Saccharomyces cerevisiae - Functional Catalogue   TRANSCRIPTION (787 ORFs) YIL075c RPN2 26S proteasome regulatory subunit YOR259c RPT4 26S proteasome regulatory subunit YMR287c MSU1 3'-5' exonuclease for RNA 3' ss-tail, mitochondrial YGR195w SKI6 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YHR069c RRP4 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOL021c DIS3 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOR048c RAT1 5'-3' exoribonuclease YBL074c AAR2 A1 cistron splicing factor YMR164c MSS11 activator of STA1, STA2, and STA3 YGL127c SOH1 allows HPR1 null mutant to grow at 37 deg. YHR193c EGD2 alpha subunit of the nascent polypeptide-associated complex YDR252w BTT1 alternate beta subunit of the nascent polypeptide-associated complex YDL197c ASF2 anti-silencing protein YJL115w ASF1 anti-silencing protein YBR120c CBP6 apo-cytochrome B pre-mRNA processing protein YJL209w CBP1 apo-cytochrome b pre-mRNA processing protein YKL208w CBT1 apo-cytochrome b pre-mRNA processing protein YHL038c CBP2 apo-cytochrome b pre-mRNA processing protein 2 YDR173c ARG82 arginine metabolism transcription factor YKL112w ABF1 ARS-binding factor YOR113w AZF1 asparagine-rich zinc finger protein YLR298c YHC1 associated with the U1 snRNP complex YER029c SMB1 associated with U1 snRNP as part of the Sm-core that is common to all spliceosomal snRNPs YGR013w SNU71 associated with U1 snRNP, no counterpart in mammalian U1 snRNP YFL028c CAF16 ATP-binding cassette transporter family member YBL022c PIM1 ATP-dependent protease, mitochondrial YBR142w MAK5 ATP-dependent RNA helicase YGL171w ROK1 ATP-dependent RNA helicase YOR204w DED1 ATP-dependent RNA helicase YPL119c DBP1 ATP-dependent RNA helicase YNL112w DBP2 ATP-dependent RNA helicase of DEAD box family YFL002c SPB4 ATP-dependent RNA helicase of DEAH box family YPL029w SUV3 ATP-dependent RNA helicase, mitochondrial YDR123c INO2 basic helix-loop-helix (BHLH) transcription factor YOL108c INO4 basic helix-loop-helix transcription factor YOR344c TYE7 basic helix-loop-helix transcription factor YOL067c RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YBL103c RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YLR116w MSL5 branch point bridging protein YGR204w ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGL209w MIG2 C2H2 zinc-finger protein YLR433c CNA1 calcineurin B, catalytic subunit YML057w CMP2 calcineurin B, catalytic subunit YKL190w CNB1 calcineurin B, regulatory subunit YNL027w CRZ1 calcineurin responsive zinc-finger YIL033c BCY1 cAMP dependent protein kinase, regulatory subunit YJL164c TPK1 cAMP-dependent protein kinase 1, catalytic chain YPL203w TPK2 cAMP-dependent protein kinase 2, catalytic chain YKL166c TPK3 cAMP-dependent protein kinase 3, catalytic chain YJL033w HCA4 can suppress the U14 snoRNA rRNA processing function YKL139w CTK1 carboxy-terminal domain (CTD) kinase, alpha subunit YJL006c CTK2 carboxy-terminal domain (CTD) kinase, beta subunit YML112w CTK3 carboxy-terminal domain (CTD) kinase, gamma subunit YOR061w CKA2 casein kinase II alpha' chain YOR039w CKB2 casein kinase II beta' chain YGL019w CKB1 casein kinase II, beta subunit YIL035c CKA1 casein kinase II, catalytic alpha chain YBL021c HAP3 CCAAT-binding factor subunit YGL237c HAP2 CCAAT-binding factor subunit YKL109w HAP4 CCAAT-binding factor subunit YOR358w HAP5 CCAAT-binding factor subunit YJR122w CAF17 CCR4 associated factor YKR036c CAF4 CCR4 associated factor YBR215w HPC2 cell cycle regulatory protein YDL220c CDC13 cell division control protein YOL123w HRP1 CF Ib (RNA3' Cleavage factor Ib) YBR195c MSI1 chromatin assembly complex, subunit p50 YML102w CAC2 chromatin assembly complex, subunit p60 YPR018w RLF2 chromatin assembly complex, subunit p90 YLR115w CFT2 cleavage and polyadenylation specificity factor, part of CF II YOR250c CLP1 cleavage/polyadenylation factor IA subunit YNL286w CUS2 cold sensitive U2 snRNA Suppressor YMR288w HSH155 component of a multiprotein splicing factor YGL094c PAN2 component of PAB1P-stimulated poly(A) ribonuclease YDR228c PCF11 component of pre-mRNA 3'-end processing factor CF I YGL044c RNA15 component of pre-mRNA 3'-end processing factor CF I YMR061w RNA14 component of pre-mRNA 3'-end processing factor CF I YJR093c FIP1 component of pre-mRNA polyadenylation factor PF I YLR277c YSH1 component of pre-mRNA polyadenylation factor PF I YPR070w MED1 component of RNA polymerase II holoenzyme and mediator subcomplex YPR056w TFB4 component of RNA polymerase transcription initiation TFIIH factor YNR023w SNF12 component of SWI/SNF global transcription activator complex YOR290c SNF2 component of SWI/SNF global transcription activator complex YPL016w SWI1 component of SWI/SNF global transcription activator complex YBR289w SNF5 component of SWI/SNF transcription activator complex YDR073w SNF11 component of SWI/SNF transcription activator complex YCR042c TSM1 component of TFIID complex YHR099w TRA1 component of the Ada-Spt transcriptional regulatory complex YPR072w NOT5 component of the NOT protein complex YKL025c PAN3 component of the PAB1P-dependent poly(A) ribonuclease YPL011c TAF47 component of the TBP-associated protein complex YHR148w IMP3 component of the U3 small nucleolar ribonucleoprotein YJR002w MPP10 component of the U3 small nucleolar ribonucleoprotein