PF01126	Heme oxygenase
1.5792	SUB158	>= 3 any ring size 5
PF00042	Globin
1.5630	SUB387	C(:C)(:C)(:N)
0.1028	SUB700	O-C-C-C-C-C(C)-C
0.0421	SUB251	>= 1 saturated or aromatic nitrogen-containing ring size 10
0.0132	SUB540	N=C-C-[#1]
PF00191	Annexin
1.3732	SUB840	CC1CC(C)CC1
0.2857	SUB572	[#1]-C-O-[#1]
0.1610	SUB253	>= 1 unsaturated non-aromatic carbon-only ring size 10
PF01124	MAPEG family
1.2767	SUB414	S(~C)(~H)
0.0493	SUB686	O=C-C-C-C-N
0.0222	SUB695	O=C-C-C-C-C=O
0.0137	SUB696	O=C-C-C-C-C-N
PF00025	ADP-ribosylation factor family
1.2402	SUB32	>= 2 P
PF01370	NAD dependent epimerase/dehydratase family
1.1032	SUB32	>= 2 P
0.3720	SUB664	O-C-C-O-[#1]
0.2457	SUB392	N(~C)(~C)(~C)
0.1049	SUB572	[#1]-C-O-[#1]
0.0303	SUB10	>= 2 C
PF00020	TNFR/NGFR cysteine-rich region
1.0937	SUB190	>= 2 unsaturated non-aromatic carbon-only ring size 6
PF00001	7 transmembrane receptor (rhodopsin family), 
1.0861	SUB410	O(:C)(:C)
0.7574	SUB330	C(~Br)(~H)
0.5810	SUB841	CC1CC(O)CC1
0.5352	SUB201	>= 4 saturated or aromatic carbon-only ring size 6
0.5282	SUB359	C(~C)(:N)
0.5037	SUB588	N-C:C-O-[#1]
0.4996	SUB707	O=C-C-C-C-C(=O)-C
0.4730	SUB736	Cc1cc(O)ccc1
0.4708	SUB815	NC1CC(Br)CCC1
0.4615	SUB409	O(~H)(~S)
0.4507	SUB792	NC1CCC(N)CC1
0.4350	SUB256	>= 1 aromatic ring
0.4310	SUB606	O=C-C-O-C
0.4301	SUB862	CC1C(O)CCC1
0.4137	SUB352	C(~C)(~N)
0.4029	SUB406	O(~C)(~C)
0.3680	SUB757	Cc1c(O)cccc1
0.3671	SUB451	C(-N)(=N)
0.3652	SUB638	O-C-C-C-C
0.3643	SUB675	N-C-N-C:C
0.3592	SUB3	>= 16 H
0.3549	SUB835	NC1C(Cl)CCCC1
0.3537	SUB180	>= 1 saturated or aromatic carbon-only ring size 6
0.3503	SUB356	C(~C)(:C)
0.3440	SUB659	C-C-S-C-C
0.3006	SUB388	C(:C)(:N)
0.2981	SUB35	>= 2 S
0.2966	SUB800	CC1CC(S)CCC1
0.2944	SUB684	N-C-C-C-C-C
0.2928	SUB167	>= 4 saturated or aromatic nitrogen-containing ring size 5
0.2871	SUB442	C(-C)(=C)
0.2841	SUB44	>= 1 Br
0.2829	SUB441	C(-C)(-O)(=O)
0.2758	SUB421	C=O
0.2717	SUB340	C(~C)(~C)(~H)(~O)
0.2581	SUB436	C(-C)(-H)(=N)
0.2580	SUB392	N(~C)(~C)(~C)
0.2553	SUB710	C-C(C)-C-C-C
0.2472	SUB300	N-H
0.2443	SUB523	C-N-N-[#1]
0.2413	SUB656	O-C-C-C:C
0.2409	SUB712	C-C(C)(C)-C-C
0.2386	SUB217	>= 1 saturated or aromatic heteroatom-containing ring size 7
0.2383	SUB608	N-C-C-C:C
0.2379	SUB518	N-N-C-N
0.2365	SUB653	O-C:C:C-N
0.2333	SUB600	[#1]-C-C=C-[#1]
0.2287	SUB338	C(~C)(~C)(~C)(~O)
0.2282	SUB387	C(:C)(:C)(:N)
0.2249	SUB643	O-C-C-C=O
0.2199	SUB386	C(:C)(:C)(:C)
0.2162	SUB629	C-N-C-C:C
0.2078	SUB685	O=C-C-C-C-C
0.2066	SUB360	C(~C)(:N)(:N)
0.2012	SUB677	N#C-C-C-C
0.1962	SUB529	[#1]-N-C-[#1]
0.1947	SUB668	C=C-C-O-[#1]
0.1947	SUB651	O=C-N-C=O
0.1826	SUB193	>= 3 any ring size 6
0.1825	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.1751	SUB560	O-C-N-[#1]
0.1749	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.1714	SUB780	CC1CCC(N)CC1
0.1703	SUB625	O=C-C:C-N
0.1699	SUB375	C(~H)(~H)(~H)
0.1686	SUB394	N(~C)(~H)
0.1638	SUB534	S-C:C-N
0.1610	SUB189	>= 2 saturated or aromatic heteroatom-containing ring size 6
0.1594	SUB658	C-N-C:C-C
0.1569	SUB773	Nc1c(Br)cccc1
0.1555	SUB435	C(-C)(-H)(=C)
0.1545	SUB620	O-C-C=C-C
0.1460	SUB494	O=C-C:C
0.1452	SUB444	C(-C)(=O)
0.1337	SUB630	S-C:C:C-N
0.1317	SUB13	>= 16 C
0.1314	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.1241	SUB821	CC1C(S)CCCC1
0.1240	SUB25	>= 2 F
0.1234	SUB346	C(~C)(~H)(~N)
0.1199	SUB147	>= 1 saturated or aromatic heteroatom-containing ring size 5
0.1184	SUB820	CC1C(O)CCCC1
0.1155	SUB648	O=C-N-C-N
0.1131	SUB572	[#1]-C-O-[#1]
0.1118	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
0.1092	SUB12	>= 8 C
0.1087	SUB582	O=C-C-C-O
0.1014	SUB718	Cc1ccc(Cl)cc1
0.1013	SUB688	O=C-C-C-C=O
0.0999	SUB804	OC1CC(O)CCC1
0.0999	SUB692	O-C-C-C-C-C-N
0.0988	SUB575	O-C-C:C-C
0.0987	SUB697	C-C-C-C-C-C-C-C
0.0973	SUB840	CC1CC(C)CC1
0.0963	SUB759	Cc1c(N)cccc1
0.0954	SUB586	C-C:C-N-C
0.0931	SUB660	O-C-C-N-C
0.0897	SUB762	Oc1c(O)cccc1
0.0895	SUB825	OC1C(O)CCCC1
0.0863	SUB673	O=C-C=C-[#1]
0.0812	SUB556	N=C-C=C
0.0754	SUB372	C(~H)(:C)(:C)
0.0740	SUB535	S-C:C-O
0.0739	SUB763	Oc1c(S)cccc1
0.0732	SUB834	NC1C(N)CCCC1
0.0730	SUB481	C:S:C-C
0.0729	SUB417	C=C
0.0716	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.0713	SUB765	Oc1c(Cl)cccc1
0.0695	SUB528	C:C:N-[#1]
0.0695	SUB613	N-C-O-C-C
0.0666	SUB543	O-C:C-[#1]
0.0622	SUB231	>= 1 saturated or aromatic heteroatom-containing ring size 8
0.0574	SUB548	N-C:C-N
0.0573	SUB621	C:C-O-C-C
0.0570	SUB801	CC1CC(N)CCC1
0.0551	SUB715	Cc1ccc(O)cc1
0.0541	SUB689	C-C-C-C-C-C-C
0.0531	SUB144	>= 1 any ring size 5
0.0522	SUB371	C(~H)(:C)
0.0518	SUB632	O-C:C-O-[#1]
0.0497	SUB190	>= 2 unsaturated non-aromatic carbon-only ring size 6
0.0492	SUB633	C-C-O-C:C
0.0458	SUB401	N(~H)(:C)(:C)
0.0420	SUB399	N(~H)(~N)
0.0413	SUB596	C:C-C-C-C
0.0397	SUB419	C=N
0.0389	SUB446	C(-H)(-N)(=C)
0.0380	SUB252	>= 1 saturated or aromatic heteroatom-containing ring size 10
0.0358	SUB381	C(~O)(~O)
0.0347	SUB337	C(~C)(~C)(~C)(~N)
0.0336	SUB506	Cl-C:C-O
0.0324	SUB17	>= 4 N
0.0297	SUB663	O-C-C-O-C
0.0287	SUB14	>= 32 C
0.0281	SUB536	O=C-C-C
0.0238	SUB422	C=S
0.0233	SUB570	N-C-C-N
0.0228	SUB639	O-C-C-C-N
0.0226	SUB646	O=C-N-C-C
0.0219	SUB462	O-C-C=N
0.0199	SUB657	C-C-N-C-C
0.0196	SUB215	>= 1 saturated or aromatic carbon-only ring size 7
0.0192	SUB682	O-C-C-C-C-O
0.0188	SUB611	C-O-C-O-C
0.0177	SUB200	>= 4 any ring size 6
0.0135	SUB609	C-C-C-C:C
0.0125	SUB597	N=C-N-C-C
0.0104	SUB655	N-C-N-C-C
0.0099	SUB752	Nc1cc(Br)ccc1
0.0089	SUB21	>= 4 O
0.0089	SUB654	O-C:C:C-O
0.0083	SUB601	N-C:C:C-C
0.0061	SUB18	>= 8 N
0.0060	SUB391	N(~C)(~C)
0.0052	SUB540	N=C-C-[#1]
0.0048	SUB610	Cl-C-C-N-C
0.0020	SUB614	C-N-C-C-C
0.0011	SUB547	N-C:C-[#1]
0.0008	SUB576	O-C-C:C-O
0.0007	SUB259	>= 2 hetero-aromatic rings
0.0002	SUB295	C-Cl
0.0001	SUB175	>= 5 saturated or aromatic heteroatom-containing ring size 5
0.0001	SUB373	C(~H)(:C)(:N)
0.0001	SUB20	>= 2 O
0.0001	SUB499	O-C=C-C
PF00069	Protein kinase domain
1.0802	SUB670	Cl-C:C-C=O
1.0525	SUB503	N-C=C-[#1]
0.7734	SUB506	Cl-C:C-O
0.6964	SUB499	O-C=C-C
0.6759	SUB140	>= 2 saturated or aromatic heteroatom-containing ring size 4
0.6701	SUB216	>= 1 saturated or aromatic nitrogen-containing ring size 7
0.6183	SUB190	>= 2 unsaturated non-aromatic carbon-only ring size 6
0.5928	SUB408	O(~C)(~P)
0.5642	SUB365	C(~F)(:C)
0.5320	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.4312	SUB602	N-C:C:C-N
0.4094	SUB451	C(-N)(=N)
0.3844	SUB151	>= 2 any ring size 5
0.3785	SUB672	O=C-C=C-C
0.3732	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.3473	SUB517	[#1]-C=C-[#1]
0.3267	SUB454	N(-C)(=C)
0.3241	SUB200	>= 4 any ring size 6
0.2896	SUB640	O-C-C-C-O
0.2896	SUB384	C(~S)(:C)
0.2825	SUB703	O-C-C-C-C-C-N-C
0.2500	SUB5	>= 1 Li
0.2390	SUB367	C(~H)(~O)
0.2350	SUB432	C(-C)(-C)(=N)
0.2346	SUB726	Sc1ccc(N)cc1
0.2329	SUB572	[#1]-C-O-[#1]
0.2298	SUB137	>= 2 any ring size 4
0.2221	SUB642	O-C-C-C=C
0.2217	SUB700	O-C-C-C-C-C(C)-C
0.2096	SUB591	C-C:C-O-[#1]
0.1942	SUB760	Cc1c(Cl)cccc1
0.1894	SUB632	O-C:C-O-[#1]
0.1772	SUB686	O=C-C-C-C-N
0.1766	SUB565	C=C-C=C
0.1679	SUB617	C:C:N:N:C
0.1626	SUB594	N-C-C-C-N
0.1618	SUB380	C(~N)(:N)
0.1581	SUB580	O=C-C-C-C
0.1513	SUB33	>= 4 P
0.1503	SUB372	C(~H)(:C)(:C)
0.1499	SUB393	N(~C)(~C)(~H)
0.1478	SUB369	C(~H)(~S)
0.1374	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.1209	SUB300	N-H
0.1205	SUB117	>= 1 saturated or aromatic carbon-only ring size 3
0.1168	SUB242	>= 1 any ring size 9
0.1145	SUB431	C(-C)(-C)(=C)
0.1051	SUB789	SC1CCC(N)CC1
0.1043	SUB674	O=C-C=C-N
0.0868	SUB259	>= 2 hetero-aromatic rings
0.0841	SUB529	[#1]-N-C-[#1]
0.0836	SUB675	N-C-N-C:C
0.0826	SUB411	P(~C)(~C)
0.0789	SUB522	C:N-C-[#1]
0.0750	SUB735	Cc1cc(C)ccc1
0.0685	SUB629	C-N-C-C:C
0.0648	SUB379	C(~N)(:C)(:N)
0.0645	SUB258	>= 2 aromatic rings
0.0583	SUB186	>= 2 any ring size 6
0.0567	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.0538	SUB806	OC1CC(N)CCC1
0.0448	SUB249	>= 1 any ring size 10
0.0442	SUB144	>= 1 any ring size 5
0.0436	SUB32	>= 2 P
0.0391	SUB342	C(~C)(~C)(~O)
0.0350	SUB324	P-H
0.0341	SUB683	O-C-C-C-C-N
0.0318	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0292	SUB654	O-C:C:C-O
0.0266	SUB2	>= 8 H
0.0199	SUB644	[#1]-C-C-N-[#1]
0.0198	SUB488	N-C=N-C
0.0159	SUB374	C(~H)(:N)
0.0146	SUB710	C-C(C)-C-C-C
0.0135	SUB551	Cl-C-C-C
0.0002	SUB95	>= 1 Au
PF12497	Estrogen receptor beta
1.0793	SUB778	CC1CCC(O)CC1
0.2722	SUB350	C(~C)(~H)(~S)
0.1393	SUB369	C(~H)(~S)
0.1257	SUB413	S(~C)(~C)
0.0985	SUB508	C-C-S-C
0.0597	SUB258	>= 2 aromatic rings
0.0284	SUB587	C-S-C-C-C
PF01391	Collagen triple helix repeat (20 copies), 
1.0608	SUB706	O=C-C-C-C-C(O)-C
0.2747	SUB702	O-C-C-C-C-C(O)-C
PF01916	Deoxyhypusine synthase
1.0413	SUB17	>= 4 N
PF00167	Fibroblast growth factor
1.0341	SUB409	O(~H)(~S)
0.2712	SUB34	>= 1 S
0.2408	SUB572	[#1]-C-O-[#1]
0.1750	SUB368	C(~H)(~O)(~O)
0.1467	SUB309	O-H
PF00497	Bacterial extracellular solute-binding proteins, family 3
1.0209	SUB656	O-C-C-C:C
0.8707	SUB337	C(~C)(~C)(~C)(~N)
0.4584	SUB286	C-N
0.2095	SUB354	C(~C)(~S)
0.1292	SUB366	C(~H)(~N)
0.1156	SUB453	C(-O)(=O)
0.0360	SUB392	N(~C)(~C)(~C)
0.0092	SUB713	C-C(C)-C(C)-C
0.0070	SUB1	>= 4 H
0.0047	SUB712	C-C(C)(C)-C-C
PF00255	Glutathione peroxidase
1.0204	SUB414	S(~C)(~H)
0.1913	SUB686	O=C-C-C-C-N
0.1862	SUB695	O=C-C-C-C-C=O
0.1526	SUB694	O=C-C-C-C-C-O
0.1050	SUB703	O-C-C-C-C-C-N-C
0.0272	SUB660	O-C-C-N-C
PF00334	Nucleoside diphosphate kinase
1.0178	SUB32	>= 2 P
PF01735	Lysophospholipase catalytic domain
1.0170	SUB840	CC1CC(C)CC1
0.0255	SUB799	CC1CC(O)CCC1
PF05761	5" nucleotidase family
1.0113	SUB360	C(~C)(:N)(:N)
PF09396	Thrombin light chain
1.0006	SUB193	>= 3 any ring size 6
PF00654	Voltage gated chloride channel
1.0005	SUB364	C(~F)(~F)
PF00214	Calcitonin / CGRP / IAPP family
0.9958	SUB704	O-C-C-C-C-C(N)-C
0.0681	SUB703	O-C-C-C-C-C-N-C
0.0561	SUB393	N(~C)(~C)(~H)
0.0410	SUB743	Oc1cc(N)ccc1
0.0169	SUB612	N-C-C-N-C
0.0031	SUB529	[#1]-N-C-[#1]
PF07562	Nine Cysteines Domain of family 3 GPCR
0.9904	SUB657	C-C-N-C-C
0.3729	SUB339	C(~C)(~C)(~H)(~N)
0.2530	SUB21	>= 4 O
0.0271	SUB409	O(~H)(~S)
PF08403	Amino acid permease N-terminal
0.9790	SUB38	>= 1 Cl
0.1657	SUB484	N-S-C:C
0.1654	SUB655	N-C-N-C-C
0.1422	SUB466	O=S-C-C
0.1361	SUB533	S-C:C-[#1]
0.1041	SUB561	N-C-N-C
0.0276	SUB415	S(~C)(~O)
0.0102	SUB598	O=C-C-C:C
0.0080	SUB554	O=C-C=C
0.0003	SUB494	O=C-C:C
0.0002	SUB624	O=C-C:C-C
PF01053	Cys/Met metabolism PLP-dependent enzyme
0.9686	SUB498	O-C:C:N
0.5000	SUB414	S(~C)(~H)
PF00375	Sodium:dicarboxylate symporter family
0.9578	SUB537	O=C-C-N
0.1960	SUB339	C(~C)(~C)(~H)(~N)
0.0982	SUB686	O=C-C-C-C-N
0.0341	SUB567	O-C-C-N
0.0304	SUB683	O-C-C-C-C-N
PF00656	Caspase domain
0.9464	SUB253	>= 1 unsaturated non-aromatic carbon-only ring size 10
0.7094	SUB414	S(~C)(~H)
0.3870	SUB543	O-C:C-[#1]
0.3348	SUB647	O=C-N-C-[#1]
0.2874	SUB354	C(~C)(~S)
0.2115	SUB722	Oc1ccc(N)cc1
0.1286	SUB401	N(~H)(:C)(:C)
0.0904	SUB576	O-C-C:C-O
0.0125	SUB785	OC1CCC(N)CC1
0.0092	SUB582	O=C-C-C-O
0.0001	SUB643	O-C-C-C=O
PF01770	Reduced folate carrier
0.9424	SUB369	C(~H)(~S)
0.0462	SUB475	S:C:C:N
0.0177	SUB398	N(~C)(:C)(:C)
PF01429	Methyl-CpG binding domain
0.9382	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
PF03171	2OG-Fe(II),  oxygenase superfamily
0.9277	SUB687	O=C-C-C-C-O
0.2296	SUB603	O=C-C-N-C
0.1818	SUB144	>= 1 any ring size 5
0.1603	SUB684	N-C-C-C-C-C
0.1491	SUB439	C(-C)(-N)(=N)
0.1272	SUB583	C-C-C-C-C
0.0893	SUB580	O=C-C-C-C
0.0680	SUB606	O=C-C-O-C
0.0541	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.0478	SUB556	N=C-C=C
0.0339	SUB564	O-C-O-C
0.0219	SUB662	O-C-O-C-C
0.0002	SUB333	C(~C)(~C)
PF00587	tRNA synthetase class II core domain (G, H, P, S and T), 
0.9255	SUB537	O=C-C-N
0.0216	SUB339	C(~C)(~C)(~H)(~N)
PF00079	Serpin (serine protease inhibitor), 
0.9235	SUB720	Oc1ccc(O)cc1
0.8729	SUB706	O=C-C-C-C-C(O)-C
0.4571	SUB407	O(~C)(~H)
0.3789	SUB682	O-C-C-C-C-O
0.3609	SUB516	N-N-C-C
0.3209	SUB440	C(-C)(-N)(=O)
0.2538	SUB537	O=C-C-N
0.2471	SUB713	C-C(C)-C(C)-C
0.2397	SUB144	>= 1 any ring size 5
0.2232	SUB369	C(~H)(~S)
0.1616	SUB301	N-N
0.1609	SUB703	O-C-C-C-C-C-N-C
0.1559	SUB368	C(~H)(~O)(~O)
0.1345	SUB1	>= 4 H
0.1318	SUB362	C(~Cl)(~H)
0.1314	SUB640	O-C-C-C-O
0.1191	SUB621	C:C-O-C-C
0.1021	SUB778	CC1CCC(O)CC1
0.0961	SUB361	C(~Cl)(~Cl)
0.0951	SUB258	>= 2 aromatic rings
0.0904	SUB344	C(~C)(~Cl)(~H)
0.0861	SUB823	CC1C(Cl)CCCC1
0.0761	SUB615	C-C-O-C-C
0.0760	SUB618	C-C-C-O-[#1]
0.0690	SUB646	O=C-N-C-C
0.0566	SUB572	[#1]-C-O-[#1]
0.0512	SUB697	C-C-C-C-C-C-C-C
0.0468	SUB348	C(~C)(~H)(~O)(~O)
0.0440	SUB567	O-C-C-N
0.0427	SUB431	C(-C)(-C)(=C)
0.0295	SUB633	C-C-O-C:C
0.0249	SUB696	O=C-C-C-C-C-N
0.0128	SUB35	>= 2 S
0.0023	SUB299	C-I
0.0001	SUB351	C(~C)(~I)
PF00348	Polyprenyl synthetase
0.8892	SUB32	>= 2 P
0.1765	SUB293	C-P
PF00462	Glutaredoxin
0.8825	SUB414	S(~C)(~H)
0.1674	SUB695	O=C-C-C-C-C=O
0.0459	SUB694	O=C-C-C-C-C-O
PF00128	Alpha amylase, catalytic domain
0.8717	SUB339	C(~C)(~C)(~H)(~N)
0.1000	SUB381	C(~O)(~O)
0.0731	SUB618	C-C-C-O-[#1]
0.0153	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
PF02798	Glutathione S-transferase, N-terminal domain
0.8648	SUB686	O=C-C-C-C-N
0.4363	SUB350	C(~C)(~H)(~S)
0.3365	SUB694	O=C-C-C-C-C-O
0.2043	SUB63	>= 1 Zn
0.1899	SUB744	Oc1cc(Cl)ccc1
0.1754	SUB339	C(~C)(~C)(~H)(~N)
0.1673	SUB580	O=C-C-C-C
0.1120	SUB756	Cc1c(C)cccc1
0.0688	SUB603	O=C-C-N-C
0.0443	SUB709	C-C(C)-C-C
0.0399	SUB612	N-C-C-N-C
0.0083	SUB570	N-C-C-N
0.0037	SUB597	N=C-N-C-C
0.0002	SUB670	Cl-C:C-C=O
PF06374	NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2), 
0.8648	SUB387	C(:C)(:C)(:N)
0.3457	SUB261	>= 3 hetero-aromatic rings
0.0644	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0013	SUB703	O-C-C-C-C-C-N-C
PF01039	Carboxyl transferase domain
0.8538	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
0.1747	SUB339	C(~C)(~C)(~H)(~N)
0.0813	SUB336	C(~C)(~C)(~C)(~H)
PF00625	Guanylate kinase
0.8494	SUB4	>= 32 H
0.4791	SUB51	>= 1 Mg
0.2513	SUB20	>= 2 O
0.2456	SUB392	N(~C)(~C)(~C)
0.2446	SUB430	C(#N)(-C)
0.1012	SUB656	O-C-C-C:C
0.0284	SUB663	O-C-C-O-C
0.0196	SUB460	S(=O)(=O)
0.0044	SUB569	N#C-C-C
PF00102	Protein-tyrosine phosphatase
0.8485	SUB309	O-H
0.3169	SUB668	C=C-C-O-[#1]
0.2038	SUB603	O=C-C-N-C
0.2005	SUB621	C:C-O-C-C
0.1849	SUB293	C-P
0.1765	SUB532	S-C:C-C
0.1505	SUB1	>= 4 H
0.1495	SUB593	N-C-C-C-C
0.1416	SUB537	O=C-C-N
0.1328	SUB633	C-C-O-C:C
0.0883	SUB494	O=C-C:C
0.0851	SUB667	C=C-C-O-C
0.0632	SUB595	C-O-C-C=C
0.0569	SUB4	>= 32 H
0.0276	SUB345	C(~C)(~H)
0.0249	SUB697	C-C-C-C-C-C-C-C
0.0120	SUB463	O-C-C=O
0.0081	SUB605	C-O-C-C:C
0.0066	SUB541	C-N-C-[#1]
0.0044	SUB575	O-C-C:C-C
0.0027	SUB384	C(~S)(:C)
0.0008	SUB538	O=C-C-O
PF00464	Serine hydroxymethyltransferase
0.8426	SUB567	O-C-C-N
0.5915	SUB554	O=C-C=C
0.3129	SUB686	O=C-C-C-C-N
0.1115	SUB624	O=C-C:C-C
0.0654	SUB454	N(-C)(=C)
0.0571	SUB674	O=C-C=C-N
0.0290	SUB346	C(~C)(~H)(~N)
0.0155	SUB708	O=C-C-C-C-C(N)-C
PF02668	Taurine catabolism dioxygenase TauD, TfdA family
0.8365	SUB687	O=C-C-C-C-O
PF00459	Inositol monophosphatase family
0.8333	SUB5	>= 1 Li
0.5636	SUB783	OC1CCC(O)CC1
0.2173	SUB408	O(~C)(~P)
0.1729	SUB804	OC1CC(O)CCC1
PF00143	Interferon alpha/beta domain
0.8333	SUB348	C(~C)(~H)(~O)(~O)
PF07645	Calcium-binding EGF domain
0.8284	SUB172	>= 5 any ring size 5
0.5630	SUB422	C=S
0.4836	SUB756	Cc1c(C)cccc1
0.2988	SUB393	N(~C)(~C)(~H)
0.2091	SUB406	O(~C)(~C)
0.1288	SUB501	C-S-C:C
0.1077	SUB685	O=C-C-C-C-C
0.0940	SUB702	O-C-C-C-C-C(O)-C
0.0280	SUB696	O=C-C-C-C-C-N
0.0204	SUB348	C(~C)(~H)(~O)(~O)
0.0201	SUB368	C(~H)(~O)(~O)
0.0103	SUB375	C(~H)(~H)(~H)
PF08718	Glycolipid transfer protein (GLTP), 
0.8000	SUB680	C-C-C-C-C-C
PF00071	Ras family
0.7968	SUB190	>= 2 unsaturated non-aromatic carbon-only ring size 6
0.7195	SUB246	>= 1 unsaturated non-aromatic carbon-only ring size 9
0.6570	SUB398	N(~C)(:C)(:C)
0.3815	SUB494	O=C-C:C
0.3400	SUB625	O=C-C:C-N
0.2666	SUB706	O=C-C-C-C-C(O)-C
0.1999	SUB536	O=C-C-C
0.1432	SUB618	C-C-C-O-[#1]
0.1079	SUB441	C(-C)(-O)(=O)
0.0683	SUB365	C(~F)(:C)
0.0612	SUB32	>= 2 P
0.0189	SUB148	>= 1 unsaturated non-aromatic carbon-only ring size 5
0.0125	SUB242	>= 1 any ring size 9
0.0096	SUB495	O=C-C:N
0.0081	SUB703	O-C-C-C-C-C-N-C
0.0058	SUB642	O-C-C-C=C
PF02525	Flavodoxin-like fold
0.7906	SUB398	N(~C)(:C)(:C)
0.2950	SUB431	C(-C)(-C)(=C)
0.1795	SUB200	>= 4 any ring size 6
0.1752	SUB554	O=C-C=C
0.1746	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.1329	SUB433	C(-C)(-C)(=O)
0.1298	SUB342	C(~C)(~C)(~O)
0.1222	SUB691	O-C-C-C-C-C-O
PF00194	Eukaryotic-type carbonic anhydrase
0.7896	SUB306	N-S
0.7279	SUB16	>= 2 N
0.6224	SUB96	>= 1 Hg
0.3863	SUB677	N#C-C-C-C
0.2972	SUB453	C(-O)(=O)
0.2742	SUB353	C(~C)(~O)
0.2003	SUB484	N-S-C:C
0.1865	SUB284	C-H
0.1534	SUB287	C-O
0.1521	SUB438	C(-C)(-N)(=C)
0.1242	SUB20	>= 2 O
0.1190	SUB716	Cc1ccc(S)cc1
0.1086	SUB429	C(#C)(-H)
0.0774	SUB657	C-C-N-C-C
0.0446	SUB346	C(~C)(~H)(~N)
0.0375	SUB746	Sc1cc(S)ccc1
0.0358	SUB461	C-C-C#C
0.0307	SUB363	C(~Cl)(:C)
0.0270	SUB428	C(#C)(-C)
0.0259	SUB809	SC1CC(S)CCC1
0.0245	SUB502	Cl-C:C-C
0.0231	SUB541	C-N-C-[#1]
0.0132	SUB599	Cl-C:C:C-C
0.0122	SUB336	C(~C)(~C)(~C)(~H)
0.0073	SUB420	C#N
0.0064	SUB19	>= 1 O
0.0030	SUB673	O=C-C=C-[#1]
0.0022	SUB504	Cl-C:C-[#1]
PF00709	Adenylosuccinate synthetase
0.7886	SUB529	[#1]-N-C-[#1]
0.0462	SUB639	O-C-C-C-N
0.0265	SUB341	C(~C)(~C)(~N)
0.0214	SUB688	O=C-C-C-C=O
PF00023	Ankyrin repeat
0.7884	SUB681	O-C-C-C-C-C
0.4507	SUB686	O=C-C-C-C-N
0.2694	SUB339	C(~C)(~C)(~H)(~N)
0.1776	SUB261	>= 3 hetero-aromatic rings
0.1486	SUB622	N-C:C:C:N
0.1192	SUB697	C-C-C-C-C-C-C-C
0.1050	SUB602	N-C:C:C-N
0.0886	SUB517	[#1]-C=C-[#1]
0.0816	SUB695	O=C-C-C-C-C=O
0.0659	SUB694	O=C-C-C-C-C-O
0.0479	SUB820	CC1C(O)CCCC1
0.0448	SUB616	N-C-C-O-C
0.0322	SUB688	O=C-C-C-C=O
0.0159	SUB683	O-C-C-C-C-N
0.0156	SUB16	>= 2 N
0.0044	SUB3	>= 16 H
PF00728	Glycosyl hydrolase family 20, catalytic domain
0.7878	SUB664	O-C-C-O-[#1]
PF00551	Formyl transferase
0.7876	SUB695	O=C-C-C-C-C=O
0.3141	SUB691	O-C-C-C-C-C-O
0.2182	SUB660	O-C-C-N-C
0.1760	SUB647	O=C-N-C-[#1]
PF00229	TNF(Tumour Necrosis Factor),  family 
0.7850	SUB706	O=C-C-C-C-C(O)-C
0.4715	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.4566	SUB694	O=C-C-C-C-C-O
0.4404	SUB688	O=C-C-C-C=O
0.4354	SUB550	N-C-C:C
0.3746	SUB378	C(~N)(:C)(:C)
0.3252	SUB691	O-C-C-C-C-C-O
0.1945	SUB347	C(~C)(~H)(~O)
0.1398	SUB393	N(~C)(~C)(~H)
0.1270	SUB673	O=C-C=C-[#1]
0.0959	SUB337	C(~C)(~C)(~C)(~N)
0.0938	SUB502	Cl-C:C-C
0.0881	SUB249	>= 1 any ring size 10
0.0617	SUB711	C-C-C(C)-C-C
0.0538	SUB363	C(~Cl)(:C)
0.0380	SUB592	Cl-C-C-C-C
0.0292	SUB599	Cl-C:C:C-C
0.0139	SUB359	C(~C)(:N)
0.0120	SUB504	Cl-C:C-[#1]
PF00248	Aldo/keto reductase family
0.7846	SUB629	C-N-C-C:C
0.4940	SUB334	C(~C)(~C)(~C)
0.3866	SUB567	O-C-C-N
0.3835	SUB537	O=C-C-N
0.3365	SUB23	>= 16 O
0.3161	SUB32	>= 2 P
0.2936	SUB369	C(~H)(~S)
0.2879	SUB691	O-C-C-C-C-C-O
0.2439	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.2386	SUB24	>= 1 F
0.1794	SUB296	C-As
0.1678	SUB284	C-H
0.1581	SUB444	C(-C)(=O)
0.1576	SUB381	C(~O)(~O)
0.1519	SUB1	>= 4 H
0.1420	SUB713	C-C(C)-C(C)-C
0.1142	SUB288	C-F
0.1086	SUB294	C-S
0.1046	SUB412	P(~O)(~O)
0.0719	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0710	SUB389	C(:C)(:N)(:N)
0.0709	SUB685	O=C-C-C-C-C
0.0670	SUB340	C(~C)(~C)(~H)(~O)
0.0486	SUB407	O(~C)(~H)
