Saccharomyces cerevisiae -
Functional Catalogue

mips


 

lipid, fatty-acid and isoprenoid biosynthesis (118 ORFs)

YML126c     ERG13    3-hydroxy-3-methylglutaryl coenzyme A synthase
YML075c     HMG1     3-hydroxy-3-methylglutaryl-coenzyme A reductase 1
YLR450w     HMG2     3-hydroxy-3-methylglutaryl-coenzyme A reductase 2
YLR100w     ERG27    3-keto sterol reductase
YBR265w     TSC10    3-ketosphinganine reductase
YNR008w     LRO1     a lecithin cholesterol acyltransferase-like gene, mediates diacylglycerol esterification
YPL028w     ERG10    acetyl-CoA C-acetyltransferase, cytosolic
YNR016c     ACC1     acetyl-CoA carboxylase
YIL009w     FAA3     acyl CoA synthase
YCR048w     ARE1     acyl-CoA sterol acyltransferase
YNR019w     ARE2     acyl-CoA sterol acyltransferase
YGR037c     ACB1     acyl-coenzyme-A-binding protein (diazepam binding inhibitor)
YBR183w     YPC1     Alkaline Ceramidase
YBR222c     FAT2     AMP-binding protein, peroxisomal
YKL004w     AUR1     aureobasidin-resistance protein
YER061c     CEM1     beta-keto-acyl-ACP synthase, mitochondrial
YNL280c     ERG24    C-14 sterol reductase
YMR015c     ERG5     C-22 sterol desaturase
YGL001c     ERG26    C-3 sterol dehydrogenase (C-4 decarboxylase)
YGR060w     ERG25    C-4 sterol methyl oxidase
YLR056w     ERG3     C-5 sterol desaturase
YMR202w     ERG2     C-8 sterol isomerase
YDL142c     CRD1     cardiolipin synthase
YML042w     CAT2     carnitine O-acetyltransferase
YPR113w     PIS1     CDP diacylglycerol--inositol 3-phosphatidyltransferase
YER026c     CHO1     CDP-diacylglycerol serine O-phosphatidyltransferase
YBR029c     CDS1     CDP-diacylglycerol synthase
YLR133w     CKI1     choline kinase
YGR007w     MUQ1     choline phosphate cytidylyltransferase
YGR202c     PCT1     cholinephosphate cytidylyltransferase
YNL111c     CYB5     cytochrome b5
YHR007c     ERG11    cytochrome P450 lanosterol 14a-demethylase
YNL130c     CPT1     diacylglycerol cholinephosphotransferase
YDR294c     DPL1     dihydrosphingosine phosphate lyase
YKR053c     YSR3     dihydrosphingosine-1-phosphate phosphatase
YDR147w     EKI1     ethanolamine kinase
YHR190w     ERG9     farnesyl-diphosphate farnesyltransferase
YJL167w     ERG20    farnesyl-pyrophosphate synthetase
YCR034w     FEN1     fatty acid elongase required for sphingolipid formation
YJL196c     ELO1     fatty acid elongation protein
YDL052c     SLC1     fatty acyltransferase
YPL231w     FAS2     fatty-acyl-CoA synthase, alpha chain
YKL182w     FAS1     fatty-acyl-CoA synthase, beta chain
YPL069c     BTS1     geranylgeranyl diphosphate synthase
YGL126w     SCS3     inositol phospholipid synthesis protein
YOR237w     HES1     involved in ergosterol biosynthesis
YPL145c     KES1     involved in ergosterol biosynthesis
YNL264c     PDR17    involved in regulating phosphatidylserine metabolism
YER044c     ERG28    involved in synthesis of ergosterol
YPL117c     IDI1     isopentenyl-diphosphate delta-isomerase
YHR072w     ERG7     lanosterol synthase
YMR246w     FAA4     long-chain-fatty-acid--CoA ligase
YOR317w     FAA1     long-chain-fatty-acid--CoA ligase
YOR221c     MCT1     malonyl-CoA:ACP transferase
YDR072c     IPT1     mannosyl diphosphorylinositol ceramide synthase
YNL219c     ALG9     mannosyltransferase
YJR073c     OPI3     methylene-fatty-acyl-phospholipid synthase
YNR043w     MVD1     mevalonate pyrophosphate decarboxylase
YMR060c     TOM37    mitochondrial outer membrane import receptor subunit, 37 kD
YDR376w     ARH1     mitochondrial protein with similarity to human adrenodoxin reductase and ferredoxin-NADP+ reductase
YKL192c     ACP1     mitochonrial acyl-carrier protein
YMR281w     GPI12    N-acetylglucosaminyl phosphatidylinositol deacetylase
