Saccharomyces cerevisiae - Functional Catalogue   lipid, fatty-acid and isoprenoid metabolism (213 ORFs) YPL268w PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YML126c ERG13 3-hydroxy-3-methylglutaryl coenzyme A synthase YML075c HMG1 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 YLR450w HMG2 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 YLR100w ERG27 3-keto sterol reductase YBR265w TSC10 3-ketosphinganine reductase YNR008w LRO1 a lecithin cholesterol acyltransferase-like gene, mediates diacylglycerol esterification YKL188c PXA2 ABC transporter, peroxisomal YPL028w ERG10 acetyl-CoA C-acetyltransferase, cytosolic YIL160c POT1 acetyl-CoA C-acyltransferase, peroxisomal YNR016c ACC1 acetyl-CoA carboxylase YBL015w ACH1 acetyl-CoA hydrolase YIL009w FAA3 acyl CoA synthase YGL205w POX1 acyl-CoA oxidase YCR048w ARE1 acyl-CoA sterol acyltransferase YNR019w ARE2 acyl-CoA sterol acyltransferase YGR037c ACB1 acyl-coenzyme-A-binding protein (diazepam binding inhibitor) YBR183w YPC1 Alkaline Ceramidase YPL087w YDC1 alkaline dihydroceramidase YBR222c FAT2 AMP-binding protein, peroxisomal YKL004w AUR1 aureobasidin-resistance protein YDR123c INO2 basic helix-loop-helix (BHLH) transcription factor YOL108c INO4 basic helix-loop-helix transcription factor YER061c CEM1 beta-keto-acyl-ACP synthase, mitochondrial YNL280c ERG24 C-14 sterol reductase YMR015c ERG5 C-22 sterol desaturase YGL001c ERG26 C-3 sterol dehydrogenase (C-4 decarboxylase) YGR060w ERG25 C-4 sterol methyl oxidase YLR056w ERG3 C-5 sterol desaturase YMR202w ERG2 C-8 sterol isomerase YBR036c CSG2 calcium dependent regulatory protein YDL142c CRD1 cardiolipin synthase YAR035w YAT1 carnitine acetyltransferase, mitochondrial YER024w YAT2 carnitine O-acetyltransferase YML042w CAT2 carnitine O-acetyltransferase YPR113w PIS1 CDP diacylglycerol--inositol 3-phosphatidyltransferase YER026c CHO1 CDP-diacylglycerol serine O-phosphatidyltransferase YBR029c CDS1 CDP-diacylglycerol synthase YLR133w CKI1 choline kinase YGR007w MUQ1 choline phosphate cytidylyltransferase YGR202c PCT1 cholinephosphate cytidylyltransferase YNL111c CYB5 cytochrome b5 YHR007c ERG11 cytochrome P450 lanosterol 14a-demethylase YLR284c ECI1 delta3-cis-delta2-trans-enoyl-CoA isomerase YNL130c CPT1 diacylglycerol cholinephosphotransferase YDR284c DPP1 diacylglycerol pyrophosphate phosphatase YDR294c DPL1 dihydrosphingosine phosphate lyase YKR053c YSR3 dihydrosphingosine-1-phosphate phosphatase YMR013c SEC59 dolichol kinase YOR180c DCI1 Enoyl-CoA Hydratase, peroxisomal YDR331w GPI8 essential for GPI anchor attachment YBR067c TIP1 esterase YDR147w EKI1 ethanolamine kinase YDR410c STE14 farnesyl cysteine carboxyl-methyltransferase YPL172c COX10 farnesyl transferase YHR190w ERG9 farnesyl-diphosphate farnesyltransferase YJL167w ERG20 farnesyl-pyrophosphate synthetase YCR034w FEN1 fatty acid elongase required for sphingolipid formation YJL196c ELO1 fatty acid elongation protein YDL052c SLC1 fatty acyltransferase YPL231w FAS2 fatty-acyl-CoA synthase, alpha chain YKL182w FAS1 fatty-acyl-CoA synthase, beta chain YPL069c BTS1 geranylgeranyl diphosphate synthase YJL031c BET4 geranylgeranyl transferase, alpha chain YGL155w CDC43 geranylgeranyltransferase beta subunit YOR370c MRS6 geranylgeranyltransferase regulatory subunit YPR176c BET2 geranylgeranyltransferase type II beta subunit YLL043w FPS1 glycerol channel protein YCR098c GIT1 glycerophosphoinositol transporter YMR307w GAS1 glycophospholipid-anchored surface glycoprotein YDR302w GPI11 GPI11 - protein involved in glycosylphosphatidylinositol (GPI) biosynthesis YFL014w HSP12 heat shock protein YBR003w COQ1 hexaprenyl pyrophosphate synthetase precursor YCR028c FEN2 high affinity H+/pantothenate symporter YKR009c FOX2 hydratase-dehydrogenase-epimerase, peroxisomal YGL162w SUT1 hypoxic protein involved in sterol