PF00106	short chain dehydrogenase
2.1468	SUB158	>= 3 any ring size 5
1.4054	SUB360	C(~C)(:N)(:N)
1.1143	SUB389	C(:C)(:N)(:N)
0.7664	SUB712	C-C(C)(C)-C-C
0.6095	SUB335	C(~C)(~C)(~C)(~C)
0.6051	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.2556	SUB407	O(~C)(~H)
0.2514	SUB261	>= 3 hetero-aromatic rings
0.2213	SUB309	O-H
0.2154	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.2084	SUB3	>= 16 H
0.1848	SUB13	>= 16 C
0.1715	SUB602	N-C:C:C-N
0.1490	SUB668	C=C-C-O-[#1]
0.1038	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0953	SUB580	O=C-C-C-C
0.0065	SUB622	N-C:C:C:N
PF00255	Glutathione peroxidase
2.1118	SUB414	S(~C)(~H)
0.5932	SUB695	O=C-C-C-C-C=O
PF01126	Heme oxygenase
1.9413	SUB158	>= 3 any ring size 5
PF01094	Receptor family ligand binding region
1.8035	SUB686	O=C-C-C-C-N
0.7340	SUB718	Cc1ccc(Cl)cc1
0.6657	SUB691	O-C-C-C-C-C-O
0.4269	SUB288	C-F
0.4042	SUB21	>= 4 O
0.3298	SUB781	CC1CCC(Cl)CC1
0.2866	SUB15	>= 1 N
0.0518	SUB24	>= 1 F
PF03171	2OG-Fe(II),  oxygenase superfamily
1.7707	SUB687	O=C-C-C-C-O
0.4657	SUB580	O=C-C-C-C
0.1473	SUB381	C(~O)(~O)
PF03414	Glycosyltransferase family 6
1.7514	SUB348	C(~C)(~H)(~O)(~O)
0.2422	SUB664	O-C-C-O-[#1]
0.2031	SUB682	O-C-C-C-C-O
PF00042	Globin
1.6343	SUB387	C(:C)(:C)(:N)
0.2773	SUB259	>= 2 hetero-aromatic rings
0.2697	SUB700	O-C-C-C-C-C(C)-C
0.1429	SUB578	C:C-N-C:C
0.1093	SUB358	C(~C)(:C)(:N)
0.0048	SUB540	N=C-C-[#1]
PF00167	Fibroblast growth factor
1.6299	SUB409	O(~H)(~S)
0.3958	SUB572	[#1]-C-O-[#1]
0.2182	SUB34	>= 1 S
0.0602	SUB368	C(~H)(~O)(~O)
PF00348	Polyprenyl synthetase
1.5807	SUB32	>= 2 P
PF00464	Serine hydroxymethyltransferase
1.5797	SUB567	O-C-C-N
0.9029	SUB686	O=C-C-C-C-N
0.6826	SUB554	O=C-C=C
0.1220	SUB624	O=C-C:C-C
0.0474	SUB598	O=C-C-C:C
0.0031	SUB494	O=C-C:C
PF00102	Protein-tyrosine phosphatase
1.5105	SUB309	O-H
0.5749	SUB668	C=C-C-O-[#1]
0.3562	SUB293	C-P
0.3077	SUB593	N-C-C-C-C
0.2664	SUB537	O=C-C-N
0.0443	SUB463	O-C-C=O
0.0276	SUB538	O=C-C-O
0.0089	SUB21	>= 4 O
PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
1.5065	SUB433	C(-C)(-C)(=O)
0.5812	SUB17	>= 4 N
0.5771	SUB602	N-C:C:C-N
0.3791	SUB499	O-C=C-C
0.3647	SUB151	>= 2 any ring size 5
0.3055	SUB22	>= 8 O
0.0861	SUB674	O=C-C=C-N
0.0508	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.0389	SUB668	C=C-C-O-[#1]
0.0093	SUB736	Cc1cc(O)ccc1
0.0029	SUB594	N-C-C-C-N
PF00107	Zinc-binding dehydrogenase
1.5033	SUB449	C(-H)(=O)
0.6653	SUB421	C=O
0.2745	SUB446	C(-H)(-N)(=C)
0.1559	SUB10	>= 2 C
0.1226	SUB284	C-H
0.1122	SUB622	N-C:C:C:N
0.0789	SUB673	O=C-C=C-[#1]
0.0178	SUB452	C(-N)(=O)
PF00551	Formyl transferase
1.4956	SUB695	O=C-C-C-C-C=O
0.3363	SUB691	O-C-C-C-C-C-O
0.0696	SUB647	O=C-N-C-[#1]
PF07884	Vitamin K epoxide reductase family
1.4784	SUB433	C(-C)(-C)(=O)
0.2129	SUB598	O=C-C-C:C
0.0034	SUB624	O=C-C:C-C
PF00079	Serpin (serine protease inhibitor), 
1.4255	SUB706	O=C-C-C-C-C(O)-C
0.5100	SUB407	O(~C)(~H)
0.3031	SUB682	O-C-C-C-C-O
0.2873	SUB615	C-C-O-C-C
0.2855	SUB713	C-C(C)-C(C)-C
0.2564	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.2177	SUB440	C(-C)(-N)(=O)
0.1071	SUB646	O=C-N-C-C
0.1006	SUB783	OC1CCC(O)CC1
0.0532	SUB618	C-C-C-O-[#1]
0.0025	SUB693	O=C-C-C-C-C-C
PF00324	Amino acid permease
1.4095	SUB484	N-S-C:C
1.0195	SUB38	>= 1 Cl
0.7753	SUB441	C(-C)(-O)(=O)
0.4607	SUB529	[#1]-N-C-[#1]
0.4477	SUB453	C(-O)(=O)
0.2668	SUB42	>= 1 K
0.2221	SUB567	O-C-C-N
0.1953	SUB644	[#1]-C-C-N-[#1]
0.1122	SUB694	O=C-C-C-C-C-O
0.0785	SUB16	>= 2 N
0.0565	SUB738	Cc1cc(N)ccc1
PF00061	Lipocalin / cytosolic fatty-acid binding protein family
1.4062	SUB13	>= 16 C
0.8003	SUB757	Cc1c(O)cccc1
0.4085	SUB545	O-C:C-O
0.3463	SUB465	N-C-C=C
0.2783	SUB643	O-C-C-C=O
0.2286	SUB407	O(~C)(~H)
0.2169	SUB499	O-C=C-C
0.1481	SUB582	O=C-C-C-O
0.1407	SUB543	O-C:C-[#1]
0.1395	SUB583	C-C-C-C-C
0.1062	SUB762	Oc1c(O)cccc1
0.0966	SUB381	C(~O)(~O)
0.0932	SUB525	C-C=C-C
0.0756	SUB517	[#1]-C=C-[#1]
0.0407	SUB620	O-C-C=C-C
0.0084	SUB503	N-C=C-[#1]
PF00168	C2 domain
1.3993	SUB799	CC1CC(O)CCC1
0.0934	SUB582	O=C-C-C-O
0.0578	SUB249	>= 1 any ring size 10
0.0155	SUB643	O-C-C-C=O
0.0010	SUB406	O(~C)(~C)
PF00625	Guanylate kinase
1.3972	SUB4	>= 32 H
0.3997	SUB430	C(#N)(-C)
0.1322	SUB20	>= 2 O
0.0415	SUB677	N#C-C-C-C
PF00155	Aminotransferase class I and II
1.3830	SUB567	O-C-C-N
1.1558	SUB498	O-C:C:N
0.8254	SUB588	N-C:C-O-[#1]
0.5323	SUB686	O=C-C-C-C-N
0.4270	SUB537	O=C-C-N
0.3633	SUB529	[#1]-N-C-[#1]
0.2944	SUB341	C(~C)(~C)(~N)
0.2629	SUB339	C(~C)(~C)(~H)(~N)
0.2576	SUB462	O-C-C=N
PF00850	Histone deacetylase domain
1.3827	SUB302	N-O
0.8007	SUB396	N(~C)(~O)
PF00017	SH2 domain
1.3778	SUB714	Cc1ccc(C)cc1
1.1965	SUB360	C(~C)(:N)(:N)
0.7535	SUB494	O=C-C:C
0.7146	SUB259	>= 2 hetero-aromatic rings
0.6464	SUB568	O-C-C-O
0.5587	SUB715	Cc1ccc(O)cc1
0.4931	SUB261	>= 3 hetero-aromatic rings
0.4539	SUB426	P=O
0.3573	SUB602	N-C:C:C-N
0.3020	SUB759	Cc1c(N)cccc1
0.2824	SUB457	P(-O)(=O)
0.1771	SUB339	C(~C)(~C)(~H)(~N)
0.1712	SUB682	O-C-C-C-C-O
0.0996	SUB412	P(~O)(~O)
0.0768	SUB31	>= 1 P
0.0717	SUB193	>= 3 any ring size 6
0.0265	SUB622	N-C:C:C:N
0.0159	SUB522	C:N-C-[#1]
0.0151	SUB315	O-P
0.0110	SUB531	N:C-C:C
PF00069	Protein kinase domain
1.3738	SUB217	>= 1 saturated or aromatic heteroatom-containing ring size 7
1.0116	SUB31	>= 1 P
0.9721	SUB503	N-C=C-[#1]
0.9160	SUB140	>= 2 saturated or aromatic heteroatom-containing ring size 4
0.7710	SUB365	C(~F)(:C)
0.7689	SUB602	N-C:C:C-N
0.6915	SUB760	Cc1c(Cl)cccc1
0.5710	SUB591	C-C:C-O-[#1]
0.5598	SUB216	>= 1 saturated or aromatic nitrogen-containing ring size 7
0.5585	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.5534	SUB672	O=C-C=C-C
0.5161	SUB151	>= 2 any ring size 5
0.4694	SUB622	N-C:C:C:N
0.4686	SUB367	C(~H)(~O)
0.4222	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.4132	SUB499	O-C=C-C
0.4080	SUB200	>= 4 any ring size 6
0.3376	SUB454	N(-C)(=C)
0.3198	SUB756	Cc1c(C)cccc1
0.2894	SUB598	O=C-C-C:C
0.2711	SUB640	O-C-C-C-O
0.2496	SUB644	[#1]-C-C-N-[#1]
0.2280	SUB500	N-C:C:N
0.2164	SUB572	[#1]-C-O-[#1]
0.2035	SUB703	O-C-C-C-C-C-N-C
0.1912	SUB582	O=C-C-C-O
0.1904	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.1573	SUB408	O(~C)(~P)
0.1568	SUB389	C(:C)(:N)(:N)
0.1301	SUB398	N(~C)(:C)(:C)
0.1232	SUB700	O-C-C-C-C-C(C)-C
0.1182	SUB517	[#1]-C=C-[#1]
0.1181	SUB488	N-C=N-C
0.1098	SUB242	>= 1 any ring size 9
0.0979	SUB432	C(-C)(-C)(=N)
0.0958	SUB451	C(-N)(=N)
0.0942	SUB682	O-C-C-C-C-O
0.0932	SUB393	N(~C)(~C)(~H)
0.0873	SUB137	>= 2 any ring size 4
0.0825	SUB823	CC1C(Cl)CCCC1
0.0802	SUB654	O-C:C:C-O
0.0750	SUB380	C(~N)(:N)
0.0726	SUB379	C(~N)(:C)(:N)
0.0543	SUB735	Cc1cc(C)ccc1
0.0527	SUB642	O-C-C-C=C
0.0510	SUB258	>= 2 aromatic rings
0.0425	SUB529	[#1]-N-C-[#1]
0.0242	SUB342	C(~C)(~C)(~O)
0.0213	SUB17	>= 4 N
0.0092	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.0064	SUB693	O=C-C-C-C-C-C
0.0060	SUB548	N-C:C-N
0.0046	SUB741	Oc1cc(O)ccc1
PF08403	Amino acid permease N-terminal
1.3455	SUB38	>= 1 Cl
0.6227	SUB484	N-S-C:C
0.3209	SUB466	O=S-C-C
0.2367	SUB415	S(~C)(~O)
0.1468	SUB533	S-C:C-[#1]
0.0569	SUB384	C(~S)(:C)
0.0487	SUB532	S-C:C-C
PF00067	Cytochrome P450
1.3436	SUB158	>= 3 any ring size 5
0.8984	SUB398	N(~C)(:C)(:C)
0.4661	SUB186	>= 2 any ring size 6
0.3945	SUB257	>= 1 hetero-aromatic ring
0.2874	SUB144	>= 1 any ring size 5
0.2783	SUB17	>= 4 N
0.2747	SUB13	>= 16 C
0.2686	SUB616	N-C-C-O-C
0.2355	SUB681	O-C-C-C-C-C
0.2293	SUB573	N:C:N:C
0.2287	SUB503	N-C=C-[#1]
0.2258	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.2187	SUB504	Cl-C:C-[#1]
