transcriptional control (333 ORFs)YOR259c RPT4 26S proteasome regulatory subunit YHR193c EGD2 alpha subunit of the nascent polypeptide-associated complex YDR252w BTT1 alternate beta subunit of the nascent polypeptide-associated complex YDL197c ASF2 anti-silencing protein YJL115w ASF1 anti-silencing protein YDR173c ARG82 arginine metabolism transcription factor YKL112w ABF1 ARS-binding factor YFL028c CAF16 ATP-binding cassette transporter family member YDR123c INO2 basic helix-loop-helix (BHLH) transcription factor YOL108c INO4 basic helix-loop-helix transcription factor YOR344c TYE7 basic helix-loop-helix transcription factor YOL067c RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YBL103c RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YGL209w MIG2 C2H2 zinc-finger protein YLR433c CNA1 calcineurin B, catalytic subunit YML057w CMP2 calcineurin B, catalytic subunit YKL190w CNB1 calcineurin B, regulatory subunit YNL027w CRZ1 calcineurin responsive zinc-finger YIL033c BCY1 cAMP dependent protein kinase, regulatory subunit YJL164c TPK1 cAMP-dependent protein kinase 1, catalytic chain YPL203w TPK2 cAMP-dependent protein kinase 2, catalytic chain YKL166c TPK3 cAMP-dependent protein kinase 3, catalytic chain YKL139w CTK1 carboxy-terminal domain (CTD) kinase, alpha subunit YJL006c CTK2 carboxy-terminal domain (CTD) kinase, beta subunit YML112w CTK3 carboxy-terminal domain (CTD) kinase, gamma subunit YBL021c HAP3 CCAAT-binding factor subunit YGL237c HAP2 CCAAT-binding factor subunit YKL109w HAP4 CCAAT-binding factor subunit YOR358w HAP5 CCAAT-binding factor subunit YJR122w CAF17 CCR4 associated factor YKR036c CAF4 CCR4 associated factor YBR215w HPC2 cell cycle regulatory protein YDL220c CDC13 cell division control protein YMR061w RNA14 component of pre-mRNA 3'-end processing factor CF I YNR023w SNF12 component of SWI/SNF global transcription activator complex YOR290c SNF2 component of SWI/SNF global transcription activator complex YPL016w SWI1 component of SWI/SNF global transcription activator complex YBR289w SNF5 component of SWI/SNF transcription activator complex YDR073w SNF11 component of SWI/SNF transcription activator complex YCR042c TSM1 component of TFIID complex YHR099w TRA1 component of the Ada-Spt transcriptional regulatory complex YPR072w NOT5 component of the NOT protein complex YLR192c HCR1 component of translation initiation factor eIF3, has similarity to human eIF3 p35 subunit YGL166w CUP2 copper-dependent transcription factor YNL167c SKO1 cre-binding bzip protein YOL001w PHO80 cyclin YPL042c SSN3 cyclin-dependent CTD kinase YPL031c PHO85 cyclin-dependent protein kinase YDR334w SWR1 DEAH-box protein, putative RNA helicase YNL186w UBP10 derepression of telomeric silencing YLR226w BUR2 divergent CDK-cyclin complex YDR217c RAD9 DNA repair checkpoint protein YNL216w RAP1 DNA-binding protein with repressor and activator activity YLR418c CDC73 DNA-directed RNA polymerase II accessory protein YBR279w PAF1 DNA-directed RNA polymerase II regulator YGL208w SIP2 dominant suppressor of some ts mutations in RPO21 and PRP4 YOR047c STD1 dosage-dependent modulator of glucose repression YHR154w ESC4 Establishes Silent Chromatin YIL131c FKH1 forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle YER159c BUR6 functional homolog of human NC2alpha YDR397c NCB2 functional homolog of human NC2beta/Dr1 YPL037c EGD1 GAL4 DNA-binding enhancer protein YBR020w GAL1 galactokinase YDR009w GAL3 galactokinase YIL038c NOT3 general negative regulator of transcription, subunit 3 YBR112c CYC8 general repressor of transcription YCR084c TUP1 general transcription repressor YDR176w NGG1 general transcriptional adaptor or co-activator YDR392w SPT3 general transcriptional adaptor or co-activator YDR448w ADA2 general transcriptional adaptor or co-activator YBR045c GIP1 GLC7-interacting protein YNL236w SIN4 global regulator protein YHL025w SNF6 global transcription activator YER027c GAL83 glucose repression protein YNL199c GCR2 glycolytic genes transcriptional activator YGL073w HSF1 heat shock transcription factor YPR065w ROX1 heme-dependent transcriptional repressor of