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Saccharomyces cerevisiae - Functional Catalogue |
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recombination and DNA repair (99 ORFs)
YGL127c SOH1 allows HPR1 null mutant to grow at 37 deg. YGL213c SKI8 antiviral protein of the beta-transducin (WD-40) repeat family YHL022c SPO11 catalytic subunit of the meiotic double strand break transesterase YBR136w MEC1 cell cycle checkpoint protein YDR499w LCD1 cell cycle checkpoint protein YER173w RAD24 cell cycle checkpoint protein YDR182w CDC1 cell division control protein YMR106c YKU80 component of DNA end-joining repair pathway YKL011c CCE1 cruciform-cutting endonuclease, mitochondrial YPL194w DDC1 DNA damage checkpoint protein YER176w ECM32 DNA dependent ATPase/DNA helicase B YLR032w RAD5 DNA helicase YMR190c SGS1 DNA helicase YML061c PIF1 DNA helicase involved in mitochondrial DNA repair and telomere length YHR031c RRM3 DNA helicase involved in rDNA replication and Ty1 transposition YDL164c CDC9 DNA ligase YOR005c DNL4 DNA ligase IV YGL090w LIF1 DNA ligase IV interacting factor YCR092c MSH3 DNA mismatch repair protein YDR097c MSH6 DNA mismatch repair protein YMR167w MLH1 DNA mismatch repair protein YNL082w PMS1 DNA mismatch repair protein YOL090w MSH2 DNA mismatch repair protein YHR120w MSH1 DNA mismatch repair protein, mitochondrial YCR014c POL4 DNA polymerase YMR224c MRE11 DNA repair and meiotic recombination protein YJR035w RAD26 DNA repair and recombination protein YDR217c RAD9 DNA repair checkpoint protein YCR066w RAD18 DNA repair protein YDR004w RAD57 DNA repair protein YDR076w RAD55 DNA repair protein YDR369c XRS2 DNA repair protein YEL019c MMS21 DNA repair protein YER095w RAD51 DNA repair protein YML095c RAD10 DNA repair protein YNL250w RAD50 DNA repair protein YAR007c RFA1 DNA replication factor A, 69 KD subunit YDR110w FOB1 DNA replication fork blocking protein YOL006c TOP1 DNA topoisomerase I YNL088w TOP2 DNA topoisomerase II (ATP-hydrolysing) YGL163c RAD54 DNA-dependent ATPase of the SNF2P family YFR023w PES4 DNA-directed DNA polymerase epsilon suppressor YPL167c REV3 DNA-directed DNA polymerase zeta subunit YKR056w RNC1 endo-exonuclease YOR033c EXO1 exonuclease which interacts with MSH2P YLR288c MEC3 G2-specific checkpoint protein YMR072w ABF2 high mobility group protein YMR284w YKU70 high-affinity DNA-binding protein YDR138w HPR1 hyperrecombination protein related to TOP1P YPL164c MLH3 insertion and deletion mismatch repair protein YDR296w MHR1 Involved in mitochondrial homologous DNA recombination YGL025c PGD1 mediator complex subunit YER179w DMC1 meiosis-specific protein YFL003c MSH4 meiosis-specific protein YHR157w REC104 meiosis-specific protein YIL072w HOP1 meiosis-specific protein YLR263w RED1 meiosis-specific protein YPL121c MEI5 meiotic protein YGL175c SAE2 meiotic recombination protein YHR086w NAM8 meiotic recombination protein YJR021c REC107 meiotic recombination protein YLR329w REC102 meiotic recombination protein YNL210w MER1 meiotic recombination protein YBR272c HSM3 mismatch repair protein YGL173c KEM1 multifunctional nuclease YNL339c YRF1-6 nearly identical to other subtelomerically encoded putative helicases YBR114w RAD16 nucleotide excision repair protein YJR043c POL32 polymerase-associated gene, third (55 kDa) subunit of DNA polymerase delta YBR088c POL30 Proliferating Cell Nuclear Antigen (PCNA) YML058w SML1 protein inhibitor of ribonucleotide reductase YOL142w RRP40 protein involved in ribosomal RNA processing, component of the exosome complex responsible for 3' end processing and degradation of many RNA species YDR030c RAD28 protein involved in the same pathway as RAD26P, has beta-transducin (WD-40) repeats YLR394w CST9 protein required for synapsis, meiotic recombination, sporulation, proper chromosome segregation, and synaptonemal complex formation YLR466w YRF1-4 protein with similarity to other subtelomerically-coded Y'-helicase proteins YBR098w MMS4 putative transcriptional (co)activator for DNA damage YDL059c RAD59 recombination and DNA repair protein YML032c RAD52 recombination and DNA repair protein YLR383w RHC18 recombination repair protein YGL249w ZIP2 required for meiotic recombination and disjunction YBR073w RDH54 required for mitotic diploid-specific recombination and repair and meiosis YGR180c RNR4 ribonucleotide reductase small subunit YIL066c RNR3 ribonucleotide reductase, repair inducible large subunit YMR228w MTF1 RNA polymerase specific factor, mitochondrial YOR351c MEK1 ser/thr protein kinase YPL153c RAD53 ser/thr/tyr protein kinase YDR227w SIR4 silencing regulatory and DNA-repair protein YLR442c SIR3 silencing regulatory and DNA-repair protein YDL042c SIR2 silencing regulatory protein and DNA-repair protein YOR077w RTS2 similarity to mouse KIN17 protein YOL034w similarity to S.pombe RAD18 and rpgL29 genes and other members of the SMC superfamily YGL043w DST1 TFIIS (transcription elongation factor) YNL273w TOF1 topoisomerase I interacting factor 1 YCR077c PAT1 topoisomerase II-associated protein YGR063c SPT4 transcription elongation protein YGR116w SPT6 transcription elongation protein YLR182w SWI6 transcription factor YML021c UNG1 uracil-DNA glycosylase YDR545w YRF1-1 Y'-helicase protein 1 YER190w YRF1-2 Y'-helicase protein 1
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