0.1661	SUB706	O=C-C-C-C-C(O)-C
0.1507	SUB404	N(:C)(:C)
0.1493	SUB557	C=C-C-C
0.1488	SUB435	C(-C)(-H)(=C)
0.1392	SUB39	>= 2 Cl
0.1282	SUB713	C-C(C)-C(C)-C
0.1277	SUB712	C-C(C)(C)-C-C
0.1155	SUB641	C=C-C-C-C
0.0943	SUB660	O-C-C-N-C
0.0703	SUB431	C(-C)(-C)(=C)
0.0655	SUB580	O=C-C-C-C
0.0591	SUB594	N-C-C-C-N
0.0455	SUB335	C(~C)(~C)(~C)(~C)
0.0410	SUB381	C(~O)(~O)
0.0401	SUB447	C(-H)(=C)
0.0385	SUB491	C-C-C=C
0.0214	SUB258	>= 2 aromatic rings
0.0018	SUB565	C=C-C=C
PF00191	Annexin
1.3095	SUB253	>= 1 unsaturated non-aromatic carbon-only ring size 10
1.2513	SUB840	CC1CC(C)CC1
0.3717	SUB243	>= 1 saturated or aromatic carbon-only ring size 9
PF00160	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
1.2755	SUB603	O=C-C-N-C
PF00266	Aminotransferase class-V
1.2712	SUB498	O-C:C:N
1.1287	SUB567	O-C-C-N
0.8566	SUB588	N-C:C-O-[#1]
0.3515	SUB444	C(-C)(=O)
0.0943	SUB421	C=O
PF00074	Pancreatic ribonuclease
1.2692	SUB694	O=C-C-C-C-C-O
0.5760	SUB360	C(~C)(:N)(:N)
0.2067	SUB20	>= 2 O
0.1661	SUB457	P(-O)(=O)
0.1529	SUB412	P(~O)(~O)
0.1052	SUB692	O-C-C-C-C-C-N
0.0664	SUB426	P=O
0.0124	SUB646	O=C-N-C-C
0.0064	SUB31	>= 1 P
PF01007	Inward rectifier potassium channel
1.2638	SUB336	C(~C)(~C)(~C)(~H)
0.6191	SUB458	S(-C)(=O)
0.5737	SUB306	N-S
0.5476	SUB415	S(~C)(~O)
0.4701	SUB452	C(-N)(=O)
0.1570	SUB647	O=C-N-C-[#1]
0.0939	SUB614	C-N-C-C-C
0.0486	SUB376	C(~N)(~N)
PF02823	ATP synthase, Delta/Epsilon chain, beta-sandwich domain
1.2614	SUB364	C(~F)(~F)
0.3480	SUB25	>= 2 F
PF00497	Bacterial extracellular solute-binding proteins, family 3
1.2502	SUB656	O-C-C-C:C
1.0798	SUB337	C(~C)(~C)(~C)(~N)
0.5921	SUB286	C-N
0.5256	SUB15	>= 1 N
0.0866	SUB284	C-H
0.0489	SUB366	C(~H)(~N)
PF00146	NADH dehydrogenase
1.2353	SUB364	C(~F)(~F)
0.2876	SUB25	>= 2 F
PF00194	Eukaryotic-type carbonic anhydrase
1.2310	SUB306	N-S
0.6914	SUB459	S(-O)(=O)
0.6256	SUB284	C-H
0.6131	SUB16	>= 2 N
0.4720	SUB460	S(=O)(=O)
0.3992	SUB19	>= 1 O
0.2651	SUB20	>= 2 O
0.2522	SUB484	N-S-C:C
PF00089	Trypsin
1.2168	SUB489	N-C=N-[#1]
0.7478	SUB208	>= 5 saturated or aromatic carbon-only ring size 6
0.7040	SUB693	O=C-C-C-C-C-C
0.6969	SUB262	>= 4 aromatic rings
0.6712	SUB200	>= 4 any ring size 6
0.6022	SUB577	N=C-C:C-[#1]
0.5404	SUB459	S(-O)(=O)
0.5320	SUB603	O=C-C-N-C
0.3766	SUB680	C-C-C-C-C-C
0.3616	SUB347	C(~C)(~H)(~O)
0.2857	SUB673	O=C-C=C-[#1]
0.2778	SUB348	C(~C)(~H)(~O)(~O)
0.2588	SUB594	N-C-C-C-N
0.2521	SUB179	>= 1 any ring size 6
0.2514	SUB451	C(-N)(=N)
0.2435	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.1828	SUB439	C(-C)(-N)(=N)
0.1521	SUB336	C(~C)(~C)(~C)(~H)
0.1313	SUB529	[#1]-N-C-[#1]
0.0952	SUB2	>= 8 H
0.0845	SUB433	C(-C)(-C)(=O)
PF00375	Sodium:dicarboxylate symporter family
1.2104	SUB537	O=C-C-N
0.3090	SUB686	O=C-C-C-C-N
0.0296	SUB339	C(~C)(~C)(~H)(~N)
PF00133	tRNA synthetases class I (I, L, M and V), 
1.1703	SUB336	C(~C)(~C)(~C)(~H)
0.1300	SUB537	O=C-C-N
0.0106	SUB339	C(~C)(~C)(~H)(~N)
PF00282	Pyridoxal-dependent decarboxylase conserved domain
1.1632	SUB686	O=C-C-C-C-N
1.1078	SUB567	O-C-C-N
0.5371	SUB591	C-C:C-O-[#1]
0.3974	SUB704	O-C-C-C-C-C(N)-C
0.1509	SUB373	C(~H)(:C)(:N)
0.1274	SUB578	C:C-N-C:C
0.0424	SUB536	O=C-C-C
0.0118	SUB449	C(-H)(=O)
PF07562	Nine Cysteines Domain of family 3 GPCR
1.1505	SUB657	C-C-N-C-C
0.2431	SUB339	C(~C)(~C)(~H)(~N)
PF00130	Phorbol esters/diacylglycerol binding domain (C1 domain), 
1.1340	SUB615	C-C-O-C-C
0.4586	SUB537	O=C-C-N
0.2916	SUB621	C:C-O-C-C
0.0701	SUB633	C-C-O-C:C
0.0491	SUB738	Cc1cc(N)ccc1
0.0131	SUB408	O(~C)(~P)
PF01370	NAD dependent epimerase/dehydratase family
1.1295	SUB32	>= 2 P
0.6392	SUB664	O-C-C-O-[#1]
PF01063	Aminotransferase class IV
1.1271	SUB407	O(~C)(~H)
0.3501	SUB441	C(-C)(-O)(=O)
0.1189	SUB309	O-H
0.1055	SUB453	C(-O)(=O)
0.0336	SUB567	O-C-C-N
0.0039	SUB618	C-C-C-O-[#1]
PF01048	Phosphorylase superfamily
1.1100	SUB242	>= 1 any ring size 9
0.4491	SUB488	N-C=N-C
0.3134	SUB548	N-C:C-N
0.2385	SUB520	N=C-N-C
0.1324	SUB597	N=C-N-C-C
0.0536	SUB594	N-C-C-C-N
0.0276	SUB500	N-C:C:N
0.0133	SUB451	C(-N)(=N)
PF07645	Calcium-binding EGF domain
1.1053	SUB172	>= 5 any ring size 5
0.6408	SUB422	C=S
0.5583	SUB406	O(~C)(~C)
0.5446	SUB756	Cc1c(C)cccc1
0.0306	SUB615	C-C-O-C-C
PF02798	Glutathione S-transferase, N-terminal domain
1.0969	SUB686	O=C-C-C-C-N
0.9332	SUB694	O=C-C-C-C-C-O
0.4060	SUB350	C(~C)(~H)(~S)
0.2371	SUB354	C(~C)(~S)
0.1148	SUB369	C(~H)(~S)
0.0974	SUB339	C(~C)(~C)(~H)(~N)
0.0047	SUB294	C-S
PF00001	7 transmembrane receptor (rhodopsin family), 
1.0949	SUB841	CC1CC(O)CC1
0.9204	SUB757	Cc1c(O)cccc1
0.8538	SUB410	O(:C)(:C)
0.7973	SUB653	O-C:C:C-N
0.7580	SUB606	O=C-C-O-C
0.6866	SUB821	CC1C(S)CCCC1
0.6426	SUB3	>= 16 H
0.6285	SUB545	O-C:C-O
0.6267	SUB862	CC1C(O)CCC1
0.5778	SUB392	N(~C)(~C)(~C)
0.5185	SUB762	Oc1c(O)cccc1
0.5032	SUB675	N-C-N-C:C
0.4983	SUB801	CC1CC(N)CCC1
0.4757	SUB193	>= 3 any ring size 6
0.4364	SUB340	C(~C)(~C)(~H)(~O)
0.4061	SUB534	S-C:C-N
0.3743	SUB201	>= 4 saturated or aromatic carbon-only ring size 6
0.3410	SUB536	O=C-C-C
0.3359	SUB800	CC1CC(S)CCC1
0.3329	SUB13	>= 16 C
0.3308	SUB772	Nc1c(Cl)cccc1
0.3250	SUB579	C-C:C-C:C
0.3209	SUB346	C(~C)(~H)(~N)
0.3094	SUB668	C=C-C-O-[#1]
0.2997	SUB400	N(~H)(:C)
0.2917	SUB529	[#1]-N-C-[#1]
0.2812	SUB792	NC1CCC(N)CC1
0.2789	SUB356	C(~C)(:C)
0.2748	SUB659	C-C-S-C-C
0.2709	SUB328	C(~Br)(~C)
0.2692	SUB736	Cc1cc(O)ccc1
0.2612	SUB352	C(~C)(~N)
0.2573	SUB639	O-C-C-C-N
0.2551	SUB528	C:C:N-[#1]
0.2423	SUB406	O(~C)(~C)
0.2422	SUB572	[#1]-C-O-[#1]
0.2412	SUB366	C(~H)(~N)
0.2409	SUB18	>= 8 N
0.2323	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.2295	SUB44	>= 1 Br
0.2259	SUB632	O-C:C-O-[#1]
0.2227	SUB338	C(~C)(~C)(~C)(~O)
0.2219	SUB451	C(-N)(=N)
0.2156	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.2061	SUB180	>= 1 saturated or aromatic carbon-only ring size 6
0.2042	SUB387	C(:C)(:C)(:N)
0.2008	SUB371	C(~H)(:C)
0.1999	SUB256	>= 1 aromatic ring
0.1979	SUB17	>= 4 N
0.1949	SUB375	C(~H)(~H)(~H)
0.1878	SUB298	C-Br
0.1713	SUB359	C(~C)(:N)
0.1616	SUB300	N-H
0.1615	SUB759	Cc1c(N)cccc1
0.1604	SUB442	C(-C)(=C)
0.1595	SUB625	O=C-C:C-N
0.1541	SUB685	O=C-C-C-C-C
0.1514	SUB419	C=N
0.1512	SUB496	C-N-C:C
0.1473	SUB286	C-N
0.1446	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.1408	SUB608	N-C-C-C:C
0.1404	SUB337	C(~C)(~C)(~C)(~N)
0.1319	SUB417	C=C
0.1285	SUB620	O-C-C=C-C
0.1268	SUB144	>= 1 any ring size 5
0.1265	SUB189	>= 2 saturated or aromatic heteroatom-containing ring size 6
0.1235	SUB567	O-C-C-N
0.1231	SUB401	N(~H)(:C)(:C)
0.1210	SUB697	C-C-C-C-C-C-C-C
0.1100	SUB586	C-C:C-N-C
0.1097	SUB642	O-C-C-C=C
0.1046	SUB560	O-C-N-[#1]
0.1023	SUB600	[#1]-C-C=C-[#1]
0.0951	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.0943	SUB657	C-C-N-C-C
0.0943	SUB421	C=O
0.0933	SUB388	C(:C)(:N)
0.0928	SUB147	>= 1 saturated or aromatic heteroatom-containing ring size 5
0.0907	SUB613	N-C-O-C-C
0.0863	SUB15	>= 1 N
0.0796	SUB436	C(-C)(-H)(=N)
0.0796	SUB582	O=C-C-C-O
0.0770	SUB259	>= 2 hetero-aromatic rings
0.0760	SUB499	O-C=C-C
0.0727	SUB684	N-C-C-C-C-C
0.0700	SUB780	CC1CCC(N)CC1
0.0682	SUB651	O=C-N-C=O
0.0660	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.0659	SUB200	>= 4 any ring size 6
0.0658	SUB658	C-N-C:C-C
0.0622	SUB386	C(:C)(:C)(:C)
0.0605	SUB546	N-C:C-C
0.0474	SUB656	O-C-C-C:C
0.0456	SUB575	O-C-C:C-C
0.0456	SUB638	O-C-C-C-C
0.0440	SUB707	O=C-C-C-C-C(=O)-C
0.0405	SUB629	C-N-C-C:C
0.0401	SUB394	N(~C)(~H)
0.0384	SUB715	Cc1ccc(O)cc1
0.0378	SUB444	C(-C)(=O)
0.0355	SUB447	C(-H)(=C)
0.0316	SUB251	>= 1 saturated or aromatic nitrogen-containing ring size 10