YNL075w IMP4 component of the U3 small nucleolar ribonucleoprotein YEL026w SNU13 component of the U4/U6.U5 snRNP YLR192c HCR1 component of translation initiation factor eIF3, has similarity to human eIF3 p35 subunit YOR308c SNU66 component of U4/U6.U5 snRNP YGL166w CUP2 copper-dependent transcription factor YNL232w CSL4 core component of the 3'-5' exosome Q0050 AI1 COX1 intron 1 protein Q0055 AI2 COX1 intron 2 protein YNL167c SKO1 cre-binding bzip protein YOL001w PHO80 cyclin YPL042c SSN3 cyclin-dependent CTD kinase YPL031c PHO85 cyclin-dependent protein kinase YDL108w KIN28 cyclin-dependent ser/thr protein kinase YDR334w SWR1 DEAH-box protein, putative RNA helicase YNL186w UBP10 derepression of telomeric silencing YLR226w BUR2 divergent CDK-cyclin complex Q0060 AI3 DNA endonuclease Q0065 AI4 DNA endonuclease Q0070 AI5_ALPHA DNA endonuclease AI5_ALPHA Q0160 SCEI DNA endonuclease in 21S rRNA intron YIL143c SSL2 DNA helicase YER171w RAD3 DNA helicase/ATPase YER129w PAK1 DNA polymerase alpha suppressing protein kinase YDR121w DPB4 DNA polymerase II (epsilon) 4th subunit YDR217c RAD9 DNA repair checkpoint protein YOL006c TOP1 DNA topoisomerase I YNL216w RAP1 DNA-binding protein with repressor and activator activity YKL144c RPC25 DNA-direcred RNA polymerase III, 25 KD subunit YOR210w RPB10 DNA-directed polymerase I, II, III 8.3 subunit YNL248c RPA49 DNA-directed RNA polymerase A (I) chain, 46 kDa YJR063w RPA12 DNA-directed RNA polymerase I, 13.7 KD subunit YPR010c RPA135 DNA-directed RNA polymerase I, 135 KD subunit YOR341w RPA190 DNA-directed RNA polymerase I, 190 KD alpha subunit YOR340c RPA43 DNA-directed RNA polymerase I, 36 KD subunit YDR156w RPA14 DNA-directed RNA polymerase I, A14 subunit YOR224c RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YPR187w RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YBR154c RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YPR110c RPC40 DNA-directed RNA polymerase I, III 40 KD subunit YNL113w RPC19 DNA-directed RNA polymerase I,III 16 KD subunit YLR418c CDC73 DNA-directed RNA polymerase II accessory protein YNL025c SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YDR308c SRB7 DNA-directed RNA polymerase II holoenzyme and kornberg's mediator (SRB) subcomplex subunit YER022w SRB4 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YGR104c SRB5 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YHR041c SRB2 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL051w GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YCR081w SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR443c SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YLR071c RGR1 DNA-directed RNA polymerase II holoenzyme subunit YBR279w PAF1 DNA-directed RNA polymerase II regulator YOL005c RPB11 DNA-directed RNA polymerase II subunit, 13.6 kD YBR253w SRB6 DNA-directed RNA polymerase II suppressor protein YGL070c RPB9 DNA-directed RNA polymerase II, 14.2 KD subunit YOR151c RPB2 DNA-directed RNA polymerase II, 140 kDa chain YDR404c RPB7 DNA-directed RNA polymerase II, 19 KD subunit YDL140c RPO21 DNA-directed RNA polymerase II, 215 KD subunit YJL140w RPB4 DNA-directed RNA polymerase II, 32 kDa subunit YOR207c RET1 DNA-directed RNA polymerase III, 130 KD subunit YOR116c RPO31 DNA-directed RNA polymerase III, 160 KD subunit YNL151c RPC31 DNA-directed RNA polymerase III, 31 KD subunit YNR003c RPC34 DNA-directed RNA polymerase III, 34 KD subunit YDL150w RPC53 DNA-directed RNA polymerase III, 47 KD subunit YPR190c RPC82 DNA-directed RNA polymerase III, 82 KD subunit YFL036w RPO41 DNA-directed RNA polymerase, mitochondrial YHR143w-a RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YIL021w RPB3 DNA-directed RNA-polymerase II, 45 kDa YGL251c HFM1 DNA/RNA helicase YGL208w SIP2 dominant suppressor of some ts mutations in RPO21 and PRP4 YOR047c STD1 dosage-dependent modulator of glucose repression YKL020c SPT23 dosage-dependent suppressor of Ty-induced promotor mutations YMR239c RNT1 double-stranded ribonuclease YDR390c UBA2 E1-like (ubiquitin-activating) enzyme YGL058w RAD6 E2 ubiquitin-conjugating enzyme YPL046c ELC1 Elongin C transcription elongation factor YJL168c SET2 enhancer of zeste-like YDR473c PRP3 essential splicing factor YOR319w HSH49 essential yeast splicing factor YHR154w ESC4 Establishes Silent Chromatin YMR219w ESC1 Establishes Silent Chromatin YPL169c MEX67 factor for nuclear mRNA export YDL014w NOP1 fibrillarin YIL131c FKH1 forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle YER159c BUR6 functional homolog of human NC2alpha YDR397c NCB2 functional homolog of human NC2beta/Dr1 YPL037c EGD1 GAL4 DNA-binding enhancer protein YBR020w GAL1 galactokinase YDR009w GAL3 galactokinase YGL097w SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL207w SPT16 general chromatin factor YIL038c NOT3 general negative regulator of transcription, subunit 3 YBR112c CYC8 general repressor of transcription YCR084c TUP1 general transcription repressor YDR176w NGG1 general transcriptional adaptor or co-activator YDR392w SPT3 general transcriptional adaptor or co-activator YDR448w ADA2 general transcriptional adaptor or co-activator YBR045c GIP1 GLC7-interacting protein YNL236w SIN4 global regulator protein YHL025w SNF6 global transcription activator YER027c GAL83 glucose repression