Saccharomyces cerevisiae -
Functional Catalogue

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DNA repair (88 ORFs)

YKL145w     RPT1     26S proteasome regulatory subunit
YER142c     MAG1     3-methyladenine DNA glycosylase
YML060w     OGG1     8-oxoguanine DNA glycosylase
YKL114c     APN1     AP endonuclease
YBL019w     APN2     AP endonuclease, exonuclease III homolog
YJL092w     HPR5     ATP-dependent DNA helicase
YPL204w     HRR25    casein kinase I, ser/thr/tyr protein kinase
YMR106c     YKU80    component of DNA end-joining repair pathway
YPR056w     TFB4     component of RNA polymerase transcription initiation TFIIH factor
YPL022w     RAD1     component of the nucleotide excision repairosome
YDL108w     KIN28    cyclin-dependent ser/thr protein kinase
YOR386w     PHR1     deoxyribodipyrimidine photo-lyase
YOR368w     RAD17    DNA damage checkpoint control protein
YPL194w     DDC1     DNA damage checkpoint protein
YDR096w     GIS1     DNA damage-responsive repressor of PHR1
YER176w     ECM32    DNA dependent ATPase/DNA helicase B
YIL143c     SSL2     DNA helicase
YLR032w     RAD5     DNA helicase
YML061c     PIF1     DNA helicase involved in mitochondrial DNA repair and telomere length
YER171w     RAD3     DNA helicase/ATPase
YDL164c     CDC9     DNA ligase
YOR005c     DNL4     DNA ligase IV
YGL090w     LIF1     DNA ligase IV interacting factor
YIL139c     REV7     DNA polymerase zeta subunit
YMR224c     MRE11    DNA repair and meiotic recombination protein
YAL015c     NTG1     DNA repair protein
YCR066w     RAD18    DNA repair protein
YDR004w     RAD57    DNA repair protein
YDR076w     RAD55    DNA repair protein
YDR369c     XRS2     DNA repair protein
YDR419w     RAD30    DNA repair protein
YEL019c     MMS21    DNA repair protein
YER095w     RAD51    DNA repair protein
YML095c     RAD10    DNA repair protein
YMR137c     PSO2     DNA repair protein
YNL250w     RAD50    DNA repair protein
YOR346w     REV1     DNA repair protein
YGL163c     RAD54    DNA-dependent ATPase of the SNF2P family
YJR006w     HYS2     DNA-directed DNA polymerase delta, 55 KD subunit
YDL102w     CDC2     DNA-directed DNA polymerase delta, catalytic 125 KD subunit
YFR023w     PES4     DNA-directed DNA polymerase epsilon suppressor
YNL262w     POL2     DNA-directed DNA polymerase epsilon, catalytic subunit A
YPL167c     REV3     DNA-directed DNA polymerase zeta subunit
YGL058w     RAD6     E2 ubiquitin-conjugating enzyme
YKR056w     RNC1     endo-exonuclease
YOL043c     NTG2     endonuclease III-like glycosylase 2
YER162c     RAD4     excision repair protein
YLR288c     MEC3     G2-specific checkpoint protein
YFL014w     HSP12    heat shock protein
YMR284w     YKU70    high-affinity DNA-binding protein
YML058w-a   HUG1     hydroxyurea and UV and gamma radiation induced
YPL164c     MLH3     insertion and deletion mismatch repair protein
YIL128w     MET18    involved in NER repair and RNA polymerase II transcription
YDR386w     MUS81    involved in the repair of UV and methylation induced DNA damage
YGR144w     THI4     involved in thiamine biosynthesis and DNA repair
YMR035w     IMP2     mitochondrial inner membrane protease subunit
YKR095w     MLP1     myosin-like protein related to USO1P
YBR114w     RAD16    nucleotide excision repair protein
YJR052w     RAD7     nucleotide excision repair protein
YMR201c     RAD14    nucleotide excision repair protein
YEL037c     RAD23    nucleotide excision repair protein (ubiquitin-like protein)
YDL200c     MGT1     O6-methylguanine DNA repair methyltransferase
YGL087c     MMS2     part of the error-free postreplication repair pathway
YJR043c     POL32    polymerase-associated gene, third (55 kDa) subunit of DNA polymerase delta
YIR002c     MPH1     protection of the genome from spontaneous and chemically induced damage
YDL101c     DUN1     protein kinase
YBR098w     MMS4     putative transcriptional (co)activator for DNA damage
YML032c     RAD52    recombination and DNA repair protein
YBR073w     RDH54    required for mitotic diploid-specific recombination and repair and meiosis
YGR180c     RNR4     ribonucleotide reductase small subunit
YIL066c     RNR3     ribonucleotide reductase, repair inducible large subunit
YPL153c     RAD53    ser/thr/tyr protein kinase
YDR227w     SIR4     silencing regulatory and DNA-repair protein
YLR442c     SIR3     silencing regulatory and DNA-repair protein
YDL042c     SIR2     silencing regulatory protein and DNA-repair protein
YDR061w              similarity to E.coli modF and photorepair protein phrA
YAL019w     FUN30    similarity to helicases of the SNF2/RAD54 family
YLR035c     MLH2     similarity to human mutL protein homolog, mouse PMS2, MLH1P and PMS1P
YKL113c     RAD27    ssDNA endonuclease and 5'-3'exonuclease
YIL153w     RRD1     strong similarity to human phosphotyrosyl phosphatase activator
YFR038w              strong similarity to mouse lymphocyte specific helicase
YGR258c     RAD2     structure-specific nuclease of the nucleotide excision repairosome
YDL088c     ASM4     suppressor of temperature-sensitive mutations in Pol3p
YDR311w     TFB1     TFIIH subunit (transcription initiation factor), 75 kD
YPR025c     CCL1     TFIIH subunit (transcription initiation factor), cyclin C component
YLR005w     SSL1     TFIIH subunit (transcription initiation factor), factor B
YDR460w     TFB3     TFIIH subunit (transcription/repair factor)
YPL122c     TFB2     TFIIH subunit (transcription/repair factor)

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