0.0420	SUB710	C-C(C)-C-C-C
0.0343	SUB250	>= 1 saturated or aromatic carbon-only ring size 10
0.0313	SUB421	C=O
0.0304	SUB13	>= 16 C
0.0112	SUB633	C-C-O-C:C
0.0103	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0049	SUB621	C:C-O-C-C
0.0014	SUB408	O(~C)(~P)
0.0009	SUB66	>= 1 As
PF00211	Adenylate and Guanylate cyclase catalytic domain
0.7804	SUB424	N=O
0.4631	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.3366	SUB703	O-C-C-C-C-C-N-C
0.1401	SUB17	>= 4 N
0.0717	SUB613	N-C-O-C-C
0.0679	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
PF00233	3"5"-cyclic nucleotide phosphodiesterase
0.7802	SUB703	O-C-C-C-C-C-N-C
0.5561	SUB252	>= 1 saturated or aromatic heteroatom-containing ring size 10
0.5316	SUB356	C(~C)(:C)
0.4348	SUB711	C-C-C(C)-C-C
0.3980	SUB144	>= 1 any ring size 5
0.3856	SUB369	C(~H)(~S)
0.3800	SUB645	C-C=N-N-C
0.3718	SUB353	C(~C)(~O)
0.3536	SUB351	C(~C)(~I)
0.3092	SUB631	O-C:C-O-C
0.2843	SUB597	N=C-N-C-C
0.2625	SUB299	C-I
0.2492	SUB419	C=N
0.2383	SUB536	O=C-C-C
0.2372	SUB537	O=C-C-N
0.2356	SUB145	>= 1 saturated or aromatic carbon-only ring size 5
0.1627	SUB443	C(-C)(=N)
0.1614	SUB517	[#1]-C=C-[#1]
0.1449	SUB572	[#1]-C-O-[#1]
0.1443	SUB347	C(~C)(~H)(~O)
0.1351	SUB705	O=C-C-C-C-C-C-C
0.1290	SUB578	C:C-N-C:C
0.1195	SUB151	>= 2 any ring size 5
0.1056	SUB452	C(-N)(=O)
0.1024	SUB152	>= 2 saturated or aromatic carbon-only ring size 5
0.1016	SUB554	O=C-C=C
0.1002	SUB612	N-C-C-N-C
0.0945	SUB13	>= 16 C
0.0764	SUB35	>= 2 S
0.0719	SUB633	C-C-O-C:C
0.0546	SUB342	C(~C)(~C)(~O)
0.0519	SUB533	S-C:C-[#1]
0.0483	SUB454	N(-C)(=C)
0.0471	SUB433	C(-C)(-C)(=O)
0.0433	SUB500	N-C:C:N
0.0294	SUB256	>= 1 aromatic ring
0.0161	SUB657	C-C-N-C-C
0.0064	SUB621	C:C-O-C-C
0.0060	SUB486	N:C:C:N
0.0017	SUB421	C=O
PF02806	Alpha amylase, C-terminal all-beta domain
0.7753	SUB691	O-C-C-C-C-C-O
0.0131	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.0064	SUB664	O-C-C-O-[#1]
0.0005	SUB572	[#1]-C-O-[#1]
PF00068	Phospholipase A2
0.7736	SUB722	Oc1ccc(N)cc1
0.4114	SUB440	C(-C)(-N)(=O)
0.2624	SUB686	O=C-C-C-C-N
0.2427	SUB4	>= 32 H
0.1577	SUB638	O-C-C-C-C
0.0617	SUB338	C(~C)(~C)(~C)(~O)
0.0499	SUB640	O-C-C-C-O
0.0396	SUB260	>= 3 aromatic rings
0.0364	SUB683	O-C-C-C-C-N
PF00186	Dihydrofolate reductase
0.7597	SUB17	>= 4 N
0.6473	SUB379	C(~N)(:C)(:N)
0.4533	SUB413	S(~C)(~C)
0.3485	SUB394	N(~C)(~H)
0.1336	SUB415	S(~C)(~O)
0.0277	SUB458	S(-C)(=O)
0.0070	SUB339	C(~C)(~C)(~H)(~N)
PF01007	Inward rectifier potassium channel
0.7500	SUB330	C(~Br)(~H)
0.6430	SUB306	N-S
0.5692	SUB336	C(~C)(~C)(~C)(~H)
0.4225	SUB614	C-N-C-C-C
0.3952	SUB376	C(~N)(~N)
0.3026	SUB450	C(-N)(=C)
0.2619	SUB697	C-C-C-C-C-C-C-C
0.2575	SUB626	O=C-C:C-O
0.2420	SUB440	C(-C)(-N)(=O)
0.2406	SUB430	C(#N)(-C)
0.2352	SUB186	>= 2 any ring size 6
0.1762	SUB566	C:C-O-C
0.1539	SUB452	C(-N)(=O)
0.1464	SUB458	S(-C)(=O)
0.1151	SUB657	C-C-N-C-C
0.0588	SUB415	S(~C)(~O)
0.0454	SUB392	N(~C)(~C)(~C)
0.0409	SUB569	N#C-C-C
0.0404	SUB647	O=C-N-C-[#1]
0.0245	SUB4	>= 32 H
0.0150	SUB420	C#N
0.0069	SUB503	N-C=C-[#1]
0.0063	SUB435	C(-C)(-H)(=C)
PF01406	tRNA synthetases class I (C),  catalytic domain
0.7500	SUB414	S(~C)(~H)
PF01160	Vertebrate endogenous opioids neuropeptide
0.7468	SUB208	>= 5 saturated or aromatic carbon-only ring size 6
0.1744	SUB201	>= 4 saturated or aromatic carbon-only ring size 6
0.1621	SUB117	>= 1 saturated or aromatic carbon-only ring size 3
PF08240	Alcohol dehydrogenase GroES-like domain
0.7438	SUB695	O=C-C-C-C-C=O
0.5828	SUB622	N-C:C:C:N
0.4806	SUB158	>= 3 any ring size 5
0.4123	SUB407	O(~C)(~H)
0.3266	SUB66	>= 1 As
0.1710	SUB446	C(-H)(-N)(=C)
0.1019	SUB572	[#1]-C-O-[#1]
0.1007	SUB360	C(~C)(:N)(:N)
0.0297	SUB421	C=O
0.0278	SUB577	N=C-C:C-[#1]
0.0010	SUB296	C-As
PF00133	tRNA synthetases class I (I, L, M and V), 
0.7429	SUB336	C(~C)(~C)(~C)(~H)
0.1800	SUB339	C(~C)(~C)(~H)(~N)
PF00106	short chain dehydrogenase
0.7374	SUB389	C(:C)(:N)(:N)
0.5480	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.5350	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.4580	SUB158	>= 3 any ring size 5
0.4353	SUB580	O=C-C-C-C
0.3973	SUB698	C-C-C-C-C-C(C)-C
0.3274	SUB577	N=C-C:C-[#1]
0.3031	SUB674	O=C-C=C-N
0.2945	SUB21	>= 4 O
0.2270	SUB261	>= 3 hetero-aromatic rings
0.2212	SUB712	C-C(C)(C)-C-C
0.2111	SUB683	O-C-C-C-C-N
0.1998	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.1915	SUB309	O-H
0.1760	SUB179	>= 1 any ring size 6
0.1541	SUB688	O=C-C-C-C=O
0.1451	SUB407	O(~C)(~H)
0.1395	SUB360	C(~C)(:N)(:N)
0.1264	SUB335	C(~C)(~C)(~C)(~C)
0.1108	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0998	SUB668	C=C-C-O-[#1]
0.0981	SUB622	N-C:C:C:N
0.0845	SUB13	>= 16 C
0.0825	SUB3	>= 16 H
0.0506	SUB602	N-C:C:C-N
0.0504	SUB186	>= 2 any ring size 6
0.0496	SUB615	C-C-O-C-C
0.0386	SUB617	C:C:N:N:C
0.0018	SUB243	>= 1 saturated or aromatic carbon-only ring size 9
PF00048	Small cytokines (intecrine/chemokine), , interleukin-8 like
0.7307	SUB702	O-C-C-C-C-C(O)-C
0.6983	SUB309	O-H
0.6044	SUB642	O-C-C-C=C
0.5286	SUB694	O=C-C-C-C-C-O
0.3778	SUB441	C(-C)(-O)(=O)
0.3626	SUB340	C(~C)(~C)(~H)(~O)
0.2638	SUB673	O=C-C=C-[#1]
0.2199	SUB396	N(~C)(~O)
0.1979	SUB862	CC1C(O)CCC1
0.1873	SUB336	C(~C)(~C)(~C)(~H)
0.1755	SUB499	O-C=C-C
0.1488	SUB674	O=C-C=C-N
0.1472	SUB593	N-C-C-C-C
0.1270	SUB375	C(~H)(~H)(~H)
0.1004	SUB515	O-N-C-C
0.0969	SUB346	C(~C)(~H)(~N)
0.0688	SUB459	S(-O)(=O)
0.0572	SUB554	O=C-C=C
0.0160	SUB706	O=C-C-C-C-C(O)-C
0.0141	SUB34	>= 1 S
0.0005	SUB302	N-O
PF00107	Zinc-binding dehydrogenase
0.7302	SUB449	C(-H)(=O)
0.4506	SUB421	C=O
0.3190	SUB367	C(~H)(~O)
0.2134	SUB681	O-C-C-C-C-C
0.1754	SUB284	C-H
0.1261	SUB373	C(~H)(:C)(:N)
0.0911	SUB622	N-C:C:C:N
0.0698	SUB1	>= 4 H
0.0468	SUB452	C(-N)(=O)
0.0450	SUB446	C(-H)(-N)(=C)
0.0256	SUB517	[#1]-C=C-[#1]
0.0059	SUB66	>= 1 As
0.0006	SUB296	C-As
PF02919	Eukaryotic DNA topoisomerase I, DNA binding fragment
0.7300	SUB252	>= 1 saturated or aromatic heteroatom-containing ring size 10
0.6082	SUB759	Cc1c(N)cccc1
0.3519	SUB664	O-C-C-O-[#1]
0.1462	SUB463	O-C-C=O
0.1075	SUB538	O=C-C-O
0.1030	SUB582	O=C-C-C-O
0.0725	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0156	SUB643	O-C-C-C=O
PF00303	Thymidylate synthase
0.7294	SUB407	O(~C)(~H)
0.6793	SUB674	O=C-C=C-N
0.1460	SUB647	O=C-N-C-[#1]
0.0474	SUB376	C(~N)(~N)
0.0145	SUB572	[#1]-C-O-[#1]
PF00557	Metallopeptidase family M24
0.7260	SUB338	C(~C)(~C)(~C)(~O)
0.4684	SUB567	O-C-C-N
0.2459	SUB463	O-C-C=O
0.1427	SUB538	O=C-C-O
0.1023	SUB339	C(~C)(~C)(~H)(~N)
0.0968	SUB375	C(~H)(~H)(~H)
0.0840	SUB350	C(~C)(~H)(~S)
0.0725	SUB444	C(-C)(=O)
0.0101	SUB407	O(~C)(~H)
PF00067	Cytochrome P450
0.7182	SUB398	N(~C)(:C)(:C)
0.5959	SUB727	Sc1ccc(Cl)cc1
0.5340	SUB623	O=C-O-C:C
0.4850	SUB503	N-C=C-[#1]
0.4633	SUB39	>= 2 Cl
0.4624	SUB158	>= 3 any ring size 5
0.4406	SUB186	>= 2 any ring size 6
0.3754	SUB660	O-C-C-N-C
0.3275	SUB706	O=C-C-C-C-C(O)-C
0.3113	SUB257	>= 1 hetero-aromatic ring
0.2890	SUB695	O=C-C-C-C-C=O
0.2541	SUB17	>= 4 N
0.2257	SUB13	>= 16 C
0.2078	SUB144	>= 1 any ring size 5
0.2043	SUB616	N-C-C-O-C
0.2017	SUB249	>= 1 any ring size 10
0.1794	SUB594	N-C-C-C-N
0.1682	SUB504	Cl-C:C-[#1]
0.1614	SUB378	C(~N)(:C)(:C)
0.1597	SUB3	>= 16 H
0.1397	SUB681	O-C-C-C-C-C
0.1229	SUB353	C(~C)(~O)
0.1130	SUB335	C(~C)(~C)(~C)(~C)
0.1128	SUB580	O=C-C-C-C
0.1049	SUB522	C:N-C-[#1]
0.0977	SUB713	C-C(C)-C(C)-C
0.0756	SUB431	C(-C)(-C)(=C)
0.0731	SUB259	>= 2 hetero-aromatic rings
0.0649	SUB242	>= 1 any ring size 9
0.0628	SUB435	C(-C)(-H)(=C)
0.0590	SUB404	N(:C)(:C)
0.0436	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0427	SUB12	>= 8 C
0.0401	SUB14	>= 32 C
0.0391	SUB486	N:C:C:N
0.0311	SUB780	CC1CCC(N)CC1
0.0269	SUB381	C(~O)(~O)
0.0261	SUB637	C-N-C-N-C
0.0200	SUB250	>= 1 saturated or aromatic carbon-only ring size 10
0.0193	SUB447	C(-H)(=C)
0.0170	SUB505	N:C:N-C
0.0138	SUB573	N:C:N:C
0.0072	SUB662	O-C-O-C-C
0.0045	SUB564	O-C-O-C
0.0002	SUB790	SC1CCC(Cl)CC1
PF02823	ATP synthase, Delta/Epsilon chain, beta-sandwich domain
0.7152	SUB364	C(~F)(~F)
0.2045	SUB25	>= 2 F
PF00324	Amino acid permease
0.7149	SUB441	C(-C)(-O)(=O)
0.6738	SUB42	>= 1 K
0.5997	SUB484	N-S-C:C
0.3206	SUB738	Cc1cc(N)ccc1
0.3094	SUB644	[#1]-C-C-N-[#1]
0.2386	SUB16	>= 2 N
0.2012	SUB38	>= 1 Cl
0.1691	SUB339	C(~C)(~C)(~H)(~N)
0.1154	SUB694	O=C-C-C-C-C-O
0.1133	SUB529	[#1]-N-C-[#1]
0.0839	SUB681	O-C-C-C-C-C
0.0513	SUB567	O-C-C-N
0.0367	SUB801	CC1CC(N)CCC1
0.0327	SUB35	>= 2 S
0.0098	SUB341	C(~C)(~C)(~N)
PF02155	Glucocorticoid receptor
0.7131	SUB618	C-C-C-O-[#1]
0.0258	SUB347	C(~C)(~H)(~O)
PF07654	Immunoglobulin C1-set domain
0.7130	SUB694	O=C-C-C-C-C-O
0.4085	SUB348	C(~C)(~H)(~O)(~O)
0.3035	SUB691	O-C-C-C-C-C-O
0.2054	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.1816	SUB381	C(~O)(~O)
0.1134	SUB683	O-C-C-C-C-N
0.1051	SUB695	O=C-C-C-C-C=O
0.0980	SUB640	O-C-C-C-O
0.0904	SUB615	C-C-O-C-C
0.0798	SUB564	O-C-O-C
0.0360	SUB662	O-C-O-C-C
PF00854	POT family
0.7125	SUB133	>= 1 saturated or aromatic heteroatom-containing ring size 4
0.5642	SUB132	>= 1 saturated or aromatic nitrogen-containing ring size 4
0.3924	SUB130	>= 1 any ring size 4
PF01532	Glycosyl hydrolase family 47
0.7104	SUB682	O-C-C-C-C-O
0.0899	SUB618	C-C-C-O-[#1]
PF00225	Kinesin motor domain
0.7083	SUB629	C-N-C-C:C
0.3499	SUB683	O-C-C-C-C-N
0.3152	SUB637	C-N-C-N-C
0.2399	SUB407	O(~C)(~H)
0.2218	SUB736	Cc1cc(O)ccc1
0.2052	SUB20	>= 2 O
0.0853	SUB591	C-C:C-O-[#1]
0.0272	SUB799	CC1CC(O)CCC1
0.0001	SUB655	N-C-N-C-C
PF00074	Pancreatic ribonuclease
0.7061	SUB360	C(~C)(:N)(:N)
0.5513	SUB694	O=C-C-C-C-C-O
0.3795	SUB412	P(~O)(~O)
0.3647	SUB646	O=C-N-C-C
0.3101	SUB444	C(-C)(=O)
0.2684	SUB644	[#1]-C-C-N-[#1]
0.2360	SUB260	>= 3 aromatic rings
0.1026	SUB426	P=O
0.0889	SUB31	>= 1 P
0.0760	SUB32	>= 2 P
0.0654	SUB441	C(-C)(-O)(=O)
0.0223	SUB457	P(-O)(=O)
0.0143	SUB408	O(~C)(~P)
0.0008	SUB453	C(-O)(=O)
PF01048	Phosphorylase superfamily
0.7051	SUB242	>= 1 any ring size 9
0.3171	SUB520	N=C-N-C
0.2029	SUB597	N=C-N-C-C
0.1498	SUB451	C(-N)(=N)
0.0282	SUB572	[#1]-C-O-[#1]
0.0252	SUB488	N-C=N-C
0.0058	SUB400	N(~H)(:C)
0.0040	SUB528	C:C:N-[#1]
0.0029	SUB151	>= 2 any ring size 5
PF00305	Lipoxygenase
0.7030	SUB515	O-N-C-C
0.3537	SUB759	Cc1c(N)cccc1
0.2416	SUB179	>= 1 any ring size 6
0.2415	SUB640	O-C-C-C-O
0.2397	SUB375	C(~H)(~H)(~H)
0.1483	SUB799	CC1CC(O)CCC1
0.1432	SUB672	O=C-C=C-C
0.0589	SUB386	C(:C)(:C)(:C)
0.0076	SUB378	C(~N)(:C)(:C)
PF02423	Ornithine cyclodeaminase/mu-crystallin family
0.6963	SUB49	>= 4 I
PF00755	Choline/Carnitine o-acyltransferase
0.6909	SUB541	C-N-C-[#1]
0.4655	SUB686	O=C-C-C-C-N
0.1762	SUB660	O-C-C-N-C
0.0527	SUB614	C-N-C-C-C
0.0330	SUB336	C(~C)(~C)(~C)(~H)
0.0063	SUB391	N(~C)(~C)
PF07884	Vitamin K epoxide reductase family
0.6893	SUB433	C(-C)(-C)(=O)
0.1738	SUB673	O=C-C=C-[#1]
0.0518	SUB598	O=C-C-C:C
PF02267	ADP-ribosyl cyclase
0.6875	SUB448	C(-H)(=N)
0.1875	SUB613	N-C-O-C-C
PF03477	ATP cone domain
0.6788	SUB288	C-F
0.0955	SUB376	C(~N)(~N)
0.0479	SUB24	>= 1 F
PF03062	MBOAT family
0.6786	SUB706	O=C-C-C-C-C(O)-C
0.2978	SUB715	Cc1ccc(O)cc1
0.0382	SUB340	C(~C)(~C)(~H)(~O)
PF01180	Dihydroorotate dehydrogenase
0.6757	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.2768	SUB19	>= 1 O
0.2314	SUB646	O=C-N-C-C
0.2182	SUB24	>= 1 F
0.1667	SUB407	O(~C)(~H)
0.1393	SUB453	C(-O)(=O)
0.1207	SUB375	C(~H)(~H)(~H)
0.0716	SUB396	N(~C)(~O)
0.0642	SUB515	O-N-C-C
0.0567	SUB288	C-F
0.0346	SUB655	N-C-N-C-C
0.0040	SUB302	N-O
PF00175	Oxidoreductase NAD-binding domain 
0.6742	SUB622	N-C:C:C:N
0.2824	SUB738	Cc1cc(N)ccc1
0.2195	SUB682	O-C-C-C-C-O
0.1627	SUB703	O-C-C-C-C-C-N-C
0.1252	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1105	SUB340	C(~C)(~C)(~H)(~O)
0.1092	SUB17	>= 4 N
0.1057	SUB638	O-C-C-C-C
0.0926	SUB431	C(-C)(-C)(=C)
0.0852	SUB561	N-C-N-C
0.0787	SUB407	O(~C)(~H)
0.0740	SUB717	Cc1ccc(N)cc1
0.0660	SUB771	Nc1c(N)cccc1
0.0462	SUB536	O=C-C-C
0.0416	SUB158	>= 3 any ring size 5
PF00903	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
0.6708	SUB695	O=C-C-C-C-C=O
0.3191	SUB350	C(~C)(~H)(~S)
0.2240	SUB369	C(~H)(~S)
0.1446	SUB515	O-N-C-C
0.0618	SUB696	O=C-C-C-C-C-N
0.0004	SUB402	N(~O)(~O)
0.0002	SUB456	N(-O)(=O)
PF00209	Sodium:neurotransmitter symporter family
0.6700	SUB519	O=C-N-N
0.5755	SUB346	C(~C)(~H)(~N)
0.4749	SUB692	O-C-C-C-C-C-N
0.3936	SUB662	O-C-O-C-C
0.2857	SUB180	>= 1 saturated or aromatic carbon-only ring size 6
0.2647	SUB579	C-C:C-C:C
0.2409	SUB394	N(~C)(~H)
0.2124	SUB697	C-C-C-C-C-C-C-C
0.1993	SUB518	N-N-C-N
0.1646	SUB608	N-C-C-C:C
0.1566	SUB160	>= 3 saturated or aromatic nitrogen-containing ring size 5
0.1520	SUB780	CC1CCC(N)CC1
0.1336	SUB392	N(~C)(~C)(~C)
0.1197	SUB353	C(~C)(~O)
0.1160	SUB657	C-C-N-C-C
0.1156	SUB644	[#1]-C-C-N-[#1]
0.1005	SUB369	C(~H)(~S)
0.0937	SUB736	Cc1cc(O)ccc1
0.0927	SUB756	Cc1c(C)cccc1
0.0843	SUB751	Nc1cc(Cl)ccc1
0.0703	SUB381	C(~O)(~O)
0.0658	SUB541	C-N-C-[#1]
0.0509	SUB564	O-C-O-C
0.0424	SUB520	N=C-N-C
0.0404	SUB814	NC1CC(Cl)CCC1
0.0274	SUB214	>= 1 any ring size 7
0.0261	SUB616	N-C-C-O-C
0.0180	SUB144	>= 1 any ring size 5
0.0104	SUB799	CC1CC(O)CCC1
0.0091	SUB698	C-C-C-C-C-C(C)-C
0.0059	SUB660	O-C-C-N-C
0.0038	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0024	SUB158	>= 3 any ring size 5
0.0003	SUB604	C-C:C:C-C
PF02223	Thymidylate kinase
0.6653	SUB613	N-C-O-C-C
0.2621	SUB703	O-C-C-C-C-C-N-C
PF07690	Major Facilitator Superfamily
0.6620	SUB536	O=C-C-C
0.6534	SUB631	O-C:C-O-C
0.4095	SUB339	C(~C)(~C)(~H)(~N)
0.2933	SUB708	O=C-C-C-C-C(N)-C
0.2660	SUB694	O=C-C-C-C-C-O
0.2646	SUB249	>= 1 any ring size 10
0.2283	SUB433	C(-C)(-C)(=O)
0.1593	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.1451	SUB686	O=C-C-C-C-N
0.1257	SUB612	N-C-C-N-C
0.0961	SUB570	N-C-C-N
0.0610	SUB495	O=C-C:N
0.0240	SUB578	C:C-N-C:C
PF00343	Carbohydrate phosphorylase
0.6548	SUB640	O-C-C-C-O
0.4767	SUB730	Nc1ccc(Cl)cc1
0.4364	SUB793	NC1CCC(Cl)CC1
0.4295	SUB578	C:C-N-C:C
0.2634	SUB408	O(~C)(~P)
0.2305	SUB710	C-C(C)-C-C-C
0.2235	SUB651	O=C-N-C=O
0.1678	SUB646	O=C-N-C-C
0.1662	SUB347	C(~C)(~H)(~O)
0.1523	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.1507	SUB682	O-C-C-C-C-O
0.1443	SUB432	C(-C)(-C)(=N)
0.1194	SUB407	O(~C)(~H)
0.0388	SUB648	O=C-N-C-N
0.0293	SUB624	O=C-C:C-C
0.0201	SUB537	O=C-C-N
0.0147	SUB179	>= 1 any ring size 6
0.0046	SUB618	C-C-C-O-[#1]
PF00227	Proteasome subunit
0.6525	SUB277	B-O
0.6357	SUB7	>= 1 B
0.4201	SUB275	B-C
PF00821	Phosphoenolpyruvate carboxykinase
0.6502	SUB20	>= 2 O
0.2693	SUB573	N:C:N:C
0.2344	SUB495	O=C-C:N
0.1804	SUB486	N:C:C:N
0.0891	SUB554	O=C-C=C
0.0598	SUB407	O(~C)(~H)
PF07686	Immunoglobulin V-set domain
0.6491	SUB414	S(~C)(~H)
0.4537	SUB578	C:C-N-C:C
0.3870	SUB340	C(~C)(~C)(~H)(~O)
0.3519	SUB647	O=C-N-C-[#1]
0.3099	SUB288	C-F
0.2718	SUB646	O=C-N-C-C
0.2485	SUB686	O=C-C-C-C-N
0.1900	SUB368	C(~H)(~O)(~O)
0.1727	SUB348	C(~C)(~H)(~O)(~O)
0.1124	SUB612	N-C-C-N-C
0.0969	SUB793	NC1CCC(Cl)CC1
0.0616	SUB760	Cc1c(Cl)cccc1
0.0599	SUB823	CC1C(Cl)CCCC1
0.0597	SUB730	Nc1ccc(Cl)cc1
0.0569	SUB341	C(~C)(~C)(~N)
0.0558	SUB673	O=C-C=C-[#1]
0.0555	SUB342	C(~C)(~C)(~O)
0.0496	SUB572	[#1]-C-O-[#1]
0.0403	SUB570	N-C-C-N
0.0360	SUB381	C(~O)(~O)
PF00939	Sodium:sulfate symporter transmembrane region
0.6489	SUB687	O=C-C-C-C-O
0.1637	SUB688	O=C-C-C-C=O
PF00341	Platelet-derived growth factor (PDGF), 
0.6441	SUB640	O-C-C-C-O
0.6289	SUB713	C-C(C)-C(C)-C
0.3868	SUB806	OC1CC(N)CCC1
0.2200	SUB340	C(~C)(~C)(~H)(~O)
0.1116	SUB706	O=C-C-C-C-C(O)-C
0.1113	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.1047	SUB231	>= 1 saturated or aromatic heteroatom-containing ring size 8
0.1021	SUB336	C(~C)(~C)(~C)(~H)
0.0804	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.0787	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
0.0542	SUB228	>= 1 any ring size 8
PF00310	Glutamine amidotransferases class-II
0.6425	SUB618	C-C-C-O-[#1]
0.1636	SUB686	O=C-C-C-C-N
0.1347	SUB341	C(~C)(~C)(~N)
0.0022	SUB695	O=C-C-C-C-C=O
PF01852	START domain
0.6415	SUB457	P(-O)(=O)
0.1028	SUB408	O(~C)(~P)
0.0057	SUB31	>= 1 P
PF00648	Calpain family cysteine protease
0.6389	SUB433	C(-C)(-C)(=O)
PF00155	Aminotransferase class I and II
0.6385	SUB567	O-C-C-N
0.6007	SUB498	O-C:C:N
0.4327	SUB588	N-C:C-O-[#1]
0.3190	SUB339	C(~C)(~C)(~H)(~N)
0.3172	SUB529	[#1]-N-C-[#1]
0.2069	SUB462	O-C-C=N
0.1490	SUB686	O=C-C-C-C-N
0.1181	SUB537	O=C-C-N
0.1164	SUB685	O=C-C-C-C-C
0.1014	SUB341	C(~C)(~C)(~N)
0.0981	SUB608	N-C-C-C:C
0.0110	SUB694	O=C-C-C-C-C-O
0.0056	SUB408	O(~C)(~P)
PF00576	HIUase/Transthyretin family
0.6377	SUB656	O-C-C-C:C
0.4283	SUB407	O(~C)(~H)
0.2240	SUB369	C(~H)(~S)
0.1602	SUB284	C-H
0.1450	SUB258	>= 2 aromatic rings
0.1096	SUB19	>= 1 O
0.0582	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0238	SUB10	>= 2 C
PF02897	Prolyl oligopeptidase, N-terminal beta-propeller domain
0.6373	SUB18	>= 8 N
0.3270	SUB35	>= 2 S
PF01536	Adenosylmethionine decarboxylase
0.6328	SUB644	[#1]-C-C-N-[#1]
0.0587	SUB640	O-C-C-C-O
PF00579	tRNA synthetases class I (W and Y), 
0.6317	SUB537	O=C-C-N
0.3176	SUB699	O-C-C-C-C-C-C-C
0.1295	SUB693	O=C-C-C-C-C-C
0.1275	SUB705	O=C-C-C-C-C-C-C
0.0896	SUB339	C(~C)(~C)(~H)(~N)
0.0624	SUB759	Cc1c(N)cccc1
0.0186	SUB697	C-C-C-C-C-C-C-C
PF08674	Acetylcholinesterase tetramerisation domain
0.6269	SUB392	N(~C)(~C)(~C)
0.3081	SUB1	>= 4 H
0.1666	SUB284	C-H
0.1154	SUB391	N(~C)(~C)
0.0355	SUB315	O-P
0.0230	SUB629	C-N-C-C:C
0.0197	SUB2	>= 8 H
0.0010	SUB426	P=O
PF00264	Common central domain of tyrosinase
0.6268	SUB536	O=C-C-C
0.0597	SUB503	N-C=C-[#1]
PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase
0.6245	SUB14	>= 32 C
0.4092	SUB568	O-C-C-O
0.2472	SUB458	S(-C)(=O)
0.2099	SUB603	O=C-C-N-C
0.1106	SUB606	O=C-C-O-C
0.1077	SUB413	S(~C)(~C)
0.0748	SUB572	[#1]-C-O-[#1]
0.0625	SUB616	N-C-C-O-C
0.0502	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.0101	SUB664	O-C-C-O-[#1]
0.0043	SUB415	S(~C)(~O)
0.0003	SUB537	O=C-C-N
0.0002	SUB647	O=C-N-C-[#1]
PF00583	Acetyltransferase (GNAT),  family
0.6236	SUB594	N-C-C-C-N
0.1835	SUB393	N(~C)(~C)(~H)
PF01094	Receptor family ligand binding region
0.6225	SUB691	O-C-C-C-C-C-O
0.4543	SUB686	O=C-C-C-C-N
0.4169	SUB781	CC1CCC(Cl)CC1
0.3600	SUB718	Cc1ccc(Cl)cc1
0.2906	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.1674	SUB710	C-C(C)-C-C-C
0.1626	SUB21	>= 4 O
0.1614	SUB690	O-C-C-C-C-C-C
0.1611	SUB288	C-F
0.1461	SUB337	C(~C)(~C)(~C)(~N)
0.1436	SUB662	O-C-O-C-C
0.0796	SUB681	O-C-C-C-C-C
0.0066	SUB564	O-C-O-C
PF05652	Scavenger mRNA decapping enzyme (DcpS),  N-terminal
0.6207	SUB408	O(~C)(~P)
0.1231	SUB22	>= 8 O
0.1140	SUB613	N-C-O-C-C
PF00061	Lipocalin / cytosolic fatty-acid binding protein family
0.6197	SUB757	Cc1c(O)cccc1
0.5890	SUB13	>= 16 C
0.5502	SUB535	S-C:C-O
0.4995	SUB762	Oc1c(O)cccc1
0.4620	SUB59	>= 1 Fe
0.3946	SUB337	C(~C)(~C)(~C)(~N)
0.3271	SUB438	C(-C)(-N)(=C)
0.3214	SUB503	N-C=C-[#1]
0.3091	SUB545	O-C:C-O
0.3036	SUB339	C(~C)(~C)(~H)(~N)
0.2800	SUB583	C-C-C-C-C
0.2702	SUB465	N-C-C=C
0.2644	SUB713	C-C(C)-C(C)-C
0.2386	SUB477	C-O-C=C
0.1924	SUB543	O-C:C-[#1]
0.1682	SUB660	O-C-C-N-C
0.1666	SUB582	O=C-C-C-O
0.1476	SUB476	S-C=N-C
0.1474	SUB763	Oc1c(S)cccc1
0.1468	SUB407	O(~C)(~H)
0.1467	SUB695	O=C-C-C-C-C=O
0.1366	SUB564	O-C-O-C
0.1314	SUB381	C(~O)(~O)
0.1074	SUB664	O-C-C-O-[#1]
0.1032	SUB341	C(~C)(~C)(~N)
0.0955	SUB616	N-C-C-O-C
0.0853	SUB697	C-C-C-C-C-C-C-C
0.0839	SUB572	[#1]-C-O-[#1]
0.0683	SUB620	O-C-C=C-C