0.0314	SUB630	S-C:C:C-N
0.0290	SUB524	N:C:C-C
0.0193	SUB834	NC1C(N)CCCC1
0.0183	SUB494	O=C-C:C
0.0176	SUB835	NC1C(Cl)CCCC1
0.0120	SUB358	C(~C)(:C)(:N)
0.0120	SUB549	O-C-C:C
0.0118	SUB372	C(~H)(:C)(:C)
0.0113	SUB252	>= 1 saturated or aromatic heteroatom-containing ring size 10
0.0100	SUB609	C-C-C-C:C
0.0038	SUB771	Nc1c(N)cccc1
0.0033	SUB614	C-N-C-C-C
0.0032	SUB443	C(-C)(=N)
0.0018	SUB433	C(-C)(-C)(=O)
0.0016	SUB378	C(~N)(:C)(:C)
0.0007	SUB607	O-C:C-C-C
0.0001	SUB571	C:C-C-C
PF08725	Integrin beta cytoplasmic domain
1.0837	SUB4	>= 32 H
0.2609	SUB350	C(~C)(~H)(~S)
0.1571	SUB369	C(~H)(~S)
PF01490	Transmembrane amino acid transporter protein
1.0768	SUB537	O=C-C-N
0.0185	SUB529	[#1]-N-C-[#1]
PF00248	Aldo/keto reductase family
1.0699	SUB32	>= 2 P
0.6181	SUB567	O-C-C-N
0.4784	SUB629	C-N-C-C:C
0.3738	SUB407	O(~C)(~H)
0.3674	SUB444	C(-C)(=O)
0.3017	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.2467	SUB580	O=C-C-C-C
0.2280	SUB537	O=C-C-N
0.2043	SUB284	C-H
0.1312	SUB1	>= 4 H
0.1157	SUB421	C=O
0.0609	SUB288	C-F
0.0135	SUB10	>= 2 C
PF00587	tRNA synthetase class II core domain (G, H, P, S and T), 
1.0618	SUB537	O=C-C-N
PF00368	Hydroxymethylglutaryl-coenzyme A reductase
1.0586	SUB640	O-C-C-C-O
0.9436	SUB618	C-C-C-O-[#1]
0.1861	SUB340	C(~C)(~C)(~H)(~O)
PF09396	Thrombin light chain
1.0581	SUB193	>= 3 any ring size 6
PF03493	Calcium-activated BK potassium channel alpha subunit
1.0516	SUB249	>= 1 any ring size 10
0.3807	SUB343	C(~C)(~Cl)
0.0845	SUB295	C-Cl
PF01124	MAPEG family
1.0339	SUB414	S(~C)(~H)
PF01023	S-100/ICaBP type calcium binding domain
1.0302	SUB633	C-C-O-C:C
0.2501	SUB643	O-C-C-C=O
0.2037	SUB621	C:C-O-C-C
0.0207	SUB757	Cc1c(O)cccc1
PF05652	Scavenger mRNA decapping enzyme (DcpS),  N-terminal
1.0268	SUB408	O(~C)(~P)
PF02159	Oestrogen receptor
1.0087	SUB346	C(~C)(~H)(~N)
0.7121	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.5376	SUB180	>= 1 saturated or aromatic carbon-only ring size 6
0.1411	SUB357	C(~C)(:C)(:C)
0.0834	SUB366	C(~H)(~N)
0.0800	SUB710	C-C(C)-C-C-C
0.0743	SUB711	C-C-C(C)-C-C
0.0260	SUB342	C(~C)(~C)(~O)
PF00576	HIUase/Transthyretin family
0.9925	SUB656	O-C-C-C:C
0.8226	SUB407	O(~C)(~H)
0.2381	SUB309	O-H
0.1574	SUB668	C=C-C-O-[#1]
PF01401	Angiotensin-converting enzyme
0.9883	SUB703	O-C-C-C-C-C-N-C
0.8619	SUB441	C(-C)(-O)(=O)
0.8582	SUB647	O=C-N-C-[#1]
0.5807	SUB700	O-C-C-C-C-C(C)-C
0.3543	SUB339	C(~C)(~C)(~H)(~N)
0.2518	SUB381	C(~O)(~O)
0.1162	SUB616	N-C-C-O-C
0.0592	SUB453	C(-O)(=O)
PF00068	Phospholipase A2
0.9849	SUB686	O=C-C-C-C-N
PF00903	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
0.9712	SUB695	O=C-C-C-C-C=O
0.2864	SUB369	C(~H)(~S)
0.1159	SUB350	C(~C)(~H)(~S)
PF00071	Ras family
0.9629	SUB398	N(~C)(:C)(:C)
0.8525	SUB625	O=C-C:C-N
0.3073	SUB536	O=C-C-C
0.2873	SUB640	O-C-C-C-O
0.1616	SUB494	O=C-C:C
0.1438	SUB618	C-C-C-O-[#1]
0.0849	SUB441	C(-C)(-O)(=O)
PF00225	Kinesin motor domain
0.9546	SUB683	O-C-C-C-C-N
0.1155	SUB629	C-N-C-C:C
0.0229	SUB432	C(-C)(-C)(=N)
PF06512	Sodium ion transport-associated
0.9526	SUB598	O=C-C-C:C
0.4465	SUB341	C(~C)(~C)(~N)
0.3662	SUB300	N-H
0.2427	SUB666	N-C:C-C-C
0.1941	SUB375	C(~H)(~H)(~H)
0.1907	SUB605	C-O-C-C:C
0.1529	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0715	SUB619	C:C-C-C:C
0.0644	SUB371	C(~H)(:C)
0.0545	SUB12	>= 8 C
0.0463	SUB517	[#1]-C=C-[#1]
0.0046	SUB347	C(~C)(~H)(~O)
0.0030	SUB372	C(~H)(:C)(:C)
PF00549	CoA-ligase
0.9491	SUB688	O=C-C-C-C=O
PF02668	Taurine catabolism dioxygenase TauD, TfdA family
0.9442	SUB687	O=C-C-C-C-O
PF00171	Aldehyde dehydrogenase family
0.9419	SUB673	O=C-C=C-[#1]
0.5926	SUB668	C=C-C-O-[#1]
0.5597	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.4850	SUB13	>= 16 C
0.3621	SUB600	[#1]-C-C=C-[#1]
0.3399	SUB158	>= 3 any ring size 5
0.2624	SUB22	>= 8 O
0.2557	SUB431	C(-C)(-C)(=C)
0.1812	SUB347	C(~C)(~H)(~O)
0.1121	SUB576	O-C-C:C-O
0.0522	SUB683	O-C-C-C-C-N
0.0380	SUB682	O-C-C-C-C-O
PF00854	POT family
0.9327	SUB132	>= 1 saturated or aromatic nitrogen-containing ring size 4
0.2926	SUB130	>= 1 any ring size 4
0.1128	SUB133	>= 1 saturated or aromatic heteroatom-containing ring size 4
PF00478	IMP dehydrogenase / GMP reductase domain
0.9287	SUB242	>= 1 any ring size 9
0.5914	SUB147	>= 1 saturated or aromatic heteroatom-containing ring size 5
0.4999	SUB390	C(:N)(:N)
0.1399	SUB682	O-C-C-C-C-O
0.1130	SUB573	N:C:N:C
0.1126	SUB505	N:C:N-C
PF00351	Biopterin-dependent aromatic amino acid hydroxylase
0.9284	SUB537	O=C-C-N
0.8594	SUB567	O-C-C-N
0.2607	SUB618	C-C-C-O-[#1]
0.1182	SUB529	[#1]-N-C-[#1]
PF12497	Estrogen receptor beta
0.9219	SUB778	CC1CCC(O)CC1
PF01607	Chitin binding Peritrophin-A domain
0.9040	SUB572	[#1]-C-O-[#1]
PF00005	ABC transporter
0.9040	SUB336	C(~C)(~C)(~C)(~H)
0.7455	SUB716	Cc1ccc(S)cc1
0.5719	SUB3	>= 16 H
0.4864	SUB691	O-C-C-C-C-C-O
0.4427	SUB259	>= 2 hetero-aromatic rings
0.4129	SUB582	O=C-C-C-O
0.4091	SUB505	N:C:N-C
0.3623	SUB378	C(~N)(:C)(:C)
0.3257	SUB258	>= 2 aromatic rings
0.3058	SUB672	O=C-C=C-C
0.2790	SUB779	CC1CCC(S)CC1
0.2763	SUB647	O=C-N-C-[#1]
0.2393	SUB660	O-C-C-N-C
0.1729	SUB193	>= 3 any ring size 6
0.1717	SUB657	C-C-N-C-C
0.1539	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.1365	SUB646	O=C-N-C-C
0.1099	SUB622	N-C:C:C:N
0.1040	SUB17	>= 4 N
0.0965	SUB387	C(:C)(:C)(:N)
0.0826	SUB602	N-C:C:C-N
0.0717	SUB643	O-C-C-C=O
0.0665	SUB21	>= 4 O
0.0664	SUB346	C(~C)(~H)(~N)
0.0658	SUB261	>= 3 hetero-aromatic rings
0.0619	SUB541	C-N-C-[#1]
0.0596	SUB757	Cc1c(O)cccc1
0.0532	SUB688	O=C-C-C-C=O
0.0463	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0369	SUB572	[#1]-C-O-[#1]
0.0277	SUB594	N-C-C-C-N
0.0062	SUB385	C(:C)(:C)
0.0033	SUB699	O-C-C-C-C-C-C-C
0.0032	SUB366	C(~H)(~N)
PF08240	Alcohol dehydrogenase GroES-like domain
0.8955	SUB622	N-C:C:C:N
0.7257	SUB602	N-C:C:C-N
0.3063	SUB695	O=C-C-C-C-C=O
0.0753	SUB446	C(-H)(-N)(=C)
PF00186	Dihydrofolate reductase
0.8923	SUB17	>= 4 N
0.5115	SUB379	C(~N)(:C)(:N)
0.4470	SUB451	C(-N)(=N)
0.2408	SUB394	N(~C)(~H)
0.2104	SUB675	N-C-N-C:C
0.0812	SUB488	N-C=N-C
PF02932	Neurotransmitter-gated ion-channel transmembrane region
0.8863	SUB207	>= 5 any ring size 6
0.8269	SUB228	>= 1 any ring size 8
0.3817	SUB214	>= 1 any ring size 7
0.3026	SUB16	>= 2 N
0.2971	SUB353	C(~C)(~O)
0.2864	SUB825	OC1C(O)CCCC1
0.2761	SUB709	C-C(C)-C-C
0.2754	SUB739	Cc1cc(Cl)ccc1
0.2562	SUB793	NC1CCC(Cl)CC1
0.2335	SUB287	C-O
0.2260	SUB780	CC1CCC(N)CC1
0.2081	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.1923	SUB151	>= 2 any ring size 5
0.1853	SUB375	C(~H)(~H)(~H)
0.1640	SUB285	C-C
0.1611	SUB392	N(~C)(~C)(~C)
0.1458	SUB802	CC1CC(Cl)CCC1
0.1280	SUB345	C(~C)(~H)
0.0739	SUB295	C-Cl
0.0732	SUB288	C-F
0.0681	SUB581	O=C-C-C-N
0.0597	SUB38	>= 1 Cl
0.0527	SUB577	N=C-C:C-[#1]
0.0427	SUB712	C-C(C)(C)-C-C
0.0242	SUB19	>= 1 O
0.0182	SUB334	C(~C)(~C)(~C)
0.0145	SUB701	O-C-C-C-C-C-O-C
0.0054	SUB343	C(~C)(~Cl)
PF00962	Adenosine/AMP deaminase
0.8818	SUB379	C(~N)(:C)(:N)
0.4877	SUB486	N:C:C:N
0.4119	SUB500	N-C:C:N
0.1615	SUB548	N-C:C-N
PF02931	Neurotransmitter-gated ion-channel ligand binding domain
0.8781	SUB207	>= 5 any ring size 6
0.7637	SUB214	>= 1 any ring size 7
0.5191	SUB24	>= 1 F
0.5173	SUB16	>= 2 N
0.4277	SUB712	C-C(C)(C)-C-C
0.3494	SUB793	NC1CCC(Cl)CC1
0.3302	SUB392	N(~C)(~C)(~C)
0.3265	SUB151	>= 2 any ring size 5
0.3164	SUB709	C-C(C)-C-C
0.3141	SUB780	CC1CCC(N)CC1
0.2610	SUB353	C(~C)(~O)
0.2271	SUB295	C-Cl
0.1971	SUB228	>= 1 any ring size 8
0.1925	SUB577	N=C-C:C-[#1]
0.1829	SUB287	C-O
0.1137	SUB345	C(~C)(~H)
