
YNL330c     RPD3     histone deacetylase B
YDR225w     HTA1     histone H2A
YBL003c     HTA2     histone H2A.2
YDR224c     HTB1     histone H2B
YBL002w     HTB2     histone H2B.2
YBR010w     HHT1     histone H3
YNL031c     HHT2     histone H3
YBR009c     HHF1     histone H4
YNL030w     HHF2     histone H4
YBL008w     HIR1     histone transcription regulator
YOR038c     HIR2     histone transcription regulator
YDL106c     PHO2     homeodomain protein
YOL055c     THI20    hydroxymethylpyrimidine phosphate (HMP-P) kinase
YDR138w     HPR1     hyperrecombination protein related to TOP1P
YKL159c     RCN1     inhibitor of calcineurin
YJL089w     SIP4     interacts with SNF1 protein kinase
YKL032c     IXR1     intrastrand crosslink recognition protein and transcription factor
YBR081c     SPT7     involved in alteration of transcription start site selection
YJR140c     HIR3     involved in cell cycle regulation of histone transcription
YKR072c     SIS2     involved in cell cycle-specific gene expression
YPL177c     CUP9     involved in copper homeostasis repression of protein import
YER088c     DOT6     involved in derepression of telomeric silencing
YIL010w     DOT5     involved in derepression of telomeric silencing
YIL128w     MET18    involved in NER repair and RNA polymerase II transcription
YDR439w     LRS4     involved in rDNA silencing
YNL251c     NRD1     involved in regulation of nuclear pre-mRNA abundance
YIL046w     MET30    involved in regulation of sulfur assimilation genes and cell cycle progression
YDL153c     SAS10    involved in silencing
YDR363w     ESC2     involved in silencing
YMR127c     SAS2     involved in silencing at HMR
YGR097w     ASK10    involved in SKN7P-dependent transcription
YIR018w     YAP5     involved in transcription activation
YOL028c     YAP7     involved in transcription activation
YLR039c     RIC1     involved in transcription of ribosomal proteins and ribosomal RNA
YNL097c     PHO23    involved in transcriptional regulation of PHO5
YGL071w     RCS1     iron-regulated transcriptional repressor
YJR060w     CBF1     kinetochore protein
YDR159w     SAC3     leucine permease transcriptional regulator
YGR100w     MDR1     MAC1P interacting protein
YBR182c     SMP1     MADS-box transcription factor
YBR297w     MAL33    maltose fermentation regulatory protein
YGR288w     MAL13    maltose pathway regulatory protein
YCR039c     MATALPHA2  mating type regulatory protein, expressed copy at MAT locus
YCR040w     MATALPHA1  mating type regulatory protein, expressed copy at MAT locus
YCL066w     HMLALPHA1  mating type regulatory protein, silenced copy at HML
YGL025c     PGD1     mediator complex subunit
YHL027w     RIM101   meiotic regulatory protein
YOL135c     MED7     member of RNA Polymerase II transcriptional regulation mediator complex
YJR032w     CPR7     member of the cyclophilin family
YLR216c     CPR6     member of the cyclophilin family
YHR211w     FLO5     member of the FLO1P family of flocculation proteins
YDR191w     HST4     member of the SIR2P family of putative NAD-dependent histone deacetylases
YOL148c     SPT20    member of the TBP class of SPT proteins that alter transcription site selection
YMR021c     MAC1     metal binding activator
YJL056c     ZAP1     metalloregulatory protein involved in zinc-responsive transcriptional regulation
YLR131c     ACE2     metallothionein expression activator
YBR026c     (MRF1)   mitochondrial respiratory function protein
YER161c     SPT2     multifunctional HMG-like chromatin protein
YOR298c-a   MBF1     multiprotein bridging factor mediates GCN4-dependent transcriptional activation
YML051w     GAL80    negative regulator for expression of galactose-induced genes
YKL185w     ASH1     negative regulator of HO transcription
YPL139c     UME1     negative regulator of meiosis