protein YBR212w NGR1 glucose-repressible RNA-binding protein YNL199c GCR2 glycolytic genes transcriptional activator YLR293c GSP1 GTP-binding protein of the ras superfamily YOR185c GSP2 GTP-binding protein of the RAS superfamily YMR235c RNA1 GTPase activating protein YOR076c SKI7 GTPase with function in 3'-to-5' degradation of mRNA YGL073w HSF1 heat shock transcription factor YJR036c HUL4 hect domain E3 ubiquitin-protein ligase YMR290c HAS1 helicase associated with SET1P YPR065w ROX1 heme-dependent transcriptional repressor of hypoxic genes YDR006c SOK1 high copy suppressor of a cyclic AMP-dependent protein kinase mutant YJR147w HMS2 High-copy MEP2 Suppressor YMR070w MOT3 high-copy suppressor of MOT1-SPT3 synthetic lethality YGR252w GCN5 histone acetyltransferase YOR244w ESA1 histone acetyltransferase YEL066w HPA3 histone and other protein acetyltransferase YPR193c HPA2 Histone and other Protein Acetyltransferase YNL021w HDA1 histone deacetylase A YNL330c RPD3 histone deacetylase B YDR225w HTA1 histone H2A YBL003c HTA2 histone H2A.2 YDR224c HTB1 histone H2B YBL002w HTB2 histone H2B.2 YBR010w HHT1 histone H3 YNL031c HHT2 histone H3 YBR009c HHF1 histone H4 YNL030w HHF2 histone H4 YBL008w HIR1 histone transcription regulator YOR038c HIR2 histone transcription regulator YDL106c PHO2 homeodomain protein YML027w YOX1 homoeodomain protein YNL068c FKH2 homology to D.melanogaster forkhead protein YOL055c THI20 hydroxymethylpyrimidine phosphate (HMP-P) kinase YDR138w HPR1 hyperrecombination protein related to TOP1P YKR019c IRS4 Increased rDNA silencing YKL159c RCN1 inhibitor of calcineurin YMR283c RIT1 initiator tRNA phosphoribosyl-transferase YJL089w SIP4 interacts with SNF1 protein kinase YER032w FIR1 interacts with the poly(A) polymerase in the two hybrid system YKL032c IXR1 intrastrand crosslink recognition protein and transcription factor YLL011w SOF1 involved in 18S pre-rRNA production YBR081c SPT7 involved in alteration of transcription start site selection YJR140c HIR3 involved in cell cycle regulation of histone transcription YKR072c SIS2 involved in cell cycle-specific gene expression YHR119w SET1 involved in chromatin-mediated gene regulation YPL177c CUP9 involved in copper homeostasis repression of protein import YER088c DOT6 involved in derepression of telomeric silencing YIL010w DOT5 involved in derepression of telomeric silencing YMR302c PRP12 involved in early maturation of pre-rRNA YDR021w FAL1 involved in maturation of 18S rRNA YIR021w MRS1 involved in mitochondrial RNA splicing of COB mRNA YGR158c MTR3 involved in mRNA transport YIL030c SSM4 involved in mRNA turnover YIL128w MET18 involved in NER repair and RNA polymerase II transcription YOR160w MTR10 involved in nuclear protein import YJL050w MTR4 involved in nucleocytoplasmic transport of mRNA YOR148c SPP2 involved in pre-mRNA processing YLR197w SIK1 involved in pre-rRNA processing YCL031c RRP7 involved in pre-rRNA processing and ribosome assembly YHR006w STP2 involved in pre-tRNA splicing YLR375w STP3 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YDL048c STP4 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YBR257w POP4 involved in processing of tRNAs and rRNAs YDR087c RRP1 involved in processing rRNA precursor species to mature rRNAs YNL282w POP3 involved in processsing of tRNAs and rRNAs YDR439w LRS4 involved in rDNA silencing YNL251c NRD1 involved in regulation of nuclear pre-mRNA abundance YIL046w MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YPR199c ARR1 involved in resistance to arsenic compounds YML049c RSE1 involved in RNA splicing and ER to Golgi transport YGR095c RRP46 involved in rRNA processing YDL153c SAS10 involved in silencing YDR363w ESC2 involved in silencing YMR127c SAS2 involved in silencing at HMR YGR097w ASK10 involved in SKN7P-dependent transcription YPR057w BRR1 involved in snRNP biogenesis YGL120c PRP43 involved in spliceosome disassembly YIR018w YAP5 involved in transcription activation YOL028c YAP7 involved in transcription activation YLR039c RIC1 involved in transcription of ribosomal proteins and ribosomal RNA YNL097c PHO23 involved in transcriptional regulation of PHO5 YGL071w RCS1 iron-regulated transcriptional repressor YNL037c IDH1 isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial YOR136w IDH2 isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial YJR060w CBF1 kinetochore protein YCL037c SRO9 La motif-containing proteins that modulate mRNA translation YMR125w STO1 large subunit of the nuclear cap-binding protein complex CBC YDR159w SAC3 leucine permease transcriptional regulator YLR382c NAM2 leucine--tRNA ligase precursor, mitochondrial YGR100w MDR1 MAC1P interacting protein YBR182c SMP1 MADS-box transcription factor YNL016w PUB1 major polyadenylated RNA-binding protein of nucleus and cytoplasm YBR297w MAL33 maltose fermentation regulatory protein YGR288w MAL13 maltose pathway regulatory protein YCR039c MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040w MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCL066w HMLALPHA1 mating type regulatory protein, silenced copy at HML YIR033w MGA2 may be involved in the remodeling chromatin structure YGL025c PGD1 mediator complex subunit YMR112c MED11 mediator complex subunit YHR086w NAM8 meiotic recombination protein YNL210w