0.1072	SUB730	Nc1ccc(Cl)cc1
0.1064	SUB589	O=C-C-C=O
0.1040	SUB804	OC1CC(O)CCC1
0.0981	SUB38	>= 1 Cl
0.0965	SUB375	C(~H)(~H)(~H)
0.0950	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0875	SUB288	C-F
0.0801	SUB701	O-C-C-C-C-C-O-C
0.0632	SUB19	>= 1 O
0.0198	SUB581	O=C-C-C-N
0.0196	SUB739	Cc1cc(Cl)ccc1
0.0166	SUB802	CC1CC(Cl)CCC1
0.0089	SUB343	C(~C)(~Cl)
PF00056	lactate/malate dehydrogenase, NAD binding domain
0.8767	SUB158	>= 3 any ring size 5
0.1416	SUB440	C(-C)(-N)(=O)
0.0879	SUB407	O(~C)(~H)
0.0707	SUB32	>= 2 P
PF00930	Dipeptidyl peptidase IV (DPP IV),  N-terminal region
0.8713	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.1740	SUB702	O-C-C-C-C-C(O)-C
PF03770	Inositol polyphosphate kinase 
0.8678	SUB31	>= 1 P
0.0593	SUB315	O-P
0.0006	SUB457	P(-O)(=O)
PF02267	ADP-ribosyl cyclase
0.8589	SUB448	C(-H)(=N)
0.2397	SUB613	N-C-O-C-C
PF00858	Amiloride-sensitive sodium channel
0.8533	SUB379	C(~N)(:C)(:N)
0.7496	SUB486	N:C:C:N
0.4369	SUB578	C:C-N-C:C
PF03098	Animal haem peroxidase
0.8528	SUB447	C(-H)(=C)
0.5621	SUB417	C=C
0.5416	SUB20	>= 2 O
0.4850	SUB517	[#1]-C=C-[#1]
0.3884	SUB453	C(-O)(=O)
0.1401	SUB672	O=C-C=C-C
0.1398	SUB598	O=C-C-C:C
0.1269	SUB450	C(-N)(=C)
0.1221	SUB503	N-C=C-[#1]
0.1054	SUB309	O-H
0.0676	SUB600	[#1]-C-C=C-[#1]
0.0668	SUB435	C(-C)(-H)(=C)
0.0636	SUB375	C(~H)(~H)(~H)
0.0547	SUB441	C(-C)(-O)(=O)
0.0092	SUB19	>= 1 O
PF00153	Mitochondrial carrier protein
0.8417	SUB567	O-C-C-N
0.5118	SUB32	>= 2 P
0.4350	SUB580	O=C-C-C-C
0.3762	SUB686	O=C-C-C-C-N
0.2017	SUB309	O-H
0.0859	SUB638	O-C-C-C-C
0.0650	SUB441	C(-C)(-O)(=O)
0.0573	SUB683	O-C-C-C-C-N
0.0506	SUB21	>= 4 O
PF00209	Sodium:neurotransmitter symporter family
0.8379	SUB579	C-C:C-C:C
0.7043	SUB346	C(~C)(~H)(~N)
0.5256	SUB529	[#1]-N-C-[#1]
0.4086	SUB366	C(~H)(~N)
0.2738	SUB619	C:C-C-C:C
0.2168	SUB392	N(~C)(~C)(~C)
0.1673	SUB352	C(~C)(~N)
0.1371	SUB644	[#1]-C-C-N-[#1]
0.1123	SUB286	C-N
0.0832	SUB604	C-C:C:C-C
0.0639	SUB357	C(~C)(:C)(:C)
0.0633	SUB15	>= 1 N
0.0614	SUB214	>= 1 any ring size 7
0.0514	SUB692	O-C-C-C-C-C-N
0.0488	SUB697	C-C-C-C-C-C-C-C
0.0434	SUB372	C(~H)(:C)(:C)
0.0307	SUB394	N(~C)(~H)
0.0277	SUB609	C-C-C-C:C
0.0183	SUB678	C-C=C-C:C
0.0156	SUB471	C:C-C=C
0.0056	SUB635	C-C-C:C-C
PF00026	Eukaryotic aspartyl protease
0.8352	SUB696	O=C-C-C-C-C-N
0.0590	SUB594	N-C-C-C-N
0.0166	SUB646	O=C-N-C-C
0.0003	SUB647	O=C-N-C-[#1]
PF00233	3"5"-cyclic nucleotide phosphodiesterase
0.8242	SUB703	O-C-C-C-C-C-N-C
0.7510	SUB252	>= 1 saturated or aromatic heteroatom-containing ring size 10
0.6777	SUB369	C(~H)(~S)
0.5436	SUB631	O-C:C-O-C
0.4625	SUB536	O=C-C-C
0.3752	SUB443	C(-C)(=N)
0.3705	SUB539	N=C-C-C
0.3295	SUB537	O=C-C-N
0.3053	SUB500	N-C:C:N
0.2519	SUB356	C(~C)(:C)
0.2192	SUB621	C:C-O-C-C
0.2131	SUB597	N=C-N-C-C
0.1777	SUB444	C(-C)(=O)
0.1741	SUB144	>= 1 any ring size 5
0.1404	SUB419	C=N
0.1306	SUB256	>= 1 aromatic ring
0.1270	SUB633	C-C-O-C:C
0.1033	SUB421	C=O
0.0978	SUB439	C(-C)(-N)(=N)
0.0711	SUB353	C(~C)(~O)
0.0663	SUB603	O=C-C-N-C
0.0554	SUB299	C-I
0.0443	SUB440	C(-C)(-N)(=O)
0.0239	SUB554	O=C-C=C
0.0101	SUB454	N(-C)(=C)
0.0087	SUB452	C(-N)(=O)
PF00149	Calcineurin-like phosphoesterase
0.8091	SUB14	>= 32 C
0.4680	SUB4	>= 32 H
0.3398	SUB698	C-C-C-C-C-C(C)-C
0.2164	SUB594	N-C-C-C-N
PF07992	Pyridine nucleotide-disulphide oxidoreductase
0.8086	SUB18	>= 8 N
0.4105	SUB22	>= 8 O
0.3416	SUB21	>= 4 O
0.0066	SUB452	C(-N)(=O)
PF00128	Alpha amylase, catalytic domain
0.8084	SUB339	C(~C)(~C)(~H)(~N)
0.3798	SUB702	O-C-C-C-C-C(O)-C
0.3494	SUB618	C-C-C-O-[#1]
0.0993	SUB381	C(~O)(~O)
PF00117	Glutamine amidotransferase class-I
0.7997	SUB529	[#1]-N-C-[#1]
PF01532	Glycosyl hydrolase family 47
0.7953	SUB682	O-C-C-C-C-O
PF00211	Adenylate and Guanylate cyclase catalytic domain
0.7924	SUB424	N=O
0.4771	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.4015	SUB17	>= 4 N
0.3022	SUB703	O-C-C-C-C-C-N-C
0.1353	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
PF00305	Lipoxygenase
0.7822	SUB375	C(~H)(~H)(~H)
0.0805	SUB679	C-C-C=C-C
0.0663	SUB431	C(-C)(-C)(=C)
0.0493	SUB711	C-C-C(C)-C-C
0.0288	SUB661	C-C=C-C-C
PF00520	Ion transport protein
0.7768	SUB799	CC1CC(O)CCC1
0.7234	SUB288	C-F
0.4623	SUB666	N-C:C-C-C
0.4612	SUB651	O=C-N-C=O
0.4248	SUB258	>= 2 aromatic rings
0.4045	SUB460	S(=O)(=O)
0.3549	SUB200	>= 4 any ring size 6
0.3394	SUB486	N:C:C:N
0.3118	SUB698	C-C-C-C-C-C(C)-C
0.3065	SUB392	N(~C)(~C)(~C)
0.3046	SUB438	C(-C)(-N)(=C)
0.2756	SUB546	N-C:C-C
0.2014	SUB300	N-H
0.1913	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.1820	SUB700	O-C-C-C-C-C(C)-C
0.1725	SUB760	Cc1c(Cl)cccc1
0.1639	SUB336	C(~C)(~C)(~C)(~H)
0.1581	SUB675	N-C-N-C:C
0.1293	SUB459	S(-O)(=O)
0.1184	SUB180	>= 1 saturated or aromatic carbon-only ring size 6
0.1145	SUB712	C-C(C)(C)-C-C
0.1005	SUB709	C-C(C)-C-C
0.0945	SUB19	>= 1 O
0.0885	SUB25	>= 2 F
0.0788	SUB377	C(~N)(:C)
0.0702	SUB4	>= 32 H
0.0534	SUB367	C(~H)(~O)
0.0492	SUB295	C-Cl
0.0466	SUB394	N(~C)(~H)
0.0311	SUB339	C(~C)(~C)(~H)(~N)
0.0294	SUB3	>= 16 H
0.0204	SUB699	O-C-C-C-C-C-C-C
0.0121	SUB614	C-N-C-C-C
0.0071	SUB343	C(~C)(~Cl)
0.0068	SUB606	O=C-C-O-C
0.0020	SUB710	C-C(C)-C-C-C
PF00105	Zinc finger, C4 type (two domains), 
0.7714	SUB715	Cc1ccc(O)cc1
0.6959	SUB720	Oc1ccc(O)cc1
0.5658	SUB522	C:N-C-[#1]
0.5139	SUB738	Cc1cc(N)ccc1
0.4655	SUB48	>= 2 I
0.3743	SUB680	C-C-C-C-C-C
0.3523	SUB467	N#C-C=C
0.2977	SUB13	>= 16 C
0.2968	SUB621	C:C-O-C-C
0.2960	SUB441	C(-C)(-O)(=O)
0.2621	SUB840	CC1CC(C)CC1
0.2579	SUB633	C-C-O-C:C
0.2454	SUB735	Cc1cc(C)ccc1
0.1963	SUB605	C-O-C-C:C
0.1761	SUB587	C-S-C-C-C
0.1538	SUB798	CC1CC(C)CCC1
0.1446	SUB461	C-C-C#C
0.1279	SUB677	N#C-C-C-C
0.0755	SUB381	C(~O)(~O)
0.0646	SUB690	O-C-C-C-C-C-C
0.0536	SUB658	C-N-C:C-C
0.0509	SUB407	O(~C)(~H)
0.0400	SUB629	C-N-C-C:C
0.0381	SUB517	[#1]-C=C-[#1]
0.0360	SUB586	C-C:C-N-C
0.0347	SUB444	C(-C)(=O)
0.0295	SUB672	O=C-C=C-C
0.0276	SUB595	C-O-C-C=C
0.0230	SUB667	C=C-C-O-C
0.0038	SUB646	O=C-N-C-C
PF00291	Pyridoxal-phosphate dependent enzyme
0.7702	SUB643	O-C-C-C=O
0.3281	SUB578	C:C-N-C:C
0.3000	SUB341	C(~C)(~C)(~N)
0.0985	SUB704	O-C-C-C-C-C(N)-C
0.0610	SUB582	O=C-C-C-O
PF00763	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
0.7659	SUB674	O=C-C=C-N
PF00091	Tubulin/FtsZ family, GTPase domain
0.7655	SUB825	OC1C(O)CCCC1
0.5940	SUB595	C-O-C-C=C
0.5010	SUB712	C-C(C)(C)-C-C
0.4435	SUB667	C=C-C-O-C
0.3707	SUB465	N-C-C=C
0.3330	SUB335	C(~C)(~C)(~C)(~C)
0.3301	SUB582	O=C-C-C-O
0.1819	SUB433	C(-C)(-C)(=O)
0.0854	SUB702	O-C-C-C-C-C(O)-C
0.0572	SUB643	O-C-C-C=O
0.0346	SUB640	O-C-C-C-O
0.0026	SUB540	N=C-C-[#1]
PF07690	Major Facilitator Superfamily
0.7641	SUB536	O=C-C-C
0.7103	SUB433	C(-C)(-C)(=O)
0.6438	SUB631	O-C:C-O-C
0.5803	SUB339	C(~C)(~C)(~H)(~N)
0.4547	SUB708	O=C-C-C-C-C(N)-C
0.2846	SUB249	>= 1 any ring size 10
0.1701	SUB441	C(-C)(-O)(=O)
0.0289	SUB545	O-C:C-O
PF00135	Carboxylesterase
0.7628	SUB375	C(~H)(~H)(~H)
0.2366	SUB406	O(~C)(~C)
0.1908	SUB392	N(~C)(~C)(~C)
PF02919	Eukaryotic DNA topoisomerase I, DNA binding fragment
0.7557	SUB252	>= 1 saturated or aromatic heteroatom-containing ring size 10
0.4897	SUB759	Cc1c(N)cccc1
0.1768	SUB664	O-C-C-O-[#1]
0.1432	SUB463	O-C-C=O
PF00709	Adenylosuccinate synthetase
0.7554	SUB529	[#1]-N-C-[#1]
PF03953	Tubulin C-terminal domain
0.7464	SUB712	C-C(C)(C)-C-C
0.3983	SUB667	C=C-C-O-C
0.3603	SUB433	C(-C)(-C)(=O)
0.3319	SUB595	C-O-C-C=C
0.2528	SUB825	OC1C(O)CCCC1
0.1714	SUB465	N-C-C=C
0.1230	SUB640	O-C-C-C-O
0.1148	SUB335	C(~C)(~C)(~C)(~C)
0.0523	SUB702	O-C-C-C-C-C(O)-C