0.0647	SUB683	O-C-C-C-C-N
0.0634	SUB711	C-C-C(C)-C-C
0.0602	SUB638	O-C-C-C-C
0.0562	SUB643	O-C-C-C=O
0.0448	SUB525	C-C=C-C
0.0057	SUB435	C(-C)(-H)(=C)
0.0045	SUB662	O-C-O-C-C
0.0009	SUB2	>= 8 H
0.0001	SUB826	OC1C(S)CCCC1
0.0001	SUB387	C(:C)(:C)(:N)
PF00520	Ion transport protein
0.6197	SUB200	>= 4 any ring size 6
0.5727	SUB799	CC1CC(O)CCC1
0.5546	SUB460	S(=O)(=O)
0.5189	SUB651	O=C-N-C=O
0.4089	SUB677	N#C-C-C-C
0.4055	SUB666	N-C:C-C-C
0.3294	SUB259	>= 2 hetero-aromatic rings
0.3270	SUB438	C(-C)(-N)(=C)
0.3076	SUB768	Sc1c(N)cccc1
0.3001	SUB606	O=C-C-O-C
0.2948	SUB258	>= 2 aromatic rings
0.2848	SUB675	N-C-N-C:C
0.2643	SUB626	O=C-C:C-O
0.2025	SUB698	C-C-C-C-C-C(C)-C
0.2002	SUB288	C-F
0.1986	SUB486	N:C:C:N
0.1961	SUB300	N-H
0.1936	SUB711	C-C-C(C)-C-C
0.1712	SUB25	>= 2 F
0.1509	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.1340	SUB366	C(~H)(~N)
0.1256	SUB582	O=C-C-C-O
0.1233	SUB570	N-C-C-N
0.1205	SUB339	C(~C)(~C)(~H)(~N)
0.1160	SUB534	S-C:C-N
0.1159	SUB712	C-C(C)(C)-C-C
0.1068	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.1014	SUB392	N(~C)(~C)(~C)
0.0997	SUB4	>= 32 H
0.0923	SUB572	[#1]-C-O-[#1]
0.0917	SUB260	>= 3 aromatic rings
0.0854	SUB340	C(~C)(~C)(~H)(~O)
0.0772	SUB700	O-C-C-C-C-C(C)-C
0.0653	SUB614	C-N-C-C-C
0.0636	SUB215	>= 1 saturated or aromatic carbon-only ring size 7
0.0501	SUB831	SC1C(N)CCCC1
0.0483	SUB636	N-N-C-N-[#1]
0.0479	SUB690	O-C-C-C-C-C-C
0.0437	SUB353	C(~C)(~O)
0.0302	SUB20	>= 2 O
0.0217	SUB624	O=C-C:C-C
0.0204	SUB287	C-O
0.0202	SUB536	O=C-C-C
0.0171	SUB459	S(-O)(=O)
0.0150	SUB202	>= 4 saturated or aromatic nitrogen-containing ring size 6
0.0093	SUB336	C(~C)(~C)(~C)(~H)
0.0061	SUB306	N-S
PF00089	Trypsin
0.6185	SUB437	C(-C)(-H)(=O)
0.5446	SUB208	>= 5 saturated or aromatic carbon-only ring size 6
0.4791	SUB603	O=C-C-N-C
0.4535	SUB594	N-C-C-C-N
0.4064	SUB200	>= 4 any ring size 6
0.3984	SUB663	O-C-C-O-C
0.3477	SUB36	>= 4 S
0.3265	SUB693	O=C-C-C-C-C-C
0.3254	SUB489	N-C=N-[#1]
0.3168	SUB680	C-C-C-C-C-C
0.3024	SUB347	C(~C)(~H)(~O)
0.2748	SUB336	C(~C)(~C)(~C)(~H)
0.2690	SUB433	C(-C)(-C)(=O)
0.2658	SUB179	>= 1 any ring size 6
0.2542	SUB262	>= 4 aromatic rings
0.2535	SUB357	C(~C)(:C)(:C)
0.2532	SUB577	N=C-C:C-[#1]
0.2197	SUB459	S(-O)(=O)
0.1688	SUB647	O=C-N-C-[#1]
0.1517	SUB550	N-C-C:C
0.1484	SUB735	Cc1cc(C)ccc1
0.1190	SUB439	C(-C)(-N)(=N)
0.1091	SUB2	>= 8 H
0.0995	SUB451	C(-N)(=N)
0.0905	SUB348	C(~C)(~H)(~O)(~O)
0.0784	SUB717	Cc1ccc(N)cc1
0.0706	SUB673	O=C-C=C-[#1]
0.0610	SUB644	[#1]-C-C-N-[#1]
0.0402	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0290	SUB444	C(-C)(=O)
0.0202	SUB690	O-C-C-C-C-C-C
0.0163	SUB454	N(-C)(=C)
0.0152	SUB368	C(~H)(~O)(~O)
0.0119	SUB438	C(-C)(-N)(=C)
0.0040	SUB21	>= 4 O
0.0011	SUB598	O=C-C-C:C
PF01168	Alanine racemase, N-terminal domain
0.6148	SUB692	O-C-C-C-C-C-N
PF00594	Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA),  domain
0.6140	SUB460	S(=O)(=O)
0.3967	SUB196	>= 3 saturated or aromatic heteroatom-containing ring size 6
0.3654	SUB253	>= 1 unsaturated non-aromatic carbon-only ring size 10
0.3637	SUB697	C-C-C-C-C-C-C-C
0.3058	SUB683	O-C-C-C-C-N
0.1888	SUB577	N=C-C:C-[#1]
0.1440	SUB339	C(~C)(~C)(~H)(~N)
0.1206	SUB451	C(-N)(=N)
0.0935	SUB186	>= 2 any ring size 6
0.0870	SUB375	C(~H)(~H)(~H)
0.0820	SUB603	O=C-C-N-C
0.0759	SUB706	O=C-C-C-C-C(O)-C
0.0423	SUB644	[#1]-C-C-N-[#1]
0.0253	SUB680	C-C-C-C-C-C
PF08441	Integrin alpha
0.6135	SUB633	C-C-O-C:C
0.2573	SUB4	>= 32 H
0.1058	SUB715	Cc1ccc(O)cc1
0.0935	SUB336	C(~C)(~C)(~C)(~H)
0.0708	SUB350	C(~C)(~H)(~S)
0.0514	SUB627	C-O-C:C-C
0.0414	SUB566	C:C-O-C
0.0218	SUB621	C:C-O-C-C
0.0190	SUB477	C-O-C=C
0.0012	SUB529	[#1]-N-C-[#1]
PF00850	Histone deacetylase domain
0.6107	SUB302	N-O
0.3391	SUB378	C(~N)(:C)(:C)
0.3170	SUB708	O=C-C-C-C-C(N)-C
0.2857	SUB396	N(~C)(~O)
0.1587	SUB689	C-C-C-C-C-C-C
0.1093	SUB685	O=C-C-C-C-C
0.0856	SUB309	O-H
0.0049	SUB658	C-N-C:C-C
0.0002	SUB586	C-C:C-N-C
PF00676	Dehydrogenase E1 component
0.6060	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.3223	SUB158	>= 3 any ring size 5
0.0263	SUB446	C(-H)(-N)(=C)
PF03414	Glycosyltransferase family 6
0.6055	SUB348	C(~C)(~H)(~O)(~O)
0.2859	SUB664	O-C-C-O-[#1]
0.1474	SUB446	C(-H)(-N)(=C)
0.0461	SUB682	O-C-C-C-C-O
PF00160	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
0.6052	SUB603	O=C-C-N-C
0.3434	SUB685	O=C-C-C-C-C
0.2980	SUB660	O-C-C-N-C
0.2761	SUB415	S(~C)(~O)
0.0917	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.0175	SUB684	N-C-C-C-C-C
0.0003	SUB458	S(-C)(=O)
0.0001	SUB18	>= 8 N
PF00183	Hsp90 protein
0.6021	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
PF00171	Aldehyde dehydrogenase family
0.6010	SUB576	O-C-C:C-O
0.5528	SUB36	>= 4 S
0.5319	SUB431	C(-C)(-C)(=C)
0.4591	SUB13	>= 16 C
0.3428	SUB96	>= 1 Hg
0.3007	SUB376	C(~N)(~N)
0.2665	SUB673	O=C-C=C-[#1]
0.2407	SUB668	C=C-C-O-[#1]
0.2302	SUB682	O-C-C-C-C-O
0.2298	SUB347	C(~C)(~H)(~O)
0.2258	SUB600	[#1]-C-C=C-[#1]
0.2159	SUB16	>= 2 N
0.1558	SUB22	>= 8 O
0.1500	SUB509	S=C-N-C
0.1417	SUB694	O=C-C-C-C-C-O
0.1286	SUB1	>= 4 H
0.1251	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0892	SUB378	C(~N)(:C)(:C)
0.0779	SUB554	O=C-C=C
0.0597	SUB158	>= 3 any ring size 5
0.0501	SUB683	O-C-C-C-C-N
PF00432	Prenyltransferase and squalene oxidase repeat
0.6001	SUB190	>= 2 unsaturated non-aromatic carbon-only ring size 6
0.4763	SUB719	Cc1ccc(Br)cc1
0.4502	SUB782	CC1CCC(Br)CC1
0.3830	SUB697	C-C-C-C-C-C-C-C
0.2321	SUB3	>= 16 H
PF01687	Riboflavin kinase
0.5992	SUB548	N-C:C-N
0.2905	SUB771	Nc1c(N)cccc1
0.2019	SUB703	O-C-C-C-C-C-N-C
0.1194	SUB439	C(-C)(-N)(=N)
PF00291	Pyridoxal-phosphate dependent enzyme
0.5970	SUB341	C(~C)(~C)(~N)
0.2074	SUB713	C-C(C)-C(C)-C
0.1725	SUB643	O-C-C-C=O
0.1159	SUB578	C:C-N-C:C
0.1053	SUB704	O-C-C-C-C-C(N)-C
0.0890	SUB531	N:C-C:C
0.0638	SUB537	O=C-C-N
0.0460	SUB536	O=C-C-C
0.0053	SUB437	C(-C)(-H)(=O)
PF00149	Calcineurin-like phosphoesterase
0.5966	SUB698	C-C-C-C-C-C(C)-C
0.5138	SUB414	S(~C)(~H)
0.5137	SUB14	>= 32 C
0.4775	SUB594	N-C-C-C-N
0.4642	SUB338	C(~C)(~C)(~C)(~O)
0.3055	SUB217	>= 1 saturated or aromatic heteroatom-containing ring size 7
0.2278	SUB495	O=C-C:N
0.2142	SUB686	O=C-C-C-C-N
0.2128	SUB642	O-C-C-C=C
0.2117	SUB216	>= 1 saturated or aromatic nitrogen-containing ring size 7
0.1079	SUB603	O=C-C-N-C
0.0921	SUB633	C-C-O-C:C
0.0850	SUB392	N(~C)(~C)(~C)
0.0780	SUB375	C(~H)(~H)(~H)
0.0460	SUB462	O-C-C=N
0.0369	SUB336	C(~C)(~C)(~C)(~H)
0.0223	SUB621	C:C-O-C-C
0.0095	SUB696	O=C-C-C-C-C-N
0.0029	SUB640	O-C-C-C-O
0.0018	SUB687	O=C-C-C-C-O
PF04739	5"-AMP-activated protein kinase beta subunit, interation domain
0.5953	SUB520	N=C-N-C
0.2955	SUB602	N-C:C:C-N
0.0905	SUB561	N-C-N-C
PF02166	Androgen receptor
0.5948	SUB444	C(-C)(=O)
0.3450	SUB644	[#1]-C-C-N-[#1]
0.3148	SUB144	>= 1 any ring size 5
0.3084	SUB822	CC1C(N)CCCC1
0.1286	SUB729	Nc1ccc(N)cc1
0.1090	SUB336	C(~C)(~C)(~C)(~H)
0.0545	SUB25	>= 2 F
0.0040	SUB421	C=O
0.0012	SUB456	N(-O)(=O)
PF00354	Pentaxin family
0.5921	SUB606	O=C-C-O-C
0.4203	SUB441	C(-C)(-O)(=O)
0.2810	SUB309	O-H
0.2394	SUB21	>= 4 O
0.2167	SUB494	O=C-C:C
0.1437	SUB706	O=C-C-C-C-C(O)-C
0.1422	SUB624	O=C-C:C-C
0.1182	SUB702	O-C-C-C-C-C(O)-C
0.0700	SUB398	N(~C)(:C)(:C)
0.0152	SUB375	C(~H)(~H)(~H)
PF10526	NADH-ubiquinone reductase complex 1 MLRQ subunit
0.5910	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.2168	SUB158	>= 3 any ring size 5
0.0751	SUB674	O=C-C=C-N
PF00043	Glutathione S-transferase, C-terminal domain
0.5906	SUB814	NC1CC(Cl)CCC1
0.4309	SUB751	Nc1cc(Cl)ccc1
0.4116	SUB578	C:C-N-C:C
0.4100	SUB200	>= 4 any ring size 6
0.3074	SUB664	O-C-C-O-[#1]
0.2252	SUB807	OC1CC(Cl)CCC1
0.1909	SUB2	>= 8 H
0.1655	SUB1	>= 4 H
0.1302	SUB20	>= 2 O
0.1277	SUB756	Cc1c(C)cccc1
0.1054	SUB709	C-C(C)-C-C
0.1045	SUB295	C-Cl
0.0963	SUB670	Cl-C:C-C=O
0.0812	SUB367	C(~H)(~O)
0.0528	SUB13	>= 16 C
0.0417	SUB350	C(~C)(~H)(~S)
0.0234	SUB587	C-S-C-C-C
0.0154	SUB597	N=C-N-C-C
0.0030	SUB718	Cc1ccc(Cl)cc1
PF00493	MCM2/3/5 family
0.5886	SUB14	>= 32 C
0.3662	SUB365	C(~F)(:C)
0.2203	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.1522	SUB686	O=C-C-C-C-N
0.1489	SUB262	>= 4 aromatic rings
0.1087	SUB625	O=C-C:C-N
PF07722	Peptidase C26
0.5884	SUB694	O=C-C-C-C-C-O
0.5000	SUB414	S(~C)(~H)
0.1821	SUB695	O=C-C-C-C-C=O
PF06512	Sodium ion transport-associated
0.5865	SUB598	O=C-C-C:C
0.2656	SUB341	C(~C)(~C)(~N)
0.2634	SUB300	N-H
0.2307	SUB375	C(~H)(~H)(~H)
0.2305	SUB12	>= 8 C
0.2145	SUB581	O=C-C-C-N
0.1557	SUB251	>= 1 saturated or aromatic nitrogen-containing ring size 10
0.1544	SUB658	C-N-C:C-C
0.1457	SUB347	C(~C)(~H)(~O)
0.1410	SUB615	C-C-O-C-C
0.1310	SUB619	C:C-C-C:C
0.1282	SUB444	C(-C)(=O)
0.0950	SUB605	C-O-C-C:C
0.0811	SUB655	N-C-N-C-C
0.0756	SUB722	Oc1ccc(N)cc1
0.0517	SUB392	N(~C)(~C)(~C)
0.0386	SUB367	C(~H)(~O)
0.0173	SUB785	OC1CCC(N)CC1
0.0145	SUB603	O=C-C-N-C
0.0116	SUB561	N-C-N-C
0.0038	SUB666	N-C:C-C-C
0.0019	SUB586	C-C:C-N-C
0.0006	SUB831	SC1C(N)CCCC1
0.0003	SUB534	S-C:C-N
0.0002	SUB768	Sc1c(N)cccc1
PF02882	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P), -binding domain
0.5852	SUB674	O=C-C=C-N
0.1158	SUB488	N-C=N-C
0.1127	SUB691	O-C-C-C-C-C-O
0.0538	SUB444	C(-C)(=O)
0.0133	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF05889	Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen), 
0.5850	SUB588	N-C:C-O-[#1]
0.0710	SUB544	O-C:C-N
PF04389	Peptidase family M28
0.5824	SUB695	O=C-C-C-C-C=O
0.3478	SUB486	N:C:C:N
0.2744	SUB436	C(-C)(-H)(=N)
0.1565	SUB500	N-C:C:N
0.1275	SUB694	O=C-C-C-C-C-O
0.1060	SUB548	N-C:C-N
0.0318	SUB346	C(~C)(~H)(~N)
PF02219	Methylenetetrahydrofolate reductase
0.5823	SUB674	O=C-C=C-N
0.5450	SUB708	O=C-C-C-C-C(N)-C
0.1522	SUB717	Cc1ccc(N)cc1
0.1092	SUB249	>= 1 any ring size 10
0.0100	SUB694	O=C-C-C-C-C-O
PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
0.5817	SUB433	C(-C)(-C)(=O)
0.2976	SUB387	C(:C)(:C)(:N)
0.2760	SUB602	N-C:C:C-N
0.2618	SUB22	>= 8 O
0.2485	SUB17	>= 4 N
0.2415	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.2112	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.1959	SUB499	O-C=C-C
0.1515	SUB674	O=C-C=C-N
0.1501	SUB151	>= 2 any ring size 5
0.0476	SUB16	>= 2 N
0.0441	SUB741	Oc1cc(O)ccc1
0.0429	SUB654	O-C:C:C-O
0.0350	SUB477	C-O-C=C
0.0155	SUB612	N-C-C-N-C
PF00168	C2 domain
0.5806	SUB408	O(~C)(~P)
0.5124	SUB799	CC1CC(O)CCC1
0.4898	SUB718	Cc1ccc(Cl)cc1
0.2286	SUB751	Nc1cc(Cl)ccc1
0.1043	SUB339	C(~C)(~C)(~H)(~N)
0.1036	SUB529	[#1]-N-C-[#1]
0.0655	SUB406	O(~C)(~C)
0.0177	SUB375	C(~H)(~H)(~H)
0.0136	SUB3	>= 16 H
0.0087	SUB582	O=C-C-C-O
0.0016	SUB814	NC1CC(Cl)CCC1
PF00282	Pyridoxal-dependent decarboxylase conserved domain
0.5787	SUB537	O=C-C-N
0.5173	SUB686	O=C-C-C-C-N
0.4342	SUB567	O-C-C-N
0.2484	SUB591	C-C:C-O-[#1]
0.1654	SUB704	O-C-C-C-C-C(N)-C
0.1496	SUB437	C(-C)(-H)(=O)
0.1245	SUB536	O=C-C-C
0.1148	SUB713	C-C(C)-C(C)-C
0.0902	SUB446	C(-H)(-N)(=C)
0.0319	SUB700	O-C-C-C-C-C(C)-C
0.0157	SUB618	C-C-C-O-[#1]
0.0133	SUB578	C:C-N-C:C
0.0010	SUB373	C(~H)(:C)(:N)
0.0009	SUB436	C(-C)(-H)(=N)
PF00549	CoA-ligase
0.5780	SUB688	O=C-C-C-C=O
0.1974	SUB682	O-C-C-C-C-O
0.0342	SUB687	O=C-C-C-C-O
PF01387	Synuclein
0.5770	SUB386	C(:C)(:C)(:C)
0.3078	SUB387	C(:C)(:C)(:N)
0.1046	SUB401	N(~H)(:C)(:C)
0.0149	SUB759	Cc1c(N)cccc1
PF00342	Phosphoglucose isomerase
0.5759	SUB572	[#1]-C-O-[#1]
0.1183	SUB582	O=C-C-C-O
PF04321	RmlD substrate binding domain
0.5736	SUB413	S(~C)(~C)
0.1334	SUB508	C-C-S-C
PF00271	Helicase conserved C-terminal domain
0.5729	SUB688	O=C-C-C-C=O
0.0702	SUB582	O=C-C-C-O
0.0537	SUB643	O-C-C-C=O
PF01144	Coenzyme A transferase
0.5724	SUB688	O=C-C-C-C=O
0.1173	SUB682	O-C-C-C-C-O
PF00266	Aminotransferase class-V
0.5688	SUB588	N-C:C-O-[#1]
0.4527	SUB567	O-C-C-N
0.3280	SUB498	O-C:C:N
0.3273	SUB444	C(-C)(=O)
0.3185	SUB683	O-C-C-C-C-N
0.1194	SUB441	C(-C)(-O)(=O)
0.1144	SUB695	O=C-C-C-C-C=O
0.0001	SUB373	C(~H)(:C)(:N)
PF00287	Sodium / potassium ATPase beta chain
0.5681	SUB469	O=S-C-N
0.3255	SUB476	S-C=N-C
0.2551	SUB479	S-C=N-[#1]
PF03951	Glutamine synthetase, beta-Grasp domain
0.5655	SUB695	O=C-C-C-C-C=O
PF01122	Eukaryotic cobalamin-binding protein
0.5652	SUB172	>= 5 any ring size 5
0.4889	SUB60	>= 1 Co
0.3071	SUB801	CC1CC(N)CCC1
0.2978	SUB738	Cc1cc(N)ccc1
PF08336	Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
0.5635	SUB636	N-N-C-N-[#1]
0.1722	SUB518	N-N-C-N
0.1207	SUB346	C(~C)(~H)(~N)
0.1080	SUB366	C(~H)(~N)
0.0645	SUB511	[#1]-N-N-[#1]
0.0326	SUB684	N-C-C-C-C-C
0.0115	SUB251	>= 1 saturated or aromatic nitrogen-containing ring size 10
0.0103	SUB11	>= 4 C
0.0009	SUB593	N-C-C-C-C
0.0007	SUB487	N-C:N:N
PF02065	Melibiase
0.5630	SUB664	O-C-C-O-[#1]
0.2170	SUB572	[#1]-C-O-[#1]
PF00105	Zinc finger, C4 type (two domains), 
0.5611	SUB715	Cc1ccc(O)cc1
0.4527	SUB840	CC1CC(C)CC1
0.3841	SUB720	Oc1ccc(O)cc1
0.3107	SUB296	C-As
0.3045	SUB48	>= 2 I
0.3026	SUB633	C-C-O-C:C
0.3003	SUB522	C:N-C-[#1]
0.2694	SUB738	Cc1cc(N)ccc1
0.2661	SUB14	>= 32 C
0.2480	SUB735	Cc1cc(C)ccc1
0.2340	SUB381	C(~O)(~O)
0.2276	SUB621	C:C-O-C-C
0.2187	SUB629	C-N-C-C:C
0.2063	SUB201	>= 4 saturated or aromatic carbon-only ring size 6
0.2003	SUB467	N#C-C=C
0.1848	SUB446	C(-H)(-N)(=C)
0.1518	SUB644	[#1]-C-C-N-[#1]
0.1187	SUB717	Cc1ccc(N)cc1
0.1083	SUB591	C-C:C-O-[#1]
0.1050	SUB703	O-C-C-C-C-C-N-C
0.1041	SUB677	N#C-C-C-C
0.1003	SUB699	O-C-C-C-C-C-C-C
0.1000	SUB674	O=C-C=C-N
0.0899	SUB702	O-C-C-C-C-C(O)-C
0.0871	SUB440	C(-C)(-N)(=O)
0.0707	SUB441	C(-C)(-O)(=O)
0.0675	SUB375	C(~H)(~H)(~H)
0.0617	SUB494	O=C-C:C
0.0566	SUB448	C(-H)(=N)
0.0480	SUB687	O=C-C-C-C-O
0.0393	SUB756	Cc1c(C)cccc1
0.0385	SUB681	O-C-C-C-C-C
0.0335	SUB646	O=C-N-C-C
0.0235	SUB777	CC1CCC(C)CC1
0.0230	SUB779	CC1CCC(S)CC1
0.0127	SUB461	C-C-C#C
0.0122	SUB179	>= 1 any ring size 6
0.0114	SUB665	C-C=C-C=C
0.0098	SUB392	N(~C)(~C)(~C)
0.0033	SUB565	C=C-C=C
0.0032	SUB821	CC1C(S)CCCC1
0.0022	SUB19	>= 1 O
0.0020	SUB714	Cc1ccc(C)cc1
0.0018	SUB482	O-S-C:C
0.0013	SUB533	S-C:C-[#1]
PF00405	Transferrin
0.5576	SUB381	C(~O)(~O)
0.4287	SUB52	>= 1 Al
0.2733	SUB664	O-C-C-O-[#1]
0.2284	SUB643	O-C-C-C=O
0.1934	SUB582	O=C-C-C-O
0.0654	SUB589	O=C-C-C=O
0.0039	SUB813	NC1CC(N)CCC1
0.0039	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
PF02214	K+ channel tetramerisation domain
0.5520	SUB367	C(~H)(~O)
0.1265	SUB315	O-P
0.0250	SUB412	P(~O)(~O)
0.0143	SUB31	>= 1 P
0.0046	SUB408	O(~C)(~P)
PF02159	Oestrogen receptor
0.5518	SUB703	O-C-C-C-C-C-N-C
0.5144	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.3982	SUB346	C(~C)(~H)(~N)
0.2603	SUB736	Cc1cc(O)ccc1
0.1645	SUB144	>= 1 any ring size 5
0.0754	SUB700	O-C-C-C-C-C(C)-C
0.0733	SUB684	N-C-C-C-C-C
0.0450	SUB260	>= 3 aromatic rings
0.0141	SUB608	N-C-C-C:C
0.0113	SUB665	C-C=C-C=C
0.0071	SUB565	C=C-C=C
PF00026	Eukaryotic aspartyl protease
0.5514	SUB696	O=C-C-C-C-C-N
0.4043	SUB594	N-C-C-C-N
0.2007	SUB4	>= 32 H
0.1118	SUB646	O=C-N-C-C
0.1085	SUB647	O=C-N-C-[#1]
0.0622	SUB698	C-C-C-C-C-C(C)-C
0.0600	SUB705	O=C-C-C-C-C-C-C
0.0526	SUB14	>= 32 C
PF00153	Mitochondrial carrier protein
0.5500	SUB567	O-C-C-N
0.4526	SUB580	O=C-C-C-C
0.3795	SUB32	>= 2 P
0.3438	SUB361	C(~Cl)(~Cl)
0.2706	SUB638	O-C-C-C-C
0.1883	SUB696	O=C-C-C-C-C-N
0.1576	SUB686	O=C-C-C-C-N
0.1545	SUB683	O-C-C-C-C-N
0.1100	SUB21	>= 4 O
0.1099	SUB486	N:C:C:N
0.0376	SUB500	N-C:C:N
0.0274	SUB581	O=C-C-C-N
0.0061	SUB548	N-C:C-N
PF00351	Biopterin-dependent aromatic amino acid hydroxylase
0.5485	SUB537	O=C-C-N
0.5070	SUB567	O-C-C-N
0.1038	SUB664	O-C-C-O-[#1]
0.0894	SUB618	C-C-C-O-[#1]
0.0522	SUB339	C(~C)(~C)(~H)(~N)
PF01467	Cytidylyltransferase
0.5477	SUB660	O-C-C-N-C
0.2185	SUB392	N(~C)(~C)(~C)
0.2132	SUB624	O=C-C:C-C
0.1940	SUB703	O-C-C-C-C-C-N-C
0.1527	SUB572	[#1]-C-O-[#1]
0.0688	SUB696	O=C-C-C-C-C-N
0.0600	SUB32	>= 2 P
0.0594	SUB673	O=C-C=C-[#1]
0.0583	SUB22	>= 8 O
0.0441	SUB457	P(-O)(=O)
0.0386	SUB408	O(~C)(~P)
0.0341	SUB531	N:C-C:C
0.0339	SUB613	N-C-O-C-C
PF00017	SH2 domain
0.5477	SUB714	Cc1ccc(C)cc1
0.5105	SUB360	C(~C)(:N)(:N)
0.4783	SUB715	Cc1ccc(O)cc1
0.3406	SUB494	O=C-C:C
0.3108	SUB259	>= 2 hetero-aromatic rings
0.2884	SUB568	O-C-C-O
0.2666	SUB193	>= 3 any ring size 6
0.2383	SUB522	C:N-C-[#1]
0.2216	SUB759	Cc1c(N)cccc1
0.1870	SUB426	P=O
0.1855	SUB3	>= 16 H
0.1725	SUB682	O-C-C-C-C-O
0.1680	SUB684	N-C-C-C-C-C
0.1368	SUB646	O=C-N-C-C
0.1317	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0892	SUB622	N-C:C:C:N
0.0865	SUB412	P(~O)(~O)
0.0864	SUB31	>= 1 P
0.0864	SUB703	O-C-C-C-C-C-N-C
0.0783	SUB602	N-C:C:C-N
0.0648	SUB738	Cc1cc(N)ccc1
0.0570	SUB708	O=C-C-C-C-C(N)-C
0.0543	SUB4	>= 32 H
0.0508	SUB261	>= 3 hetero-aromatic rings
0.0072	SUB567	O-C-C-N
PF07992	Pyridine nucleotide-disulphide oxidoreductase
0.5460	SUB18	>= 8 N
0.2527	SUB21	>= 4 O
0.2208	SUB414	S(~C)(~H)
0.1202	SUB22	>= 8 O
0.0585	SUB646	O=C-N-C-C
0.0334	SUB655	N-C-N-C-C
0.0125	SUB262	>= 4 aromatic rings
0.0060	SUB561	N-C-N-C
0.0033	SUB350	C(~C)(~H)(~S)
0.0029	SUB35	>= 2 S
0.0020	SUB369	C(~H)(~S)
PF01066	CDP-alcohol phosphatidyltransferase
0.5435	SUB572	[#1]-C-O-[#1]
PF00531	Death domain
0.5429	SUB673	O=C-C=C-[#1]
0.2225	SUB21	>= 4 O
0.2210	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.2050	SUB376	C(~N)(~N)
0.0446	SUB359	C(~C)(:N)
PF00293	NUDIX domain
0.5410	SUB348	C(~C)(~H)(~O)(~O)
0.1685	SUB368	C(~H)(~O)(~O)
PF01923	Cobalamin adenosyltransferase
0.5398	SUB834	NC1C(N)CCCC1
0.1929	SUB486	N:C:C:N
0.1346	SUB60	>= 1 Co
0.1306	SUB801	CC1CC(N)CCC1
0.0850	SUB500	N-C:C:N
0.0746	SUB771	Nc1c(N)cccc1
0.0733	SUB548	N-C:C-N
0.0328	SUB172	>= 5 any ring size 5
0.0318	SUB398	N(~C)(:C)(:C)
PF02059	Interleukin-3
0.5388	SUB707	O=C-C-C-C-C(=O)-C
0.5242	SUB695	O=C-C-C-C-C=O
PF00328	Histidine acid phosphatase
0.5376	SUB664	O-C-C-O-[#1]
0.3978	SUB349	C(~C)(~H)(~P)
0.1897	SUB393	N(~C)(~C)(~H)
0.0853	SUB309	O-H
PF01182	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
0.5374	SUB702	O-C-C-C-C-C(O)-C
0.1545	SUB408	O(~C)(~P)
0.0418	SUB682	O-C-C-C-C-O
PF00060	Ligand-gated ion channel
0.5352	SUB686	O=C-C-C-C-N
0.3407	SUB345	C(~C)(~H)
0.2013	SUB453	C(-O)(=O)
0.1622	SUB681	O-C-C-C-C-C
0.1008	SUB353	C(~C)(~O)
0.0921	SUB567	O-C-C-N
0.0723	SUB34	>= 1 S
0.0416	SUB694	O=C-C-C-C-C-O
PF06628	Catalase-related immune-responsive
0.5339	SUB622	N-C:C:C:N
0.2700	SUB441	C(-C)(-O)(=O)
0.2278	SUB375	C(~H)(~H)(~H)
PF00664	ABC transporter transmembrane region
0.5295	SUB516	N-N-C-C
0.3350	SUB699	O-C-C-C-C-C-C-C
0.2852	SUB519	O=C-N-N
0.2408	SUB698	C-C-C-C-C-C(C)-C
0.2323	SUB825	OC1C(O)CCCC1
0.2312	SUB567	O-C-C-N
0.1962	SUB627	C-O-C:C-C
0.1953	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.1924	SUB590	C-C:C-O-C
0.1780	SUB566	C:C-O-C
0.1515	SUB466	O=S-C-C
0.1142	SUB709	C-C(C)-C-C
0.1077	SUB346	C(~C)(~H)(~N)
0.0972	SUB777	CC1CCC(C)CC1
0.0899	SUB442	C(-C)(=C)
0.0850	SUB253	>= 1 unsaturated non-aromatic carbon-only ring size 10
0.0725	SUB417	C=C
0.0495	SUB660	O-C-C-N-C
0.0408	SUB3	>= 16 H
0.0394	SUB735	Cc1cc(C)ccc1
0.0386	SUB133	>= 1 saturated or aromatic heteroatom-containing ring size 4
0.0207	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.0044	SUB66	>= 1 As
0.0012	SUB137	>= 2 any ring size 4
0.0009	SUB140	>= 2 saturated or aromatic heteroatom-containing ring size 4
PF03489	Saposin-like type B, region 2
0.5272	SUB567	O-C-C-N
PF01030	Receptor L domain
0.5269	SUB735	Cc1cc(C)ccc1
0.2961	SUB621	C:C-O-C-C
0.1640	SUB492	C-N:C-[#1]
0.1047	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0992	SUB374	C(~H)(:N)