uptake YGL126w SCS3 inositol phospholipid synthesis protein YOL065c INP54 inositol polyphosphate 5-phosphatase YOR237w HES1 involved in ergosterol biosynthesis YPL145c KES1 involved in ergosterol biosynthesis YCL026c-a FRM2 involved in fatty acid regulation YNL264c PDR17 involved in regulating phosphatidylserine metabolism YER044c ERG28 involved in synthesis of ergosterol YKL213c DOA1 involved in ubiquitin-dependent proteolysis YNL009w IDP3 isocitrate dehydrogenase, NADP-dependent YPL117c IDI1 isopentenyl-diphosphate delta-isomerase YHR072w ERG7 lanosterol synthase YDR503c LPP1 lipid phosphate phosphatase YPL147w PXA1 long-chain fatty acid transporter YER015w FAA2 long-chain-fatty-acid--CoA ligase YMR246w FAA4 long-chain-fatty-acid--CoA ligase YOR317w FAA1 long-chain-fatty-acid--CoA ligase YDL078c MDH3 malate dehydrogenase, peroxisomal YOR221c MCT1 malonyl-CoA:ACP transferase YDR072c IPT1 mannosyl diphosphorylinositol ceramide synthase YNL219c ALG9 mannosyltransferase YJR073c OPI3 methylene-fatty-acyl-phospholipid synthase YMR208w ERG12 mevalonate kinase YNR043w MVD1 mevalonate pyrophosphate decarboxylase YMR060c TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YDR376w ARH1 mitochondrial protein with similarity to human adrenodoxin reductase and ferredoxin-NADP+ reductase YKL192c ACP1 mitochonrial acyl-carrier protein YDR011w SNQ2 multidrug resistance protein YDR497c ITR1 myo-inositol permease, major YOL103w ITR2 myo-inositol permease, minor YMR281w GPI12 N-acetylglucosaminyl phosphatidylinositol deacetylase YPL076w GPI2 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein YPL175w SPT14 N-acetylglucosaminyltransferase YLR195c NMT1 N-myristoyltransferase YHR042w NCP1 NADPH-cytochrome P450 reductase YHL020c OPI1 negative regulator of phospholipid biosynthesis pathway YDR207c UME6 negative transcriptional regulator YAL051w OAF1 peroxisome proliferating transcription factor YOR363c PIP2 peroxisome proliferating transcription factor YGR157w CHO2 phosphatidylethanolamine N-methyltransferase YCL004w PGS1 phosphatidylglycerophosphate synthase YJR066w TOR1 phosphatidylinositol 3-kinase YKL203c TOR2 phosphatidylinositol 3-kinase YLR240w VPS34 phosphatidylinositol 3-kinase YFR019w FAB1 phosphatidylinositol 3-phosphate 5-kinase YNL267w PIK1 phosphatidylinositol 4-kinase YIL002c INP51 phosphatidylinositol phosphate 5-phosphatase YNL106c INP52 phosphatidylinositol phosphate phosphatase YOR109w INP53 phosphatidylinositol phosphate phosphatase YDR313c PIB1 phosphatidylinositol(3)-phosphate binding protein YMR079w SEC14 phosphatidylinositol(PI)/phosphatidylcholine(PC) transfer protein YLR305c STT4 phosphatidylinositol-4-kinase YDR208w MSS4 phosphatidylinositol-4-phosphate 5-kinase YNL169c PSD1 phosphatidylserine decarboxylase 1 YGR170w PSD2 phosphatidylserine decarboxylase 2 YMR008c PLB1 phospholipase B (lysophospholipase) YOL011w PLB3 phospholipase B (lysophospholipase) YKR031c SPO14 phospholipase D YMR220w ERG8 phosphomevalonate kinase YPL148c PPT2 phosphopantetheine protein transferase YOR153w PDR5 pleiotropic drug resistance protein YCL043c PDI1 protein disulfide-isomerase precursor YKL019w RAM2 protein farnesyltransferase, alpha subunit YDL090c RAM1 protein farnesyltransferase, beta subunit YNL231c PDR16 protein involved in lipid biosynthesis and multidrug resistance YHR079c IRE1 protein kinase YDL040c NAT1 protein N-acetyltransferase subunit YHR013c ARD1 protein N-acetyltransferase subunit YKL055c OAR1 putative 3-oxoacyl-(acyl carrier protein) reductase YAL013w DEP1 regulator of phospholipid metabolism YDR213w UPC2 regulatory protein involved in control of sterol uptake YLR088w GAA1 required for attachment of GPI anchor onto proteins YDL015c TSC13 required for elongation of the very long chain fatty acid (VLCFA) moiety of sphingolipids YGL142c GPI10 required for Glycosyl