MER1 meiotic recombination protein YHL027w RIM101 meiotic regulatory protein YOL135c MED7 member of RNA Polymerase II transcriptional regulation mediator complex YGR056w RSC1 member of RSC complex, which remodels the structure of chromatin YKR008w RSC4 member of RSC complex, which remodels the structure of chromatin YLR357w RSC2 member of RSC complex, which remodels the structure of chromatin YJR032w CPR7 member of the cyclophilin family YLR216c CPR6 member of the cyclophilin family YHR211w FLO5 member of the FLO1P family of flocculation proteins YDR191w HST4 member of the SIR2P family of putative NAD-dependent histone deacetylases YOL148c SPT20 member of the TBP class of SPT proteins that alter transcription site selection YMR021c MAC1 metal binding activator YJL056c ZAP1 metalloregulatory protein involved in zinc-responsive transcriptional regulation YLR131c ACE2 metallothionein expression activator YBL013w FMT1 Methionyl-tRNA Transformylase YMR023c MSS1 mitochondrial GTPase involved in expression of COX1 YJR045c SSC1 mitochondrial heat shock protein 70-related protein YDL044c MTF2 mitochondrial protein involved in mRNA splicing and protein synthesis YBR026c (MRF1) mitochondrial respiratory function protein YBR236c ABD1 mRNA cap methyltransferase YOL149w DCP1 mRNA decapping enzyme YGL130w CEG1 mRNA guanylyltransferase (mRNA capping enzyme, alpha subunit) Q0110 BI2 mRNA maturase BI2 Q0115 BI3 mRNA maturase BI3 Q0120 BI4 mRNA maturase BI4 YER165w PAB1 mRNA polyadenylate-binding protein YKL186c MTR2 mRNA transport protein YKL009w MRT4 mRNA turnover 4 YCR073w-a SOL2 multicopy suppressor of LOS1-1 YNR034w SOL1 multicopy suppressor of LOS1-1 YER161c SPT2 multifunctional HMG-like chromatin protein YGL173c KEM1 multifunctional nuclease YOR298c-a MBF1 multiprotein bridging factor mediates GCN4-dependent transcriptional activation YDR120c TRM1 N2,N2-dimethylguanine tRNA methyltransferase YML051w GAL80 negative regulator for expression of galactose-induced genes YKL185w ASH1 negative regulator of HO transcription YPL139c UME1 negative regulator of meiosis YHL020c OPI1 negative regulator of phospholipid biosynthesis pathway YDR464w SPP41 negative regulator of PRP3 and PRP4 gene expression YGL151w NUT1 negative transcription regulator from artifical reporters YPR168w NUT2 negative transcription regulator from artifical reporters YDR207c UME6 negative transcriptional regulator YER127w LCP5 NGG1P interacting protein YGL221c NIF3 NGG1P-interacting factor 3 YLL036c PRP19 non-snRNP sliceosome component required for DNA repair YJL148w RPA34 nonessential component of RNA-polI YHR170w NMD3 nonsense-mediated mRNA decay protein YMR064w AEP1 nuclear control of ATPase messenger RNA expression protein YGR218w CRM1 nuclear export factor, exportin YGR159c NSR1 nuclear localization sequence binding protein YGL122c NAB2 nuclear poly(A)-binding protein YDR192c NUP42 nuclear pore protein YGL092w NUP145 nuclear pore protein YGL172w NUP49 nuclear pore protein YJL041w NSP1 nuclear pore protein YJL061w NUP82 nuclear pore protein YJR042w NUP85 nuclear pore protein YKL057c NUP120 nuclear pore protein YKL068w NUP100 nuclear pore protein YKR082w NUP133 nuclear pore protein YMR047c NUP116 nuclear pore protein YCR093w CDC39 nuclear protein YGL115w SNF4 nuclear regulatory protein YBR167c POP7 nuclear RNase P subunit YCR018c SRD1 nucleolar protein YDR432w NPL3 nucleolar protein YNL061w NOP2 nucleolar protein YPL043w NOP4 nucleolar protein YDL208w NHP2 nucleolar rRNA processing protein YHR072w-a NOP10 nucleolar rRNA processing protein YHR089c GAR1 nucleolar rRNA processing protein YML065w ORC1 origin recognition complex, 104 KD subunit YHR118c ORC6 origin recognition complex, 50 KD subunit YNL261w ORC5 origin recognition complex, 50 kDa subunit YPR162c ORC4 origin recognition complex, 56 KD subunit YLL004w ORC3 origin recognition complex, 62 kDa subunit YBR060c ORC2 origin recognition complex, 72 kDa subunit YBR233w PBP2 PAB1 binding protein YAL051w OAF1 peroxisome proliferating transcription factor YOR363c PIP2 peroxisome proliferating transcription factor YBL005w PDR3 pleiotropic drug resistance regulatory protein YNL076w MKS1 pleiotropic regulatory factor YKR025w RPC37 Pol III transcription YKR002w PAP1 poly(A) polymerase YPL190c NAB3 polyadenylated RNA-binding protein YNL317w PFS2 polyadenylation factor I subunit 2 required for mRNA 3'-end processing, bridges two mRNA 3'-end processing factors YJL025w RRN7 polymerase I specific transcription initiation factor YKL015w PUT3 positive activator of the proline utilisation pathway YLR430w SEN1 positive effector of tRNA-splicing endonuclease YDL080c THI3 positive regulation factor of thiamin metabolism YGL192w IME4 positive transcription factor for IME2 YDR421w ARO80 positive transcription regulator of ARO9 and ARO10 YHR163w SOL3 possible 6-phosphogluconolactonase YDR017c KCS1 potential transcription factor of the BZIP type YDR301w CFT1 pre-mRNA 3'-end processing factor CF II YBR237w PRP5 pre-mRNA processing RNA-helicase YAL032c PRP45 pre-mRNA splicing factor YDL043c PRP11 pre-mRNA splicing factor YER013w PRP22 pre-mRNA splicing factor YGR075c PRP38 pre-mRNA splicing factor YJL203w PRP21 pre-mRNA splicing factor YJR050w ISY1 pre-mRNA splicing factor YKL074c MUD2 pre-mRNA splicing factor YML046w PRP39 