YHL020c     OPI1     negative regulator of phospholipid biosynthesis pathway
YDR464w     SPP41    negative regulator of PRP3 and PRP4 gene expression
YGL151w     NUT1     negative transcription regulator from artifical reporters
YPR168w     NUT2     negative transcription regulator from artifical reporters
YDR207c     UME6     negative transcriptional regulator
YGL221c     NIF3     NGG1P-interacting factor 3
YCR093w     CDC39    nuclear protein
YGL115w     SNF4     nuclear regulatory protein
YML065w     ORC1     origin recognition complex, 104 KD subunit
YHR118c     ORC6     origin recognition complex, 50 KD subunit
YNL261w     ORC5     origin recognition complex, 50 kDa subunit
YPR162c     ORC4     origin recognition complex, 56 KD subunit
YLL004w     ORC3     origin recognition complex, 62 kDa subunit
YBR060c     ORC2     origin recognition complex, 72 kDa subunit
YAL051w     OAF1     peroxisome proliferating transcription factor
YOR363c     PIP2     peroxisome proliferating transcription factor
YBL005w     PDR3     pleiotropic drug resistance regulatory protein
YNL076w     MKS1     pleiotropic regulatory factor
YKL015w     PUT3     positive activator of the proline utilisation pathway
YDL080c     THI3     positive regulation factor of thiamin metabolism
YGL192w     IME4     positive transcription factor for IME2
YDR421w     ARO80    positive transcription regulator of ARO9 and ARO10
YDR017c     KCS1     potential transcription factor of the BZIP type
YDR463w     STP1     pre-tRNA splicing protein, transcription factor
YBL066c     SEF1     putative transcription factor
YBR275c     RIF1     RAP1-interacting factor 1
YFR029w     PTR3     regulator of expression of the PTR2, GAP1 and BAP2 genes
YKL038w     RGT1     regulator of glucose-induced genes
YBR240c     THI2     regulator of the thiamine biosynthetic genes
YDR257c     RMS1     regulatory protein
YMR016c     SOK2     regulatory protein in the PKA signal transduction pathway
YDR213w     UPC2     regulatory protein involved in control of sterol uptake
YCL055w     KAR4     regulatory protein required for pheromone induction of karyogamy genes
YLR176c     RFX1     repressor of DNA damage-inducible genes
YIL106w     MOB1     required for completion of mitosis and maintenance of ploidy
YER109c     FLO8     required for diploid filamentous growth
YNR052c     POP2     required for glucose derepression
YER120w     SCS2     required for inositol metabolism
YMR179w     SPT21    required for normal transcription at a number of loci
YKL093w     MBR1     required for optimal growth on glycerol
YCL054w     SPB1     required for ribosome synthesis, putative methylase
YHR058c     MED6     RNA polymerase II transcriptional regulation mediator
YMR139w     RIM11    ser/thr protein kinase
YGR092w     DBF2     ser/thr protein kinase related to DBF20P
YBL052c     SAS3     silencing protein
YOL068c     HST1     silencing protein
YOR025w     HST3     silencing protein
YDR227w     SIR4     silencing regulatory and DNA-repair protein
YLR442c     SIR3     silencing regulatory and DNA-repair protein
YKR101w     SIR1     silencing regulatory protein
YDL042c     SIR2     silencing regulatory protein and DNA-repair protein
YKL070w              similarity to B.subtilis transcriptional regulatory protein
YDL070w     BDF2     similarity to bromodomain protein BDF1P
YBR061c              similarity to E.coli ftsJ protein
YGR249w     MGA1     similarity to heat shock transcription factors
YPL015c     HST2     similarity to HST1P and SIR2P
YNL107w     YAF9     similarity to human AF-9 protein
YAR003w     FUN16    similarity to human RB protein binding protein
YER169w     RPH1     similarity to human retinoblastoma binding protein 2
YJR119c              similarity to human retinoblastoma binding protein 2