Phosphatdyl Inositol synthesis YMR272c SCS7 required for hydroxylation of ceramide YPL057c SUR1 required for mannosylation of sphingolipids YGR216c GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YBR058c-a TSC3 required for optimal serine palmitoyltransferase activity YDR297w SUR2 required for the hydroxylation of C-4 of the sphingoid moiety of ceramide YML008c ERG6 S-adenosyl-methionine delta-24-sterol-c-methyltransferase YDR062w LCB2 serine C-palmitoyltransferase subunit YMR296c LCB1 serine C-palmitoyltransferase subunit YBR263w SHM1 serine hydroxymethyltransferase precursor, mitochondrial YLR058c SHM2 serine hydroxymethyltransferase, cytoplasmic YKL174c similarity to choline transport protein HNM1P YNR056c BIO5 similarity to choline transport protein HNM1P YBR159w similarity to human 17-beta-hydroxysteroid dehydrogenase YIR035c similarity to human corticosteroid 11-beta-dehydrogenase YML131w similarity to human leukotriene b4 12-hydroxydehydrogenase YAR044w OSH1 similarity to human oxysterol binding protein (OSBP) YPL006w NCR1 similarity to human PTC protein involved in nevoid basal cell carcinoma syndrome YDR452w PHM5 similarity to human sphingomyelin phosphodiesterase (PIR:S06957) YDR444w similarity to hypothetical protein YGL144c and YDL109c YDR287w similarity to inositolmonophosphatases YHR046c similarity to inositolmonophosphatases YHR001w OSH7 similarity to KES1P YKR003w OSH6 similarity to KES1P, HES1P and OSH1P YPR048w TAH18 similarity to M.domestica NADPH--ferrihemoprotein reductase and mammalian nitric-oxide synthases YAR042w SWH1 similarity to mammalian oxysterol-binding proteins YHR073w OSH3 similarity to OSH1P, YDL019c and mammalian oxysterol-binding protei YDL019c OSH2 similarity to SWH1P YLR020c similarity to triacylglycerol lipase YLL012w similarity to triacylglycerol lipases YLR099c ICT1 similarity to YDR125c YHR123w EPT1 sn-1,2-diacylglycerol ethanolamine- and cholinephosphotransferase YJL134w LCB3 sphingoid base-phosphate phosphatase YLR260w LCB5 sphingolipid long chain base kinase YOR171c LCB4 sphingolipid long chain base kinase YGR175c ERG1 squalene monooxygenase YGL055w OLE1 stearoyl-CoA desaturase YGL012w ERG4 sterol C-24 reductase YLR189c UGT51 sterol glucosyltransferase (UDP-glucose:sterol glucosyltransferase) YLR372w SUR4 sterol isomerase, fatty acid elongase YMR207c HFA1 strong similarity to acetyl-CoA carboxylase YJL068c strong similarity to human esterase D YNL045w strong similarity to human leukotriene-A4 hydrolase YGL144c strong similarity to hypothetical protein YDL109c YDL109c strong similarity to hypothetical protein YGL144c YMR006c PLB2 strong similarity to PLB1P, YOL011w and P.notatum lysophospholipase YKL091c strong similarity to SEC14P YMR020w FMS1 suppressor of fenpropimorph resistance mutation FEN2 YBL088c TEL1 telomere length control protein YFL031w HAC1 transcription factor YMR043w MCM1 transcription factor of the MADS box family YOL004w SIN3 transcription regulatory protein YNL012w SPO1 transcriptional regulator involved in sporulation YDR058c TGL2 triacylglycerol lipase YKL140w TGL1 triacylglycerol lipase YBR041w FAT1 very long-chain fatty acyl-CoA synthetase YBR042c CST26 weak similarity to 1-acyl-sn-glycerol-3-phosphate acyltransferase from Brassica napus YJR107w weak similarity to acylglycerol lipase YER019w ISC1 weak similarity to human and mouse neutral sphingomyelinase YJL132w weak similarity to human phospholipase D YNL040w weak similarity to M.genitalium alanine--tRNA ligase YBR204c weak similarity to peroxisomal serine-active lipase YLR380w CSR1 weak similarity to SEC14 protein YJL145w weak similarity to T.pacificus retinal-binding protein YLL048c YBT1 yeast bile transporter Back to MIPS Yeast Functional Categories Page. Back to MIPS Genome Project Page. Back to MIPS Homepage. mail questions/comments to webmaster