pre-mRNA splicing factor YMR268c PRP24 pre-mRNA splicing factor YDL030w PRP9 pre-mRNA splicing factor (snRNA-associated protein) YDR088c SLU7 pre-mRNA splicing factor affecting 3' splice site choice YDR243c PRP28 pre-mRNA splicing factor RNA helicase of DEAD box family YGR091w PRP31 pre-mRNA splicing protein YLR223c IFH1 pre-rRNA processing machinery control protein YAL043c PTA1 pre-tRNA processing protein / PF I subunit YKL205w LOS1 pre-tRNA splicing protein YDR463w STP1 pre-tRNA splicing protein, transcription factor YDL084w SUB2 probably involved in pre-mRNA splicing YMR229c RRP5 processing of pre-ribosomal RNA YJR017c ESS1 processing/termination factor 1 YPR137w RRP9 protein associated with the U3 small nucleolar RNA, required for pre-ribosomal RNA processing YNL221c POP1 protein component of ribonuclease P and ribonuclease MRP YDR083w RRP8 protein involved in cleavage at site A2 in pre-rRNA in the pathway of ribosomal RNA processing YFL033c RIM15 protein kinase involved in expression of meiotic genes YPR107c YTH1 protein of the 3' processing complex YGL105w ARC1 protein with specific affinity for G4 quadruplex nucleic acids YFL001w DEG1 pseudouridine synthase YNL292w PUS4 pseudouridine synthase YPL212c PUS1 pseudouridine synthase 1 YGL063w PUS2 pseudouridine synthase 2 YLR059c REX2 putative 3'-5' exonuclease YDR395w SXM1 putative beta-karyopherin YGL194c HOS2 putative histone deacetylase YDL098c SNU23 Putative RNA binding zinc finger protein YDL031w DBP10 putative RNA helicase involved in ribosome biogenesis YDL160c DHH1 putative RNA helicase of the DEAD box family YGL078c DBP3 putative RNA helicase required for pre-rRNA processing YLR175w CBF5 putative rRNA pseuduridine synthase YBL066c SEF1 putative transcription factor YDR002w YRB1 ran-specific GTPase-activating protein YBR275c RIF1 RAP1-interacting factor 1 YGL244w RTF1 regulates DNA binding properties of TBP YCL017c NFS1 regulates Iron-Sulfur cluster proteins, cellular Iron uptake, andIron distribution YFR029w PTR3 regulator of expression of the PTR2, GAP1 and BAP2 genes YKL038w RGT1 regulator of glucose-induced genes YOR294w RRS1 regulator of ribosome synthesis YBR240c THI2 regulator of the thiamine biosynthetic genes YDR257c RMS1 regulatory protein YNL139c RLR1 regulatory protein YMR016c SOK2 regulatory protein in the PKA signal transduction pathway YDR213w UPC2 regulatory protein involved in control of sterol uptake YCL055w KAR4 regulatory protein required for pheromone induction of karyogamy genes YDR028c REG1 regulatory subunit for protein phosphatase GLC7P YLR176c RFX1 repressor of DNA damage-inducible genes YIL106w MOB1 required for completion of mitosis and maintenance of ploidy YER109c FLO8 required for diploid filamentous growth YPL211w NIP7 required for efficient 60S ribosome subunit biogenesis YNR052c POP2 required for glucose derepression YER120w SCS2 required for inositol metabolism YHR065c RRP3 required for maturation of the 35S primary transcript YMR179w SPT21 required for normal transcription at a number of loci YER107c GLE2 required for nuclear pore complex structure and function YKL093w MBR1 required for optimal growth on glycerol YOR310c NOP58 required for pre-18S rRNA processing YKL172w EBP2 required for pre-rRNA processing and ribosomal subunit assembly YHR062c RPP1 required for processing of tRNA and 35S rRNA YAL033w POP5 required for processing of tRNAs and rRNAs YBL018c POP8 required for processing of tRNAs and rRNAs YGR030c POP6 required for processing of tRNAs and rRNAs YJL076w NET1 required for rDNA silencing and nucleolar integrity YCL054w SPB1 required for ribosome synthesis, putative methylase YLR067c PET309 required for stability and translation of COX1 mRNA YIR011c STS1 required for transport of RNA15P from the cytoplasm to the nucleus YML091c RPM2 ribonuclease P precursor, mitochondrial YDR195w REF2 RNA 3'-end formation protein YPL228w CET1 RNA 5'-triphosphatase (mRNA capping enzyme, beta subunit) YMR180c CTL1 RNA 5'-triphosphatase with manganese- or cobalt-dependent NTPase activities YDR381w YRA1 RNA annealing protein YDL051w LHP1 RNA binding protein YDR478w SNM1 RNA binding protein of RNase MRP YLR107w REX3 RNA exonuclease, member of the family of 3' -5' exonucleases YDL207w GLE1 RNA export mediator YLL008w DRS1 RNA helicase of the DEAD box family YDR194c MSS116 RNA helicase of the DEAD box family, mitochondrial YKR024c DBP7 RNA helicase required for 60S ribosomal subunit assembly YNR038w DBP6 RNA helicase required for 60S ribosomal subunit assembly YKL078w DHR2 RNA helicase, involved in ribosomal RNA maturation YER172c BRR2 RNA helicase-related protein YKL125w RRN3 RNA polymerase I specific transcription factor YBL014c RRN6 RNA polymerase I specific transcription initiation factor YLR141w RRN5 RNA polymerase I specific transcription initiation factor YML043c RRN11 RNA polymerase I specific transcription initiation factor YMR270c RRN9 RNA polymerase I specific transcription initiation factor YBL025w RRN10 RNA polymerase I-specific transcription initiation factor YHR058c MED6 RNA polymerase II transcriptional regulation mediator YDR045c RPC11 RNA polymerase III subunit C11, required for RNA cleavage activity and transcription termination YPL007c TFC8 RNA Polymerase III transcription initiation factor TFIIIC (tau), 60 kDa subunit YMR228w MTF1 RNA polymerase specific factor, mitochondrial YJL133w MRS3 RNA splicing protein and member of the mitochondrial carrier family (MCF) YKR052c MRS4 RNA splicing protein and member of the mitochondrial carrier family (MCF) YOR334w MRS2 RNA splicing protein and member of the mitochondrial carrier family (MCF) YKR086w PRP16 RNA-dependent ATPase YNR011c PRP2 RNA-dependent ATPase of DEAH box family YIR015w RPR2 RNase P subunit YPL266w DIM1 rRNA (adenine-N6,N6-)-dimethyltransferase YOR201c PET56 rRNA (guanosine-2'-O-)-methyltransferase YCR035c RRP43 rRNA processing protein YDL111c RRP42 rRNA processing protein YDR280w RRP45 rRNA processing protein YDR190c RVB1 RUVB-like protein YPL235w RVB2 RUVB-like protein YMR139w RIM11 ser/thr protein kinase YGR092w DBF2 ser/thr protein kinase related to DBF20P YAL016w TPD3 ser/thr protein phosphatase 2A, regulatory chain A YBL052c SAS3 silencing protein YOL068c HST1 silencing protein YOR025w HST3 silencing protein YDR227w SIR4 silencing regulatory and DNA-repair protein YLR442c SIR3 silencing regulatory and DNA-repair protein YKR101w SIR1 silencing regulatory protein YDL042c SIR2 silencing regulatory protein and DNA-repair protein YKL070w similarity to B.subtilis transcriptional regulatory protein YDL070w BDF2 similarity to bromodomain protein BDF1P YOR179c similarity to BRR5 protein YOL042w NGL1 similarity to CCR4 protein YIR001c SGN1 similarity to D.melanogaster RNA binding protein YGL014w similarity to Drosophila pumilio protein and MPT5P protein YBR061c similarity to E.coli ftsJ protein YGR249w MGA1 similarity to heat shock transcription factors YPL015c HST2 similarity to HST1P and SIR2P YNL107w YAF9 similarity to human AF-9 protein YPR068c HOS1 similarity to human histone deacetylase HD1 YAR044w OSH1 similarity to human oxysterol binding protein (OSBP) YAR003w FUN16 similarity to human RB protein binding protein YER169w RPH1 similarity to human retinoblastoma binding protein 2 YJR119c similarity to human retinoblastoma binding protein 2 YOL010w RCL1 similarity to human RNA 3'-terminal phosphate cyclase YPR031w similarity to human zinc-finger protein BR140 YOL133w HRT1 similarity to Lotus RING-finger protein YCL033c similarity to M.capricolum transcription repressor YER028c similarity to MIG1P YER130c similarity to MSN2P and weak similarity to MSN4P YER184c similarity to multidrug resistance proteins PDR3P and PDR1P YHR015w MIP6 similarity to PES4 a PAB-like protein Q0255 similarity to Podospora cytb intron 1a and coII intron protein 2 YPR115w similarity to probable transcription factor ASK10P, and to YNL047c and YIL105c YIL130w similarity to PUT3P and to hypothetical protein YJL206c YCR020c PET18 similarity to regulatory protein YPL230w USV1 similarity to RGM1P, weak similarity to transcription factors YIR005w IST3 similarity to RNA-binding proteins YCR087c-a similarity to S. pombe SPBC215.06c putative nucleic acid-binding protein YNL175c NOP13 similarity to S.pombe Rnp24p, NSR1P and human splicing factor YGL150c INO80 similarity to SNF2P and human SNF2alpha YCR106w similarity to transcription factor YPR008w HAA1 similarity to transcription factor YLL054c similarity to transcription factor PIP2P YPR013c similarity to transcription factors YPR015c similarity to transcription factors YDR303c RSC3 similarity to transcriptional regulator proteins YJL103c similarity to YBR239c YJL206c similarity to YIL130p and PUT3P YHR178w STB5 SIN3 binding protein YKL072w STB6 SIN3 binding protein YDR169c STB3 SIN3 protein-binding protein YMR053c STB2 SIN3P binding protein YNL309w STB1 SIN3P binding protein YHL034c SBP1 single-strand nucleic acid binding protein YBR103w SIF2 SIR4P interacting protein YBL026w LSM2 Sm-like (Lsm) protein YDR378c LSM6 Sm-like (Lsm) protein YER112w LSM4 Sm-like (Lsm) protein YER146w LSM5 Sm-like (Lsm) protein YJL124c LSM1 Sm-like (Lsm) protein YLR438c-a LSM3 Sm-like (Lsm) protein YNL147w LSM7 Sm-like (Lsm) protein YPL178w CBC2 small subunit of the nuclear cap-binding protein complex CBC YGR074w SMD1 snRNA-associated protein YPR182w SMX3 snRNA-associated protein of the SM family YFR005c SAD1 SnRNP assembly defective YFL017w-a SMX2 snRNP G protein (the homologue of the human Sm-G) YBR055c PRP6 snRNP(U4/U6)-associated splicing factor YOR159c SME1 spliceosomal snRNA-associated Sm core protein required for mRNA splicing, also likely associated with telomerase TLC1 RNA YLR147c SMD3 spliceosomal snRNA-associated Sm core protein required for pre-mRNA splicing YBR188c NTC20 splicing factor YJR022w LSM8 splicing factor YKL012w PRP40 splicing factor YPR101w SNT309 splicing factor YPR134w MSS18 splicing protein YGR222w PET54 splicing protein and translational activator, mitochondrial YLR399c BDF1 sporulation protein YNL204c SPS18 sporulation-specific zinc-finger protein YMR037c MSN2 stress responsive regulatory protein YIL101c XBP1 stress-induced transcriptional repressor YBR245c ISW1 strong similarity to D.melanogaster iswi protein YDR026c strong similarity to DNA-binding protein REB1P YOR304w ISW2 strong similarity to Drosophila ISW1 and human SNF2P homolog YLR117c CLF1 strong similarity to Drosophila putative cell cycle control protein crn YHR169w DBP8 strong similarity to DRS1P and other probable ATP-dependent RNA helicases YNL004w