0.0491	SUB643	O-C-C-C=O
0.0437	SUB582	O=C-C-C-O
0.0014	SUB540	N=C-C-[#1]
PF00104	Ligand-binding domain of nuclear hormone receptor
0.7430	SUB715	Cc1ccc(O)cc1
0.7249	SUB712	C-C(C)(C)-C-C
0.3970	SUB706	O=C-C-C-C-C(O)-C
0.2986	SUB738	Cc1cc(N)ccc1
0.2923	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.2831	SUB672	O=C-C=C-C
0.2417	SUB13	>= 16 C
0.2266	SUB335	C(~C)(~C)(~C)(~C)
0.1677	SUB461	C-C-C#C
0.1617	SUB840	CC1CC(C)CC1
0.1292	SUB629	C-N-C-C:C
0.1266	SUB441	C(-C)(-O)(=O)
0.0957	SUB798	CC1CC(C)CCC1
0.0902	SUB522	C:N-C-[#1]
0.0652	SUB720	Oc1ccc(O)cc1
0.0426	SUB338	C(~C)(~C)(~C)(~O)
0.0306	SUB407	O(~C)(~H)
0.0193	SUB735	Cc1cc(C)ccc1
0.0033	SUB587	C-S-C-C-C
PF00303	Thymidylate synthase
0.7402	SUB674	O=C-C=C-N
0.5098	SUB407	O(~C)(~H)
0.4548	SUB572	[#1]-C-O-[#1]
0.3768	SUB647	O=C-N-C-[#1]
0.1305	SUB376	C(~N)(~N)
0.0891	SUB309	O-H
PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase
0.7384	SUB14	>= 32 C
0.3401	SUB606	O=C-C-O-C
0.1286	SUB568	O-C-C-O
PF00354	Pentaxin family
0.7315	SUB441	C(-C)(-O)(=O)
PF00501	AMP-binding enzyme
0.7291	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.5755	SUB682	O-C-C-C-C-O
0.2083	SUB681	O-C-C-C-C-C
0.1520	SUB663	O-C-C-O-C
PF00208	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
0.7258	SUB683	O-C-C-C-C-N
PF02882	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P), -binding domain
0.7223	SUB674	O=C-C=C-N
PF00041	Fibronectin type III domain
0.7191	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.4696	SUB572	[#1]-C-O-[#1]
PF00594	Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA),  domain
0.7139	SUB253	>= 1 unsaturated non-aromatic carbon-only ring size 10
0.6112	SUB186	>= 2 any ring size 6
0.4601	SUB460	S(=O)(=O)
0.2341	SUB459	S(-O)(=O)
0.1270	SUB603	O=C-C-N-C
0.0735	SUB697	C-C-C-C-C-C-C-C
PF00229	TNF(Tumour Necrosis Factor),  family 
0.7135	SUB706	O=C-C-C-C-C(O)-C
0.4442	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.2956	SUB694	O=C-C-C-C-C-O
0.2142	SUB672	O=C-C=C-C
0.1269	SUB378	C(~N)(:C)(:C)
0.0707	SUB340	C(~C)(~C)(~H)(~O)
0.0519	SUB550	N-C-C:C
PF00725	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
0.7130	SUB389	C(:C)(:N)(:N)
0.1119	SUB32	>= 2 P
0.0659	SUB622	N-C:C:C:N
0.0454	SUB602	N-C:C:C-N
0.0003	SUB360	C(~C)(:N)(:N)
PF02310	B12 binding domain
0.7124	SUB708	O=C-C-C-C-C(N)-C
0.5946	SUB717	Cc1ccc(N)cc1
PF00405	Transferrin
0.7108	SUB381	C(~O)(~O)
PF10613	Ligated ion channel L-glutamate- and glycine-binding site
0.7099	SUB364	C(~F)(~F)
PF00156	Phosphoribosyl transferase domain
0.7047	SUB379	C(~N)(:C)(:N)
0.4358	SUB500	N-C:C:N
0.1851	SUB486	N:C:C:N
0.1697	SUB548	N-C:C-N
PF02223	Thymidylate kinase
0.6960	SUB613	N-C-O-C-C
0.3780	SUB315	O-P
0.2309	SUB31	>= 1 P
0.2087	SUB426	P=O
0.1963	SUB457	P(-O)(=O)
0.1025	SUB703	O-C-C-C-C-C-N-C
0.0453	SUB408	O(~C)(~P)
0.0053	SUB412	P(~O)(~O)
PF00459	Inositol monophosphatase family
0.6931	SUB5	>= 1 Li
PF00143	Interferon alpha/beta domain
0.6926	SUB348	C(~C)(~H)(~O)(~O)
PF00051	Kringle domain
0.6921	SUB336	C(~C)(~C)(~C)(~H)
0.6350	SUB419	C=N
0.4474	SUB529	[#1]-N-C-[#1]
0.2721	SUB394	N(~C)(~H)
0.1774	SUB376	C(~N)(~N)
0.1552	SUB300	N-H
0.0920	SUB421	C=O
PF08674	Acetylcholinesterase tetramerisation domain
0.6907	SUB392	N(~C)(~C)(~C)
0.3710	SUB1	>= 4 H
0.2649	SUB284	C-H
0.1065	SUB375	C(~H)(~H)(~H)
PF00690	Cation transporter/ATPase, N-terminus
0.6859	SUB25	>= 2 F
0.2436	SUB354	C(~C)(~S)
0.2373	SUB406	O(~C)(~C)
0.1659	SUB295	C-Cl
0.1378	SUB466	O=S-C-C
0.1244	SUB144	>= 1 any ring size 5
0.0929	SUB595	C-O-C-C=C
0.0157	SUB667	C=C-C-O-C
PF00273	Serum albumin family
0.6854	SUB345	C(~C)(~H)
0.4154	SUB20	>= 2 O
0.3884	SUB407	O(~C)(~H)
0.3621	SUB285	C-C
0.3314	SUB10	>= 2 C
0.2681	SUB309	O-H
0.2666	SUB284	C-H
0.1132	SUB381	C(~O)(~O)
0.0924	SUB680	C-C-C-C-C-C
PF08527	Protein-arginine deiminase (PAD),  middle domain
0.6829	SUB703	O-C-C-C-C-C-N-C
0.0194	SUB696	O=C-C-C-C-C-N
PF02898	Nitric oxide synthase, oxygenase domain
0.6828	SUB407	O(~C)(~H)
0.4037	SUB16	>= 2 N
0.2151	SUB419	C=N
0.1404	SUB285	C-C
PF02166	Androgen receptor
0.6828	SUB646	O=C-N-C-C
0.3923	SUB536	O=C-C-C
0.2939	SUB801	CC1CC(N)CCC1
0.0713	SUB644	[#1]-C-C-N-[#1]
PF00048	Small cytokines (intecrine/chemokine), , interleukin-8 like
0.6717	SUB309	O-H
0.4137	SUB441	C(-C)(-O)(=O)
0.3098	SUB694	O=C-C-C-C-C-O
0.1943	SUB702	O-C-C-C-C-C(O)-C
0.0166	SUB572	[#1]-C-O-[#1]
PF02806	Alpha amylase, C-terminal all-beta domain
0.6673	SUB691	O-C-C-C-C-C-O
0.2549	SUB564	O-C-O-C
0.1677	SUB702	O-C-C-C-C-C(O)-C
0.1285	SUB618	C-C-C-O-[#1]
0.1184	SUB572	[#1]-C-O-[#1]
0.0261	SUB407	O(~C)(~H)
PF00343	Carbohydrate phosphorylase
0.6645	SUB347	C(~C)(~H)(~O)
0.6075	SUB432	C(-C)(-C)(=N)
0.5593	SUB624	O=C-C:C-C
0.4107	SUB578	C:C-N-C:C
0.0932	SUB682	O-C-C-C-C-O
0.0483	SUB407	O(~C)(~H)
0.0045	SUB367	C(~H)(~O)
0.0007	SUB793	NC1CCC(Cl)CC1
PF00755	Choline/Carnitine o-acyltransferase
0.6639	SUB541	C-N-C-[#1]
0.4021	SUB686	O=C-C-C-C-N
0.1025	SUB660	O-C-C-N-C
PF00939	Sodium:sulfate symporter transmembrane region
0.6616	SUB687	O=C-C-C-C-O
PF02866	lactate/malate dehydrogenase, alpha/beta C-terminal domain
0.6587	SUB440	C(-C)(-N)(=O)
0.5383	SUB32	>= 2 P
0.3026	SUB158	>= 3 any ring size 5
0.0710	SUB407	O(~C)(~H)
0.0177	SUB389	C(:C)(:N)(:N)
PF03073	TspO/MBR family
0.6544	SUB577	N=C-C:C-[#1]
0.3781	SUB454	N(-C)(=C)
0.3186	SUB539	N=C-C-C
0.3033	SUB346	C(~C)(~H)(~N)
0.2125	SUB612	N-C-C-N-C
0.2014	SUB392	N(~C)(~C)(~C)
0.1263	SUB599	Cl-C:C:C-C
0.1246	SUB570	N-C-C-N
0.0574	SUB432	C(-C)(-C)(=N)
0.0189	SUB366	C(~H)(~N)
0.0111	SUB592	Cl-C-C-C-C
0.0093	SUB343	C(~C)(~Cl)
0.0046	SUB551	Cl-C-C-C
0.0038	SUB443	C(-C)(=N)
0.0010	SUB363	C(~Cl)(:C)
PF00728	Glycosyl hydrolase family 20, catalytic domain
0.6448	SUB664	O-C-C-O-[#1]
0.1481	SUB568	O-C-C-O
PF00579	tRNA synthetases class I (W and Y), 
0.6389	SUB537	O=C-C-N
0.0510	SUB339	C(~C)(~C)(~H)(~N)
0.0116	SUB699	O-C-C-C-C-C-C-C
PF07885	Ion channel
0.6388	SUB547	N-C:C-[#1]
0.4027	SUB503	N-C=C-[#1]
0.2547	SUB785	OC1CCC(N)CC1
0.0732	SUB683	O-C-C-C-C-N
0.0408	SUB722	Oc1ccc(N)cc1
PF02793	Hormone receptor domain
0.6365	SUB23	>= 16 O
0.2131	SUB489	N-C=N-[#1]
0.1511	SUB695	O=C-C-C-C-C=O
PF00643	B-box zinc finger
0.6360	SUB631	O-C:C-O-C
0.2033	SUB756	Cc1c(C)cccc1
0.1904	SUB762	Oc1c(O)cccc1
0.0084	SUB545	O-C:C-O
PF03807	NADP oxidoreductase coenzyme F420-dependent
0.6334	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.3472	SUB692	O-C-C-C-C-C-N
PF00227	Proteasome subunit
0.6318	SUB277	B-O
0.4903	SUB7	>= 1 B
0.3396	SUB495	O=C-C:N
0.2665	SUB275	B-C
PF00689	Cation transporting ATPase, C-terminus
0.6310	SUB25	>= 2 F
0.2835	SUB39	>= 2 Cl
0.2276	SUB354	C(~C)(~S)
0.1733	SUB144	>= 1 any ring size 5
0.1531	SUB667	C=C-C-O-C
0.1313	SUB295	C-Cl
0.1249	SUB595	C-O-C-C=C
0.1184	SUB466	O=S-C-C
0.0377	SUB38	>= 1 Cl
0.0155	SUB406	O(~C)(~C)
PF00059	Lectin C-type domain
0.6306	SUB406	O(~C)(~C)
0.4753	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.2160	SUB381	C(~O)(~O)
0.0029	SUB367	C(~H)(~O)
PF00583	Acetyltransferase (GNAT),  family
0.6299	SUB594	N-C-C-C-N
PF00058	Low-density lipoprotein receptor repeat class B
0.6231	SUB381	C(~O)(~O)
PF00493	MCM2/3/5 family
0.6219	SUB14	>= 32 C
0.1001	SUB365	C(~F)(:C)
PF01039	Carboxyl transferase domain
0.6153	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
PF01122	Eukaryotic cobalamin-binding protein
0.6131	SUB172	>= 5 any ring size 5
0.3766	SUB738	Cc1cc(N)ccc1
0.2390	SUB60	>= 1 Co
0.1147	SUB771	Nc1c(N)cccc1
PF00023	Ankyrin repeat
0.6114	SUB695	O=C-C-C-C-C=O
0.4360	SUB681	O-C-C-C-C-C
0.3520	SUB686	O=C-C-C-C-N