YOL133w     HRT1     similarity to Lotus RING-finger protein
YER130c              similarity to MSN2P and weak similarity to MSN4P
YER184c              similarity to multidrug resistance proteins PDR3P and PDR1P
YPR115w              similarity to probable transcription factor ASK10P, and to YNL047c and YIL105c
YIL130w              similarity to PUT3P and to hypothetical protein YJL206c
YCR020c     PET18    similarity to regulatory protein
YGL150c     INO80    similarity to SNF2P and human SNF2alpha
YCR106w              similarity to transcription factor
YLL054c              similarity to transcription factor PIP2P
YDR303c     RSC3     similarity to transcriptional regulator proteins
YJL103c              similarity to YBR239c
YJL206c              similarity to YIL130p and PUT3P
YHR178w     STB5     SIN3 binding protein
YKL072w     STB6     SIN3 binding protein
YDR169c     STB3     SIN3 protein-binding protein
YMR053c     STB2     SIN3P binding protein
YNL309w     STB1     SIN3P binding protein
YBR103w     SIF2     SIR4P interacting protein
YLR399c     BDF1     sporulation protein
YNL204c     SPS18    sporulation-specific zinc-finger protein
YMR037c     MSN2     stress responsive regulatory protein
YIL101c     XBP1     stress-induced transcriptional repressor
YBR245c     ISW1     strong similarity to D.melanogaster iswi protein
YDR026c              strong similarity to DNA-binding protein REB1P
YOR304w     ISW2     strong similarity to Drosophila ISW1 and human SNF2P homolog
YGL236c     MTO1     strong similarity to gidA E.coli protein
YFL052w              strong similarity to Mal63p, YPR196w and MAL13P
YPR196w              strong similarity to regulatory protein Mal63p
YLR228c     ECM22    strong similarity to YDR213w, weak similarity to LYS14P
YHR056c     RSC30    strong similarity to YHR054c
YML081w              strong similarity to ZMS1 protein
YGL133w     ITC1     subunit of ISW2 chromatin remodelling complex
YMR263w     SAP30    subunit of the histone deacetylase B complex
YEL056w     HAT2     subunit of the major yeast histone acetyltransferase
YCR052w     RSC6     subunit of the RSC complex
YFR037c     RSC8     subunit of the RSC complex
YIL126w     STH1     subunit of the RSC complex
YLR321c     SFH1     subunit of the RSC complex
YOR213c     SAS5     subunit of the RSC complex
YGL254w     FZF1     sulfite resistance protein
YNL222w     SSU72    suppressor of cs mutant of SUA7
YDR310c     SUM1     suppressor of SIR mutations
YBR198c     TAF90    TFIID and SAGA subunit
YDR145w     TAF61    TFIID and SAGA subunit
YDR167w     TAF25    TFIID and SAGA subunit
YGL112c     TAF60    TFIID and SAGA subunit
YBL093c     ROX3     transcription factor
YBR049c     REB1     transcription factor
YCR065w     HCM1     transcription factor
YDL165w     CDC36    transcription factor
YDR146c     SWI5     transcription factor
YER111c     SWI4     transcription factor
YFL031w     HAC1     transcription factor
YFR034c     PHO4     transcription factor
YGL013c     PDR1     transcription factor
YKL043w     PHD1     transcription factor
YKR099w     BAS1     transcription factor
YLR098c     CHA4     transcription factor
YLR182w     SWI6     transcription factor
YLR256w     HAP1     transcription factor
YLR451w     LEU3     transcription factor
YOR140w     SFL1     transcription factor
YPL248c     GAL4     transcription factor
YFL021w     GAT1     transcription factor for nitrogen regulation
YER040w     GLN3     transcription factor for positive nitrogen regulation
YML099c     ARG81    transcription factor involved in arginine metabolism
YMR042w     ARG80    transcription factor involved in arginine metabolism
YMR280c     CAT8     transcription factor involved in gluconeogenesis
YGL181w     GTS1     transcription factor of the GCS1P/GLO3P/SPS18P family
YMR043w     MCM1     transcription factor of the MADS box family