0.0442	SUB637	C-N-C-N-C
0.0430	SUB759	Cc1c(N)cccc1
0.0252	SUB683	O-C-C-C-C-N
0.0101	SUB380	C(~N)(:N)
0.0042	SUB573	N:C:N:C
0.0036	SUB633	C-C-O-C:C
0.0004	SUB390	C(:N)(:N)
PF03360	Glycosyltransferase family 43
0.5263	SUB682	O-C-C-C-C-O
0.2037	SUB651	O=C-N-C=O
0.1521	SUB664	O-C-C-O-[#1]
0.0360	SUB648	O=C-N-C-N
PF01425	Amidase
0.5235	SUB336	C(~C)(~C)(~C)(~H)
PF00085	Thioredoxin
0.5234	SUB692	O-C-C-C-C-C-N
0.0007	SUB339	C(~C)(~C)(~H)(~N)
PF08246	Cathepsin propeptide inhibitor domain (I29), 
0.5226	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.3868	SUB21	>= 4 O
0.2861	SUB612	N-C-C-N-C
0.2840	SUB339	C(~C)(~C)(~H)(~N)
0.1147	SUB466	O=S-C-C
0.0343	SUB367	C(~H)(~O)
0.0090	SUB647	O=C-N-C-[#1]
0.0025	SUB449	C(-H)(=O)
PF00265	Thymidine kinase
0.5210	SUB664	O-C-C-O-[#1]
0.1278	SUB572	[#1]-C-O-[#1]
PF01808	AICARFT/IMPCHase bienzyme
0.5201	SUB674	O=C-C=C-N
PF05118	Aspartyl/Asparaginyl beta-hydroxylase
0.5169	SUB688	O=C-C-C-C=O
0.2016	SUB682	O-C-C-C-C-O
PF01067	Calpain large subunit, domain III
0.5163	SUB433	C(-C)(-C)(=O)
PF08763	Voltage gated calcium channel IQ domain
0.5161	SUB695	O=C-C-C-C-C=O
0.4126	SUB690	O-C-C-C-C-C-C
0.3489	SUB686	O=C-C-C-C-N
0.2277	SUB3	>= 16 H
0.1708	SUB336	C(~C)(~C)(~C)(~H)
0.0709	SUB51	>= 1 Mg
0.0653	SUB200	>= 4 any ring size 6
0.0537	SUB441	C(-C)(-O)(=O)
PF00146	NADH dehydrogenase
0.5143	SUB364	C(~F)(~F)
0.3521	SUB25	>= 2 F
0.2088	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1305	SUB457	P(-O)(=O)
0.0594	SUB426	P=O
0.0404	SUB406	O(~C)(~C)
0.0318	SUB315	O-P
0.0291	SUB412	P(~O)(~O)
PF02180	Bcl-2 homology region 4
0.5139	SUB629	C-N-C-C:C
0.0696	SUB639	O-C-C-C-N
0.0375	SUB235	>= 2 any ring size 8
0.0320	SUB713	C-C(C)-C(C)-C
0.0157	SUB799	CC1CC(O)CCC1
0.0124	SUB260	>= 3 aromatic rings
0.0104	SUB700	O-C-C-C-C-C(C)-C
0.0097	SUB640	O-C-C-C-O
PF00130	Phorbol esters/diacylglycerol binding domain (C1 domain), 
0.5129	SUB408	O(~C)(~P)
0.4572	SUB615	C-C-O-C-C
0.3382	SUB621	C:C-O-C-C
0.3297	SUB738	Cc1cc(N)ccc1
0.2543	SUB537	O=C-C-N
0.2146	SUB3	>= 16 H
0.2081	SUB714	Cc1ccc(C)cc1
0.0846	SUB633	C-C-O-C:C
0.0201	SUB529	[#1]-N-C-[#1]
0.0191	SUB644	[#1]-C-C-N-[#1]
PF00406	Adenylate kinase
0.5129	SUB439	C(-C)(-N)(=N)
0.1101	SUB703	O-C-C-C-C-C-N-C
PF05047	Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain 
0.5116	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0962	SUB389	C(:C)(:N)(:N)
0.0501	SUB360	C(~C)(:N)(:N)
0.0470	SUB398	N(~C)(:C)(:C)
PF02189	Immunoreceptor tyrosine-based activation motif
0.5112	SUB490	N-C-S-C
PF06327	Domain of Unknown Function (DUF1053), 
0.5103	SUB250	>= 1 saturated or aromatic carbon-only ring size 10
0.1692	SUB801	CC1CC(N)CCC1
PF00364	Biotin-requiring enzyme
0.5099	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.3275	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
0.1576	SUB612	N-C-C-N-C
0.1185	SUB536	O=C-C-C
PF08725	Integrin beta cytoplasmic domain
0.5095	SUB4	>= 32 H
0.2182	SUB350	C(~C)(~H)(~S)
0.1604	SUB441	C(-C)(-O)(=O)
0.0439	SUB705	O=C-C-C-C-C-C-C
0.0274	SUB642	O-C-C-C=C
0.0272	SUB700	O-C-C-C-C-C(C)-C
0.0221	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0001	SUB369	C(~H)(~S)
PF00501	AMP-binding enzyme
0.5081	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.3102	SUB681	O-C-C-C-C-C
0.2964	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.2140	SUB13	>= 16 C
0.2093	SUB783	OC1CCC(O)CC1
0.1090	SUB682	O-C-C-C-C-O
0.0959	SUB720	Oc1ccc(O)cc1
0.0845	SUB398	N(~C)(:C)(:C)
0.0603	SUB548	N-C:C-N
0.0401	SUB442	C(-C)(=C)
0.0379	SUB685	O=C-C-C-C-C
0.0366	SUB417	C=C
0.0356	SUB387	C(:C)(:C)(:N)
0.0290	SUB500	N-C:C:N
0.0171	SUB389	C(:C)(:N)(:N)
0.0164	SUB735	Cc1cc(C)ccc1
0.0129	SUB12	>= 8 C
PF02544	3-oxo-5-alpha-steroid 4-dehydrogenase 
0.5065	SUB705	O=C-C-C-C-C-C-C
0.4497	SUB801	CC1CC(N)CCC1
0.1974	SUB145	>= 1 saturated or aromatic carbon-only ring size 5
0.1197	SUB861	CC1C(C)CCC1
0.0042	SUB243	>= 1 saturated or aromatic carbon-only ring size 9
0.0023	SUB840	CC1CC(C)CC1
PF03807	NADP oxidoreductase coenzyme F420-dependent
0.5059	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.3813	SUB580	O=C-C-C-C
0.2353	SUB692	O-C-C-C-C-C-N
0.0614	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF01582	TIR domain
0.5051	SUB386	C(:C)(:C)(:C)
0.3115	SUB252	>= 1 saturated or aromatic heteroatom-containing ring size 10
0.2314	SUB759	Cc1c(N)cccc1
0.0330	SUB822	CC1C(N)CCCC1
0.0185	SUB622	N-C:C:C:N
PF01112	Asparaginase
0.5051	SUB687	O=C-C-C-C-O
0.3659	SUB688	O=C-C-C-C=O
PF00294	pfkB family carbohydrate kinase
0.5029	SUB588	N-C:C-O-[#1]
0.2885	SUB544	O-C:C-N
0.1739	SUB498	O-C:C:N
0.0447	SUB462	O-C-C=N
PF00245	Alkaline phosphatase
0.5018	SUB350	C(~C)(~H)(~S)
0.1310	SUB369	C(~H)(~S)
PF00792	Phosphoinositide 3-kinase C2
0.5007	SUB771	Nc1c(N)cccc1
0.0704	SUB738	Cc1cc(N)ccc1
0.0406	SUB522	C:N-C-[#1]
0.0001	SUB717	Cc1ccc(N)cc1
PF00629	MAM domain
0.5000	SUB32	>= 2 P
PF00012	Hsp70 protein
0.5000	SUB613	N-C-O-C-C
PF01208	Uroporphyrinogen decarboxylase (URO-D), 
0.5000	SUB414	S(~C)(~H)
0.2414	SUB153	>= 2 saturated or aromatic nitrogen-containing ring size 5
0.1984	SUB263	>= 4 hetero-aromatic rings
0.1823	SUB167	>= 4 saturated or aromatic nitrogen-containing ring size 5
0.1064	SUB400	N(~H)(:C)
0.0908	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF03921	Intercellular adhesion molecule (ICAM), , N-terminal domain
0.5000	SUB190	>= 2 unsaturated non-aromatic carbon-only ring size 6
PF07970	Endoplasmic reticulum vesicle transporter 
0.5000	SUB66	>= 1 As
PF05328	CybS
0.5000	SUB687	O=C-C-C-C-O
PF05721	Phytanoyl-CoA dioxygenase (PhyH), 
0.5000	SUB606	O=C-C-O-C
PF00631	GGL domain
0.5000	SUB330	C(~Br)(~H)
PF00031	Cystatin domain
0.5000	SUB783	OC1CCC(O)CC1
PF02038	ATP1G1/PLM/MAT8 family
0.5000	SUB809	SC1CC(S)CCC1
PF00403	Heavy-metal-associated domain
0.5000	SUB611	C-O-C-O-C
PF00346	Respiratory-chain NADH dehydrogenase, 49 Kd subunit
0.5000	SUB158	>= 3 any ring size 5
PF00170	bZIP transcription factor
0.5000	SUB66	>= 1 As
0.4081	SUB158	>= 3 any ring size 5
0.3705	SUB151	>= 2 any ring size 5
0.2881	SUB200	>= 4 any ring size 6
0.2804	SUB827	OC1C(N)CCCC1
0.2507	SUB392	N(~C)(~C)(~C)
0.1939	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.1904	SUB360	C(~C)(:N)(:N)
0.1340	SUB756	Cc1c(C)cccc1
0.0159	SUB147	>= 1 saturated or aromatic heteroatom-containing ring size 5
PF00076	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain), 
0.5000	SUB589	O=C-C-C=O
PF00188	Cysteine-rich secretory protein family
0.5000	SUB409	O(~H)(~S)
PF00717	Peptidase S24-like
0.5000	SUB215	>= 1 saturated or aromatic carbon-only ring size 7
PF12126	Protein of unknown function (DUF3583), 
0.5000	SUB133	>= 1 saturated or aromatic heteroatom-containing ring size 4
PF07221	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase), 
0.5000	SUB348	C(~C)(~H)(~O)(~O)
PF03453	MoeA N-terminal region (domain I and II), 
0.5000	SUB449	C(-H)(=O)
PF01227	GTP cyclohydrolase I
0.5000	SUB333	C(~C)(~C)
PF01019	Gamma-glutamyltranspeptidase
0.5000	SUB695	O=C-C-C-C-C=O
PF02984	Cyclin, C-terminal domain
0.5000	SUB140	>= 2 saturated or aromatic heteroatom-containing ring size 4
PF00273	Serum albumin family
0.5000	SUB52	>= 1 Al
0.2476	SUB407	O(~C)(~H)
0.2170	SUB34	>= 1 S
0.2119	SUB285	C-C
0.1984	SUB345	C(~C)(~H)
0.1675	SUB284	C-H
0.1464	SUB10	>= 2 C
0.1244	SUB704	O-C-C-C-C-C(N)-C
0.1159	SUB643	O-C-C-C=O
0.0647	SUB4	>= 32 H
0.0534	SUB435	C(-C)(-H)(=C)
0.0505	SUB337	C(~C)(~C)(~C)(~N)
0.0406	SUB666	N-C:C-C-C
0.0290	SUB601	N-C:C:C-C
0.0169	SUB672	O=C-C=C-C
0.0138	SUB491	C-C-C=C
0.0133	SUB433	C(-C)(-C)(=O)
0.0125	SUB861	CC1C(C)CCC1
0.0078	SUB582	O=C-C-C-O
0.0069	SUB624	O=C-C:C-C
0.0062	SUB679	C-C-C=C-C
0.0056	SUB661	C-C=C-C-C
0.0040	SUB444	C(-C)(=O)
0.0004	SUB641	C=C-C-C-C
0.0003	SUB557	C=C-C-C
PF00514	Armadillo/beta-catenin-like repeat
0.5000	SUB5	>= 1 Li
PF01433	Peptidase family M1
0.4972	SUB340	C(~C)(~C)(~H)(~O)
0.3356	SUB694	O=C-C-C-C-C-O
0.3059	SUB441	C(-C)(-O)(=O)
0.1501	SUB444	C(-C)(=O)
0.1268	SUB647	O=C-N-C-[#1]
0.0528	SUB132	>= 1 saturated or aromatic nitrogen-containing ring size 4
0.0100	SUB572	[#1]-C-O-[#1]
0.0065	SUB336	C(~C)(~C)(~C)(~H)
PF01401	Angiotensin-converting enzyme
0.4964	SUB381	C(~O)(~O)
0.3827	SUB703	O-C-C-C-C-C-N-C
0.3686	SUB647	O=C-N-C-[#1]
0.2853	SUB700	O-C-C-C-C-C(C)-C
0.2773	SUB339	C(~C)(~C)(~H)(~N)
0.2248	SUB252	>= 1 saturated or aromatic heteroatom-containing ring size 10
0.2206	SUB660	O-C-C-N-C
0.2122	SUB441	C(-C)(-O)(=O)
0.0773	SUB759	Cc1c(N)cccc1
0.0473	SUB615	C-C-O-C-C
PF00702	haloacid dehalogenase-like hydrolase
0.4928	SUB140	>= 2 saturated or aromatic heteroatom-containing ring size 4
0.3712	SUB25	>= 2 F
0.3636	SUB52	>= 1 Al
0.2509	SUB437	C(-C)(-H)(=O)
0.2452	SUB675	N-C-N-C:C
0.2088	SUB12	>= 8 C
0.2058	SUB39	>= 2 Cl
0.1950	SUB703	O-C-C-C-C-C-N-C
0.1794	SUB620	O-C-C=C-C
0.1718	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.1373	SUB660	O-C-C-N-C
0.1267	SUB704	O-C-C-C-C-C(N)-C
0.1090	SUB629	C-N-C-C:C
0.1014	SUB607	O-C:C-C-C
0.0927	SUB667	C=C-C-O-C
0.0846	SUB634	N-C-C:C-C
0.0647	SUB496	C-N-C:C
0.0553	SUB652	O-C:C:C-C
0.0447	SUB375	C(~H)(~H)(~H)
0.0265	SUB373	C(~H)(:C)(:N)
0.0173	SUB137	>= 2 any ring size 4
0.0151	SUB778	CC1CCC(O)CC1
0.0123	SUB66	>= 1 As
0.0063	SUB51	>= 1 Mg
PF00002	7 transmembrane receptor (Secretin family), 
0.4927	SUB23	>= 16 O
0.2595	SUB489	N-C=N-[#1]
PF11628	T-cell surface glycoprotein CD3 zeta chain
0.4888	SUB490	N-C-S-C
PF00643	B-box zinc finger
0.4879	SUB631	O-C:C-O-C
0.2459	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
0.1823	SUB736	Cc1cc(O)ccc1
0.1408	SUB757	Cc1c(O)cccc1
0.1297	SUB703	O-C-C-C-C-C-N-C
0.1228	SUB756	Cc1c(C)cccc1
PF10420	Cytokine interleukin-12p40 C-terminus
0.4873	SUB381	C(~O)(~O)
0.0209	SUB690	O-C-C-C-C-C-C
0.0020	SUB618	C-C-C-O-[#1]
PF03493	Calcium-activated BK potassium channel alpha subunit
0.4853	SUB249	>= 1 any ring size 10
0.2462	SUB343	C(~C)(~Cl)
0.1749	SUB295	C-Cl
0.0407	SUB496	C-N-C:C
0.0162	SUB751	Nc1cc(Cl)ccc1
0.0015	SUB814	NC1CC(Cl)CCC1
0.0001	SUB658	C-N-C:C-C
PF01434	Peptidase family M41
0.4816	SUB261	>= 3 hetero-aromatic rings
PF01063	Aminotransferase class IV
0.4804	SUB441	C(-C)(-O)(=O)
0.3146	SUB683	O-C-C-C-C-N
0.2072	SUB334	C(~C)(~C)(~C)
0.1446	SUB407	O(~C)(~H)
0.1069	SUB709	C-C(C)-C-C
0.0928	SUB462	O-C-C=N
0.0033	SUB309	O-H
PF02460	Patched family
0.4788	SUB132	>= 1 saturated or aromatic nitrogen-containing ring size 4
0.0984	SUB130	>= 1 any ring size 4
0.0288	SUB133	>= 1 saturated or aromatic heteroatom-containing ring size 4
PF07885	Ion channel
0.4761	SUB683	O-C-C-C-C-N
0.4297	SUB547	N-C:C-[#1]
0.3671	SUB503	N-C=C-[#1]
0.2880	SUB785	OC1CCC(N)CC1
0.0560	SUB459	S(-O)(=O)
0.0521	SUB668	C=C-C-O-[#1]
0.0118	SUB306	N-S
PF02781	Glucose-6-phosphate dehydrogenase, C-terminal domain
0.4750	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1015	SUB568	O-C-C-O
0.0891	SUB572	[#1]-C-O-[#1]
0.0640	SUB664	O-C-C-O-[#1]
0.0032	SUB444	C(-C)(=O)
0.0001	SUB32	>= 2 P
0.0001	SUB389	C(:C)(:N)(:N)
PF03137	Organic Anion Transporter Polypeptide (OATP),  family
0.4740	SUB4	>= 32 H
0.3774	SUB615	C-C-O-C-C
0.1445	SUB777	CC1CCC(C)CC1
0.1311	SUB712	C-C(C)(C)-C-C
0.0706	SUB200	>= 4 any ring size 6
0.0306	SUB335	C(~C)(~C)(~C)(~C)
PF01835	MG2 domain
0.4729	SUB23	>= 16 O
PF03630	Fumble 
0.4720	SUB38	>= 1 Cl
0.3277	SUB592	Cl-C-C-C-C
0.0353	SUB363	C(~Cl)(:C)
PF00005	ABC transporter
0.4717	SUB3	>= 16 H
0.4624	SUB691	O-C-C-C-C-C-O
0.4623	SUB336	C(~C)(~C)(~C)(~H)
0.4495	SUB66	>= 1 As
0.4425	SUB757	Cc1c(O)cccc1
0.4384	SUB779	CC1CCC(S)CC1
0.3520	SUB646	O=C-N-C-C
0.3410	SUB716	Cc1ccc(S)cc1
0.3251	SUB261	>= 3 hetero-aromatic rings
0.2890	SUB540	N=C-C-[#1]
0.2870	SUB505	N:C:N-C
0.2669	SUB582	O=C-C-C-O
0.2376	SUB699	O-C-C-C-C-C-C-C
0.2270	SUB688	O=C-C-C-C=O
0.2122	SUB378	C(~N)(:C)(:C)
0.1871	SUB813	NC1CC(N)CCC1
0.1852	SUB417	C=C
0.1635	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.1596	SUB759	Cc1c(N)cccc1
0.1548	SUB442	C(-C)(=C)
0.1516	SUB698	C-C-C-C-C-C(C)-C
0.1438	SUB432	C(-C)(-C)(=N)
0.1230	SUB567	O-C-C-N
0.1112	SUB385	C(:C)(:C)
0.1109	SUB17	>= 4 N
0.1029	SUB193	>= 3 any ring size 6
0.1021	SUB622	N-C:C:C:N
0.0962	SUB541	C-N-C-[#1]
0.0875	SUB672	O=C-C=C-C
0.0618	SUB643	O-C-C-C=O
0.0517	SUB629	C-N-C-C:C
0.0485	SUB387	C(:C)(:C)(:N)
0.0478	SUB381	C(~O)(~O)
0.0460	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.0427	SUB543	O-C:C-[#1]
0.0387	SUB658	C-N-C:C-C
0.0381	SUB694	O=C-C-C-C-C-O
0.0361	SUB660	O-C-C-N-C
0.0334	SUB346	C(~C)(~H)(~N)
0.0309	SUB259	>= 2 hetero-aromatic rings
0.0300	SUB529	[#1]-N-C-[#1]
0.0276	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0203	SUB647	O=C-N-C-[#1]
0.0163	SUB706	O=C-C-C-C-C(O)-C
0.0134	SUB777	CC1CCC(C)CC1
0.0034	SUB140	>= 2 saturated or aromatic heteroatom-containing ring size 4
0.0019	SUB137	>= 2 any ring size 4
0.0006	SUB572	[#1]-C-O-[#1]
PF00361	NADH-Ubiquinone/plastoquinone (complex I), , various chains
0.4698	SUB32	>= 2 P
0.3069	SUB389	C(:C)(:N)(:N)
0.2015	SUB398	N(~C)(:C)(:C)
0.1801	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1441	SUB158	>= 3 any ring size 5
PF00003	7 transmembrane sweet-taste receptor of 3 GCPR
0.4673	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.1814	SUB697	C-C-C-C-C-C-C-C
0.1429	SUB529	[#1]-N-C-[#1]
0.0962	SUB517	[#1]-C=C-[#1]
0.0798	SUB683	O-C-C-C-C-N
0.0616	SUB665	C-C=C-C=C
0.0537	SUB644	[#1]-C-C-N-[#1]
0.0258	SUB409	O(~H)(~S)
PF00145	C-5 cytosine-specific DNA methylase
0.4672	SUB287	C-O
0.2550	SUB572	[#1]-C-O-[#1]
0.1485	SUB392	N(~C)(~C)(~C)
0.0242	SUB529	[#1]-N-C-[#1]
PF00645	Poly(ADP-ribose),  polymerase and DNA-Ligase Zn-finger region
0.4670	SUB624	O=C-C:C-C
0.1181	SUB673	O=C-C=C-[#1]
0.0715	SUB540	N=C-C-[#1]
0.0492	SUB440	C(-C)(-N)(=O)
0.0198	SUB581	O=C-C-C-N
PF02055	O-Glycosyl hydrolase family 30
0.4669	SUB702	O-C-C-C-C-C(O)-C
0.1716	SUB640	O-C-C-C-O
PF07703	Alpha-2-macroglobulin family N-terminal region
0.4666	SUB23	>= 16 O
PF01596	O-methyltransferase
0.4654	SUB545	O-C:C-O
0.4395	SUB825	OC1C(O)CCCC1
0.3610	SUB632	O-C:C-O-[#1]
0.2181	SUB762	Oc1c(O)cccc1
PF08491	Squalene epoxidase
0.4627	SUB250	>= 1 saturated or aromatic carbon-only ring size 10
0.2695	SUB386	C(:C)(:C)(:C)
0.0753	SUB735	Cc1cc(C)ccc1
PF08534	Redoxin
0.4622	SUB680	C-C-C-C-C-C
0.0980	SUB179	>= 1 any ring size 6
PF00104	Ligand-binding domain of nuclear hormone receptor
0.4622	SUB712	C-C(C)(C)-C-C
0.4383	SUB706	O=C-C-C-C-C(O)-C
0.3267	SUB533	S-C:C-[#1]
0.2664	SUB13	>= 16 C
0.1989	SUB467	N#C-C=C
0.1756	SUB672	O=C-C=C-C
0.1691	SUB629	C-N-C-C:C
0.1377	SUB738	Cc1cc(N)ccc1
0.1202	SUB714	Cc1ccc(C)cc1
0.1186	SUB375	C(~H)(~H)(~H)
0.1140	SUB482	O-S-C:C
0.0931	SUB687	O=C-C-C-C-O
0.0846	SUB735	Cc1cc(C)ccc1
0.0806	SUB14	>= 32 C
0.0790	SUB677	N#C-C-C-C
0.0750	SUB600	[#1]-C-C=C-[#1]
0.0622	SUB201	>= 4 saturated or aromatic carbon-only ring size 6
0.0599	SUB517	[#1]-C=C-[#1]
0.0548	SUB522	C:N-C-[#1]
0.0454	SUB554	O=C-C=C
0.0414	SUB703	O-C-C-C-C-C-N-C
0.0410	SUB682	O-C-C-C-C-O
0.0409	SUB821	CC1C(S)CCCC1
0.0394	SUB779	CC1CCC(S)CC1
0.0321	SUB441	C(-C)(-O)(=O)
0.0283	SUB461	C-C-C#C
0.0220	SUB674	O=C-C=C-N
0.0188	SUB448	C(-H)(=N)
0.0101	SUB679	C-C-C=C-C
0.0081	SUB694	O=C-C-C-C-C-O
0.0016	SUB446	C(-H)(-N)(=C)
0.0011	SUB646	O=C-N-C-C
0.0010	SUB66	>= 1 As
0.0010	SUB525	C-C=C-C
0.0007	SUB661	C-C=C-C-C
0.0001	SUB392	N(~C)(~C)(~C)
PF01347	Lipoprotein amino terminal region
0.4598	SUB702	O-C-C-C-C-C(O)-C
0.4357	SUB624	O=C-C:C-C
0.2841	SUB706	O=C-C-C-C-C(O)-C
0.1053	SUB691	O-C-C-C-C-C-O
PF00058	Low-density lipoprotein receptor repeat class B
0.4595	SUB381	C(~O)(~O)
0.2572	SUB681	O-C-C-C-C-C
0.0649	SUB696	O=C-C-C-C-C-N
PF02394	Interleukin-1 propeptide
0.4578	SUB801	CC1CC(N)CCC1
0.3164	SUB738	Cc1cc(N)ccc1
PF00431	CUB domain
0.4577	SUB337	C(~C)(~C)(~C)(~N)
PF00092	von Willebrand factor type A domain
0.4563	SUB441	C(-C)(-O)(=O)
0.2537	SUB705	O=C-C-C-C-C-C-C
0.1384	SUB34	>= 1 S
0.0939	SUB704	O-C-C-C-C-C(N)-C
0.0810	SUB698	C-C-C-C-C-C(C)-C
0.0658	SUB378	C(~N)(:C)(:C)
0.0609	SUB20	>= 2 O
0.0415	SUB250	>= 1 saturated or aromatic carbon-only ring size 10
0.0392	SUB697	C-C-C-C-C-C-C-C
0.0377	SUB460	S(=O)(=O)
0.0322	SUB438	C(-C)(-N)(=C)
0.0218	SUB708	O=C-C-C-C-C(N)-C
0.0128	SUB394	N(~C)(~H)
0.0124	SUB300	N-H
PF00041	Fibronectin type III domain
0.4561	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.3116	SUB407	O(~C)(~H)
0.2566	SUB368	C(~H)(~O)(~O)
0.2085	SUB602	N-C:C:C-N
0.2056	SUB375	C(~H)(~H)(~H)
0.0907	SUB348	C(~C)(~H)(~O)(~O)
0.0771	SUB662	O-C-O-C-C
0.0583	SUB663	O-C-C-O-C
0.0399	SUB360	C(~C)(:N)(:N)
0.0385	SUB572	[#1]-C-O-[#1]
0.0110	SUB296	C-As
0.0101	SUB509	S=C-N-C
0.0002	SUB512	S=C-N-[#1]
PF00490	Delta-aminolevulinic acid dehydratase
0.4548	SUB696	O=C-C-C-C-C-N
0.2560	SUB618	C-C-C-O-[#1]
PF12179	I-kappa-kinase-beta NEMO binding domain
0.4538	SUB349	C(~C)(~H)(~P)
0.3882	SUB95	>= 1 Au
0.2949	SUB324	P-H
0.1661	SUB411	P(~C)(~C)
PF05089	Alpha-N-acetylglucosaminidase (NAGLU), 
0.4536	SUB348	C(~C)(~H)(~O)(~O)
0.0464	SUB368	C(~H)(~O)(~O)
PF02793	Hormone receptor domain
0.4534	SUB23	>= 16 O
0.2193	SUB695	O=C-C-C-C-C=O
0.1710	SUB489	N-C=N-[#1]
0.1178	SUB18	>= 8 N
PF02310	B12 binding domain
0.4533	SUB708	O=C-C-C-C-C(N)-C
0.3003	SUB520	N=C-N-C
0.2536	SUB691	O-C-C-C-C-C-O
0.2297	SUB717	Cc1ccc(N)cc1
0.1003	SUB801	CC1CC(N)CCC1
0.0829	SUB683	O-C-C-C-C-N
0.0478	SUB686	O=C-C-C-C-N
0.0408	SUB339	C(~C)(~C)(~H)(~N)
0.0002	SUB18	>= 8 N
0.0002	SUB172	>= 5 any ring size 5
0.0001	SUB60	>= 1 Co
PF01731	Arylesterase
0.4531	SUB581	O=C-C-C-N
0.3738	SUB522	C:N-C-[#1]
0.1748	SUB441	C(-C)(-O)(=O)
0.0760	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
PF00180	Isocitrate/isopropylmalate dehydrogenase
0.4516	SUB691	O-C-C-C-C-C-O
0.3421	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.3038	SUB158	>= 3 any ring size 5
0.2183	SUB580	O=C-C-C-C
0.1901	SUB664	O-C-C-O-[#1]
0.0233	SUB695	O=C-C-C-C-C=O
PF00278	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
0.4509	SUB588	N-C:C-O-[#1]
0.1870	SUB17	>= 4 N
0.1252	SUB692	O-C-C-C-C-C-N
PF02932	Neurotransmitter-gated ion-channel transmembrane region
0.4508	SUB207	>= 5 any ring size 6
0.3859	SUB228	>= 1 any ring size 8
0.2995	SUB229	>= 1 saturated or aromatic carbon-only ring size 8
0.2807	SUB730	Nc1ccc(Cl)cc1
0.2636	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.2467	SUB686	O=C-C-C-C-N
0.2442	SUB825	OC1C(O)CCCC1
0.2426	SUB214	>= 1 any ring size 7
0.2168	SUB14	>= 32 C
0.1979	SUB598	O=C-C-C:C
0.1950	SUB345	C(~C)(~H)
0.1715	SUB16	>= 2 N
0.1622	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.1619	SUB709	C-C(C)-C-C
0.1609	SUB738	Cc1cc(N)ccc1
0.1600	SUB840	CC1CC(C)CC1
0.1552	SUB780	CC1CCC(N)CC1
0.1537	SUB591	C-C:C-O-[#1]
0.1510	SUB288	C-F
0.1362	SUB353	C(~C)(~O)
0.1323	SUB366	C(~H)(~N)
0.1287	SUB634	N-C-C:C-C
0.1261	SUB640	O-C-C-C-O
0.1258	SUB577	N=C-C:C-[#1]
0.1107	SUB486	N:C:C:N
0.1019	SUB392	N(~C)(~C)(~C)
0.0922	SUB637	C-N-C-N-C
0.0898	SUB615	C-C-O-C-C
0.0876	SUB739	Cc1cc(Cl)ccc1
0.0796	SUB375	C(~H)(~H)(~H)
0.0781	SUB151	>= 2 any ring size 5
0.0769	SUB341	C(~C)(~C)(~N)
0.0719	SUB793	NC1CCC(Cl)CC1
0.0637	SUB802	CC1CC(Cl)CCC1
0.0614	SUB616	N-C-C-O-C
0.0585	SUB574	O-C-C=C
0.0562	SUB696	O=C-C-C-C-C-N
0.0529	SUB346	C(~C)(~H)(~N)
0.0467	SUB461	C-C-C#C
0.0445	SUB537	O=C-C-N
0.0423	SUB38	>= 1 Cl
0.0412	SUB757	Cc1c(O)cccc1
0.0405	SUB517	[#1]-C=C-[#1]