0.1532	SUB694	O=C-C-C-C-C-O
PF00557	Metallopeptidase family M24
0.6041	SUB407	O(~C)(~H)
0.4405	SUB309	O-H
0.1439	SUB375	C(~H)(~H)(~H)
PF00060	Ligand-gated ion channel
0.6007	SUB686	O=C-C-C-C-N
0.4017	SUB337	C(~C)(~C)(~C)(~N)
0.2100	SUB284	C-H
0.1750	SUB345	C(~C)(~H)
0.0249	SUB287	C-O
PF03491	Serotonin (5-HT),  neurotransmitter transporter, N-terminus
0.6004	SUB3	>= 16 H
PF08491	Squalene epoxidase
0.5981	SUB250	>= 1 saturated or aromatic carbon-only ring size 10
PF00676	Dehydrogenase E1 component
0.5976	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF07686	Immunoglobulin V-set domain
0.5931	SUB647	O=C-N-C-[#1]
0.5428	SUB24	>= 1 F
0.3948	SUB381	C(~O)(~O)
0.3722	SUB348	C(~C)(~H)(~O)(~O)
0.3410	SUB368	C(~H)(~O)(~O)
0.1185	SUB646	O=C-N-C-C
0.0747	SUB572	[#1]-C-O-[#1]
0.0537	SUB288	C-F
0.0149	SUB638	O-C-C-C-C
PF00531	Death domain
0.5931	SUB673	O=C-C=C-[#1]
PF01467	Cytidylyltransferase
0.5895	SUB660	O-C-C-N-C
0.3289	SUB392	N(~C)(~C)(~C)
0.3040	SUB398	N(~C)(:C)(:C)
0.1339	SUB625	O=C-C:C-N
0.0635	SUB457	P(-O)(=O)
PF01180	Dihydroorotate dehydrogenase
0.5891	SUB407	O(~C)(~H)
0.1822	SUB452	C(-N)(=O)
0.1608	SUB288	C-F
0.1224	SUB19	>= 1 O
0.0626	SUB375	C(~H)(~H)(~H)
0.0603	SUB309	O-H
0.0395	SUB453	C(-O)(=O)
0.0014	SUB24	>= 1 F
PF00656	Caspase domain
0.5858	SUB414	S(~C)(~H)
0.4164	SUB253	>= 1 unsaturated non-aromatic carbon-only ring size 10
0.3352	SUB543	O-C:C-[#1]
PF02807	ATP:guanido phosphotransferase, N-terminal domain
0.5843	SUB489	N-C=N-[#1]
PF07654	Immunoglobulin C1-set domain
0.5840	SUB381	C(~O)(~O)
0.3198	SUB691	O-C-C-C-C-C-O
0.2365	SUB694	O=C-C-C-C-C-O
0.2257	SUB348	C(~C)(~H)(~O)(~O)
0.1561	SUB564	O-C-O-C
0.0716	SUB618	C-C-C-O-[#1]
PF00043	Glutathione S-transferase, C-terminal domain
0.5820	SUB686	O=C-C-C-C-N
0.5187	SUB751	Nc1cc(Cl)ccc1
0.4034	SUB295	C-Cl
0.3024	SUB814	NC1CC(Cl)CCC1
0.2673	SUB369	C(~H)(~S)
0.1564	SUB350	C(~C)(~H)(~S)
0.0697	SUB200	>= 4 any ring size 6
0.0346	SUB354	C(~C)(~S)
0.0286	SUB38	>= 1 Cl
PF00202	Aminotransferase class-III
0.5811	SUB536	O=C-C-C
0.5209	SUB444	C(-C)(=O)
0.4256	SUB421	C=O
0.2805	SUB407	O(~C)(~H)
0.0089	SUB686	O=C-C-C-C-N
PF00180	Isocitrate/isopropylmalate dehydrogenase
0.5782	SUB158	>= 3 any ring size 5
0.2455	SUB664	O-C-C-O-[#1]
0.2251	SUB691	O-C-C-C-C-C-O
0.0296	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF02214	K+ channel tetramerisation domain
0.5740	SUB367	C(~H)(~O)
PF00989	PAS fold
0.5694	SUB260	>= 3 aromatic rings
0.5604	SUB549	O-C-C:C
0.4219	SUB575	O-C-C:C-C
0.2110	SUB656	O-C-C-C:C
0.1284	SUB657	C-C-N-C-C
0.0877	SUB642	O-C-C-C=C
PF00002	7 transmembrane receptor (Secretin family), 
0.5652	SUB23	>= 16 O
0.3543	SUB489	N-C=N-[#1]
PF01431	Peptidase family M13
0.5642	SUB647	O=C-N-C-[#1]
PF00349	Hexokinase
0.5618	SUB682	O-C-C-C-C-O
0.2137	SUB691	O-C-C-C-C-C-O
PF02254	TrkA-N domain
0.5580	SUB343	C(~C)(~Cl)
0.4086	SUB249	>= 1 any ring size 10
0.1022	SUB295	C-Cl
PF08070	DTHCT (NUC029),  region
0.5561	SUB249	>= 1 any ring size 10
0.1532	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
PF00337	Galactoside-binding lectin
0.5536	SUB348	C(~C)(~H)(~O)(~O)
0.0756	SUB406	O(~C)(~C)
PF01735	Lysophospholipase catalytic domain
0.5525	SUB799	CC1CC(O)CCC1
PF00400	WD domain, G-beta repeat
0.5482	SUB572	[#1]-C-O-[#1]
PF02180	Bcl-2 homology region 4
0.5470	SUB629	C-N-C-C:C
PF01770	Reduced folate carrier
0.5466	SUB369	C(~H)(~S)
PF02065	Melibiase
0.5398	SUB664	O-C-C-O-[#1]
PF00170	bZIP transcription factor
0.5362	SUB151	>= 2 any ring size 5
0.1734	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.0829	SUB200	>= 4 any ring size 6
PF00650	CRAL/TRIO domain
0.5335	SUB633	C-C-O-C:C
0.4917	SUB4	>= 32 H
0.0029	SUB621	C:C-O-C-C
PF00204	DNA gyrase B
0.5286	SUB249	>= 1 any ring size 10
0.1684	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0276	SUB186	>= 2 any ring size 6
PF00764	Arginosuccinate synthase
0.5228	SUB567	O-C-C-N
0.4017	SUB618	C-C-C-O-[#1]
PF00364	Biotin-requiring enzyme
0.5154	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.1854	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
0.1013	SUB151	>= 2 any ring size 5
PF00185	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
0.5114	SUB537	O=C-C-N
PF01916	Deoxyhypusine synthase
0.5108	SUB17	>= 4 N
PF00664	ABC transporter transmembrane region
0.5076	SUB516	N-N-C-C
0.4263	SUB519	O=C-N-N
0.3446	SUB3	>= 16 H
0.3021	SUB590	C-C:C-O-C
0.2084	SUB627	C-O-C:C-C
0.1814	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.1563	SUB699	O-C-C-C-C-C-C-C
0.1510	SUB660	O-C-C-N-C
0.0994	SUB566	C:C-O-C
0.0625	SUB466	O=S-C-C
0.0468	SUB346	C(~C)(~H)(~N)
0.0425	SUB646	O=C-N-C-C
0.0228	SUB647	O=C-N-C-[#1]
0.0002	SUB567	O-C-C-N
PF02525	Flavodoxin-like fold
0.5060	SUB342	C(~C)(~C)(~O)
0.3748	SUB398	N(~C)(:C)(:C)
0.3362	SUB554	O=C-C=C
0.2465	SUB433	C(-C)(-C)(=O)
0.2444	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.1053	SUB691	O-C-C-C-C-C-O
PF00821	Phosphoenolpyruvate carboxykinase
0.5005	SUB20	>= 2 O
0.0253	SUB505	N:C:N-C
0.0013	SUB573	N:C:N:C
PF00822	PMP-22/EMP/MP20/Claudin family
0.4909	SUB574	O-C-C=C
0.4896	SUB21	>= 4 O
0.1451	SUB620	O-C-C=C-C
PF03477	ATP cone domain
0.4899	SUB288	C-F
0.0638	SUB376	C(~N)(~N)
PF04739	5"-AMP-activated protein kinase beta subunit, interation domain
0.4896	SUB520	N=C-N-C
PF03360	Glycosyltransferase family 43
0.4884	SUB682	O-C-C-C-C-O
0.1481	SUB664	O-C-C-O-[#1]
PF01593	Flavin containing amine oxidoreductase
0.4803	SUB689	C-C-C-C-C-C-C
0.4665	SUB12	>= 8 C
0.4551	SUB357	C(~C)(:C)(:C)
0.3869	SUB431	C(-C)(-C)(=C)
0.2578	SUB394	N(~C)(~H)
0.0607	SUB593	N-C-C-C-C
PF00045	Hemopexin
0.4717	SUB533	S-C:C-[#1]
0.3813	SUB466	O=S-C-C
0.2758	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.2647	SUB515	O-N-C-C
0.2129	SUB336	C(~C)(~C)(~C)(~H)
0.1983	SUB537	O=C-C-N
0.1429	SUB444	C(-C)(=O)
0.1173	SUB354	C(~C)(~S)
0.1072	SUB375	C(~H)(~H)(~H)
0.0899	SUB492	C-N:C-[#1]
0.0583	SUB686	O=C-C-C-C-N
0.0076	SUB440	C(-C)(-N)(=O)
PF00147	Fibrinogen beta and gamma chains, C-terminal globular domain
0.4713	SUB348	C(~C)(~H)(~O)(~O)
PF00084	Sushi domain (SCR repeat), 
0.4697	SUB367	C(~H)(~O)
0.2421	SUB343	C(~C)(~Cl)
0.1009	SUB640	O-C-C-C-O
0.0834	SUB381	C(~O)(~O)
0.0242	SUB295	C-Cl
0.0084	SUB20	>= 2 O
PF01841	Transglutaminase-like superfamily
0.4523	SUB537	O=C-C-N
0.1191	SUB618	C-C-C-O-[#1]
0.1009	SUB440	C(-C)(-N)(=O)
PF02574	Homocysteine S-methyltransferase
0.4492	SUB618	C-C-C-O-[#1]
0.2683	SUB339	C(~C)(~C)(~H)(~N)
0.1841	SUB441	C(-C)(-O)(=O)
0.0197	SUB567	O-C-C-N
PF08763	Voltage gated calcium channel IQ domain
0.4483	SUB690	O-C-C-C-C-C-C
0.2134	SUB336	C(~C)(~C)(~C)(~H)
0.1979	SUB686	O=C-C-C-C-N
0.1514	SUB712	C-C(C)(C)-C-C
0.1271	SUB681	O-C-C-C-C-C
PF02737	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
0.4456	SUB389	C(:C)(:N)(:N)
0.1409	SUB360	C(~C)(:N)(:N)
0.0185	SUB32	>= 2 P
PF08718	Glycolipid transfer protein (GLTP), 
0.4416	SUB680	C-C-C-C-C-C
PF00571	CBS domain
0.4397	SUB492	C-N:C-[#1]
0.4087	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.2846	SUB441	C(-C)(-O)(=O)
0.2033	SUB453	C(-O)(=O)
0.1576	SUB618	C-C-C-O-[#1]
0.1468	SUB703	O-C-C-C-C-C-N-C
0.0848	SUB624	O=C-C:C-C
0.0503	SUB507	C-C:N:C
0.0369	SUB473	C:N:C-C
PF00175	Oxidoreductase NAD-binding domain 
0.4389	SUB622	N-C:C:C:N
0.4186	SUB419	C=N
0.2513	SUB738	Cc1cc(N)ccc1
0.2122	SUB572	[#1]-C-O-[#1]
0.1933	SUB834	NC1C(N)CCCC1
0.1386	SUB771	Nc1c(N)cccc1
0.1070	SUB376	C(~N)(~N)
0.1049	SUB602	N-C:C:C-N
0.0101	SUB340	C(~C)(~C)(~H)(~O)
0.0023	SUB407	O(~C)(~H)