hypoxic genes YDR006c SOK1 high copy suppressor of a cyclic AMP-dependent protein kinase mutant YJR147w HMS2 High-copy MEP2 Suppressor YMR070w MOT3 high-copy suppressor of MOT1-SPT3 synthetic lethality YGR252w GCN5 histone acetyltransferase YNL021w HDA1 histone deacetylase A YNL330c RPD3 histone deacetylase B YDR225w HTA1 histone H2A YBL003c HTA2 histone H2A.2 YDR224c HTB1 histone H2B YBL002w HTB2 histone H2B.2 YBR010w HHT1 histone H3 YNL031c HHT2 histone H3 YBR009c HHF1 histone H4 YNL030w HHF2 histone H4 YBL008w HIR1 histone transcription regulator YOR038c HIR2 histone transcription regulator YDL106c PHO2 homeodomain protein YOL055c THI20 hydroxymethylpyrimidine phosphate (HMP-P) kinase YDR138w HPR1 hyperrecombination protein related to TOP1P YKL159c RCN1 inhibitor of calcineurin YJL089w SIP4 interacts with SNF1 protein kinase YKL032c IXR1 intrastrand crosslink recognition protein and transcription factor YBR081c SPT7 involved in alteration of transcription start site selection YJR140c HIR3 involved in cell cycle regulation of histone transcription YKR072c SIS2 involved in cell cycle-specific gene expression YPL177c CUP9 involved in copper homeostasis repression of protein import YER088c DOT6 involved in derepression of telomeric silencing YIL010w DOT5 involved in derepression of telomeric silencing YIL128w MET18 involved in NER repair and RNA polymerase II transcription YDR439w LRS4 involved in rDNA silencing YNL251c NRD1 involved in regulation of nuclear pre-mRNA abundance YIL046w MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YDL153c SAS10 involved in silencing YDR363w ESC2 involved in silencing YMR127c SAS2 involved in silencing at HMR YGR097w ASK10 involved in SKN7P-dependent transcription YIR018w YAP5 involved in transcription activation YOL028c YAP7 involved in transcription activation YLR039c RIC1 involved in transcription of ribosomal proteins and ribosomal RNA YNL097c PHO23 involved in transcriptional regulation of PHO5 YGL071w RCS1 iron-regulated transcriptional repressor YJR060w CBF1 kinetochore protein YDR159w SAC3 leucine permease transcriptional regulator YGR100w MDR1 MAC1P interacting protein YBR182c SMP1 MADS-box transcription factor YBR297w MAL33 maltose fermentation regulatory protein YGR288w MAL13 maltose pathway regulatory protein YCR039c MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040w MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCL066w HMLALPHA1 mating type regulatory protein, silenced copy at HML YGL025c PGD1 mediator complex subunit YHL027w RIM101 meiotic regulatory protein YOL135c MED7 member of RNA Polymerase II transcriptional regulation mediator complex YJR032w CPR7 member of the cyclophilin family YLR216c CPR6 member of the cyclophilin family YHR211w FLO5 member of the FLO1P family of flocculation proteins YDR191w HST4 member of the SIR2P family of putative NAD-dependent histone deacetylases YOL148c SPT20 member of the TBP class of SPT proteins that alter transcription site selection YMR021c MAC1 metal binding activator YJL056c ZAP1 metalloregulatory protein involved in zinc-responsive transcriptional regulation YLR131c ACE2 metallothionein expression activator YBR026c (MRF1) mitochondrial respiratory function protein YER161c SPT2 multifunctional HMG-like chromatin protein YOR298c-a MBF1 multiprotein bridging factor mediates GCN4-dependent transcriptional activation YML051w GAL80 negative regulator for expression of galactose-induced genes YKL185w ASH1 negative regulator of HO transcription YPL139c UME1 negative regulator of meiosis YHL020c OPI1 negative regulator of phospholipid biosynthesis pathway YDR464w SPP41 negative regulator of PRP3 and PRP4 gene expression YGL151w NUT1 negative transcription regulator from artifical reporters YPR168w NUT2 negative transcription regulator from artifical reporters YDR207c UME6 negative transcriptional regulator YGL221c NIF3 NGG1P-interacting factor 3 YCR093w CDC39 nuclear protein YGL115w SNF4 nuclear regulatory protein YML065w ORC1 origin recognition complex, 104 KD subunit YHR118c ORC6 origin recognition complex, 50 KD subunit YNL261w ORC5 origin