0.0337	SUB342	C(~C)(~C)(~O)
0.0302	SUB251	>= 1 saturated or aromatic nitrogen-containing ring size 10
0.0278	SUB710	C-C(C)-C-C-C
0.0272	SUB453	C(-O)(=O)
0.0215	SUB712	C-C(C)(C)-C-C
0.0174	SUB398	N(~C)(:C)(:C)
0.0141	SUB801	CC1CC(N)CCC1
0.0080	SUB201	>= 4 saturated or aromatic carbon-only ring size 6
0.0052	SUB339	C(~C)(~C)(~H)(~N)
0.0044	SUB680	C-C-C-C-C-C
0.0021	SUB594	N-C-C-C-N
0.0007	SUB701	O-C-C-C-C-C-O-C
0.0007	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.0004	SUB772	Nc1c(Cl)cccc1
0.0003	SUB581	O=C-C-C-N
PF05995	Cysteine dioxygenase type I
0.4506	SUB414	S(~C)(~H)
0.1809	SUB567	O-C-C-N
0.1239	SUB500	N-C:C:N
0.1093	SUB486	N:C:C:N
0.0859	SUB548	N-C:C-N
0.0566	SUB350	C(~C)(~H)(~S)
PF00230	Major intrinsic protein
0.4503	SUB458	S(-C)(=O)
0.0497	SUB459	S(-O)(=O)
PF01607	Chitin binding Peritrophin-A domain
0.4498	SUB572	[#1]-C-O-[#1]
0.3437	SUB683	O-C-C-C-C-N
0.0003	SUB18	>= 8 N
PF03002	Somatostatin/Cortistatin family
0.4497	SUB160	>= 3 saturated or aromatic nitrogen-containing ring size 5
0.4370	SUB414	S(~C)(~H)
0.3978	SUB332	C(~Br)(:N)
0.1575	SUB560	O-C-N-[#1]
0.1378	SUB738	Cc1cc(N)ccc1
0.0630	SUB644	[#1]-C-C-N-[#1]
PF00413	Matrixin
0.4486	SUB698	C-C-C-C-C-C(C)-C
0.3389	SUB21	>= 4 O
0.2534	SUB444	C(-C)(=O)
0.1743	SUB686	O=C-C-C-C-N
0.1328	SUB690	O-C-C-C-C-C-C
0.1195	SUB709	C-C(C)-C-C
0.0704	SUB603	O=C-C-N-C
0.0434	SUB517	[#1]-C=C-[#1]
0.0291	SUB580	O=C-C-C-C
0.0245	SUB372	C(~H)(:C)(:C)
0.0245	SUB642	O-C-C-C=C
0.0094	SUB681	O-C-C-C-C-C
PF00930	Dipeptidyl peptidase IV (DPP IV),  N-terminal region
0.4479	SUB702	O-C-C-C-C-C(O)-C
0.3354	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.3016	SUB529	[#1]-N-C-[#1]
0.2778	SUB2	>= 8 H
0.2085	SUB360	C(~C)(:N)(:N)
0.1411	SUB353	C(~C)(~O)
PF00201	UDP-glucoronosyl and UDP-glucosyl transferase
0.4474	SUB456	N(-O)(=O)
0.2370	SUB729	Nc1ccc(N)cc1
0.1893	SUB792	NC1CCC(N)CC1
0.0794	SUB402	N(~O)(~O)
PF12605	Casein kinase 1 gamma C terminal
0.4473	SUB299	C-I
0.0020	SUB398	N(~C)(:C)(:C)
0.0001	SUB47	>= 1 I
PF00670	S-adenosyl-L-homocysteine hydrolase, NAD binding domain
0.4459	SUB572	[#1]-C-O-[#1]
0.0683	SUB622	N-C:C:C:N
0.0379	SUB389	C(:C)(:N)(:N)
0.0311	SUB602	N-C:C:C-N
PF01459	Eukaryotic porin
0.4438	SUB313	O-Al
0.3896	SUB52	>= 1 Al
PF02259	FAT domain
0.4432	SUB189	>= 2 saturated or aromatic heteroatom-containing ring size 6
0.0229	SUB433	C(-C)(-C)(=O)
PF00117	Glutamine amidotransferase class-I
0.4431	SUB529	[#1]-N-C-[#1]
0.1536	SUB341	C(~C)(~C)(~N)
0.1418	SUB695	O=C-C-C-C-C=O
PF01530	Zinc finger, C2HC type
0.4430	SUB459	S(-O)(=O)
PF00806	Pumilio-family RNA binding repeat
0.4413	SUB414	S(~C)(~H)
PF02254	TrkA-N domain
0.4389	SUB249	>= 1 any ring size 10
0.2018	SUB814	NC1CC(Cl)CCC1
0.0908	SUB295	C-Cl
0.0875	SUB586	C-C:C-N-C
0.0437	SUB343	C(~C)(~Cl)
0.0234	SUB658	C-N-C:C-C
0.0125	SUB751	Nc1cc(Cl)ccc1
PF00202	Aminotransferase class-III
0.4385	SUB444	C(-C)(=O)
0.1948	SUB421	C=O
0.1821	SUB407	O(~C)(~H)
0.1667	SUB536	O=C-C-C
0.0730	SUB686	O=C-C-C-C-N
0.0605	SUB580	O=C-C-C-C
0.0500	SUB685	O=C-C-C-C-C
0.0449	SUB639	O-C-C-C-N
PF03770	Inositol polyphosphate kinase 
0.4384	SUB31	>= 1 P
0.1712	SUB315	O-P
0.1006	SUB412	P(~O)(~O)
0.0962	SUB426	P=O
PF02888	Calmodulin binding domain
0.4380	SUB295	C-Cl
PF01082	Copper type II ascorbate-dependent monooxygenase, N-terminal domain
0.4370	SUB664	O-C-C-O-[#1]
0.2948	SUB499	O-C=C-C
PF09781	NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
0.4365	SUB486	N:C:C:N
0.0635	SUB548	N-C:C-N
PF02142	MGS-like domain
0.4342	SUB674	O=C-C=C-N
PF05347	Complex 1 protein (LYR family), 
0.4337	SUB32	>= 2 P
0.2180	SUB389	C(:C)(:N)(:N)
0.2062	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1491	SUB158	>= 3 any ring size 5
0.0364	SUB387	C(:C)(:C)(:N)
PF00763	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
0.4323	SUB674	O=C-C=C-N
0.2475	SUB691	O-C-C-C-C-C-O
0.0176	SUB594	N-C-C-C-N
PF00122	E1-E2 ATPase
0.4321	SUB406	O(~C)(~C)
0.1795	SUB22	>= 8 O
0.1232	SUB200	>= 4 any ring size 6
0.1026	SUB375	C(~H)(~H)(~H)
0.0985	SUB441	C(-C)(-O)(=O)
0.0509	SUB189	>= 2 saturated or aromatic heteroatom-containing ring size 6
0.0473	SUB140	>= 2 saturated or aromatic heteroatom-containing ring size 4
0.0217	SUB66	>= 1 As
0.0129	SUB137	>= 2 any ring size 4
0.0031	SUB51	>= 1 Mg
0.0001	SUB298	C-Br
PF02931	Neurotransmitter-gated ion-channel ligand binding domain
0.4308	SUB207	>= 5 any ring size 6
0.4277	SUB589	O=C-C-C=O
0.2717	SUB214	>= 1 any ring size 7
0.2591	SUB772	Nc1c(Cl)cccc1
0.2207	SUB577	N=C-C:C-[#1]
0.2123	SUB366	C(~H)(~N)
0.2118	SUB780	CC1CCC(N)CC1
0.2038	SUB345	C(~C)(~H)
0.2031	SUB840	CC1CC(C)CC1
0.1935	SUB16	>= 2 N
0.1928	SUB598	O=C-C-C:C
0.1864	SUB228	>= 1 any ring size 8
0.1835	SUB392	N(~C)(~C)(~C)
0.1829	SUB288	C-F
0.1738	SUB804	OC1CC(O)CCC1
0.1708	SUB712	C-C(C)(C)-C-C
0.1584	SUB709	C-C(C)-C-C
0.1582	SUB686	O=C-C-C-C-N
0.1549	SUB591	C-C:C-O-[#1]
0.1530	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.1474	SUB486	N:C:C:N
0.1466	SUB151	>= 2 any ring size 5
0.1394	SUB640	O-C-C-C-O
0.1305	SUB537	O=C-C-N
0.1290	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.1258	SUB353	C(~C)(~O)
0.1129	SUB680	C-C-C-C-C-C
0.1120	SUB616	N-C-C-O-C
0.1112	SUB14	>= 32 C
0.1075	SUB793	NC1CCC(Cl)CC1
0.1062	SUB346	C(~C)(~H)(~N)
0.1020	SUB341	C(~C)(~C)(~N)
0.0976	SUB574	O-C-C=C
0.0933	SUB581	O=C-C-C-N
0.0914	SUB517	[#1]-C=C-[#1]
0.0766	SUB801	CC1CC(N)CCC1
0.0748	SUB710	C-C(C)-C-C-C
0.0699	SUB637	C-N-C-N-C
0.0688	SUB757	Cc1c(O)cccc1
0.0625	SUB461	C-C-C#C
0.0483	SUB696	O=C-C-C-C-C-N
0.0423	SUB229	>= 1 saturated or aromatic carbon-only ring size 8
0.0353	SUB701	O-C-C-C-C-C-O-C
0.0349	SUB375	C(~H)(~H)(~H)
0.0255	SUB342	C(~C)(~C)(~O)
0.0240	SUB251	>= 1 saturated or aromatic nitrogen-containing ring size 10
0.0192	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.0171	SUB730	Nc1ccc(Cl)cc1
0.0114	SUB594	N-C-C-C-N
0.0056	SUB339	C(~C)(~C)(~H)(~N)
0.0056	SUB739	Cc1cc(Cl)ccc1
0.0043	SUB802	CC1CC(Cl)CCC1
0.0017	SUB540	N=C-C-[#1]
0.0004	SUB615	C-C-O-C-C
0.0002	SUB825	OC1C(O)CCCC1
PF06387	D1 dopamine receptor-interacting protein (calcyon), 
0.4304	SUB193	>= 3 any ring size 6
0.2804	SUB392	N(~C)(~C)(~C)
0.1756	SUB252	>= 1 saturated or aromatic heteroatom-containing ring size 10
PF00212	Atrial natriuretic peptide
0.4282	SUB242	>= 1 any ring size 9
0.2286	SUB572	[#1]-C-O-[#1]
0.1118	SUB261	>= 3 hetero-aromatic rings
PF00040	Fibronectin type II domain
0.4272	SUB704	O-C-C-C-C-C(N)-C
0.3850	SUB639	O-C-C-C-N
0.1936	SUB339	C(~C)(~C)(~H)(~N)
0.0597	SUB756	Cc1c(C)cccc1
0.0479	SUB335	C(~C)(~C)(~C)(~C)
PF03098	Animal haem peroxidase
0.4265	SUB447	C(-H)(=C)
0.2675	SUB20	>= 2 O
0.2495	SUB478	N-N-C:C
0.2433	SUB512	S=C-N-[#1]
0.2096	SUB228	>= 1 any ring size 8
0.1926	SUB503	N-C=C-[#1]
0.1838	SUB517	[#1]-C=C-[#1]
0.1800	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.1793	SUB186	>= 2 any ring size 6
0.1429	SUB459	S(-O)(=O)
0.1323	SUB309	O-H
0.1227	SUB450	C(-N)(=C)
0.0927	SUB574	O-C-C=C
0.0900	SUB441	C(-C)(-O)(=O)
0.0870	SUB756	Cc1c(C)cccc1
0.0865	SUB735	Cc1cc(C)ccc1
0.0782	SUB460	S(=O)(=O)
0.0770	SUB642	O-C-C-C=C
0.0381	SUB589	O=C-C-C=O
0.0368	SUB556	N=C-C=C
0.0344	SUB620	O-C-C=C-C
0.0326	SUB438	C(-C)(-N)(=C)
0.0308	SUB598	O=C-C-C:C
0.0287	SUB433	C(-C)(-C)(=O)
0.0239	SUB453	C(-O)(=O)
0.0179	SUB501	C-S-C:C
0.0119	SUB458	S(-C)(=O)
0.0112	SUB396	N(~C)(~O)
0.0097	SUB610	Cl-C-C-N-C
0.0030	SUB415	S(~C)(~O)
0.0020	SUB499	O-C=C-C
PF01564	Spermine/spermidine synthase
0.4248	SUB594	N-C-C-C-N
0.1908	SUB529	[#1]-N-C-[#1]
0.1056	SUB17	>= 4 N
0.0363	SUB659	C-C-S-C-C
PF02100	Ornithine decarboxylase antizyme
0.4232	SUB696	O=C-C-C-C-C-N
0.1400	SUB692	O-C-C-C-C-C-N
0.1142	SUB441	C(-C)(-O)(=O)
0.0489	SUB537	O=C-C-N
PF00389	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
0.4229	SUB389	C(:C)(:N)(:N)
0.1500	SUB158	>= 3 any ring size 5
0.0661	SUB444	C(-C)(=O)
0.0584	SUB421	C=O
0.0584	SUB360	C(~C)(:N)(:N)
PF00090	Thrombospondin type 1 domain
0.4227	SUB368	C(~H)(~O)(~O)
0.1246	SUB702	O-C-C-C-C-C(O)-C
PF00059	Lectin C-type domain
0.4217	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.2715	SUB693	O=C-C-C-C-C-C
0.2418	SUB350	C(~C)(~H)(~S)
0.2130	SUB406	O(~C)(~C)
0.2083	SUB367	C(~H)(~O)
0.1946	SUB514	S:C:C-[#1]
0.1566	SUB572	[#1]-C-O-[#1]
0.1155	SUB393	N(~C)(~C)(~H)
0.1111	SUB616	N-C-C-O-C
0.1095	SUB564	O-C-O-C
0.0007	SUB472	S:C:C:C
PF00491	Arginase family
0.4192	SUB692	O-C-C-C-C-C-N
0.2692	SUB696	O=C-C-C-C-C-N
0.0577	SUB537	O=C-C-N
PF00452	Apoptosis regulator proteins, Bcl-2 family
0.4179	SUB629	C-N-C-C:C
0.2103	SUB639	O-C-C-C-N
0.1282	SUB130	>= 1 any ring size 4
0.0864	SUB713	C-C(C)-C(C)-C
0.0189	SUB799	CC1CC(O)CCC1
0.0139	SUB700	O-C-C-C-C-C(C)-C
0.0087	SUB640	O-C-C-C-O
0.0043	SUB260	>= 3 aromatic rings
PF05378	Hydantoinase/oxoprolinase N-terminal region
0.4173	SUB694	O=C-C-C-C-C-O
PF01593	Flavin containing amine oxidoreductase
0.4168	SUB431	C(-C)(-C)(=C)
0.3854	SUB12	>= 8 C
0.3154	SUB581	O=C-C-C-N
0.2914	SUB689	C-C-C-C-C-C-C
0.1787	SUB394	N(~C)(~H)
0.1448	SUB200	>= 4 any ring size 6
0.1021	SUB697	C-C-C-C-C-C-C-C
0.0865	SUB529	[#1]-N-C-[#1]
0.0216	SUB756	Cc1c(C)cccc1
0.0155	SUB644	[#1]-C-C-N-[#1]
PF00989	PAS fold
0.4152	SUB386	C(:C)(:C)(:C)
0.2740	SUB621	C:C-O-C-C
0.2605	SUB529	[#1]-N-C-[#1]
0.2509	SUB24	>= 1 F
0.2290	SUB642	O-C-C-C=C
0.1227	SUB639	O-C-C-C-N
0.1043	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0689	SUB739	Cc1cc(Cl)ccc1
0.0543	SUB288	C-F
0.0196	SUB262	>= 4 aromatic rings
0.0018	SUB802	CC1CC(Cl)CCC1
PF03720	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain
0.4151	SUB32	>= 2 P
PF00754	F5/8 type C domain
0.4144	SUB813	NC1CC(N)CCC1
0.2535	SUB96	>= 1 Hg
0.2040	SUB717	Cc1ccc(N)cc1
0.1198	SUB750	Nc1cc(N)ccc1
0.0822	SUB714	Cc1ccc(C)cc1
0.0520	SUB195	>= 3 saturated or aromatic nitrogen-containing ring size 6
0.0019	SUB780	CC1CCC(N)CC1
PF00420	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
0.4143	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.3071	SUB158	>= 3 any ring size 5
PF08399	VWA N-terminal
0.4142	SUB460	S(=O)(=O)
0.0736	SUB697	C-C-C-C-C-C-C-C
0.0001	SUB683	O-C-C-C-C-N
PF01323	DSBA-like thioredoxin domain
0.4139	SUB686	O=C-C-C-C-N
0.2130	SUB350	C(~C)(~H)(~S)
0.0612	SUB703	O-C-C-C-C-C-N-C
PF01462	Leucine rich repeat N-terminal domain
0.4135	SUB336	C(~C)(~C)(~C)(~H)
0.2092	SUB572	[#1]-C-O-[#1]
0.1685	SUB203	>= 4 saturated or aromatic heteroatom-containing ring size 6
0.1501	SUB340	C(~C)(~C)(~H)(~O)
0.1373	SUB543	O-C:C-[#1]
0.0769	SUB195	>= 3 saturated or aromatic nitrogen-containing ring size 6
0.0002	SUB202	>= 4 saturated or aromatic nitrogen-containing ring size 6
PF04711	Apolipoprotein A-II (ApoA-II), 
0.4132	SUB348	C(~C)(~H)(~O)(~O)
0.0154	SUB611	C-O-C-O-C
0.0067	SUB564	O-C-O-C
0.0040	SUB662	O-C-O-C-C
0.0033	SUB701	O-C-C-C-C-C-O-C
0.0014	SUB702	O-C-C-C-C-C(O)-C
PF04055	Radical SAM superfamily
0.4125	SUB35	>= 2 S
PF02466	Tim17/Tim22/Tim23 family
0.4083	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0327	SUB158	>= 3 any ring size 5
PF02934	GatB/GatE catalytic domain
0.4049	SUB695	O=C-C-C-C-C=O
0.1217	SUB686	O=C-C-C-C-N
0.0197	SUB694	O=C-C-C-C-C-O
PF00329	Respiratory-chain NADH dehydrogenase, 30 Kd subunit
0.4049	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0704	SUB446	C(-H)(-N)(=C)
PF00858	Amiloride-sensitive sodium channel
0.4020	SUB486	N:C:C:N
0.3614	SUB379	C(~N)(:C)(:N)
0.3261	SUB578	C:C-N-C:C
PF01571	Aminomethyltransferase folate-binding domain
0.4005	SUB691	O-C-C-C-C-C-O
0.1601	SUB488	N-C=N-C
0.1329	SUB673	O=C-C=C-[#1]
0.0888	SUB780	CC1CCC(N)CC1
0.0655	SUB683	O-C-C-C-C-N
0.0464	SUB717	Cc1ccc(N)cc1
0.0297	SUB708	O=C-C-C-C-C(N)-C
0.0166	SUB594	N-C-C-C-N
0.0076	SUB32	>= 2 P
PF00682	HMGL-like
0.3983	SUB441	C(-C)(-O)(=O)
0.1012	SUB695	O=C-C-C-C-C=O
0.0004	SUB453	C(-O)(=O)
PF02826	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
0.3982	SUB389	C(:C)(:N)(:N)
0.0893	SUB444	C(-C)(=O)
PF00151	Lipase
0.3980	SUB603	O=C-C-N-C
0.3833	SUB441	C(-C)(-O)(=O)
0.0968	SUB342	C(~C)(~C)(~O)
PF11956	Ankyrin-G binding motif of KCNQ2-3
0.3962	SUB756	Cc1c(C)cccc1
PF05071	NADH ubiquinone oxidoreductase subunit NDUFA12
0.3939	SUB158	>= 3 any ring size 5
0.1912	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF00337	Galactoside-binding lectin
0.3907	SUB348	C(~C)(~H)(~O)(~O)
0.2838	SUB440	C(-C)(-N)(=O)
0.2479	SUB406	O(~C)(~C)
0.2283	SUB692	O-C-C-C-C-C-N
0.1847	SUB96	>= 1 Hg
0.1839	SUB680	C-C-C-C-C-C
0.1702	SUB672	O=C-C=C-C
0.0651	SUB11	>= 4 C
0.0477	SUB20	>= 2 O
0.0209	SUB333	C(~C)(~C)
0.0006	SUB482	O-S-C:C
PF00045	Hemopexin
0.3891	SUB345	C(~C)(~H)
0.2604	SUB533	S-C:C-[#1]
0.1756	SUB492	C-N:C-[#1]
0.1426	SUB440	C(-C)(-N)(=O)
0.1330	SUB515	O-N-C-C
0.1249	SUB193	>= 3 any ring size 6
0.1174	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.1171	SUB336	C(~C)(~C)(~C)(~H)
0.0973	SUB466	O=S-C-C
0.0905	SUB369	C(~H)(~S)
0.0899	SUB603	O=C-C-N-C
0.0743	SUB537	O=C-C-N
0.0645	SUB452	C(-N)(=O)
0.0553	SUB700	O-C-C-C-C-C(C)-C
0.0472	SUB709	C-C(C)-C-C
0.0396	SUB375	C(~H)(~H)(~H)
PF00489	Interleukin-6/G-CSF/MGF family
0.3885	SUB140	>= 2 saturated or aromatic heteroatom-containing ring size 4
0.1908	SUB713	C-C(C)-C(C)-C
0.1137	SUB13	>= 16 C
0.1115	SUB20	>= 2 O
0.0960	SUB375	C(~H)(~H)(~H)
PF00184	Neurohypophysial hormones, C-terminal Domain
0.3883	SUB18	>= 8 N
0.3538	SUB369	C(~H)(~S)
0.2835	SUB350	C(~C)(~H)(~S)
PF00070	Pyridine nucleotide-disulphide oxidoreductase
0.3878	SUB408	O(~C)(~P)
0.2844	SUB691	O-C-C-C-C-C-O
0.2554	SUB249	>= 1 any ring size 10
0.2367	SUB610	Cl-C-C-N-C
0.0935	SUB360	C(~C)(:N)(:N)
0.0923	SUB13	>= 16 C
0.0574	SUB414	S(~C)(~H)
0.0438	SUB389	C(:C)(:N)(:N)
0.0050	SUB369	C(~H)(~S)
0.0032	SUB350	C(~C)(~H)(~S)
PF00764	Arginosuccinate synthase
0.3871	SUB638	O-C-C-C-C
0.2262	SUB567	O-C-C-N
0.1207	SUB339	C(~C)(~C)(~H)(~N)
0.0577	SUB618	C-C-C-O-[#1]
0.0213	SUB692	O-C-C-C-C-C-N
PF00653	Inhibitor of Apoptosis domain
0.3859	SUB696	O=C-C-C-C-C-N
0.2613	SUB335	C(~C)(~C)(~C)(~C)
0.2457	SUB822	CC1C(N)CCCC1
0.1027	SUB603	O=C-C-N-C
0.0810	SUB712	C-C(C)(C)-C-C
0.0541	SUB4	>= 32 H
0.0266	SUB647	O=C-N-C-[#1]
PF04515	Plasma-membrane choline transporter
0.3856	SUB572	[#1]-C-O-[#1]
0.3767	SUB660	O-C-C-N-C
0.0266	SUB392	N(~C)(~C)(~C)
PF00568	WH1 domain
0.3848	SUB45	>= 2 Br
0.0067	SUB331	C(~Br)(:C)
PF01490	Transmembrane amino acid transporter protein
0.3845	SUB529	[#1]-N-C-[#1]
0.3238	SUB537	O=C-C-N
0.1252	SUB567	O-C-C-N
PF00822	PMP-22/EMP/MP20/Claudin family
0.3773	SUB459	S(-O)(=O)
0.2561	SUB657	C-C-N-C-C
0.2454	SUB21	>= 4 O
0.1120	SUB620	O-C-C=C-C
0.1057	SUB34	>= 1 S
0.1044	SUB674	O=C-C=C-N
0.0797	SUB574	O-C-C=C
0.0630	SUB16	>= 2 N
0.0143	SUB438	C(-C)(-N)(=C)
0.0023	SUB460	S(=O)(=O)
0.0003	SUB378	C(~N)(:C)(:C)
PF07653	Variant SH3 domain
0.3764	SUB572	[#1]-C-O-[#1]
PF01426	BAH domain
0.3759	SUB708	O=C-C-C-C-C(N)-C
0.0103	SUB452	C(-N)(=O)
PF00692	dUTPase
0.3743	SUB648	O=C-N-C-N
0.0217	SUB31	>= 1 P
0.0185	SUB412	P(~O)(~O)
0.0111	SUB32	>= 2 P
0.0058	SUB315	O-P
0.0044	SUB408	O(~C)(~P)
PF02060	Slow voltage-gated potassium channel
0.3742	SUB769	Sc1c(Cl)cccc1
0.1258	SUB822	CC1C(N)CCCC1
PF00243	Nerve growth factor family
0.3740	SUB802	CC1CC(Cl)CCC1
0.1973	SUB337	C(~C)(~C)(~C)(~N)
PF04622	ERG2 and Sigma1 receptor like protein
0.3724	SUB193	>= 3 any ring size 6
0.1878	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
0.1553	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.0347	SUB713	C-C(C)-C(C)-C
PF00084	Sushi domain (SCR repeat), 
0.3716	SUB343	C(~C)(~Cl)
0.2668	SUB369	C(~H)(~S)
0.2255	SUB640	O-C-C-C-O
0.1692	SUB704	O-C-C-C-C-C(N)-C
0.1453	SUB608	N-C-C-C:C
0.1309	SUB657	C-C-N-C-C
0.1252	SUB20	>= 2 O
0.1228	SUB340	C(~C)(~C)(~H)(~O)
0.0530	SUB347	C(~C)(~H)(~O)
0.0475	SUB441	C(-C)(-O)(=O)
0.0367	SUB717	Cc1ccc(N)cc1
0.0346	SUB708	O=C-C-C-C-C(N)-C
0.0265	SUB350	C(~C)(~H)(~S)
0.0018	SUB367	C(~H)(~O)
PF02784	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
0.3709	SUB498	O-C:C:N
0.2958	SUB17	>= 4 N
0.1264	SUB692	O-C-C-C-C-C-N
PF03073	TspO/MBR family
0.3689	SUB440	C(-C)(-N)(=O)
0.2218	SUB346	C(~C)(~H)(~N)
0.2127	SUB556	N=C-C=C
0.1714	SUB366	C(~H)(~N)
0.1631	SUB730	Nc1ccc(Cl)cc1
0.1593	SUB539	N=C-C-C
0.1448	SUB592	Cl-C-C-C-C
0.1068	SUB36	>= 4 S
0.0930	SUB454	N(-C)(=C)
0.0670	SUB577	N=C-C:C-[#1]
0.0398	SUB295	C-Cl
0.0225	SUB504	Cl-C:C-[#1]
0.0013	SUB38	>= 1 Cl
0.0005	SUB502	Cl-C:C-C
0.0003	SUB551	Cl-C-C-C
0.0001	SUB793	NC1CCC(Cl)CC1
PF00550	Phosphopantetheine attachment site
0.3687	SUB674	O=C-C=C-N
0.0702	SUB586	C-C:C-N-C
0.0462	SUB658	C-N-C:C-C
0.0302	SUB496	C-N-C:C
PF01127	Succinate dehydrogenase/Fumarate reductase transmembrane subunit
0.3661	SUB688	O=C-C-C-C=O
PF01625	Peptide methionine sulfoxide reductase
0.3638	SUB413	S(~C)(~C)
PF00689	Cation transporting ATPase, C-terminus
0.3636	SUB25	>= 2 F
0.2456	SUB39	>= 2 Cl
0.1777	SUB200	>= 4 any ring size 6
0.1541	SUB334	C(~C)(~C)(~C)
0.1514	SUB441	C(-C)(-O)(=O)
0.1508	SUB144	>= 1 any ring size 5
0.1367	SUB597	N=C-N-C-C
0.0841	SUB657	C-C-N-C-C
0.0776	SUB354	C(~C)(~S)
0.0723	SUB466	O=S-C-C
0.0680	SUB38	>= 1 Cl
0.0668	SUB612	N-C-C-N-C
0.0553	SUB189	>= 2 saturated or aromatic heteroatom-containing ring size 6
0.0484	SUB390	C(:N)(:N)
0.0287	SUB140	>= 2 saturated or aromatic heteroatom-containing ring size 4
0.0222	SUB137	>= 2 any ring size 4
0.0217	SUB180	>= 1 saturated or aromatic carbon-only ring size 6
0.0205	SUB375	C(~H)(~H)(~H)
0.0035	SUB51	>= 1 Mg
0.0024	SUB66	>= 1 As
0.0019	SUB298	C-Br
0.0001	SUB343	C(~C)(~Cl)
PF00454	Phosphatidylinositol 3- and 4-kinase
0.3634	SUB663	O-C-C-O-C
0.2863	SUB643	O-C-C-C=O
0.1733	SUB582	O=C-C-C-O
0.1237	SUB738	Cc1cc(N)ccc1
0.1035	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0724	SUB834	NC1C(N)CCCC1
0.0514	SUB646	O=C-N-C-C
0.0460	SUB537	O=C-C-N
0.0001	SUB771	Nc1c(N)cccc1
PF00591	Glycosyl transferase family, a/b domain
0.3631	SUB621	C:C-O-C-C
0.2510	SUB562	Cl-C-C=O
0.0313	SUB633	C-C-O-C:C
PF00757	Furin-like cysteine rich region
0.3629	SUB735	Cc1cc(C)ccc1
0.1812	SUB492	C-N:C-[#1]
0.1005	SUB374	C(~H)(:N)
0.0621	SUB637	C-N-C-N-C
0.0085	SUB390	C(:N)(:N)
0.0070	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0057	SUB621	C:C-O-C-C
0.0031	SUB615	C-C-O-C-C
0.0025	SUB485	N-C:N:C
0.0008	SUB683	O-C-C-C-C-N
PF02800	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
0.3620	SUB158	>= 3 any ring size 5
0.0472	SUB673	O=C-C=C-[#1]
0.0255	SUB389	C(:C)(:N)(:N)
0.0075	SUB602	N-C:C:C-N
PF01023	S-100/ICaBP type calcium binding domain
0.3619	SUB621	C:C-O-C-C
0.3353	SUB633	C-C-O-C:C
0.3132	SUB407	O(~C)(~H)
0.2999	SUB757	Cc1c(O)cccc1
0.1243	SUB580	O=C-C-C-C
0.1133	SUB700	O-C-C-C-C-C(C)-C
0.1060	SUB643	O-C-C-C=O
0.0985	SUB347	C(~C)(~H)(~O)
0.0420	SUB441	C(-C)(-O)(=O)
0.0372	SUB408	O(~C)(~P)
PF00135	Carboxylesterase
0.3616	SUB375	C(~H)(~H)(~H)
0.2906	SUB215	>= 1 saturated or aromatic carbon-only ring size 7
0.2272	SUB663	O-C-C-O-C
0.1911	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.1636	SUB822	CC1C(N)CCCC1
0.1625	SUB406	O(~C)(~C)
0.1562	SUB463	O-C-C=O
0.1142	SUB538	O=C-C-O
0.0910	SUB614	C-N-C-C-C
0.0430	SUB340	C(~C)(~C)(~H)(~O)
0.0225	SUB251	>= 1 saturated or aromatic nitrogen-containing ring size 10
PF01652	Eukaryotic initiation factor 4E
0.3596	SUB412	P(~O)(~O)
0.3487	SUB495	O=C-C:N
PF00962	Adenosine/AMP deaminase
0.3594	SUB500	N-C:C:N
0.3082	SUB548	N-C:C-N
0.2432	SUB379	C(~N)(:C)(:N)
0.0513	SUB486	N:C:C:N