PF02786	Carbamoyl-phosphate synthase L chain, ATP binding domain
0.4358	SUB441	C(-C)(-O)(=O)
0.0401	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
PF00310	Glutamine amidotransferases class-II
0.4332	SUB618	C-C-C-O-[#1]
0.3843	SUB529	[#1]-N-C-[#1]
0.3245	SUB567	O-C-C-N
0.2052	SUB341	C(~C)(~C)(~N)
PF00454	Phosphatidylinositol 3- and 4-kinase
0.4292	SUB663	O-C-C-O-C
0.1391	SUB582	O=C-C-C-O
0.0932	SUB643	O-C-C-C=O
PF02770	Acyl-CoA dehydrogenase, middle domain
0.4289	SUB32	>= 2 P
0.1359	SUB389	C(:C)(:N)(:N)
0.0785	SUB261	>= 3 hetero-aromatic rings
0.0614	SUB407	O(~C)(~H)
0.0567	SUB664	O-C-C-O-[#1]
PF01471	Putative peptidoglycan binding domain
0.4287	SUB515	O-N-C-C
0.2570	SUB492	C-N:C-[#1]
0.1799	SUB440	C(-C)(-N)(=O)
0.1781	SUB375	C(~H)(~H)(~H)
0.1614	SUB193	>= 3 any ring size 6
0.1576	SUB354	C(~C)(~S)
0.1514	SUB533	S-C:C-[#1]
0.0946	SUB444	C(-C)(=O)
0.0928	SUB537	O=C-C-N
0.0884	SUB466	O=S-C-C
0.0702	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0462	SUB336	C(~C)(~C)(~C)(~H)
0.0134	SUB686	O=C-C-C-C-N
PF00413	Matrixin
0.4265	SUB686	O=C-C-C-C-N
0.3948	SUB444	C(-C)(=O)
0.2668	SUB21	>= 4 O
0.1516	SUB698	C-C-C-C-C-C(C)-C
0.0487	SUB515	O-N-C-C
0.0441	SUB690	O-C-C-C-C-C-C
PF01035	6-O-methylguanine DNA methyltransferase, DNA binding domain
0.4252	SUB369	C(~H)(~S)
0.0148	SUB350	C(~C)(~H)(~S)
PF04961	Formiminotransferase-cyclodeaminase
0.4243	SUB686	O=C-C-C-C-N
PF00390	Malic enzyme, N-terminal domain
0.4109	SUB407	O(~C)(~H)
0.1563	SUB640	O-C-C-C-O
0.1290	SUB21	>= 4 O
PF04515	Plasma-membrane choline transporter
0.4100	SUB572	[#1]-C-O-[#1]
0.2843	SUB660	O-C-C-N-C
PF04389	Peptidase family M28
0.4090	SUB695	O=C-C-C-C-C=O
PF02771	Acyl-CoA dehydrogenase, N-terminal domain
0.4072	SUB32	>= 2 P
0.1686	SUB389	C(:C)(:N)(:N)
0.1406	SUB261	>= 3 hetero-aromatic rings
0.0129	SUB664	O-C-C-O-[#1]
0.0030	SUB407	O(~C)(~H)
PF01230	HIT domain
0.4050	SUB682	O-C-C-C-C-O
0.2273	SUB691	O-C-C-C-C-C-O
PF02800	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
0.4038	SUB158	>= 3 any ring size 5
0.0644	SUB389	C(:C)(:N)(:N)
PF00092	von Willebrand factor type A domain
0.3996	SUB441	C(-C)(-O)(=O)
0.1934	SUB708	O=C-C-C-C-C(N)-C
0.0671	SUB453	C(-O)(=O)
0.0620	SUB698	C-C-C-C-C-C(C)-C
PF00070	Pyridine nucleotide-disulphide oxidoreductase
0.3954	SUB691	O-C-C-C-C-C-O
0.2690	SUB408	O(~C)(~P)
0.0121	SUB21	>= 4 O
PF08473	Neuronal voltage-dependent calcium channel alpha 2acd
0.3950	SUB699	O-C-C-C-C-C-C-C
PF01182	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
0.3939	SUB702	O-C-C-C-C-C(O)-C
PF00704	Glycosyl hydrolases family 18
0.3923	SUB572	[#1]-C-O-[#1]
0.0786	SUB683	O-C-C-C-C-N
PF02729	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
0.3910	SUB537	O=C-C-N
PF00458	WHEP-TRS domain
0.3807	SUB537	O=C-C-N
PF03917	Eukaryotic glutathione synthase, ATP binding domain
0.3751	SUB567	O-C-C-N
PF00341	Platelet-derived growth factor (PDGF), 
0.3709	SUB713	C-C(C)-C(C)-C
0.2246	SUB640	O-C-C-C-O
PF00491	Arginase family
0.3707	SUB692	O-C-C-C-C-C-N
0.0638	SUB696	O=C-C-C-C-C-N
PF00122	E1-E2 ATPase
0.3684	SUB406	O(~C)(~C)
PF02196	Raf-like Ras-binding domain
0.3683	SUB531	N:C-C:C
0.1187	SUB675	N-C-N-C:C
0.0247	SUB492	C-N:C-[#1]
0.0232	SUB374	C(~H)(:N)
PF06387	D1 dopamine receptor-interacting protein (calcyon), 
0.3666	SUB193	>= 3 any ring size 6
0.1256	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
PF03951	Glutamine synthetase, beta-Grasp domain
0.3656	SUB695	O=C-C-C-C-C=O
PF03137	Organic Anion Transporter Polypeptide (OATP),  family
0.3642	SUB615	C-C-O-C-C
0.3280	SUB4	>= 32 H
PF00521	DNA gyrase/topoisomerase IV, subunit A
0.3632	SUB249	>= 1 any ring size 10
0.0970	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
PF00586	AIR synthase related protein, N-terminal domain
0.3621	SUB537	O=C-C-N
PF01459	Eukaryotic porin
0.3580	SUB52	>= 1 Al
0.3351	SUB313	O-Al
PF02852	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
0.3573	SUB421	C=O
0.3025	SUB21	>= 4 O
0.0889	SUB345	C(~C)(~H)
PF08441	Integrin alpha
0.3541	SUB4	>= 32 H
0.2436	SUB627	C-O-C:C-C
0.1813	SUB590	C-C:C-O-C
0.1475	SUB566	C:C-O-C
PF01596	O-methyltransferase
0.3531	SUB762	Oc1c(O)cccc1
0.2317	SUB825	OC1C(O)CCCC1
0.1084	SUB632	O-C:C-O-[#1]
PF00169	PH domain
0.3496	SUB572	[#1]-C-O-[#1]
0.3353	SUB682	O-C-C-C-C-O
0.3080	SUB408	O(~C)(~P)
0.0568	SUB407	O(~C)(~H)
0.0008	SUB32	>= 2 P
PF00976	Corticotropin ACTH domain
0.3456	SUB712	C-C(C)(C)-C-C
0.0205	SUB335	C(~C)(~C)(~C)(~C)
PF02219	Methylenetetrahydrofolate reductase
0.3441	SUB708	O=C-C-C-C-C(N)-C
0.3401	SUB674	O=C-C=C-N
PF01842	ACT domain
0.3409	SUB664	O-C-C-O-[#1]
PF08336	Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
0.3384	SUB346	C(~C)(~H)(~N)
0.2403	SUB366	C(~H)(~N)
0.0102	SUB345	C(~C)(~H)
PF05649	Peptidase family M13
0.3383	SUB647	O=C-N-C-[#1]
0.0152	SUB441	C(-C)(-O)(=O)
PF01477	PLAT/LH2 domain
0.3376	SUB699	O-C-C-C-C-C-C-C
0.1916	SUB499	O-C=C-C
0.1516	SUB375	C(~H)(~H)(~H)
0.0668	SUB646	O=C-N-C-C
0.0090	SUB382	C(~O)(:C)
PF00645	Poly(ADP-ribose),  polymerase and DNA-Ligase Zn-finger region
0.3359	SUB624	O=C-C:C-C
0.2774	SUB540	N=C-C-[#1]
0.1344	SUB598	O=C-C-C:C
PF02008	CXXC zinc finger domain
0.3320	SUB394	N(~C)(~H)
PF00927	Transglutaminase family, C-terminal ig like domain
0.3308	SUB618	C-C-C-O-[#1]
0.2234	SUB440	C(-C)(-N)(=O)
0.1273	SUB692	O-C-C-C-C-C-N
PF00217	ATP:guanido phosphotransferase, C-terminal catalytic domain
0.3302	SUB489	N-C=N-[#1]
PF01582	TIR domain
0.3297	SUB252	>= 1 saturated or aromatic heteroatom-containing ring size 10
0.2235	SUB386	C(:C)(:C)(:C)
0.0157	SUB251	>= 1 saturated or aromatic nitrogen-containing ring size 10
PF00112	Papain family cysteine protease
0.3291	SUB339	C(~C)(~C)(~H)(~N)
0.2835	SUB529	[#1]-N-C-[#1]
PF01234	NNMT/PNMT/TEMT family
0.3287	SUB629	C-N-C-C:C
PF00441	Acyl-CoA dehydrogenase, C-terminal domain
0.3250	SUB389	C(:C)(:N)(:N)
0.2136	SUB32	>= 2 P
0.0270	SUB407	O(~C)(~H)
0.0001	SUB664	O-C-C-O-[#1]
PF01687	Riboflavin kinase
0.3192	SUB548	N-C:C-N
PF01030	Receptor L domain
0.3178	SUB735	Cc1cc(C)ccc1
0.1386	SUB621	C:C-O-C-C
0.0840	SUB380	C(~N)(:N)
0.0625	SUB633	C-C-O-C:C
0.0502	SUB390	C(:N)(:N)
0.0282	SUB505	N:C:N-C
0.0193	SUB615	C-C-O-C-C
PF01055	Glycosyl hydrolases family 31 
0.3149	SUB702	O-C-C-C-C-C(O)-C
0.0927	SUB639	O-C-C-C-N
PF00018	SH3 domain
0.3142	SUB193	>= 3 any ring size 6
0.2774	SUB715	Cc1ccc(O)cc1
0.2576	SUB259	>= 2 hetero-aromatic rings
0.2529	SUB644	[#1]-C-C-N-[#1]
0.2065	SUB315	O-P
0.1349	SUB457	P(-O)(=O)
0.1313	SUB426	P=O
0.1260	SUB494	O=C-C:C
0.1183	SUB339	C(~C)(~C)(~H)(~N)
0.1021	SUB31	>= 1 P
0.0435	SUB261	>= 3 hetero-aromatic rings
0.0424	SUB412	P(~O)(~O)
0.0395	SUB622	N-C:C:C:N
0.0084	SUB608	N-C-C-C:C
PF02100	Ornithine decarboxylase antizyme
0.3141	SUB696	O=C-C-C-C-C-N
PF02772	S-adenosylmethionine synthetase, central domain
0.3141	SUB587	C-S-C-C-C
PF01336	OB-fold nucleic acid binding domain
0.3114	SUB687	O=C-C-C-C-O
0.1258	SUB688	O=C-C-C-C=O
0.0926	SUB339	C(~C)(~C)(~H)(~N)
PF00145	C-5 cytosine-specific DNA methylase
0.3110	SUB572	[#1]-C-O-[#1]
0.1504	SUB287	C-O
PF00757	Furin-like cysteine rich region
0.3087	SUB633	C-C-O-C:C
0.2713	SUB622	N-C:C:C:N
0.1569	SUB735	Cc1cc(C)ccc1
0.0814	SUB621	C:C-O-C-C
0.0619	SUB390	C(:N)(:N)
0.0196	SUB573	N:C:N:C
0.0109	SUB380	C(~N)(:N)
PF02769	AIR synthase related protein, C-terminal domain
0.3087	SUB537	O=C-C-N
PF00088	Trefoil (P-type),  domain
0.3029	SUB639	O-C-C-C-N
0.1820	SUB702	O-C-C-C-C-C(O)-C
PF00361	NADH-Ubiquinone/plastoquinone (complex I), , various chains
0.3029	SUB32	>= 2 P
0.2640	SUB389	C(:C)(:N)(:N)