YPL076w     GPI2     N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein
YPL175w     SPT14    N-acetylglucosaminyltransferase
YHR042w     NCP1     NADPH-cytochrome P450 reductase
YGR157w     CHO2     phosphatidylethanolamine N-methyltransferase
YCL004w     PGS1     phosphatidylglycerophosphate synthase
YJR066w     TOR1     phosphatidylinositol 3-kinase
YKL203c     TOR2     phosphatidylinositol 3-kinase
YLR240w     VPS34    phosphatidylinositol 3-kinase
YFR019w     FAB1     phosphatidylinositol 3-phosphate 5-kinase
YNL267w     PIK1     phosphatidylinositol 4-kinase
YIL002c     INP51    phosphatidylinositol phosphate 5-phosphatase
YDR313c     PIB1     phosphatidylinositol(3)-phosphate binding protein
YLR305c     STT4     phosphatidylinositol-4-kinase
YDR208w     MSS4     phosphatidylinositol-4-phosphate 5-kinase
YNL169c     PSD1     phosphatidylserine decarboxylase 1
YGR170w     PSD2     phosphatidylserine decarboxylase 2
YMR220w     ERG8     phosphomevalonate kinase
YPL148c     PPT2     phosphopantetheine protein transferase
YDL015c     TSC13    required for elongation of the very long chain fatty acid (VLCFA) moiety of sphingolipids
YGL142c     GPI10    required for Glycosyl Phosphatdyl Inositol synthesis
YMR272c     SCS7     required for hydroxylation of ceramide
YPL057c     SUR1     required for mannosylation of sphingolipids
YGR216c     GPI1     required for N-acetylglucosaminyl phosphatidylinositol synthesis
YBR058c-a   TSC3     required for optimal serine palmitoyltransferase activity
YDR297w     SUR2     required for the hydroxylation of C-4 of the sphingoid moiety of ceramide
YML008c     ERG6     S-adenosyl-methionine delta-24-sterol-c-methyltransferase
YDR062w     LCB2     serine C-palmitoyltransferase subunit
YMR296c     LCB1     serine C-palmitoyltransferase subunit
YBR263w     SHM1     serine hydroxymethyltransferase precursor, mitochondrial
YLR058c     SHM2     serine hydroxymethyltransferase, cytoplasmic
YBR159w              similarity to human 17-beta-hydroxysteroid dehydrogenase
YIR035c              similarity to human corticosteroid 11-beta-dehydrogenase
YML131w              similarity to human leukotriene b4 12-hydroxydehydrogenase
YAR044w     OSH1     similarity to human oxysterol binding protein (OSBP)
YDR287w              similarity to inositolmonophosphatases
YHR046c              similarity to inositolmonophosphatases
YHR001w     OSH7     similarity to KES1P
YKR003w     OSH6     similarity to KES1P, HES1P and OSH1P
YPR048w     TAH18    similarity to M.domestica NADPH--ferrihemoprotein reductase and mammalian nitric-oxide synthases
YAR042w     SWH1     similarity to mammalian oxysterol-binding proteins
YHR073w     OSH3     similarity to OSH1P, YDL019c and mammalian  oxysterol-binding protei
YDL019c     OSH2     similarity to SWH1P
YHR123w     EPT1     sn-1,2-diacylglycerol ethanolamine- and cholinephosphotransferase
YJL134w     LCB3     sphingoid base-phosphate phosphatase
YLR260w     LCB5     sphingolipid long chain base kinase
YOR171c     LCB4     sphingolipid long chain base kinase
YGR175c     ERG1     squalene monooxygenase
YGL055w     OLE1     stearoyl-CoA desaturase
YGL012w     ERG4     sterol C-24 reductase
YLR189c     UGT51    sterol glucosyltransferase (UDP-glucose:sterol glucosyltransferase)
YLR372w     SUR4     sterol isomerase, fatty acid elongase
YMR207c     HFA1     strong similarity to acetyl-CoA carboxylase
YNL045w              strong similarity to human leukotriene-A4 hydrolase
YBL088c     TEL1     telomere length control protein
YBR042c     CST26    weak similarity to 1-acyl-sn-glycerol-3-phosphate acyltransferase from Brassica napus
YER019w     ISC1     weak similarity to human and mouse neutral sphingomyelinase

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