0.0422	SUB387	C(:C)(:C)(:N)
PF01161	Phosphatidylethanolamine-binding protein
0.3575	SUB296	C-As
0.1425	SUB66	>= 1 As
PF08983	Domain of unknown function (DUF1856), 
0.3554	SUB14	>= 32 C
0.2272	SUB696	O=C-C-C-C-C-N
PF01230	HIT domain
0.3547	SUB691	O-C-C-C-C-C-O
0.3495	SUB640	O-C-C-C-O
PF00368	Hydroxymethylglutaryl-coenzyme A reductase
0.3537	SUB640	O-C-C-C-O
0.3156	SUB664	O-C-C-O-[#1]
0.2601	SUB643	O-C-C-C=O
0.2272	SUB618	C-C-C-O-[#1]
0.1464	SUB706	O=C-C-C-C-C(O)-C
0.1361	SUB629	C-N-C-C:C
0.1262	SUB572	[#1]-C-O-[#1]
0.1242	SUB340	C(~C)(~C)(~H)(~O)
0.1024	SUB21	>= 4 O
0.0013	SUB582	O=C-C-C-O
PF10613	Ligated ion channel L-glutamate- and glycine-binding site
0.3530	SUB364	C(~F)(~F)
0.0181	SUB25	>= 2 F
PF00984	UDP-glucose/GDP-mannose dehydrogenase family, central domain
0.3527	SUB32	>= 2 P
PF00884	Sulfatase
0.3514	SUB611	C-O-C-O-C
0.1486	SUB618	C-C-C-O-[#1]
0.1286	SUB861	CC1C(C)CCC1
0.0912	SUB243	>= 1 saturated or aromatic carbon-only ring size 9
0.0616	SUB145	>= 1 saturated or aromatic carbon-only ring size 5
0.0171	SUB736	Cc1cc(O)ccc1
PF03024	Folate receptor family
0.3511	SUB694	O=C-C-C-C-C-O
0.3251	SUB708	O=C-C-C-C-C(N)-C
0.2771	SUB379	C(~N)(:C)(:N)
0.1331	SUB495	O=C-C:N
0.0758	SUB695	O=C-C-C-C-C=O
0.0562	SUB717	Cc1ccc(N)cc1
PF06907	Latexin
0.3510	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.0113	SUB620	O-C-C=C-C
PF08040	MNLL subunit
0.3509	SUB158	>= 3 any ring size 5
0.1594	SUB32	>= 2 P
0.1366	SUB151	>= 2 any ring size 5
0.0846	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.0357	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF03953	Tubulin C-terminal domain
0.3490	SUB712	C-C(C)(C)-C-C
0.3294	SUB825	OC1C(O)CCCC1
0.2409	SUB465	N-C-C=C
0.1343	SUB757	Cc1c(O)cccc1
0.1284	SUB667	C=C-C-O-C
0.1054	SUB702	O-C-C-C-C-C(O)-C
0.0960	SUB595	C-O-C-C=C
0.0882	SUB433	C(-C)(-C)(=O)
0.0687	SUB218	>= 1 unsaturated non-aromatic carbon-only ring size 7
0.0532	SUB813	NC1CC(N)CCC1
0.0363	SUB463	O-C-C=O
0.0182	SUB547	N-C:C-[#1]
0.0079	SUB540	N=C-C-[#1]
0.0006	SUB538	O=C-C-O
0.0001	SUB582	O=C-C-C-O
PF01130	CD36 family
0.3488	SUB408	O(~C)(~P)
0.0447	SUB643	O-C-C-C=O
0.0399	SUB31	>= 1 P
0.0182	SUB582	O=C-C-C-O
PF04961	Formiminotransferase-cyclodeaminase
0.3486	SUB686	O=C-C-C-C-N
0.1188	SUB683	O-C-C-C-C-N
PF00696	Amino acid kinase family
0.3473	SUB694	O=C-C-C-C-C-O
0.2898	SUB695	O=C-C-C-C-C=O
PF00377	Prion/Doppel alpha-helical domain
0.3444	SUB560	O-C-N-[#1]
0.3402	SUB707	O=C-C-C-C-C(=O)-C
0.2599	SUB589	O=C-C-C=O
PF00749	tRNA synthetases class I (E and Q), , catalytic domain
0.3415	SUB694	O=C-C-C-C-C-O
0.2584	SUB695	O=C-C-C-C-C=O
0.0126	SUB339	C(~C)(~C)(~H)(~N)
PF00169	PH domain
0.3412	SUB407	O(~C)(~H)
0.2515	SUB3	>= 16 H
0.2464	SUB216	>= 1 saturated or aromatic nitrogen-containing ring size 7
0.2209	SUB682	O-C-C-C-C-O
0.1946	SUB214	>= 1 any ring size 7
0.1889	SUB217	>= 1 saturated or aromatic heteroatom-containing ring size 7
0.1159	SUB33	>= 4 P
0.0594	SUB408	O(~C)(~P)
0.0474	SUB453	C(-O)(=O)
0.0008	SUB2	>= 8 H
PF05676	NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7), 
0.3395	SUB158	>= 3 any ring size 5
0.1366	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0646	SUB360	C(~C)(:N)(:N)
0.0174	SUB261	>= 3 hetero-aromatic rings
0.0047	SUB389	C(:C)(:N)(:N)
PF02898	Nitric oxide synthase, oxygenase domain
0.3394	SUB340	C(~C)(~C)(~H)(~O)
0.3077	SUB16	>= 2 N
0.2772	SUB407	O(~C)(~H)
0.2498	SUB419	C=N
0.1760	SUB706	O=C-C-C-C-C(O)-C
0.0868	SUB338	C(~C)(~C)(~C)(~O)
PF00433	Protein kinase C terminal domain
0.3387	SUB756	Cc1c(C)cccc1
0.1177	SUB819	CC1C(C)CCCC1
0.0783	SUB294	C-S
0.0001	SUB354	C(~C)(~S)
PF08527	Protein-arginine deiminase (PAD),  middle domain
0.3384	SUB703	O-C-C-C-C-C-N-C
0.1110	SUB655	N-C-N-C-C
0.0997	SUB696	O=C-C-C-C-C-N
0.0234	SUB646	O=C-N-C-C
PF01546	Peptidase family M20/M25/M40
0.3379	SUB688	O=C-C-C-C=O
PF03917	Eukaryotic glutathione synthase, ATP binding domain
0.3363	SUB567	O-C-C-N
0.1322	SUB309	O-H
0.0228	SUB537	O=C-C-N
PF04952	Succinylglutamate desuccinylase / Aspartoacylase family
0.3359	SUB688	O=C-C-C-C=O
0.0897	SUB687	O=C-C-C-C-O
0.0757	SUB639	O-C-C-C-N
0.0746	SUB682	O-C-C-C-C-O
0.0617	SUB339	C(~C)(~C)(~H)(~N)
0.0278	SUB453	C(-O)(=O)
PF04051	Transport protein particle (TRAPP),  component
0.3353	SUB4	>= 32 H
PF02866	lactate/malate dehydrogenase, alpha/beta C-terminal domain
0.3333	SUB32	>= 2 P
0.2790	SUB440	C(-C)(-N)(=O)
0.1424	SUB407	O(~C)(~H)
0.0555	SUB446	C(-H)(-N)(=C)
0.0530	SUB389	C(:C)(:N)(:N)
0.0178	SUB444	C(-C)(=O)
0.0026	SUB673	O=C-C=C-[#1]
0.0003	SUB674	O=C-C=C-N
PF01712	Deoxynucleoside kinase
0.3317	SUB613	N-C-O-C-C
0.1647	SUB640	O-C-C-C-O
0.1441	SUB639	O-C-C-C-N
0.0727	SUB664	O-C-C-O-[#1]
0.0345	SUB556	N=C-C=C
PF00018	SH3 domain
0.3296	SUB626	O=C-C:C-O
0.3219	SUB261	>= 3 hetero-aromatic rings
0.2319	SUB407	O(~C)(~H)
0.2248	SUB339	C(~C)(~C)(~H)(~N)
0.2097	SUB309	O-H
0.1967	SUB715	Cc1ccc(O)cc1
0.1943	SUB608	N-C-C-C:C
0.1706	SUB568	O-C-C-O
0.0965	SUB193	>= 3 any ring size 6
0.0960	SUB262	>= 4 aromatic rings
0.0805	SUB426	P=O
0.0694	SUB315	O-P
0.0691	SUB412	P(~O)(~O)
0.0594	SUB714	Cc1ccc(C)cc1
0.0588	SUB457	P(-O)(=O)
0.0263	SUB517	[#1]-C=C-[#1]
0.0010	SUB31	>= 1 P
PF00246	Zinc carboxypeptidase
0.3285	SUB338	C(~C)(~C)(~C)(~O)
0.1323	SUB695	O=C-C-C-C-C=O
PF00136	DNA polymerase family B
0.3277	SUB389	C(:C)(:N)(:N)
0.0152	SUB24	>= 1 F
PF09166	Biliverdin reductase, catalytic
0.3277	SUB158	>= 3 any ring size 5
0.2897	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF00156	Phosphoribosyl transferase domain
0.3276	SUB379	C(~N)(:C)(:N)
0.2075	SUB360	C(~C)(:N)(:N)
0.1694	SUB242	>= 1 any ring size 9
0.1286	SUB341	C(~C)(~C)(~N)
0.0994	SUB500	N-C:C:N
0.0694	SUB548	N-C:C-N
0.0284	SUB529	[#1]-N-C-[#1]
0.0200	SUB486	N:C:C:N
0.0024	SUB389	C(:C)(:N)(:N)
PF08384	Pro-opiomelanocortin, N-terminal region
0.3266	SUB338	C(~C)(~C)(~C)(~O)
0.1445	SUB335	C(~C)(~C)(~C)(~C)
0.1334	SUB200	>= 4 any ring size 6
0.1156	SUB712	C-C(C)(C)-C-C
0.0209	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0197	SUB820	CC1C(O)CCCC1
0.0180	SUB620	O-C-C=C-C
0.0139	SUB574	O-C-C=C
PF00795	Carbon-nitrogen hydrolase
0.3264	SUB694	O=C-C-C-C-C-O
0.3242	SUB695	O=C-C-C-C-C=O
0.0044	SUB567	O-C-C-N
PF00890	FAD binding domain
0.3253	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.2655	SUB688	O=C-C-C-C=O
0.0315	SUB335	C(~C)(~C)(~C)(~C)
PF02727	Copper amine oxidase, N2 domain
0.3231	SUB394	N(~C)(~H)
0.0453	SUB511	[#1]-N-N-[#1]
PF00091	Tubulin/FtsZ family, GTPase domain
0.3228	SUB712	C-C(C)(C)-C-C
0.3127	SUB825	OC1C(O)CCCC1
0.2124	SUB465	N-C-C=C
0.1813	SUB757	Cc1c(O)cccc1
0.1258	SUB667	C=C-C-O-C
0.1092	SUB433	C(-C)(-C)(=O)
0.0998	SUB595	C-O-C-C=C
0.0645	SUB538	O=C-C-O
0.0563	SUB813	NC1CC(N)CCC1
0.0435	SUB463	O-C-C=O
0.0318	SUB582	O=C-C-C-O
0.0202	SUB547	N-C:C-[#1]
0.0083	SUB338	C(~C)(~C)(~C)(~O)
0.0044	SUB540	N=C-C-[#1]
0.0004	SUB643	O-C-C-C=O
PF01135	Protein-L-isoaspartate(D-aspartate),  O-methyltransferase (PCMT), 
0.3213	SUB413	S(~C)(~C)
0.0144	SUB537	O=C-C-N
PF09334	tRNA synthetases class I (M), 
0.3195	SUB350	C(~C)(~H)(~S)
0.2672	SUB413	S(~C)(~C)
0.0009	SUB369	C(~H)(~S)
PF05544	Proline racemase
0.3181	SUB696	O=C-C-C-C-C-N
0.0495	SUB146	>= 1 saturated or aromatic nitrogen-containing ring size 5
0.0088	SUB537	O=C-C-N
PF06212	GRIM-19 protein
0.3180	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1899	SUB158	>= 3 any ring size 5
PF00929	Exonuclease
0.3177	SUB315	O-P
0.2238	SUB407	O(~C)(~H)
0.0472	SUB426	P=O
0.0336	SUB31	>= 1 P
0.0263	SUB444	C(-C)(=O)
PF00112	Papain family cysteine protease
0.3166	SUB529	[#1]-N-C-[#1]
0.0739	SUB449	C(-H)(=O)
0.0507	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0441	SUB644	[#1]-C-C-N-[#1]
PF02127	Aminopeptidase I zinc metalloprotease (M18), 
0.3162	SUB695	O=C-C-C-C-C=O
0.2362	SUB694	O=C-C-C-C-C-O
PF01733	Nucleoside transporter
0.3152	SUB490	N-C-S-C
0.2649	SUB338	C(~C)(~C)(~C)(~O)
0.2176	SUB783	OC1CCC(O)CC1
0.0473	SUB720	Oc1ccc(O)cc1
PF02196	Raf-like Ras-binding domain
0.3133	SUB531	N:C-C:C
0.1136	SUB675	N-C-N-C:C
0.0684	SUB374	C(~H)(:N)
0.0479	SUB492	C-N:C-[#1]
0.0003	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
PF01179	Copper amine oxidase, enzyme domain
0.3132	SUB394	N(~C)(~H)
0.1308	SUB523	C-N-N-[#1]
0.0748	SUB511	[#1]-N-N-[#1]
PF00619	Caspase recruitment domain
0.3120	SUB414	S(~C)(~H)
0.0897	SUB683	O-C-C-C-C-N
0.0749	SUB32	>= 2 P
0.0252	SUB703	O-C-C-C-C-C-N-C
0.0001	SUB692	O-C-C-C-C-C-N
PF00704	Glycosyl hydrolases family 18
0.3097	SUB18	>= 8 N
0.2765	SUB572	[#1]-C-O-[#1]
0.0019	SUB683	O-C-C-C-C-N
PF03572	Peptidase family S41
0.3092	SUB183	>= 1 unsaturated non-aromatic carbon-only ring size 6
0.0034	SUB572	[#1]-C-O-[#1]
PF00999	Sodium/hydrogen exchanger family
0.3074	SUB537	O=C-C-N
0.1999	SUB603	O=C-C-N-C
0.0249	SUB657	C-C-N-C-C
PF00028	Cadherin domain
0.3072	SUB153	>= 2 saturated or aromatic nitrogen-containing ring size 5
0.1133	SUB625	O=C-C:C-N
0.0039	SUB686	O=C-C-C-C-N
PF00123	Peptide hormone
0.3072	SUB653	O-C:C:C-N
0.1892	SUB743	Oc1cc(N)ccc1
0.0964	SUB806	OC1CC(N)CCC1
PF04756	OST3 / OST6 family
0.3066	SUB756	Cc1c(C)cccc1
0.1091	SUB688	O=C-C-C-C=O
PF03372	Endonuclease/Exonuclease/phosphatase family
0.3062	SUB747	Sc1cc(N)ccc1
0.2029	SUB342	C(~C)(~C)(~O)
0.1757	SUB529	[#1]-N-C-[#1]
0.1715	SUB580	O=C-C-C-C
0.1270	SUB821	CC1C(S)CCCC1
0.1105	SUB630	S-C:C:C-N
0.0839	SUB810	SC1CC(N)CCC1
0.0614	SUB717	Cc1ccc(N)cc1
0.0398	SUB758	Cc1c(S)cccc1
0.0312	SUB582	O=C-C-C-O
0.0129	SUB408	O(~C)(~P)
0.0019	SUB643	O-C-C-C=O
PF00478	IMP dehydrogenase / GMP reductase domain
0.3056	SUB682	O-C-C-C-C-O
0.2328	SUB242	>= 1 any ring size 9
0.2323	SUB147	>= 1 saturated or aromatic heteroatom-containing ring size 5
0.1624	SUB390	C(:N)(:N)
0.1199	SUB256	>= 1 aromatic ring
0.1091	SUB654	O-C:C:C-O
0.1001	SUB573	N:C:N:C
0.0934	SUB374	C(~H)(:N)
0.0552	SUB741	Oc1cc(O)ccc1
0.0517	SUB691	O-C-C-C-C-C-O
0.0510	SUB494	O=C-C:C
0.0430	SUB505	N:C:N-C
0.0093	SUB492	C-N:C-[#1]
PF00111	2Fe-2S iron-sulfur cluster binding domain
0.3056	SUB674	O=C-C=C-N
0.1942	SUB361	C(~Cl)(~Cl)
0.1893	SUB556	N=C-C=C
0.1457	SUB673	O=C-C=C-[#1]
0.1380	SUB40	>= 4 Cl
0.1248	SUB431	C(-C)(-C)(=C)
0.0430	SUB344	C(~C)(~Cl)(~H)
0.0250	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0050	SUB158	>= 3 any ring size 5
PF04263	Thiamin pyrophosphokinase, catalytic domain
0.3053	SUB490	N-C-S-C
0.1404	SUB474	S-C:N:C
0.0543	SUB509	S=C-N-C
PF03949	Malic enzyme, NAD binding domain
0.3046	SUB158	>= 3 any ring size 5
0.1941	SUB21	>= 4 O
0.1915	SUB407	O(~C)(~H)
0.1232	SUB517	[#1]-C=C-[#1]
0.0754	SUB503	N-C=C-[#1]
0.0549	SUB664	O-C-C-O-[#1]
0.0487	SUB444	C(-C)(=O)
0.0358	SUB463	O-C-C=O
0.0191	SUB446	C(-H)(-N)(=C)
PF00033	Cytochrome b(N-terminal), /b6/petB
0.3017	SUB781	CC1CCC(Cl)CC1
PF00778	DIX domain
0.3011	SUB414	S(~C)(~H)
0.2023	SUB35	>= 2 S
PF00044	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
0.3005	SUB158	>= 3 any ring size 5
0.0561	SUB32	>= 2 P
PF03446	NAD binding domain of 6-phosphogluconate dehydrogenase
0.3002	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.2124	SUB158	>= 3 any ring size 5
PF00400	WD domain, G-beta repeat
0.2998	SUB572	[#1]-C-O-[#1]
0.0356	SUB613	N-C-O-C-C
PF01187	Macrophage migration inhibitory factor (MIF), 
0.2988	SUB691	O-C-C-C-C-C-O
0.2545	SUB582	O=C-C-C-O
0.0678	SUB643	O-C-C-C=O
PF09303	KCNMB2, ball and chain domain
0.2980	SUB648	O=C-N-C-N
PF00258	Flavodoxin
0.2977	SUB375	C(~H)(~H)(~H)
0.1556	SUB339	C(~C)(~C)(~H)(~N)
0.0755	SUB717	Cc1ccc(N)cc1
0.0075	SUB258	>= 2 aromatic rings
PF02274	Amidinotransferase
0.2973	SUB696	O=C-C-C-C-C-N
0.2003	SUB561	N-C-N-C
0.0741	SUB703	O-C-C-C-C-C-N-C
0.0390	SUB655	N-C-N-C-C
PF02743	Cache domain
0.2963	SUB683	O-C-C-C-C-N
0.0002	SUB697	C-C-C-C-C-C-C-C
PF00688	TGF-beta propeptide
0.2959	SUB190	>= 2 unsaturated non-aromatic carbon-only ring size 6
0.1390	SUB572	[#1]-C-O-[#1]
0.0295	SUB340	C(~C)(~C)(~H)(~O)
PF00560	Leucine Rich Repeat
0.2949	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.1350	SUB381	C(~O)(~O)
0.0778	SUB1	>= 4 H
0.0422	SUB407	O(~C)(~H)
0.0060	SUB702	O-C-C-C-C-C(O)-C
PF06617	M-phase inducer phosphatase
0.2945	SUB96	>= 1 Hg
0.2054	SUB284	C-H
0.1710	SUB369	C(~H)(~S)
0.0851	SUB350	C(~C)(~H)(~S)
PF01431	Peptidase family M13
0.2939	SUB647	O=C-N-C-[#1]
0.2296	SUB705	O=C-C-C-C-C-C-C
0.1780	SUB453	C(-O)(=O)
0.1436	SUB242	>= 1 any ring size 9
0.0470	SUB339	C(~C)(~C)(~H)(~N)
0.0278	SUB357	C(~C)(:C)(:C)
0.0138	SUB414	S(~C)(~H)
0.0119	SUB336	C(~C)(~C)(~C)(~H)
PF00051	Kringle domain
0.2924	SUB336	C(~C)(~C)(~C)(~H)
0.2546	SUB394	N(~C)(~H)
0.1903	SUB376	C(~N)(~N)
0.1771	SUB381	C(~O)(~O)
0.1441	SUB11	>= 4 C
0.1410	SUB419	C=N
0.1385	SUB529	[#1]-N-C-[#1]
0.1083	SUB454	N(-C)(=C)
0.0872	SUB644	[#1]-C-C-N-[#1]
0.0856	SUB438	C(-C)(-N)(=C)
0.0441	SUB386	C(:C)(:C)(:C)
0.0363	SUB249	>= 1 any ring size 10
0.0021	SUB421	C=O
PF01061	ABC-2 type transporter
0.2915	SUB801	CC1CC(N)CCC1
0.1544	SUB738	Cc1cc(N)ccc1
0.0465	SUB612	N-C-C-N-C
0.0169	SUB580	O=C-C-C-C
PF05790	Immunoglobulin C2-set domain
0.2907	SUB401	N(~H)(:C)(:C)
0.1242	SUB743	Oc1cc(N)ccc1
0.0984	SUB806	OC1CC(N)CCC1
0.0681	SUB653	O-C:C:C-N
0.0524	SUB664	O-C-C-O-[#1]
0.0056	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.0001	SUB528	C:C:N-[#1]
PF00614	Phospholipase D Active site motif
0.2906	SUB660	O-C-C-N-C
0.1777	SUB392	N(~C)(~C)(~C)
0.1484	SUB572	[#1]-C-O-[#1]
0.0156	SUB567	O-C-C-N
PF04072	Leucine carboxyl methyltransferase
0.2904	SUB567	O-C-C-N
0.2392	SUB336	C(~C)(~C)(~C)(~H)
0.0747	SUB339	C(~C)(~C)(~H)(~N)
PF01234	NNMT/PNMT/TEMT family
0.2899	SUB819	CC1C(C)CCCC1
0.2512	SUB756	Cc1c(C)cccc1
0.2377	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
0.2355	SUB629	C-N-C-C:C
0.1330	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.1012	SUB657	C-C-N-C-C
0.0632	SUB550	N-C-C:C
0.0079	SUB441	C(-C)(-O)(=O)
0.0037	SUB34	>= 1 S
0.0035	SUB524	N:C:C-C
0.0031	SUB294	C-S
0.0004	SUB354	C(~C)(~S)
PF01244	Membrane dipeptidase (Peptidase family M19), 
0.2896	SUB117	>= 1 saturated or aromatic carbon-only ring size 3
0.2104	SUB116	>= 1 any ring size 3
PF00373	FERM central domain
0.2896	SUB32	>= 2 P
0.0050	SUB804	OC1CC(O)CCC1
0.0013	SUB741	Oc1cc(O)ccc1
PF00185	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
0.2879	SUB537	O=C-C-N
0.1070	SUB529	[#1]-N-C-[#1]
0.0361	SUB441	C(-C)(-O)(=O)
0.0182	SUB567	O-C-C-N
PF01369	Sec7 domain
0.2876	SUB453	C(-O)(=O)
0.0838	SUB572	[#1]-C-O-[#1]
PF03765	CRAL/TRIO, N-terminus
0.2875	SUB4	>= 32 H
0.1854	SUB13	>= 16 C
0.1369	SUB697	C-C-C-C-C-C-C-C
0.0504	SUB698	C-C-C-C-C-C(C)-C
0.0171	SUB668	C=C-C-O-[#1]
0.0077	SUB633	C-C-O-C:C
PF01842	ACT domain
0.2873	SUB664	O-C-C-O-[#1]
0.1236	SUB700	O-C-C-C-C-C(C)-C
0.1075	SUB432	C(-C)(-C)(=N)
0.0961	SUB692	O-C-C-C-C-C-N
0.0115	SUB529	[#1]-N-C-[#1]
PF00499	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
0.2870	SUB158	>= 3 any ring size 5
0.1349	SUB446	C(-H)(-N)(=C)
0.0207	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF01118	Semialdehyde dehydrogenase, NAD binding domain
0.2857	SUB22	>= 8 O
0.0831	SUB4	>= 32 H
0.0359	SUB664	O-C-C-O-[#1]
PF01641	SelR domain
0.2853	SUB350	C(~C)(~H)(~S)
0.1468	SUB339	C(~C)(~C)(~H)(~N)
0.1358	SUB537	O=C-C-N
0.0458	SUB413	S(~C)(~C)
0.0355	SUB567	O-C-C-N
PF00147	Fibrinogen beta and gamma chains, C-terminal globular domain
0.2850	SUB348	C(~C)(~H)(~O)(~O)
0.1978	SUB23	>= 16 O
PF01058	NADH ubiquinone oxidoreductase, 20 Kd subunit
0.2830	SUB261	>= 3 hetero-aromatic rings
0.0244	SUB446	C(-H)(-N)(=C)
PF01590	GAF domain
0.2827	SUB21	>= 4 O
0.2460	SUB466	O=S-C-C
0.2082	SUB242	>= 1 any ring size 9
0.1971	SUB695	O=C-C-C-C-C=O
0.1184	SUB548	N-C:C-N
0.1122	SUB500	N-C:C:N
0.0274	SUB536	O=C-C-C
0.0244	SUB381	C(~O)(~O)
0.0003	SUB458	S(-C)(=O)
PF00208	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
0.2824	SUB683	O-C-C-C-C-N
0.2458	SUB695	O=C-C-C-C-C=O
0.1696	SUB360	C(~C)(:N)(:N)
0.0695	SUB691	O-C-C-C-C-C-O
PF00927	Transglutaminase family, C-terminal ig like domain
0.2820	SUB618	C-C-C-O-[#1]
0.2772	SUB440	C(-C)(-N)(=O)
0.1106	SUB692	O-C-C-C-C-C-N
0.0418	SUB495	O=C-C:N
0.0041	SUB615	C-C-O-C-C
PF00868	Transglutaminase family
0.2818	SUB440	C(-C)(-N)(=O)
0.1771	SUB618	C-C-C-O-[#1]
0.0228	SUB537	O=C-C-N
0.0025	SUB615	C-C-O-C-C
0.0001	SUB495	O=C-C:N
PF00206	Lyase
0.2814	SUB488	N-C=N-C
0.2067	SUB529	[#1]-N-C-[#1]
0.0423	SUB17	>= 4 N
PF02121	Phosphatidylinositol transfer protein
0.2813	SUB14	>= 32 C
0.2187	SUB804	OC1CC(O)CCC1
PF07347	NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a), 
0.2806	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1596	SUB158	>= 3 any ring size 5
PF01409	tRNA synthetases class II core domain (F), 
0.2792	SUB339	C(~C)(~C)(~H)(~N)
0.1804	SUB567	O-C-C-N
0.1113	SUB529	[#1]-N-C-[#1]
PF06079	Apyrase
0.2780	SUB309	O-H
0.2060	SUB407	O(~C)(~H)
0.0329	SUB640	O-C-C-C-O
0.0025	SUB1	>= 4 H
PF01262	Alanine dehydrogenase/PNT, C-terminal domain
0.2778	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.0951	SUB691	O-C-C-C-C-C-O
0.0551	SUB21	>= 4 O
0.0420	SUB683	O-C-C-C-C-N
0.0256	SUB580	O=C-C-C-C
PF00056	lactate/malate dehydrogenase, NAD binding domain
0.2757	SUB158	>= 3 any ring size 5
0.2395	SUB622	N-C:C:C:N
0.2389	SUB446	C(-H)(-N)(=C)
0.1949	SUB407	O(~C)(~H)
0.1937	SUB444	C(-C)(=O)
0.0897	SUB674	O=C-C=C-N
0.0559	SUB389	C(:C)(:N)(:N)
0.0260	SUB440	C(-C)(-N)(=O)
0.0020	SUB673	O=C-C=C-[#1]
0.0013	SUB32	>= 2 P
PF02008	CXXC zinc finger domain
0.2750	SUB394	N(~C)(~H)
0.0804	SUB452	C(-N)(=O)
PF04768	Protein of unknown function (DUF619), 
0.2746	SUB694	O=C-C-C-C-C-O
0.1514	SUB691	O-C-C-C-C-C-O
PF00561	alpha/beta hydrolase fold
0.2742	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0119	SUB621	C:C-O-C-C
0.0077	SUB633	C-C-O-C:C
PF00860	Permease family
0.2739	SUB662	O-C-O-C-C
0.2261	SUB564	O-C-O-C
PF10276	Zinc-finger domain
0.2739	SUB158	>= 3 any ring size 5
0.2096	SUB398	N(~C)(:C)(:C)
0.1653	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF01055	Glycosyl hydrolases family 31 
0.2732	SUB683	O-C-C-C-C-N
0.1755	SUB639	O-C-C-C-N
0.0838	SUB702	O-C-C-C-C-C(O)-C
0.0031	SUB196	>= 3 saturated or aromatic heteroatom-containing ring size 6
0.0021	SUB23	>= 16 O
PF03034	Phosphatidyl serine synthase
0.2727	SUB22	>= 8 O
0.2083	SUB537	O=C-C-N
0.0946	SUB582	O=C-C-C-O
0.0692	SUB643	O-C-C-C=O
PF00622	SPRY domain
0.2698	SUB433	C(-C)(-C)(=O)
0.0697	SUB440	C(-C)(-N)(=O)
0.0528	SUB704	O-C-C-C-C-C(N)-C
0.0062	SUB673	O=C-C=C-[#1]
PF00378	Enoyl-CoA hydratase/isomerase family
0.2697	SUB659	C-C-S-C-C
0.2550	SUB32	>= 2 P
0.1671	SUB22	>= 8 O
0.1217	SUB389	C(:C)(:N)(:N)
0.0915	SUB23	>= 16 O
0.0114	SUB261	>= 3 hetero-aromatic rings
PF03781	Formylglycine-generating sulfatase enzyme
0.2666	SUB375	C(~H)(~H)(~H)
0.2152	SUB640	O-C-C-C-O
0.0580	SUB572	[#1]-C-O-[#1]
PF03074	Glutamate-cysteine ligase
0.2661	SUB339	C(~C)(~C)(~H)(~N)
0.1811	SUB537	O=C-C-N
0.1240	SUB441	C(-C)(-O)(=O)
PF08127	Peptidase family C1 propeptide
0.2658	SUB698	C-C-C-C-C-C(C)-C
0.1919	SUB705	O=C-C-C-C-C-C-C
0.0844	SUB436	C(-C)(-H)(=N)
0.0773	SUB693	O=C-C-C-C-C-C
0.0481	SUB443	C(-C)(=N)
0.0061	SUB448	C(-H)(=N)
0.0007	SUB540	N=C-C-[#1]
PF00021	u-PAR/Ly-6 domain
0.2657	SUB662	O-C-O-C-C
0.2343	SUB564	O-C-O-C
PF03491	Serotonin (5-HT),  neurotransmitter transporter, N-terminus
0.2650	SUB3	>= 16 H
0.0463	SUB698	C-C-C-C-C-C(C)-C
PF00349	Hexokinase
0.2643	SUB682	O-C-C-C-C-O