YPL089c     RLM1     transcription factor of the MADS box family
YLR014c     PPR1     transcription factor regulating pyrimidine pathway
YJR094c     IME1     transcription factor required for sporulation
YHR206w     SKN7     transcription factor with similarity to HSF1P
YDR259c     YAP6     transcription factor, of a fungal-specific family of bzip proteins
YHL009c     YAP3     transcription factor, of a fungal-specific family of bzip proteins
YDL056w     MBP1     transcription factor, subunit of the MBF factor
YJL127c     SPT10    transcription regulatory protein
YJL176c     SWI3     transcription regulatory protein
YOL004w     SIN3     transcription regulatory protein
YPL082c     MOT1     transcriptional accessory protein
YDR423c     CAD1     transcriptional activator
YHR084w     STE12    transcriptional activator
YKL062w     MSN4     transcriptional activator
YOL116w     MSN1     transcriptional activator
YOR028c     CIN5     transcriptional activator
YPL075w     GCR1     transcriptional activator
YIR023w     DAL81    transcriptional activator for allantoin and GABA catabolic genes
YNL314w     DAL82    transcriptional activator for allantoin catabolic genes
YDL170w     UGA3     transcriptional activator for GABA catabolic genes
YML007w     YAP1     transcriptional activator involved in oxidative stress response
YEL009c     GCN4     transcriptional activator of amino acid biosynthetic genes
YOL089c     HAL9     transcriptional activator of ENA1
YDR034c     LYS14    transcriptional activator of lysine pathway genes
YIL129c     TAO3     Transcriptional Activator of OCH1
YIR017c     MET28    transcriptional activator of sulfur amino acid metabolism
YNL103w     MET4     transcriptional activator of sulfur metabolism
YPR104c     FHL1     transcriptional activator of the forkhead/hnf3 family
YLR055c     SPT8     transcriptional adaptor or co-activator
YMR039c     SUB1     transcriptional coactivator
YPL254w     HFI1     transcriptional coactivator
YAL021c     CCR4     transcriptional regulator
YER164w     CHD1     transcriptional regulator
YIL084c     SDS3     transcriptional regulator
YNL012w     SPO1     transcriptional regulator involved in sporulation
YDR160w     SSY1     transcriptional regulator of several transporter genes
YDR253c     MET32    transcriptional regulator of sulfur amino acid metabolism
YPL038w     MET31    transcriptional regulator of sulfur amino acid metabolism
YER068w     MOT2     transcriptional repressor
YGL035c     MIG1     transcriptional repressor
YJL110c     GZF3     transcriptional repressor
YKR034w     DAL80    transcriptional repressor for allantoin and GABA catabolic genes
YDR043c     NRG1     transcriptional repressor for glucose repression of STA1 gene expression
YMR182c     RGM1     transcriptional repressor protein
YBR083w     TEC1     Ty transcription activator
YOR337w     TEA1     TY1 enhancer activator
YER151c     UBP3     ubiquitin-specific proteinase
YLR013w     GAT3     weak similarity to nitrogen regulatory proteins
YLR278c              weak similarity to regulatory proteins
YML076c              weak similarity to transcription factor
YBR033w              weak similarity to transcription factors
YKR064w              weak similarity to transcription factors
YLR266c              weak similarity to transcription factors
YKL222c              weak similarity to transcription factors, similarity to finger proteins YOR162c, YOR172w and YLR266c
YBL054w              weak similarity to transforming protein (B-myb)
YMR019w     STB4     weak similarity to YIL130w, PUT3P and other transcription factors
YER122c     GLO3     zinc finger protein
YDR216w     ADR1     zinc-finger transcription factor
YGR044c     RME1     zinc-finger transcription factor

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