PF08702	Fibrinogen alpha/beta chain family
0.3025	SUB348	C(~C)(~H)(~O)(~O)
PF08384	Pro-opiomelanocortin, N-terminal region
0.3002	SUB335	C(~C)(~C)(~C)(~C)
0.2830	SUB712	C-C(C)(C)-C-C
0.1293	SUB338	C(~C)(~C)(~C)(~O)
PF00868	Transglutaminase family
0.2973	SUB440	C(-C)(-N)(=O)
0.0882	SUB618	C-C-C-O-[#1]
0.0052	SUB692	O-C-C-C-C-C-N
PF00224	Pyruvate kinase, barrel domain
0.2969	SUB381	C(~O)(~O)
0.1538	SUB538	O=C-C-O
PF00271	Helicase conserved C-terminal domain
0.2917	SUB582	O=C-C-C-O
0.1358	SUB643	O-C-C-C=O
PF00120	Glutamine synthetase, catalytic domain
0.2851	SUB695	O=C-C-C-C-C=O
PF00702	haloacid dehalogenase-like hydrolase
0.2725	SUB634	N-C-C:C-C
0.2622	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.2427	SUB620	O-C-C=C-C
0.2290	SUB574	O-C-C=C
0.0570	SUB496	C-N-C:C
0.0568	SUB25	>= 2 F
0.0378	SUB629	C-N-C-C:C
0.0343	SUB375	C(~H)(~H)(~H)
0.0101	SUB703	O-C-C-C-C-C-N-C
PF02142	MGS-like domain
0.2662	SUB537	O=C-C-N
0.0803	SUB674	O=C-C=C-N
PF00278	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
0.2661	SUB498	O-C:C:N
0.1897	SUB692	O-C-C-C-C-C-N
PF00206	Lyase
0.2619	SUB488	N-C=N-C
PF01262	Alanine dehydrogenase/PNT, C-terminal domain
0.2617	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.1172	SUB691	O-C-C-C-C-C-O
0.0884	SUB21	>= 4 O
PF01808	AICARFT/IMPCHase bienzyme
0.2607	SUB674	O=C-C=C-N
PF01433	Peptidase family M1
0.2606	SUB441	C(-C)(-O)(=O)
0.0667	SUB453	C(-O)(=O)
PF02812	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
0.2591	SUB683	O-C-C-C-C-N
PF02544	3-oxo-5-alpha-steroid 4-dehydrogenase 
0.2352	SUB801	CC1CC(N)CCC1
0.1699	SUB145	>= 1 saturated or aromatic carbon-only ring size 5
0.0896	SUB243	>= 1 saturated or aromatic carbon-only ring size 9
0.0607	SUB705	O=C-C-C-C-C-C-C
0.0416	SUB861	CC1C(C)CCC1
PF01179	Copper amine oxidase, enzyme domain
0.2332	SUB394	N(~C)(~H)
PF01571	Aminomethyltransferase folate-binding domain
0.2322	SUB708	O=C-C-C-C-C(N)-C
0.2025	SUB691	O-C-C-C-C-C-O
PF08246	Cathepsin propeptide inhibitor domain (I29), 
0.2274	SUB612	N-C-C-N-C
0.0453	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
PF00328	Histidine acid phosphatase
0.2260	SUB664	O-C-C-O-[#1]
PF00151	Lipase
0.2160	SUB441	C(-C)(-O)(=O)
PF02784	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
0.2156	SUB498	O-C:C:N
0.0218	SUB692	O-C-C-C-C-C-N
PF00027	Cyclic nucleotide-binding domain
0.2145	SUB340	C(~C)(~C)(~H)(~O)
0.1996	SUB549	O-C-C:C
0.1543	SUB575	O-C-C:C-C
0.1006	SUB656	O-C-C-C:C
PF00670	S-adenosyl-L-homocysteine hydrolase, NAD binding domain
0.2079	SUB572	[#1]-C-O-[#1]
PF05222	Alanine dehydrogenase/PNT, N-terminal domain
0.2061	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.0597	SUB691	O-C-C-C-C-C-O
PF03949	Malic enzyme, NAD binding domain
0.2044	SUB21	>= 4 O
0.1545	SUB664	O-C-C-O-[#1]
0.1097	SUB407	O(~C)(~H)
0.0096	SUB640	O-C-C-C-O
PF03727	Hexokinase
0.2024	SUB691	O-C-C-C-C-C-O
PF02773	S-adenosylmethionine synthetase, C-terminal domain
0.2007	SUB413	S(~C)(~C)
0.1599	SUB587	C-S-C-C-C
PF07973	Threonyl and Alanyl tRNA synthetase second additional domain
0.1966	SUB537	O=C-C-N
PF00258	Flavodoxin
0.1874	SUB339	C(~C)(~C)(~H)(~N)
0.1720	SUB375	C(~H)(~H)(~H)
PF00614	Phospholipase D Active site motif
0.1869	SUB660	O-C-C-N-C
PF01712	Deoxynucleoside kinase
0.1843	SUB613	N-C-O-C-C
0.0760	SUB664	O-C-C-O-[#1]
0.0627	SUB691	O-C-C-C-C-C-O
PF00342	Phosphoglucose isomerase
0.1815	SUB572	[#1]-C-O-[#1]
PF03068	Protein-arginine deiminase (PAD), 
0.1734	SUB703	O-C-C-C-C-C-N-C
PF02161	Progesterone receptor
0.1730	SUB338	C(~C)(~C)(~C)(~O)
PF02785	Biotin carboxylase C-terminal domain
0.1676	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
PF02743	Cache domain
0.1645	SUB699	O-C-C-C-C-C-C-C
PF06464	DMAP1-binding Domain
0.1582	SUB300	N-H
0.0647	SUB394	N(~C)(~H)
PF08526	Protein-arginine deiminase (PAD),  N-terminal domain
0.1536	SUB703	O-C-C-C-C-C-N-C
PF01564	Spermine/spermidine synthase
0.1468	SUB594	N-C-C-C-N
PF00452	Apoptosis regulator proteins, Bcl-2 family
0.1462	SUB629	C-N-C-C:C
PF01426	BAH domain
0.1461	SUB300	N-H
0.0189	SUB394	N(~C)(~H)
PF00152	tRNA synthetases class II (D, K and N),  
0.1429	SUB688	O=C-C-C-C=O
0.1117	SUB537	O=C-C-N
0.0011	SUB339	C(~C)(~C)(~H)(~N)
PF01082	Copper type II ascorbate-dependent monooxygenase, N-terminal domain
0.1419	SUB664	O-C-C-O-[#1]
PF00490	Delta-aminolevulinic acid dehydratase
0.1365	SUB696	O=C-C-C-C-C-N
PF00667	FAD binding domain
0.1247	SUB375	C(~H)(~H)(~H)
0.0200	SUB339	C(~C)(~C)(~H)(~N)
PF00432	Prenyltransferase and squalene oxidase repeat
0.1137	SUB697	C-C-C-C-C-C-C-C
PF01536	Adenosylmethionine decarboxylase
0.1119	SUB644	[#1]-C-C-N-[#1]
PF06021	Aralkyl acyl-CoA:amino acid N-acyltransferase
0.1099	SUB537	O=C-C-N
0.0508	SUB441	C(-C)(-O)(=O)
PF08669	Glycine cleavage T-protein C-terminal barrel domain
0.1085	SUB708	O=C-C-C-C-C(N)-C
0.1005	SUB674	O=C-C=C-N
PF00479	Glucose-6-phosphate dehydrogenase, NAD binding domain
0.1080	SUB664	O-C-C-O-[#1]
PF00357	Integrin alpha cytoplasmic region
0.1067	SUB200	>= 4 any ring size 6
PF00173	Cytochrome b5-like Heme/Steroid binding domain
0.1016	SUB375	C(~H)(~H)(~H)
0.0016	SUB441	C(-C)(-O)(=O)
PF00438	S-adenosylmethionine synthetase, N-terminal domain
0.0995	SUB587	C-S-C-C-C
PF00044	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
0.0994	SUB389	C(:C)(:N)(:N)
0.0455	SUB158	>= 3 any ring size 5
PF02728	Copper amine oxidase, N3 domain
0.0945	SUB394	N(~C)(~H)
PF02155	Glucocorticoid receptor
0.0869	SUB841	CC1CC(O)CC1
0.0796	SUB862	CC1C(O)CCC1
0.0440	SUB243	>= 1 saturated or aromatic carbon-only ring size 9
0.0163	SUB618	C-C-C-O-[#1]
0.0115	SUB840	CC1CC(C)CC1
0.0093	SUB861	CC1C(C)CCC1
0.0083	SUB145	>= 1 saturated or aromatic carbon-only ring size 5
PF02867	Ribonucleotide reductase, barrel domain
0.0864	SUB376	C(~N)(~N)
PF08035	Opioids neuropeptide
0.0808	SUB712	C-C(C)(C)-C-C
0.0731	SUB335	C(~C)(~C)(~C)(~C)
PF00003	7 transmembrane sweet-taste receptor of 3 GCPR
0.0703	SUB529	[#1]-N-C-[#1]
PF00749	tRNA synthetases class I (E and Q), , catalytic domain
0.0691	SUB695	O=C-C-C-C-C=O
PF02727	Copper amine oxidase, N2 domain
0.0662	SUB394	N(~C)(~H)
PF05221	S-adenosyl-L-homocysteine hydrolase
0.0597	SUB572	[#1]-C-O-[#1]
PF08444	Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
0.0539	SUB537	O=C-C-N
0.0140	SUB441	C(-C)(-O)(=O)
PF00317	Ribonucleotide reductase, all-alpha domain
0.0531	SUB376	C(~N)(~N)
PF03199	Eukaryotic glutathione synthase
0.0448	SUB567	O-C-C-N
PF08399	VWA N-terminal
0.0403	SUB699	O-C-C-C-C-C-C-C
PF02887	Pyruvate kinase, alpha/beta domain
0.0398	SUB381	C(~O)(~O)
PF03765	CRAL/TRIO, N-terminus
0.0351	SUB633	C-C-O-C:C
0.0268	SUB4	>= 32 H
0.0047	SUB621	C:C-O-C-C
PF00431	CUB domain
0.0316	SUB337	C(~C)(~C)(~C)(~N)
PF00289	Carbamoyl-phosphate synthase L chain, N-terminal domain
0.0212	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
PF00214	Calcitonin / CGRP / IAPP family
0.0193	SUB704	O-C-C-C-C-C(N)-C
PF00487	Fatty acid desaturase
0.0156	SUB441	C(-C)(-O)(=O)
PF05995	Cysteine dioxygenase type I
0.0100	SUB567	O-C-C-N
PF02870	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
0.0093	SUB350	C(~C)(~H)(~S)
0.0002	SUB369	C(~H)(~S)
PF07837	Formiminotransferase domain, N-terminal subdomain
0.0091	SUB686	O=C-C-C-C-N
PF02781	Glucose-6-phosphate dehydrogenase, C-terminal domain
0.0041	SUB664	O-C-C-O-[#1]
PF00931	NB-ARC domain
0.0012	SUB572	[#1]-C-O-[#1]
PF02971	Formiminotransferase domain
PF01406	tRNA synthetases class I (C),  catalytic domain
PF00025	ADP-ribosylation factor family