0.1539	SUB691	O-C-C-C-C-C-O
0.1128	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0544	SUB663	O-C-C-O-C
PF10531	SLBB domain
0.2634	SUB389	C(:C)(:N)(:N)
0.1461	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0117	SUB158	>= 3 any ring size 5
PF02025	Interleukin 5
0.2614	SUB523	C-N-N-[#1]
0.1541	SUB516	N-N-C-C
0.0845	SUB399	N(~H)(~N)
PF02779	Transketolase, pyrimidine binding domain
0.2604	SUB22	>= 8 O
0.1617	SUB342	C(~C)(~C)(~O)
0.1016	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0529	SUB536	O=C-C-C
0.0002	SUB158	>= 3 any ring size 5
PF00088	Trefoil (P-type),  domain
0.2594	SUB639	O-C-C-C-N
0.0784	SUB702	O-C-C-C-C-C(O)-C
0.0055	SUB23	>= 16 O
0.0049	SUB683	O-C-C-C-C-N
PF00690	Cation transporter/ATPase, N-terminus
0.2568	SUB51	>= 1 Mg
0.1553	SUB39	>= 2 Cl
0.1547	SUB200	>= 4 any ring size 6
0.1539	SUB334	C(~C)(~C)(~C)
0.1437	SUB441	C(-C)(-O)(=O)
0.1057	SUB144	>= 1 any ring size 5
0.0800	SUB466	O=S-C-C
0.0609	SUB657	C-C-N-C-C
0.0577	SUB354	C(~C)(~S)
0.0448	SUB189	>= 2 saturated or aromatic heteroatom-containing ring size 6
0.0440	SUB375	C(~H)(~H)(~H)
0.0339	SUB597	N=C-N-C-C
0.0241	SUB66	>= 1 As
0.0228	SUB573	N:C:N:C
0.0224	SUB180	>= 1 saturated or aromatic carbon-only ring size 6
0.0201	SUB295	C-Cl
0.0089	SUB140	>= 2 saturated or aromatic heteroatom-containing ring size 4
0.0078	SUB505	N:C:N-C
0.0048	SUB38	>= 1 Cl
0.0014	SUB137	>= 2 any ring size 4
0.0010	SUB25	>= 2 F
0.0004	SUB336	C(~C)(~C)(~C)(~H)
0.0003	SUB390	C(:N)(:N)
PF02728	Copper amine oxidase, N3 domain
0.2554	SUB394	N(~C)(~H)
PF01363	FYVE zinc finger
0.2543	SUB32	>= 2 P
0.2457	SUB783	OC1CCC(O)CC1
PF00554	Rel homology domain (RHD), 
0.2538	SUB144	>= 1 any ring size 5
0.0823	SUB820	CC1C(O)CCCC1
PF00224	Pyruvate kinase, barrel domain
0.2533	SUB457	P(-O)(=O)
0.2380	SUB381	C(~O)(~O)
0.1897	SUB538	O=C-C-O
0.0843	SUB463	O-C-C=O
0.0654	SUB618	C-C-C-O-[#1]
0.0007	SUB342	C(~C)(~C)(~O)
PF02852	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
0.2529	SUB421	C=O
0.1113	SUB414	S(~C)(~H)
0.0974	SUB284	C-H
0.0869	SUB345	C(~C)(~H)
0.0036	SUB350	C(~C)(~H)(~S)
0.0030	SUB369	C(~H)(~S)
0.0015	SUB35	>= 2 S
PF07973	Threonyl and Alanyl tRNA synthetase second additional domain
0.2512	SUB441	C(-C)(-O)(=O)
0.2125	SUB537	O=C-C-N
0.0611	SUB529	[#1]-N-C-[#1]
0.0254	SUB339	C(~C)(~C)(~H)(~N)
0.0001	SUB644	[#1]-C-C-N-[#1]
PF09782	NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit
0.2503	SUB158	>= 3 any ring size 5
0.1628	SUB261	>= 3 hetero-aromatic rings
0.1515	SUB389	C(:C)(:N)(:N)
0.0401	SUB360	C(~C)(:N)(:N)
PF02770	Acyl-CoA dehydrogenase, middle domain
0.2495	SUB334	C(~C)(~C)(~C)
0.2395	SUB389	C(:C)(:N)(:N)
0.1379	SUB32	>= 2 P
0.1068	SUB261	>= 3 hetero-aromatic rings
0.1026	SUB664	O-C-C-O-[#1]
0.0902	SUB681	O-C-C-C-C-C
0.0800	SUB407	O(~C)(~H)
0.0610	SUB375	C(~H)(~H)(~H)
0.0378	SUB613	N-C-O-C-C
0.0131	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0068	SUB336	C(~C)(~C)(~C)(~H)
0.0016	SUB444	C(-C)(=O)
PF02161	Progesterone receptor
0.2476	SUB338	C(~C)(~C)(~C)(~O)
0.1797	SUB253	>= 1 unsaturated non-aromatic carbon-only ring size 10
0.1684	SUB840	CC1CC(C)CC1
0.0039	SUB249	>= 1 any ring size 10
0.0038	SUB798	CC1CC(C)CCC1
PF10637	Oxoglutarate and iron-dependent oxygenase degradation C-term
0.2472	SUB582	O=C-C-C-O
0.1287	SUB606	O=C-C-O-C
0.0647	SUB687	O=C-C-C-C-O
PF07732	Multicopper oxidase
0.2465	SUB96	>= 1 Hg
PF01747	ATP-sulfurylase
0.2461	SUB379	C(~N)(:C)(:N)
0.0877	SUB360	C(~C)(:N)(:N)
0.0752	SUB439	C(-C)(-N)(=N)
PF03623	Focal adhesion targeting region
0.2461	SUB691	O-C-C-C-C-C-O
0.1150	SUB258	>= 2 aromatic rings
0.1059	SUB654	O-C:C:C-O
0.0501	SUB804	OC1CC(O)CCC1
0.0354	SUB640	O-C-C-C-O
PF01035	6-O-methylguanine DNA methyltransferase, DNA binding domain
0.2460	SUB350	C(~C)(~H)(~S)
0.2443	SUB369	C(~H)(~S)
0.0973	SUB567	O-C-C-N
0.0152	SUB339	C(~C)(~C)(~H)(~N)
PF00383	Cytidine and deoxycytidylate deaminase zinc-binding region
0.2460	SUB664	O-C-C-O-[#1]
0.1754	SUB613	N-C-O-C-C
0.0500	SUB214	>= 1 any ring size 7
PF00390	Malic enzyme, N-terminal domain
0.2452	SUB158	>= 3 any ring size 5
0.2148	SUB444	C(-C)(=O)
0.0946	SUB640	O-C-C-C-O
0.0476	SUB517	[#1]-C=C-[#1]
0.0438	SUB664	O-C-C-O-[#1]
0.0232	SUB503	N-C=C-[#1]
0.0001	SUB21	>= 4 O
PF11555	EGFR receptor inhibitor Mig-6
0.2442	SUB151	>= 2 any ring size 5
0.0870	SUB531	N:C-C:C
0.0576	SUB612	N-C-C-N-C
PF02772	S-adenosylmethionine synthetase, central domain
0.2440	SUB587	C-S-C-C-C
0.1468	SUB537	O=C-C-N
0.0202	SUB441	C(-C)(-O)(=O)
PF00487	Fatty acid desaturase
0.2440	SUB600	[#1]-C-C=C-[#1]
0.0552	SUB13	>= 16 C
0.0449	SUB681	O-C-C-C-C-C
0.0434	SUB685	O=C-C-C-C-C
0.0064	SUB618	C-C-C-O-[#1]
PF01633	Choline/ethanolamine kinase
0.2440	SUB572	[#1]-C-O-[#1]
0.1936	SUB660	O-C-C-N-C
0.1388	SUB392	N(~C)(~C)(~C)
PF01243	Pyridoxamine 5"-phosphate oxidase
0.2433	SUB347	C(~C)(~H)(~O)
PF04716	ETC complex I subunit conserved region
0.2427	SUB408	O(~C)(~P)
0.0888	SUB261	>= 3 hetero-aromatic rings
0.0693	SUB158	>= 3 any ring size 5
0.0544	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0448	SUB389	C(:C)(:N)(:N)
PF00714	Interferon gamma
0.2426	SUB572	[#1]-C-O-[#1]
0.1525	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0816	SUB615	C-C-O-C-C
0.0728	SUB640	O-C-C-C-O
PF02971	Formiminotransferase domain
0.2424	SUB686	O=C-C-C-C-N
0.1461	SUB683	O-C-C-C-C-N
0.0386	SUB624	O=C-C:C-C
PF02737	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
0.2422	SUB360	C(~C)(:N)(:N)
0.1883	SUB389	C(:C)(:N)(:N)
0.1689	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.0687	SUB22	>= 8 O
PF00120	Glutamine synthetase, catalytic domain
0.2406	SUB695	O=C-C-C-C-C=O
PF00438	S-adenosylmethionine synthetase, N-terminal domain
0.2400	SUB537	O=C-C-N
0.2252	SUB587	C-S-C-C-C
PF02441	Flavoprotein
0.2389	SUB31	>= 1 P
0.1288	SUB457	P(-O)(=O)
0.1275	SUB412	P(~O)(~O)
0.1032	SUB426	P=O
0.0778	SUB408	O(~C)(~P)
0.0749	SUB315	O-P
PF05193	Peptidase M16 inactive domain
0.2385	SUB687	O=C-C-C-C-O
0.1241	SUB694	O=C-C-C-C-C-O
0.0682	SUB476	S-C=N-C
0.0517	SUB258	>= 2 aromatic rings
0.0514	SUB336	C(~C)(~C)(~C)(~H)
PF10417	C-terminal domain of 1-Cys peroxiredoxin
0.2378	SUB409	O(~H)(~S)
PF03308	ArgK protein
0.2375	SUB172	>= 5 any ring size 5
0.2304	SUB60	>= 1 Co
0.2100	SUB165	>= 4 any ring size 5
0.1918	SUB337	C(~C)(~C)(~C)(~N)
0.1456	SUB398	N(~C)(:C)(:C)
0.1347	SUB18	>= 8 N
PF00176	SNF2 family N-terminal domain
0.2357	SUB339	C(~C)(~C)(~H)(~N)
0.2193	SUB663	O-C-C-O-C
0.0959	SUB567	O-C-C-N
0.0508	SUB22	>= 8 O
PF00667	FAD binding domain
0.2357	SUB375	C(~H)(~H)(~H)
0.2170	SUB339	C(~C)(~C)(~H)(~N)
0.0795	SUB431	C(-C)(-C)(=C)
0.0098	SUB258	>= 2 aromatic rings
PF02769	AIR synthase related protein, C-terminal domain
0.2356	SUB695	O=C-C-C-C-C=O
0.1209	SUB537	O=C-C-N
PF00115	Cytochrome C and Quinol oxidase polypeptide I
0.2354	SUB637	C-N-C-N-C
0.0343	SUB647	O=C-N-C-[#1]
0.0343	SUB646	O=C-N-C-C
PF01471	Putative peptidoglycan binding domain
0.2354	SUB533	S-C:C-[#1]
0.1921	SUB440	C(-C)(-N)(=O)
0.1706	SUB492	C-N:C-[#1]
0.1459	SUB515	O-N-C-C
0.1150	SUB193	>= 3 any ring size 6
0.1124	SUB537	O=C-C-N
0.1098	SUB369	C(~H)(~S)
0.0881	SUB709	C-C(C)-C-C
0.0861	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0847	SUB336	C(~C)(~C)(~C)(~H)
0.0511	SUB700	O-C-C-C-C-C(C)-C
0.0358	SUB452	C(-N)(=O)
0.0320	SUB466	O=S-C-C
0.0300	SUB375	C(~H)(~H)(~H)
0.0041	SUB309	O-H
PF08702	Fibrinogen alpha/beta chain family
0.2338	SUB348	C(~C)(~H)(~O)(~O)
0.1168	SUB23	>= 16 O
PF00200	Disintegrin
0.2335	SUB348	C(~C)(~H)(~O)(~O)
PF01222	Ergosterol biosynthesis ERG4/ERG24 family
0.2329	SUB315	O-P
0.1809	SUB426	P=O
0.0039	SUB457	P(-O)(=O)
0.0002	SUB32	>= 2 P
PF01704	UTP--glucose-1-phosphate uridylyltransferase
0.2321	SUB32	>= 2 P
0.1414	SUB426	P=O
0.1122	SUB31	>= 1 P
0.1060	SUB457	P(-O)(=O)
0.0825	SUB408	O(~C)(~P)
0.0268	SUB412	P(~O)(~O)
0.0244	SUB315	O-P
0.0052	SUB23	>= 16 O
PF01259	SAICAR synthetase
0.2316	SUB682	O-C-C-C-C-O
0.0369	SUB688	O=C-C-C-C=O
PF00762	Ferrochelatase
0.2298	SUB441	C(-C)(-O)(=O)
0.2298	SUB702	O-C-C-C-C-C(O)-C
0.0017	SUB243	>= 1 saturated or aromatic carbon-only ring size 9
PF03520	KCNQ voltage-gated potassium channel
0.2275	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.1077	SUB258	>= 2 aromatic rings
PF04042	DNA polymerase alpha/epsilon subunit B
0.2273	SUB523	C-N-N-[#1]
0.0383	SUB301	N-N
0.0266	SUB439	C(-C)(-N)(=N)
PF02807	ATP:guanido phosphotransferase, N-terminal domain
0.2269	SUB489	N-C=N-[#1]
0.1330	SUB660	O-C-C-N-C
0.0638	SUB597	N=C-N-C-C
0.0631	SUB441	C(-C)(-O)(=O)
0.0044	SUB603	O=C-C-N-C
PF00586	AIR synthase related protein, N-terminal domain
0.2266	SUB529	[#1]-N-C-[#1]
0.1352	SUB537	O=C-C-N
0.0002	SUB695	O=C-C-C-C-C=O
PF02773	S-adenosylmethionine synthetase, C-terminal domain
0.2263	SUB587	C-S-C-C-C
0.0190	SUB453	C(-O)(=O)
PF00097	Zinc finger, C3HC4 type (RING finger), 
0.2253	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
PF01869	BadF/BadG/BcrA/BcrD ATPase family
0.2250	SUB348	C(~C)(~H)(~O)(~O)
0.1780	SUB368	C(~H)(~O)(~O)
0.0429	SUB704	O-C-C-C-C-C(N)-C
PF03099	Biotin/lipoate A/B protein ligase family
0.2250	SUB699	O-C-C-C-C-C-C-C
0.1959	SUB350	C(~C)(~H)(~S)
0.0809	SUB705	O=C-C-C-C-C-C-C
0.0154	SUB693	O=C-C-C-C-C-C
PF01619	Proline dehydrogenase
0.2245	SUB603	O=C-C-N-C
0.0866	SUB660	O-C-C-N-C
PF02574	Homocysteine S-methyltransferase
0.2230	SUB580	O=C-C-C-C
0.1976	SUB691	O-C-C-C-C-C-O
0.1795	SUB339	C(~C)(~C)(~H)(~N)
0.1332	SUB413	S(~C)(~C)
0.1198	SUB587	C-S-C-C-C
0.0899	SUB638	O-C-C-C-C
0.0640	SUB618	C-C-C-O-[#1]
0.0122	SUB567	O-C-C-N
PF01841	Transglutaminase-like superfamily
0.2229	SUB440	C(-C)(-N)(=O)
0.1937	SUB537	O=C-C-N
0.1429	SUB618	C-C-C-O-[#1]
0.0085	SUB615	C-C-O-C-C
0.0001	SUB495	O=C-C:N
PF03508	Gap junction alpha-1 protein (Cx43), 
0.2220	SUB653	O-C:C:C-N
0.1027	SUB743	Oc1cc(N)ccc1
0.0488	SUB806	OC1CC(N)CCC1
PF00574	Clp protease
0.2214	SUB367	C(~H)(~O)
0.1496	SUB20	>= 2 O
0.1290	SUB449	C(-H)(=O)
PF00029	Connexin
0.2210	SUB806	OC1CC(N)CCC1
0.1462	SUB653	O-C:C:C-N
0.0949	SUB743	Oc1cc(N)ccc1
PF06888	Putative Phosphatase
0.2202	SUB572	[#1]-C-O-[#1]
0.0434	SUB660	O-C-C-N-C
0.0346	SUB392	N(~C)(~C)(~C)
PF00918	Gastrin/cholecystokinin family
0.2196	SUB631	O-C:C-O-C
0.2141	SUB545	O-C:C-O
0.2022	SUB762	Oc1c(O)cccc1
0.1964	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
0.1582	SUB228	>= 1 any ring size 8
0.0608	SUB632	O-C:C-O-[#1]
PF10397	Adenylosuccinate lyase C-terminus
0.2195	SUB489	N-C=N-[#1]
PF03160	Calx-beta domain
0.2187	SUB375	C(~H)(~H)(~H)
0.0646	SUB10	>= 2 C
PF00675	Insulinase (Peptidase family M16), 
0.2175	SUB694	O=C-C-C-C-C-O
0.1873	SUB687	O=C-C-C-C-O
0.0843	SUB23	>= 16 O
0.0657	SUB258	>= 2 aromatic rings
0.0277	SUB336	C(~C)(~C)(~C)(~H)
PF10590	Pyridoxine 5"-phosphate oxidase C-terminal dimerisation region
0.2174	SUB347	C(~C)(~H)(~O)
0.1860	SUB315	O-P
0.0393	SUB414	S(~C)(~H)
PF09127	Leukotriene A4 hydrolase, C-terminal
0.2166	SUB285	C-C
0.1448	SUB345	C(~C)(~H)
0.1160	SUB284	C-H
0.1144	SUB441	C(-C)(-O)(=O)
0.0131	SUB393	N(~C)(~C)(~H)
PF00725	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
0.2162	SUB360	C(~C)(:N)(:N)
0.1151	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.0920	SUB22	>= 8 O
0.0891	SUB389	C(:C)(:N)(:N)
PF00357	Integrin alpha cytoplasmic region
0.2152	SUB647	O=C-N-C-[#1]
0.2124	SUB200	>= 4 any ring size 6
0.2000	SUB4	>= 32 H
0.0734	SUB446	C(-H)(-N)(=C)
PF01562	Reprolysin family propeptide
0.2141	SUB348	C(~C)(~H)(~O)(~O)
PF06021	Aralkyl acyl-CoA:amino acid N-acyltransferase
0.2128	SUB441	C(-C)(-O)(=O)
0.1223	SUB567	O-C-C-N
0.0507	SUB529	[#1]-N-C-[#1]
PF08122	NADH-ubiquinone oxidoreductase B12 subunit family
0.2128	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1919	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0953	SUB398	N(~C)(:C)(:C)
PF02493	MORN repeat
0.2125	SUB389	C(:C)(:N)(:N)
0.0964	SUB398	N(~C)(:C)(:C)
PF10582	Gap junction channel protein cysteine-rich domain
0.2123	SUB806	OC1CC(N)CCC1
0.0774	SUB743	Oc1cc(N)ccc1
0.0413	SUB653	O-C:C:C-N
PF05649	Peptidase family M13
0.2122	SUB647	O=C-N-C-[#1]
0.1990	SUB242	>= 1 any ring size 9
0.1286	SUB414	S(~C)(~H)
0.0796	SUB339	C(~C)(~C)(~H)(~N)
0.0074	SUB336	C(~C)(~C)(~C)(~H)
PF00274	Fructose-bisphosphate aldolase class-I
0.2119	SUB687	O=C-C-C-C-O
0.2119	SUB694	O=C-C-C-C-C-O
0.0424	SUB538	O=C-C-O
PF00899	ThiF family
0.2118	SUB389	C(:C)(:N)(:N)
0.1062	SUB505	N:C:N-C
0.0950	SUB573	N:C:N:C
PF00931	NB-ARC domain
0.2109	SUB572	[#1]-C-O-[#1]
0.0137	SUB439	C(-C)(-N)(=N)
PF02812	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
0.2099	SUB683	O-C-C-C-C-N
0.1581	SUB389	C(:C)(:N)(:N)
0.0553	SUB691	O-C-C-C-C-C-O
PF02771	Acyl-CoA dehydrogenase, N-terminal domain
0.2088	SUB334	C(~C)(~C)(~C)
0.1278	SUB664	O-C-C-O-[#1]
0.1192	SUB32	>= 2 P
0.1118	SUB261	>= 3 hetero-aromatic rings
0.0922	SUB375	C(~H)(~H)(~H)
0.0868	SUB681	O-C-C-C-C-C
0.0578	SUB444	C(-C)(=O)
0.0472	SUB387	C(:C)(:C)(:N)
0.0448	SUB407	O(~C)(~H)
0.0130	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0001	SUB613	N-C-O-C-C
PF02837	Glycosyl hydrolases family 2, sugar binding domain
0.2088	SUB348	C(~C)(~H)(~O)(~O)
PF02173	pKID domain
0.2083	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.0043	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0001	SUB181	>= 1 saturated or aromatic nitrogen-containing ring size 6
PF01149	Formamidopyrimidine-DNA glycosylase N-terminal domain
0.2080	SUB337	C(~C)(~C)(~C)(~N)
PF02785	Biotin carboxylase C-terminal domain
0.2077	SUB441	C(-C)(-O)(=O)
0.0461	SUB453	C(-O)(=O)
0.0003	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
PF00340	Interleukin-1 / 18
0.2074	SUB738	Cc1cc(N)ccc1
0.1435	SUB801	CC1CC(N)CCC1
PF00521	DNA gyrase/topoisomerase IV, subunit A
0.2067	SUB249	>= 1 any ring size 10
0.1202	SUB444	C(-C)(=O)
0.1108	SUB186	>= 2 any ring size 6
0.0944	SUB644	[#1]-C-C-N-[#1]
0.0922	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.0101	SUB393	N(~C)(~C)(~H)
0.0081	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
PF00019	Transforming growth factor beta like domain
0.2058	SUB572	[#1]-C-O-[#1]
0.0351	SUB340	C(~C)(~C)(~H)(~O)
PF07479	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
0.2057	SUB613	N-C-O-C-C
0.0979	SUB261	>= 3 hetero-aromatic rings
PF05199	GMC oxidoreductase
0.2052	SUB660	O-C-C-N-C
0.0132	SUB572	[#1]-C-O-[#1]
PF00152	tRNA synthetases class II (D, K and N),  
0.2047	SUB339	C(~C)(~C)(~H)(~N)
0.0460	SUB16	>= 2 N
0.0183	SUB567	O-C-C-N
0.0143	SUB644	[#1]-C-C-N-[#1]
PF01477	PLAT/LH2 domain
0.2035	SUB646	O=C-N-C-C
0.1954	SUB549	O-C-C:C
0.1952	SUB699	O-C-C-C-C-C-C-C
0.1885	SUB375	C(~H)(~H)(~H)
0.1441	SUB260	>= 3 aromatic rings
0.1399	SUB12	>= 8 C
0.0991	SUB694	O=C-C-C-C-C-O
0.0524	SUB338	C(~C)(~C)(~C)(~O)
0.0267	SUB599	Cl-C:C:C-C
0.0182	SUB647	O=C-N-C-[#1]
0.0103	SUB499	O-C=C-C
0.0059	SUB504	Cl-C:C-[#1]
0.0025	SUB502	Cl-C:C-C
0.0001	SUB363	C(~Cl)(:C)
PF00535	Glycosyl transferase family 2
0.2034	SUB683	O-C-C-C-C-N
0.0639	SUB664	O-C-C-O-[#1]
0.0448	SUB639	O-C-C-C-N
PF00418	Tau and MAP protein, tubulin-binding repeat
0.2021	SUB362	C(~Cl)(~H)
0.1498	SUB862	CC1C(O)CCC1
0.1082	SUB344	C(~C)(~Cl)(~H)
0.0242	SUB610	Cl-C-C-N-C
0.0020	SUB841	CC1CC(O)CC1
PF00756	Putative esterase
0.2019	SUB369	C(~H)(~S)
0.1935	SUB696	O=C-C-C-C-C-N
0.0928	SUB695	O=C-C-C-C-C=O
0.0118	SUB350	C(~C)(~H)(~S)
PF02201	SWIB/MDM2 domain
0.2016	SUB676	Br-C-C-C:C
0.1311	SUB671	Br-C:C:C-C
0.1257	SUB331	C(~Br)(:C)
0.1218	SUB44	>= 1 Br
0.0775	SUB555	Br-C-C-C
0.0614	SUB45	>= 2 Br
PF00578	AhpC/TSA family
0.2014	SUB409	O(~H)(~S)
PF00650	CRAL/TRIO domain
0.2006	SUB621	C:C-O-C-C
0.1810	SUB4	>= 32 H
0.0943	SUB633	C-C-O-C:C
0.0759	SUB13	>= 16 C
0.0586	SUB697	C-C-C-C-C-C-C-C
0.0208	SUB668	C=C-C-O-[#1]
0.0034	SUB698	C-C-C-C-C-C(C)-C
PF02886	LBP / BPI / CETP family, C-terminal domain
0.2004	SUB14	>= 32 C
0.0760	SUB457	P(-O)(=O)
0.0287	SUB426	P=O
PF01699	Sodium/calcium exchanger protein
0.1981	SUB441	C(-C)(-O)(=O)
0.1238	SUB453	C(-O)(=O)
PF07837	Formiminotransferase domain, N-terminal subdomain
0.1972	SUB686	O=C-C-C-C-N
0.0460	SUB683	O-C-C-C-C-N
PF12062	heparan sulfate-N-deacetylase
0.1971	SUB261	>= 3 hetero-aromatic rings
0.1130	SUB389	C(:C)(:N)(:N)
0.0991	SUB602	N-C:C:C-N
0.0590	SUB622	N-C:C:C:N
0.0318	SUB360	C(~C)(:N)(:N)
PF01151	GNS1/SUR4 family
0.1953	SUB441	C(-C)(-O)(=O)
0.0097	SUB690	O-C-C-C-C-C-C
0.0043	SUB699	O-C-C-C-C-C-C-C
PF07648	Kazal-type serine protease inhibitor domain
0.1951	SUB441	C(-C)(-O)(=O)
0.1504	SUB453	C(-O)(=O)
0.0333	SUB620	O-C-C=C-C
PF00507	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
0.1950	SUB486	N:C:C:N
0.1950	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1020	SUB602	N-C:C:C-N
0.0468	SUB389	C(:C)(:N)(:N)
0.0462	SUB261	>= 3 hetero-aromatic rings
PF00731	AIR carboxylase
0.1947	SUB688	O=C-C-C-C=O
PF00221	Phenylalanine and histidine ammonia-lyase
0.1936	SUB500	N-C:C:N
0.1515	SUB486	N:C:C:N
0.0863	SUB489	N-C=N-[#1]
0.0687	SUB548	N-C:C-N
PF01336	OB-fold nucleic acid binding domain
0.1924	SUB581	O=C-C-C-N
0.1916	SUB687	O=C-C-C-C-O
0.1345	SUB339	C(~C)(~C)(~H)(~N)
0.0363	SUB567	O-C-C-N
0.0118	SUB644	[#1]-C-C-N-[#1]
0.0063	SUB16	>= 2 N
PF03662	Glycosyl hydrolase family 79, N-terminal domain 
0.1891	SUB36	>= 4 S
0.1725	SUB409	O(~H)(~S)
0.1384	SUB203	>= 4 saturated or aromatic heteroatom-containing ring size 6
PF04116	Fatty acid hydroxylase superfamily
0.1888	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1654	SUB158	>= 3 any ring size 5
0.0937	SUB389	C(:C)(:N)(:N)
PF02205	WH2 motif
0.1851	SUB510	Br-C:C-C
PF08377	MAP2/Tau projection domain
0.1834	SUB841	CC1CC(O)CC1
0.1268	SUB344	C(~C)(~Cl)(~H)
0.0967	SUB862	CC1C(O)CCC1
0.0809	SUB362	C(~Cl)(~H)
0.0713	SUB610	Cl-C-C-N-C
PF08429	PLU-1-like protein
0.1819	SUB606	O=C-C-O-C
PF02749	Quinolinate phosphoribosyl transferase, N-terminal domain
0.1816	SUB625	O=C-C:C-N
0.0721	SUB577	N=C-C:C-[#1]
0.0440	SUB540	N=C-C-[#1]
PF00173	Cytochrome b5-like Heme/Steroid binding domain
0.1779	SUB375	C(~H)(~H)(~H)
0.1404	SUB552	Cl-C-C-O
0.1199	SUB364	C(~F)(~F)
0.1188	SUB13	>= 16 C
0.0542	SUB344	C(~C)(~Cl)(~H)
0.0247	SUB705	O=C-C-C-C-C-C-C
0.0077	SUB362	C(~Cl)(~H)
PF08035	Opioids neuropeptide
0.1723	SUB712	C-C(C)(C)-C-C
0.1166	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0410	SUB338	C(~C)(~C)(~C)(~O)
0.0403	SUB620	O-C-C=C-C
0.0209	SUB574	O-C-C=C
PF01404	Ephrin receptor ligand binding domain
0.1709	SUB378	C(~N)(:C)(:C)
0.0916	SUB509	S=C-N-C
0.0034	SUB3	>= 16 H
0.0006	SUB835	NC1C(Cl)CCCC1
0.0003	SUB512	S=C-N-[#1]
0.0002	SUB759	Cc1c(N)cccc1
PF02188	GoLoco motif
0.1705	SUB338	C(~C)(~C)(~C)(~O)
PF02970	Tubulin binding cofactor A
0.1703	SUB441	C(-C)(-O)(=O)
0.0590	SUB453	C(-O)(=O)
PF04679	ATP dependent DNA ligase C terminal region        
0.1689	SUB560	O-C-N-[#1]
0.1002	SUB509	S=C-N-C
0.0900	SUB490	N-C-S-C
0.0839	SUB489	N-C=N-[#1]
0.0666	SUB476	S-C=N-C
0.0637	SUB160	>= 3 saturated or aromatic nitrogen-containing ring size 5
0.0253	SUB474	S-C:N:C
0.0001	SUB462	O-C-C=N
PF00441	Acyl-CoA dehydrogenase, C-terminal domain
0.1651	SUB375	C(~H)(~H)(~H)
0.1501	SUB334	C(~C)(~C)(~C)
0.1441	SUB664	O-C-C-O-[#1]
0.1364	SUB32	>= 2 P
0.0989	SUB261	>= 3 hetero-aromatic rings
0.0837	SUB681	O-C-C-C-C-C
0.0194	SUB444	C(-C)(=O)
0.0097	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
PF01212	Beta-eliminating lyase
0.1647	SUB567	O-C-C-N
0.0792	SUB462	O-C-C=N