HRB1 strong similarity to GBP2P YBR238c strong similarity to general chromatin factor SPT16P YGL236c MTO1 strong similarity to gidA E.coli protein YFL052w strong similarity to Mal63p, YPR196w and MAL13P YPL060w LPE10 strong similarity to MRS2P YNL255c GIS2 strong similarity to nucleic acid-binding proteins, similarity to Tetrahymena thermophila cnjB protein YPR196w strong similarity to regulatory protein Mal63p YCR004c YCP4 strong similarity to S. pombe protein obr1 YGR248w SOL4 strong similarity to SOL3P YLR228c ECM22 strong similarity to YDR213w, weak similarity to LYS14P YHR056c RSC30 strong similarity to YHR054c YDR451c YHP1 strong similarity to YOX1P YML081w strong similarity to ZMS1 protein YPL086c ELP3 subunit of elongator/RNAPII holoenzyme with histone acetylase activity YER116c SLX8 subunit of HEX3P-SLX8P complex, required for cell growth in the absence of SGS1 or TOP3 YGL133w ITC1 subunit of ISW2 chromatin remodelling complex YNR010w CSE2 subunit of RNA polymerase II mediator complex YMR263w SAP30 subunit of the histone deacetylase B complex YEL056w HAT2 subunit of the major yeast histone acetyltransferase YCR052w RSC6 subunit of the RSC complex YFR037c RSC8 subunit of the RSC complex YIL126w STH1 subunit of the RSC complex YLR321c SFH1 subunit of the RSC complex YOR213c SAS5 subunit of the RSC complex YLR316c TAD3 subunit of tRNA-specific adenosine-34 deaminase YGL254w FZF1 sulfite resistance protein YLR139c SLS1 suppresses lethality of SSM4 deletion YNL222w SSU72 suppressor of cs mutant of SUA7 YML017w PSP2 suppressor of DNA polymerase alpha mutation YPR125w MRS7 suppressor of MRS2-1 mutation YKR092c SRP40 suppressor of mutant AC40 of RNA polymerase I and III YBR152w SPP381 Suppressor of Pre-mRNA Processing mutant YLR119w SRN2 suppressor of RNA1-1 mutation YDR310c SUM1 suppressor of SIR mutations YDR416w SYF1 synthetic lethal with CDC40 YGR129w SYF2 synthetic lethal with CDC40 YML114c TAF65 TBP Associated Factor 65 KDa YKL058w TOA2 TFIIA subunit (transcription initiation factor), 13.5 kD YOR194c TOA1 TFIIA subunit (transcription initiation factor), 32 kD YPR086w SUA7 TFIIB subunit (transcription initiation factor), factor E YBR198c TAF90 TFIID and SAGA subunit YDR145w TAF61 TFIID and SAGA subunit YDR167w TAF25 TFIID and SAGA subunit YGL112c TAF60 TFIID and SAGA subunit YMR236w TAF17 TFIID and SAGA subunit YGR274c TAF145 TFIID subunit (TBP-associated factor), 145 kD YML098w TAF19 TFIID subunit (TBP-associated factor), 19 kD YML015c TAF40 TFIID subunit (TBP-associated factor), 40KD YMR227c TAF67 TFIID subunit (TBP-associated factor), 67 kD YKR062w TFA2 TFIIE subunit (transcription initiation factor), 43 KD YKL028w TFA1 TFIIE subunit (transcription initiation factor), 66 kD YMR277w FCP1 TFIIF interacting component of CTD phosphatase YGR186w TFG1 TFIIF subunit (transcription initiation factor), 105 kD YPL129w ANC1 TFIIF subunit (transcription initiation factor), 30 kD YGR005c TFG2 TFIIF subunit (transcription initiation factor), 54 kD YDR311w TFB1 TFIIH subunit (transcription initiation factor), 75 kD YPR025c CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YLR005w SSL1 TFIIH subunit (transcription initiation factor), factor B YDR460w TFB3 TFIIH subunit (transcription/repair factor) YPL122c TFB2 TFIIH subunit (transcription/repair factor) YPR186c PZF1 TFIIIA (transcription initiation factor) YGR246c BRF1 TFIIIB subunit, 70 kD YNL039w TFC5 TFIIIB subunit, 90 kD YGR047c TFC4 TFIIIC (transcription initiation factor) subunit, 131 kD YAL001c TFC3 TFIIIC (transcription initiation factor) subunit, 138 kD YOR110w TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YDR362c TFC6 TFIIIC (transcription initiation factor) subunit, 91 kD YBR123c TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YGL043w DST1 TFIIS (transcription elongation factor) YER148w SPT15 the TATA-binding protein TBP YCR077c PAT1 topoisomerase II-associated protein YGR063c SPT4 transcription elongation protein YGR116w SPT6 transcription elongation protein YML010w SPT5 transcription elongation protein YBL093c ROX3 transcription factor YBR049c REB1 transcription factor YCR065w HCM1 transcription factor YDL165w CDC36 transcription factor YDR146c SWI5 transcription factor YER111c SWI4 transcription factor YFL031w HAC1 transcription factor YFR034c PHO4 transcription factor YGL013c PDR1 transcription factor YKL043w PHD1 transcription factor YKR099w BAS1 transcription factor YLR098c CHA4 transcription factor YLR182w SWI6 transcription factor YLR256w HAP1 transcription factor YLR451w LEU3 transcription factor YOR140w SFL1 transcription factor YOR162c YRR1 transcription factor YPL248c GAL4 transcription factor YFL021w GAT1 transcription factor for nitrogen regulation YER040w GLN3 transcription factor for positive nitrogen regulation YML099c ARG81 transcription factor involved in arginine metabolism YMR042w ARG80 transcription factor involved in arginine metabolism YMR280c CAT8 transcription factor involved in gluconeogenesis YGL181w GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YMR043w MCM1 transcription factor of the MADS box family YPL089c RLM1 transcription factor of the MADS box family YLR014c PPR1 transcription factor regulating pyrimidine pathway YJR094c IME1 transcription factor required for sporulation YHR206w SKN7 