0.0135	SUB407	O(~C)(~H)
0.0009	SUB421	C=O
0.0004	SUB444	C(-C)(=O)
PF08996	DNA Polymerase alpha zinc finger
0.1647	SUB24	>= 1 F
0.0936	SUB261	>= 3 hetero-aromatic rings
0.0743	SUB288	C-F
PF00571	CBS domain
0.1639	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.1547	SUB624	O=C-C:C-C
0.1382	SUB439	C(-C)(-N)(=N)
0.1154	SUB441	C(-C)(-O)(=O)
0.0976	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
0.0738	SUB576	O-C-C:C-O
0.0716	SUB615	C-C-O-C-C
0.0628	SUB703	O-C-C-C-C-C-N-C
0.0582	SUB618	C-C-C-O-[#1]
0.0538	SUB444	C(-C)(=O)
0.0486	SUB687	O=C-C-C-C-O
0.0477	SUB492	C-N:C-[#1]
0.0417	SUB700	O-C-C-C-C-C(C)-C
0.0349	SUB713	C-C(C)-C(C)-C
PF00236	Glycoprotein hormone
0.1631	SUB368	C(~H)(~O)(~O)
0.0697	SUB348	C(~C)(~H)(~O)(~O)
0.0675	SUB702	O-C-C-C-C-C(O)-C
0.0384	SUB572	[#1]-C-O-[#1]
PF07687	Peptidase dimerisation domain
0.1621	SUB688	O=C-C-C-C=O
PF08669	Glycine cleavage T-protein C-terminal barrel domain
0.1609	SUB674	O=C-C=C-N
0.1466	SUB691	O-C-C-C-C-C-O
0.0874	SUB717	Cc1ccc(N)cc1
0.0856	SUB673	O=C-C=C-[#1]
0.0852	SUB378	C(~N)(:C)(:C)
0.0674	SUB708	O=C-C-C-C-C(N)-C
0.0253	SUB780	CC1CCC(N)CC1
0.0191	SUB594	N-C-C-C-N
0.0151	SUB683	O-C-C-C-C-N
PF01266	FAD dependent oxidoreductase
0.1599	SUB537	O=C-C-N
0.1009	SUB453	C(-O)(=O)
PF01268	Formate--tetrahydrofolate ligase
0.1590	SUB441	C(-C)(-O)(=O)
0.1348	SUB407	O(~C)(~H)
PF02145	Rap/ran-GAP
0.1584	SUB338	C(~C)(~C)(~C)(~O)
PF00581	Rhodanese-like domain
0.1581	SUB369	C(~H)(~S)
0.0699	SUB350	C(~C)(~H)(~S)
0.0001	SUB284	C-H
PF03404	Mo-co oxidoreductase dimerisation domain
0.1574	SUB158	>= 3 any ring size 5
0.0201	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF01042	Endoribonuclease L-PSP
0.1568	SUB673	O=C-C=C-[#1]
0.1544	SUB668	C=C-C-O-[#1]
0.0144	SUB441	C(-C)(-O)(=O)
PF10391	Fingers domain of DNA polymerase lambda
0.1561	SUB439	C(-C)(-N)(=N)
0.1561	SUB613	N-C-O-C-C
0.1561	SUB655	N-C-N-C-C
PF07965	Integrin beta tail domain
0.1555	SUB4	>= 32 H
0.1211	SUB700	O-C-C-C-C-C(C)-C
0.0187	SUB369	C(~H)(~S)
0.0087	SUB705	O=C-C-C-C-C-C-C
0.0003	SUB642	O-C-C-C=C
0.0001	SUB350	C(~C)(~H)(~S)
PF02729	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
0.1549	SUB537	O=C-C-N
0.0916	SUB441	C(-C)(-O)(=O)
0.0541	SUB529	[#1]-N-C-[#1]
0.0262	SUB567	O-C-C-N
PF01231	Indoleamine 2,3-dioxygenase
0.1538	SUB759	Cc1c(N)cccc1
0.1039	SUB700	O-C-C-C-C-C(C)-C
0.0439	SUB401	N(~H)(:C)(:C)
0.0409	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
PF01408	Oxidoreductase family, NAD-binding Rossmann fold
0.1530	SUB158	>= 3 any ring size 5
0.0919	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.0054	SUB446	C(-H)(-N)(=C)
PF01327	Polypeptide deformylase
0.1529	SUB515	O-N-C-C
0.1310	SUB603	O=C-C-N-C
0.0939	SUB396	N(~C)(~O)
0.0825	SUB302	N-O
PF01833	IPT/TIG domain
0.1526	SUB168	>= 4 saturated or aromatic heteroatom-containing ring size 5
0.0971	SUB263	>= 4 hetero-aromatic rings
0.0721	SUB801	CC1CC(N)CCC1
0.0721	SUB771	Nc1c(N)cccc1
0.0272	SUB717	Cc1ccc(N)cc1
0.0083	SUB708	O=C-C-C-C-C(N)-C
PF01257	Respiratory-chain NADH dehydrogenase 24 Kd subunit
0.1503	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1391	SUB32	>= 2 P
0.0907	SUB622	N-C:C:C:N
0.0795	SUB158	>= 3 any ring size 5
PF00474	Sodium:solute symporter family
0.1498	SUB147	>= 1 saturated or aromatic heteroatom-containing ring size 5
0.1496	SUB350	C(~C)(~H)(~S)
0.0869	SUB309	O-H
0.0836	SUB407	O(~C)(~H)
0.0771	SUB705	O=C-C-C-C-C-C-C
0.0745	SUB2	>= 8 H
0.0440	SUB541	C-N-C-[#1]
PF00317	Ribonucleotide reductase, all-alpha domain
0.1489	SUB376	C(~N)(~N)
0.0412	SUB24	>= 1 F
PF00536	SAM domain (Sterile alpha motif), 
0.1485	SUB378	C(~N)(:C)(:C)
0.0037	SUB3	>= 16 H
0.0037	SUB581	O=C-C-C-N
0.0008	SUB534	S-C:C-N
0.0006	SUB474	S-C:N:C
0.0001	SUB625	O=C-C:C-N
PF00032	Cytochrome b(C-terminal), /b6/petD
0.1482	SUB718	Cc1ccc(Cl)cc1
0.0501	SUB781	CC1CCC(Cl)CC1
PF01068	ATP dependent DNA ligase domain
0.1477	SUB489	N-C=N-[#1]
0.0560	SUB490	N-C-S-C
0.0516	SUB462	O-C-C=N
0.0308	SUB476	S-C=N-C
0.0293	SUB509	S=C-N-C
0.0183	SUB560	O-C-N-[#1]
0.0034	SUB196	>= 3 saturated or aromatic heteroatom-containing ring size 6
PF00703	domain
0.1464	SUB348	C(~C)(~H)(~O)(~O)
PF02146	Sir2 family
0.1457	SUB809	SC1CC(S)CCC1
0.1351	SUB726	Sc1ccc(N)cc1
0.0989	SUB821	CC1C(S)CCCC1
0.0527	SUB789	SC1CCC(N)CC1
0.0397	SUB630	S-C:C:C-N
0.0268	SUB746	Sc1cc(S)ccc1
0.0008	SUB409	O(~H)(~S)
0.0003	SUB758	Cc1c(S)cccc1
PF07831	Pyrimidine nucleoside phosphorylase C-terminal domain
0.1443	SUB562	Cl-C-C=O
0.0487	SUB633	C-C-O-C:C
PF09326	Domain of unknown function (DUF1982), 
0.1436	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF06373	Cocaine and amphetamine regulated transcript protein (CART), 
0.1435	SUB339	C(~C)(~C)(~H)(~N)
PF00108	Thiolase, N-terminal domain
0.1422	SUB294	C-S
0.1421	SUB354	C(~C)(~S)
0.1145	SUB531	N:C-C:C
0.1062	SUB485	N-C:N:C
0.0946	SUB675	N-C-N-C:C
PF02347	Glycine cleavage system P-protein
0.1412	SUB407	O(~C)(~H)
0.0983	SUB567	O-C-C-N
0.0011	SUB421	C=O
0.0008	SUB444	C(-C)(=O)
0.0001	SUB588	N-C:C-O-[#1]
PF08526	Protein-arginine deiminase (PAD),  N-terminal domain
0.1396	SUB703	O-C-C-C-C-C-N-C
0.0698	SUB655	N-C-N-C-C
0.0694	SUB696	O=C-C-C-C-C-N
0.0638	SUB646	O=C-N-C-C
PF00976	Corticotropin ACTH domain
0.1370	SUB335	C(~C)(~C)(~C)(~C)
0.0499	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
0.0239	SUB820	CC1C(O)CCCC1
0.0237	SUB620	O-C-C=C-C
0.0201	SUB200	>= 4 any ring size 6
0.0146	SUB574	O-C-C=C
PF00362	Integrin, beta chain
0.1358	SUB369	C(~H)(~S)
0.0913	SUB4	>= 32 H
0.0883	SUB190	>= 2 unsaturated non-aromatic carbon-only ring size 6
0.0462	SUB705	O=C-C-C-C-C-C-C
0.0325	SUB642	O-C-C-C=C
0.0033	SUB350	C(~C)(~H)(~S)
PF00204	DNA gyrase B
0.1342	SUB249	>= 1 any ring size 10
0.1234	SUB186	>= 2 any ring size 6
0.0826	SUB644	[#1]-C-C-N-[#1]
0.0664	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
0.0211	SUB187	>= 2 saturated or aromatic carbon-only ring size 6
PF02803	Thiolase, C-terminal domain
0.1334	SUB531	N:C-C:C
0.1146	SUB354	C(~C)(~S)
0.0948	SUB294	C-S
0.0769	SUB379	C(~N)(:C)(:N)
PF02910	domain
0.1333	SUB688	O=C-C-C-C=O
0.0259	SUB682	O-C-C-C-C-O
PF03068	Protein-arginine deiminase (PAD), 
0.1333	SUB703	O-C-C-C-C-C-N-C
0.1035	SUB646	O=C-N-C-C
0.0724	SUB696	O=C-C-C-C-C-N
PF09292	Endonuclease VIII-like 1, DNA bind
0.1293	SUB337	C(~C)(~C)(~C)(~N)
0.0023	SUB640	O-C-C-C-O
PF01279	Parathyroid hormone family
0.1288	SUB690	O-C-C-C-C-C-C
0.0617	SUB618	C-C-C-O-[#1]
0.0183	SUB537	O=C-C-N
0.0022	SUB693	O=C-C-C-C-C-C
PF02872	5"-nucleotidase, C-terminal domain
0.1281	SUB244	>= 1 saturated or aromatic nitrogen-containing ring size 9
0.0070	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
PF02780	Transketolase, C-terminal domain
0.1281	SUB536	O=C-C-C
0.1114	SUB342	C(~C)(~C)(~O)
PF05222	Alanine dehydrogenase/PNT, N-terminal domain
0.1278	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
0.1194	SUB21	>= 4 O
0.1103	SUB245	>= 1 saturated or aromatic heteroatom-containing ring size 9
0.0998	SUB691	O-C-C-C-C-C-O
0.0826	SUB683	O-C-C-C-C-N
0.0153	SUB580	O=C-C-C-C
PF02870	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
0.1274	SUB537	O=C-C-N
0.0832	SUB567	O-C-C-N
0.0058	SUB369	C(~H)(~S)
PF04775	Acyl-CoA thioester hydrolase/BAAT N-terminal region
0.1268	SUB537	O=C-C-N
0.1268	SUB529	[#1]-N-C-[#1]
PF01569	PAP2 superfamily
0.1263	SUB572	[#1]-C-O-[#1]
0.0718	SUB660	O-C-C-N-C
0.0438	SUB392	N(~C)(~C)(~C)
PF01064	Activin types I and II receptor domain
0.1247	SUB32	>= 2 P
PF03199	Eukaryotic glutathione synthase
0.1217	SUB567	O-C-C-N
0.0923	SUB309	O-H
0.0139	SUB537	O=C-C-N
PF03727	Hexokinase
0.1207	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0975	SUB663	O-C-C-O-C
PF00129	Class I Histocompatibility antigen, domains alpha 1 and 2
0.1196	SUB662	O-C-O-C-C
0.0003	SUB564	O-C-O-C
PF00856	SET domain
0.1161	SUB398	N(~C)(:C)(:C)
0.0191	SUB587	C-S-C-C-C
0.0191	SUB537	O=C-C-N
PF08742	C8 domain
0.1152	SUB653	O-C:C:C-N
0.0791	SUB462	O-C-C=N
0.0790	SUB704	O-C-C-C-C-C(N)-C
0.0126	SUB743	Oc1cc(N)ccc1
PF02867	Ribonucleotide reductase, barrel domain
0.1149	SUB396	N(~C)(~O)
0.1063	SUB24	>= 1 F
0.0813	SUB376	C(~N)(~N)
0.0538	SUB288	C-F
PF00217	ATP:guanido phosphotransferase, C-terminal catalytic domain
0.1119	SUB603	O=C-C-N-C
0.1063	SUB597	N=C-N-C-C
0.0548	SUB489	N-C=N-[#1]
0.0430	SUB441	C(-C)(-O)(=O)
PF08070	DTHCT (NUC029),  region
0.1108	SUB249	>= 1 any ring size 10
0.1083	SUB444	C(-C)(=O)
0.0617	SUB182	>= 1 saturated or aromatic heteroatom-containing ring size 6
0.0342	SUB186	>= 2 any ring size 6
0.0168	SUB644	[#1]-C-C-N-[#1]
0.0039	SUB194	>= 3 saturated or aromatic carbon-only ring size 6
PF01210	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
0.1107	SUB613	N-C-O-C-C
0.0857	SUB261	>= 3 hetero-aromatic rings
PF00641	Zn-finger in Ran binding protein and others
0.1104	SUB555	Br-C-C-C
0.0871	SUB510	Br-C:C-C
0.0237	SUB719	Cc1ccc(Br)cc1
0.0111	SUB331	C(~Br)(:C)
PF00479	Glucose-6-phosphate dehydrogenase, NAD binding domain
0.1102	SUB32	>= 2 P
0.0864	SUB568	O-C-C-O
0.0725	SUB664	O-C-C-O-[#1]
0.0407	SUB444	C(-C)(=O)
0.0087	SUB360	C(~C)(:N)(:N)
0.0002	SUB572	[#1]-C-O-[#1]
PF08444	Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
0.1093	SUB537	O=C-C-N
0.1088	SUB567	O-C-C-N
0.0592	SUB529	[#1]-N-C-[#1]
PF00027	Cyclic nucleotide-binding domain
0.1079	SUB656	O-C-C-C:C
0.0990	SUB739	Cc1cc(Cl)ccc1
0.0463	SUB642	O-C-C-C=C
0.0316	SUB340	C(~C)(~C)(~H)(~O)
0.0013	SUB549	O-C-C:C
0.0001	SUB575	O-C-C:C-C
PF06466	PCAF (P300/CBP-associated factor),  N-terminal domain
0.1070	SUB691	O-C-C-C-C-C-O
0.0312	SUB151	>= 2 any ring size 5
PF03530	Calcium-activated SK potassium channel
0.1066	SUB38	>= 1 Cl
0.0623	SUB343	C(~C)(~Cl)
0.0005	SUB295	C-Cl
PF04800	ETC complex I subunit conserved region
0.1054	SUB486	N:C:C:N
0.0849	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF02885	Glycosyl transferase family, helical bundle domain
0.1047	SUB562	Cl-C-C=O
0.0850	SUB633	C-C-O-C:C
PF10509	Galactokinase galactose-binding signature
0.1043	SUB32	>= 2 P
0.0864	SUB398	N(~C)(:C)(:C)
0.0285	SUB389	C(:C)(:N)(:N)
PF01597	Glycine cleavage H-protein
0.1035	SUB537	O=C-C-N
0.0788	SUB529	[#1]-N-C-[#1]
0.0642	SUB567	O-C-C-N
PF00316	Fructose-1-6-bisphosphatase
0.1030	SUB457	P(-O)(=O)
0.0851	SUB315	O-P
0.0848	SUB412	P(~O)(~O)
0.0738	SUB408	O(~C)(~P)
0.0627	SUB613	N-C-O-C-C
0.0441	SUB389	C(:C)(:N)(:N)
0.0339	SUB31	>= 1 P
0.0125	SUB426	P=O
PF02666	Phosphatidylserine decarboxylase
0.1026	SUB457	P(-O)(=O)
0.0934	SUB643	O-C-C-C=O
0.0680	SUB22	>= 8 O
0.0327	SUB31	>= 1 P
0.0252	SUB582	O=C-C-C-O
0.0250	SUB412	P(~O)(~O)
0.0235	SUB315	O-P
0.0088	SUB567	O-C-C-N
PF01437	Plexin repeat
0.1025	SUB771	Nc1c(N)cccc1
0.0800	SUB165	>= 4 any ring size 5
0.0729	SUB263	>= 4 hetero-aromatic rings
0.0542	SUB168	>= 4 saturated or aromatic heteroatom-containing ring size 5
0.0528	SUB717	Cc1ccc(N)cc1
0.0377	SUB738	Cc1cc(N)ccc1
0.0220	SUB708	O=C-C-C-C-C(N)-C
0.0002	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
PF01663	Type I phosphodiesterase / nucleotide pyrophosphatase
0.0976	SUB497	N:N-C-[#1]
0.0866	SUB16	>= 2 N
0.0660	SUB31	>= 1 P
0.0266	SUB426	P=O
0.0041	SUB309	O-H
PF08473	Neuronal voltage-dependent calcium channel alpha 2acd
0.0975	SUB697	C-C-C-C-C-C-C-C
0.0833	SUB683	O-C-C-C-C-N
PF09027	GTPase binding
0.0942	SUB531	N:C-C:C
0.0861	SUB612	N-C-C-N-C
0.0784	SUB151	>= 2 any ring size 5
0.0068	SUB358	C(~C)(:C)(:N)
PF01273	LBP / BPI / CETP family, N-terminal domain
0.0942	SUB14	>= 32 C
0.0270	SUB426	P=O
PF02817	e3 binding domain
0.0913	SUB602	N-C:C:C-N
0.0468	SUB622	N-C:C:C:N
0.0233	SUB379	C(~N)(:C)(:N)
0.0001	SUB389	C(:C)(:N)(:N)
PF03185	Calcium-activated potassium channel, beta subunit
0.0901	SUB648	O=C-N-C-N
PF01591	6-phosphofructo-2-kinase
0.0885	SUB573	N:C:N:C
0.0222	SUB500	N-C:C:N
0.0203	SUB380	C(~N)(:N)
0.0190	SUB439	C(-C)(-N)(=N)
0.0186	SUB485	N-C:N:C
0.0085	SUB390	C(:N)(:N)
0.0063	SUB602	N-C:C:C-N
0.0040	SUB622	N-C:C:C:N
0.0005	SUB154	>= 2 saturated or aromatic heteroatom-containing ring size 5
PF00958	GMP synthase C terminal domain
0.0867	SUB333	C(~C)(~C)
0.0312	SUB354	C(~C)(~S)
PF01202	Shikimate kinase
0.0866	SUB582	O=C-C-C-O
0.0467	SUB643	O-C-C-C=O
PF01033	Somatomedin B domain
0.0852	SUB16	>= 2 N
0.0579	SUB497	N:N-C-[#1]
0.0233	SUB315	O-P
0.0213	SUB31	>= 1 P
0.0105	SUB309	O-H
PF01223	DNA/RNA non-specific endonuclease
0.0802	SUB16	>= 2 N
0.0545	SUB497	N:N-C-[#1]
0.0234	SUB309	O-H
PF00439	Bromodomain
0.0801	SUB335	C(~C)(~C)(~C)(~C)
PF01017	STAT protein, all-alpha domain
0.0798	SUB622	N-C:C:C:N
0.0019	SUB602	N-C:C:C-N
PF00300	Phosphoglycerate mutase family
0.0784	SUB389	C(:C)(:N)(:N)
0.0642	SUB360	C(~C)(:N)(:N)
0.0358	SUB622	N-C:C:C:N
0.0325	SUB602	N-C:C:C-N
0.0198	SUB390	C(:N)(:N)
0.0153	SUB380	C(~N)(:N)
0.0074	SUB439	C(-C)(-N)(=N)
0.0066	SUB505	N:C:N-C
0.0006	SUB613	N-C-O-C-C
PF00613	Phosphoinositide 3-kinase family, accessory domain (PIK domain), 
0.0782	SUB522	C:N-C-[#1]
0.0673	SUB486	N:C:C:N
0.0556	SUB717	Cc1ccc(N)cc1
0.0001	SUB500	N-C:C:N
PF01403	Sema domain
0.0780	SUB738	Cc1cc(N)ccc1
0.0770	SUB168	>= 4 saturated or aromatic heteroatom-containing ring size 5
0.0652	SUB708	O=C-C-C-C-C(N)-C
0.0490	SUB717	Cc1ccc(N)cc1
0.0170	SUB165	>= 4 any ring size 5
0.0050	SUB834	NC1C(N)CCCC1
PF02637	GatB domain
0.0778	SUB686	O=C-C-C-C-N
0.0767	SUB695	O=C-C-C-C-C=O
0.0201	SUB694	O=C-C-C-C-C-O
PF06448	Domain of Unknown Function (DUF1081), 
0.0762	SUB14	>= 32 C
PF01388	ARID/BRIGHT DNA binding domain
0.0757	SUB606	O=C-C-O-C
PF08544	GHMP kinases C terminal 
0.0736	SUB398	N(~C)(:C)(:C)
0.0603	SUB32	>= 2 P
0.0520	SUB389	C(:C)(:N)(:N)
PF00094	von Willebrand factor type D domain
0.0716	SUB743	Oc1cc(N)ccc1
0.0692	SUB704	O-C-C-C-C-C(N)-C
PF10589	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
0.0715	SUB261	>= 3 hetero-aromatic rings
PF02887	Pyruvate kinase, alpha/beta domain
0.0707	SUB538	O=C-C-O
0.0526	SUB463	O-C-C=O
0.0009	SUB342	C(~C)(~C)(~O)
PF01729	Quinolinate phosphoribosyl transferase, C-terminal domain
0.0695	SUB625	O=C-C:C-N
0.0379	SUB540	N=C-C-[#1]
0.0099	SUB577	N=C-C:C-[#1]
PF06831	Formamidopyrimidine-DNA glycosylase H2TH domain
0.0690	SUB640	O-C-C-C-O
0.0012	SUB337	C(~C)(~C)(~C)(~N)
PF00057	Low-density lipoprotein receptor domain class A
0.0688	SUB594	N-C-C-C-N
0.0677	SUB406	O(~C)(~C)
0.0341	SUB684	N-C-C-C-C-C
PF00288	GHMP kinases N terminal domain
0.0673	SUB32	>= 2 P
0.0277	SUB389	C(:C)(:N)(:N)
PF04704	Zfx / Zfy transcription activation region
0.0671	SUB336	C(~C)(~C)(~C)(~H)
0.0495	SUB705	O=C-C-C-C-C-C-C
0.0421	SUB693	O=C-C-C-C-C-C
PF05221	S-adenosyl-L-homocysteine hydrolase
0.0656	SUB572	[#1]-C-O-[#1]
0.0541	SUB602	N-C:C:C-N
0.0379	SUB622	N-C:C:C:N
0.0093	SUB389	C(:C)(:N)(:N)
PF07706	Aminotransferase ubiquitination site
0.0648	SUB690	O-C-C-C-C-C-C
0.0434	SUB453	C(-O)(=O)
0.0348	SUB699	O-C-C-C-C-C-C-C
0.0081	SUB638	O-C-C-C-C
0.0043	SUB618	C-C-C-O-[#1]
0.0007	SUB309	O-H
0.0006	SUB536	O=C-C-C
0.0005	SUB580	O=C-C-C-C
0.0003	SUB583	C-C-C-C-C
0.0001	SUB381	C(~O)(~O)
0.0001	SUB685	O=C-C-C-C-C
PF00458	WHEP-TRS domain
0.0612	SUB567	O-C-C-N
0.0589	SUB537	O=C-C-N
0.0416	SUB401	N(~H)(:C)(:C)
0.0349	SUB528	C:C:N-[#1]
PF03351	DOMON domain
0.0599	SUB664	O-C-C-O-[#1]
PF02928	C5HC2 zinc finger
0.0598	SUB606	O=C-C-O-C
0.0097	SUB582	O=C-C-C-O
PF03483	B3/4 domain
0.0597	SUB537	O=C-C-N
0.0301	SUB567	O-C-C-N
0.0091	SUB339	C(~C)(~C)(~H)(~N)
PF00628	PHD-finger
0.0575	SUB606	O=C-C-O-C
PF00096	Zinc finger, C2H2 type
0.0549	SUB537	O=C-C-N
0.0309	SUB336	C(~C)(~C)(~C)(~H)
0.0246	SUB705	O=C-C-C-C-C-C-C
PF02375	jmjN domain
0.0541	SUB606	O=C-C-O-C
PF10588	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
0.0534	SUB161	>= 3 saturated or aromatic heteroatom-containing ring size 5
PF00794	PI3-kinase family, ras-binding domain
0.0514	SUB522	C:N-C-[#1]
0.0023	SUB500	N-C:C:N
PF03484	tRNA synthetase B5 domain
0.0482	SUB567	O-C-C-N
0.0394	SUB537	O=C-C-N
PF08418	DNA polymerase alpha subunit B N-terminal
0.0476	SUB448	C(-H)(=N)
0.0210	SUB439	C(-C)(-N)(=N)
0.0210	SUB399	N(~H)(~N)
0.0159	SUB523	C-N-N-[#1]
0.0071	SUB301	N-N
PF11825	Protein of unknown function (DUF3345), 
0.0464	SUB441	C(-C)(-O)(=O)
PF00787	PX domain
0.0443	SUB567	O-C-C-N
0.0176	SUB375	C(~H)(~H)(~H)
PF02865	STAT protein, protein interaction domain
0.0420	SUB602	N-C:C:C-N
0.0007	SUB622	N-C:C:C:N
PF00093	von Willebrand factor type C domain
0.0414	SUB702	O-C-C-C-C-C(O)-C
PF10565	N-methyl D-aspartate receptor 2B3 C-terminus
0.0411	SUB407	O(~C)(~H)
0.0320	SUB286	C-N
0.0057	SUB710	C-C(C)-C-C-C
PF02877	Poly(ADP-ribose),  polymerase, regulatory domain
0.0411	SUB625	O=C-C:C-N
PF08833	Axin beta-catenin binding domain
0.0400	SUB35	>= 2 S
PF08063	PADR1 (NUC008),  domain
0.0380	SUB674	O=C-C=C-N
0.0002	SUB625	O=C-C:C-N
PF00384	Molybdopterin oxidoreductase
0.0355	SUB158	>= 3 any ring size 5
PF01411	tRNA synthetases class II (A), 
0.0340	SUB375	C(~H)(~H)(~H)
PF01826	Trypsin Inhibitor like cysteine rich domain
0.0321	SUB462	O-C-C=N
0.0302	SUB653	O-C:C:C-N
0.0111	SUB708	O=C-C-C-C-C(N)-C
PF08264	Anticodon-binding domain
0.0308	SUB336	C(~C)(~C)(~C)(~H)
PF08771	Rapamycin binding domain
0.0257	SUB433	C(-C)(-C)(=O)
0.0002	SUB606	O=C-C-O-C
PF02538	Hydantoinase B/oxoprolinase
0.0239	SUB694	O=C-C-C-C-C-O
PF03104	DNA polymerase family B, exonuclease domain
0.0232	SUB288	C-F
0.0019	SUB24	>= 1 F
PF02260	FATC domain
0.0205	SUB606	O=C-C-O-C
0.0182	SUB433	C(-C)(-C)(=O)
0.0003	SUB189	>= 2 saturated or aromatic heteroatom-containing ring size 6
PF03950	tRNA synthetases class I (E and Q), , anti-codon binding domain
0.0197	SUB692	O-C-C-C-C-C-N
PF09193	Cholecystokinin A receptor, N-terminal
0.0192	SUB409	O(~H)(~S)
0.0001	SUB18	>= 8 N
0.0001	SUB14	>= 32 C
PF08499	3"5"-cyclic nucleotide phosphodiesterase N-terminal
0.0186	SUB35	>= 2 S
PF00004	ATPase family associated with various cellular activities (AAA), 
0.0184	SUB32	>= 2 P
PF11404	Potassium voltage-gated channel
0.0163	SUB31	>= 1 P
0.0096	SUB426	P=O
0.0052	SUB315	O-P
0.0022	SUB408	O(~C)(~P)
0.0015	SUB457	P(-O)(=O)
0.0001	SUB412	P(~O)(~O)
PF00024	PAN domain
0.0155	SUB346	C(~C)(~H)(~N)
0.0086	SUB366	C(~H)(~N)
PF00732	GMC oxidoreductase
0.0153	SUB572	[#1]-C-O-[#1]
PF00533	BRCA1 C Terminus (BRCT),  domain
0.0113	SUB440	C(-C)(-N)(=O)
0.0076	SUB452	C(-N)(=O)
PF01512	Respiratory-chain NADH dehydrogenase 51 Kd subunit
0.0072	SUB261	>= 3 hetero-aromatic rings
PF06464	DMAP1-binding Domain
0.0057	SUB452	C(-N)(=O)
PF07966	A1 Propeptide 
0.0056	SUB594	N-C-C-C-N
0.0003	SUB700	O-C-C-C-C-C(C)-C
PF02373	JmjC domain
0.0014	SUB606	O=C-C-O-C
PF00174	Oxidoreductase molybdopterin binding domain
0.0011	SUB168	>= 4 saturated or aromatic heteroatom-containing ring size 5
0.0001	SUB262	>= 4 aromatic rings
PF00644	Poly(ADP-ribose),  polymerase catalytic domain
0.0006	SUB674	O=C-C=C-N
0.0001	SUB625	O=C-C:C-N
PF00198	2-oxoacid dehydrogenases acyltransferase (catalytic domain), 
0.0005	SUB379	C(~N)(:C)(:N)
PF00289	Carbamoyl-phosphate synthase L chain, N-terminal domain
0.0002	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
PF02864	STAT protein, DNA binding domain
0.0001	SUB622	N-C:C:C:N
PF02786	Carbamoyl-phosphate synthase L chain, ATP binding domain
0.0001	SUB230	>= 1 saturated or aromatic nitrogen-containing ring size 8
PF05406	WGR domain
PF05735	Thrombospondin C-terminal region
PF12491	Apolipoprotein B100 C terminal