transcription factor with similarity to HSF1P YJR127c ZMS1 transcription factor with similarity to regulatory protein ARD1P YDR259c YAP6 transcription factor, of a fungal-specific family of bzip proteins YHL009c YAP3 transcription factor, of a fungal-specific family of bzip proteins YDL056w MBP1 transcription factor, subunit of the MBF factor YOR174w MED4 transcription regulation mediator YJL127c SPT10 transcription regulatory protein YJL176c SWI3 transcription regulatory protein YOL004w SIN3 transcription regulatory protein YPL082c MOT1 transcriptional accessory protein YDR423c CAD1 transcriptional activator YHR084w STE12 transcriptional activator YKL062w MSN4 transcriptional activator YOL116w MSN1 transcriptional activator YOR028c CIN5 transcriptional activator YPL075w GCR1 transcriptional activator YIR023w DAL81 transcriptional activator for allantoin and GABA catabolic genes YNL314w DAL82 transcriptional activator for allantoin catabolic genes YDL170w UGA3 transcriptional activator for GABA catabolic genes YML007w YAP1 transcriptional activator involved in oxidative stress response YEL009c GCN4 transcriptional activator of amino acid biosynthetic genes YOL089c HAL9 transcriptional activator of ENA1 YDR034c LYS14 transcriptional activator of lysine pathway genes YIL129c TAO3 Transcriptional Activator of OCH1 YIR017c MET28 transcriptional activator of sulfur amino acid metabolism YNL103w MET4 transcriptional activator of sulfur metabolism YPR104c FHL1 transcriptional activator of the forkhead/hnf3 family YLR055c SPT8 transcriptional adaptor or co-activator YMR039c SUB1 transcriptional coactivator YPL254w HFI1 transcriptional coactivator YOR229w WTM2 transcriptional modulator YOR230w WTM1 transcriptional modulator YBR193c MED8 transcriptional regulation mediator YDL005c MED2 transcriptional regulation mediator YAL021c CCR4 transcriptional regulator YER164w CHD1 transcriptional regulator YIL084c SDS3 transcriptional regulator YNL012w SPO1 transcriptional regulator involved in sporulation YDR160w SSY1 transcriptional regulator of several transporter genes YDR253c MET32 transcriptional regulator of sulfur amino acid metabolism YPL038w MET31 transcriptional regulator of sulfur amino acid metabolism YER068w MOT2 transcriptional repressor YGL035c MIG1 transcriptional repressor YJL110c GZF3 transcriptional repressor YKR034w DAL80 transcriptional repressor for allantoin and GABA catabolic genes YDR043c NRG1 transcriptional repressor for glucose repression of STA1 gene expression YMR182c RGM1 transcriptional repressor protein YNL062c GCD10 translation initiation factor eIF3 RNA-binding subunit YBL024w NCL1 tRNA (cytosine-5-)-methyltransferase YDL112w TRM3 tRNA (guanosine-2'-O-)-methyltransferase YOL102c TPT1 tRNA 2'-phosphotransferase YOR274w MOD5 tRNA isopentenyltransferase YJL087c TRL1 tRNA ligase YER168c CCA1 tRNA nucleotidyltransferase YPL083c SEN54 tRNA splicing endonuclease alpha subunit YLR105c SEN2 tRNA splicing endonuclease beta subunit YMR059w SEN15 tRNA splicing endonuclease delta subunit YAR008w SEN34 tRNA splicing endonuclease gamma subunit YGL243w TAD1 tRNA-specific adenosine deaminase 1 YJL035c TAD2 tRNA-specific adenosine deaminase 2 YLR136c TIS11 tRNA-specific adenosine deaminase 3 YBR083w TEC1 Ty transcription activator YOR337w TEA1 TY1 enhancer activator YIL061c SNP1 U1 small nuclear ribonucleoprotein YDR240c SNU56 U1 snRNA protein, no counterpart in mammalian snRNP YDR235w PRP42 U1 snRNP associated protein, required for pre-mRNA splicing YLR275w SMD2 U1 snRNP protein of the Sm class YBR119w MUD1 U1 snRNP-specific A protein YPL213w LEA1 U2 A' snRNP protein YIR009w MSL1 U2 snRNA-associated protein with similarity to U2B YMR240c CUS1 U2 snRNP protein YPR178w PRP4 U4/U6 snRNP 52 KD protein YGR006w PRP18 U5 snRNA-associated protein YHR165c PRP8 U5 snRNP protein, pre-mRNA splicing factor YGL141w HUL5 ubiquitin-protein ligase (E3) YER151c UBP3 ubiquitin-specific proteinase YNR063w weak similarity to CYC1/CYP3 transcription activator YLR013w GAT3 weak similarity to nitrogen regulatory proteins YIL105c weak similarity to probable transcription factor ASK10P YGR200c ELP2 weak similarity to rape guanine nucleotide regulatory protein YLR278c weak similarity to regulatory proteins YML076c weak similarity to transcription factor YBR239c weak similarity to transcription factor PUT3P YBR033w weak similarity to transcription factors YBR150c TBS1 weak similarity to transcription factors YGR067c weak similarity to transcription factors YKR064w weak similarity to transcription factors YLR266c weak similarity to transcription factors YPL133c weak similarity to transcription factors YKL222c weak similarity to transcription factors, similarity to finger proteins YOR162c, YOR172w and YLR266c YBL054w weak similarity to transforming protein (B-myb) YMR019w STB4 weak similarity to YIL130w, PUT3P and other transcription factors YKL005c weak similarity to YKR029c and D.melanogaster transcription elongation factor DmS-II YDL087c LUC7 yeast U1 snRNP protein with a role in 5' splice site recognition YER122c GLO3 zinc finger protein YDR216w ADR1 zinc-finger transcription factor YGR044c RME1 zinc-finger transcription factor Back to MIPS Yeast Functional Categories Page. 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