recognition complex, 50 kDa subunit YPR162c ORC4 origin recognition complex, 56 KD subunit YLL004w ORC3 origin recognition complex, 62 kDa subunit YBR060c ORC2 origin recognition complex, 72 kDa subunit YAL051w OAF1 peroxisome proliferating transcription factor YOR363c PIP2 peroxisome proliferating transcription factor YBL005w PDR3 pleiotropic drug resistance regulatory protein YNL076w MKS1 pleiotropic regulatory factor YKL015w PUT3 positive activator of the proline utilisation pathway YDL080c THI3 positive regulation factor of thiamin metabolism YGL192w IME4 positive transcription factor for IME2 YDR421w ARO80 positive transcription regulator of ARO9 and ARO10 YDR017c KCS1 potential transcription factor of the BZIP type YDR463w STP1 pre-tRNA splicing protein, transcription factor YBL066c SEF1 putative transcription factor YBR275c RIF1 RAP1-interacting factor 1 YFR029w PTR3 regulator of expression of the PTR2, GAP1 and BAP2 genes YKL038w RGT1 regulator of glucose-induced genes YBR240c THI2 regulator of the thiamine biosynthetic genes YDR257c RMS1 regulatory protein YMR016c SOK2 regulatory protein in the PKA signal transduction pathway YDR213w UPC2 regulatory protein involved in control of sterol uptake YCL055w KAR4 regulatory protein required for pheromone induction of karyogamy genes YLR176c RFX1 repressor of DNA damage-inducible genes YIL106w MOB1 required for completion of mitosis and maintenance of ploidy YER109c FLO8 required for diploid filamentous growth YNR052c POP2 required for glucose derepression YER120w SCS2 required for inositol metabolism YMR179w SPT21 required for normal transcription at a number of loci YKL093w MBR1 required for optimal growth on glycerol YCL054w SPB1 required for ribosome synthesis, putative methylase YHR058c MED6 RNA polymerase II transcriptional regulation mediator YMR139w RIM11 ser/thr protein kinase YGR092w DBF2 ser/thr protein kinase related to DBF20P YBL052c SAS3 silencing protein YOL068c HST1 silencing protein YOR025w HST3 silencing protein YDR227w SIR4 silencing regulatory and DNA-repair protein YLR442c SIR3 silencing regulatory and DNA-repair protein YKR101w SIR1 silencing regulatory protein YDL042c SIR2 silencing regulatory protein and DNA-repair protein YKL070w similarity to B.subtilis transcriptional regulatory protein YDL070w BDF2 similarity to bromodomain protein BDF1P YBR061c similarity to E.coli ftsJ protein YGR249w MGA1 similarity to heat shock transcription factors YPL015c HST2 similarity to HST1P and SIR2P YNL107w YAF9 similarity to human AF-9 protein YAR003w FUN16 similarity to human RB protein binding protein YER169w RPH1 similarity to human retinoblastoma binding protein 2 YJR119c similarity to human retinoblastoma binding protein 2 YOL133w HRT1 similarity to Lotus RING-finger protein YER130c similarity to MSN2P and weak similarity to MSN4P YER184c similarity to multidrug resistance proteins PDR3P and PDR1P YPR115w similarity to probable transcription factor ASK10P, and to YNL047c and YIL105c YIL130w similarity to PUT3P and to hypothetical protein YJL206c YCR020c PET18 similarity to regulatory protein YGL150c INO80 similarity to SNF2P and human SNF2alpha YCR106w similarity to transcription factor YLL054c similarity to transcription factor PIP2P YDR303c RSC3 similarity to transcriptional regulator proteins YJL103c similarity to YBR239c YJL206c similarity to YIL130p and PUT3P YHR178w STB5 SIN3 binding protein YKL072w STB6 SIN3 binding protein YDR169c STB3 SIN3 protein-binding protein YMR053c STB2 SIN3P binding protein YNL309w STB1 SIN3P binding protein YBR103w SIF2 SIR4P interacting protein YLR399c BDF1 sporulation protein YNL204c SPS18 sporulation-specific zinc-finger protein YMR037c MSN2 stress responsive regulatory protein YIL101c XBP1 stress-induced transcriptional repressor YBR245c ISW1 strong similarity to D.melanogaster iswi protein YDR026c strong similarity to DNA-binding protein REB1P YOR304w ISW2 strong similarity to Drosophila ISW1 and human SNF2P homolog YGL236c MTO1 strong similarity to gidA E.coli protein YFL052w strong similarity to Mal63p, YPR196w and MAL13P YPR196w strong similarity to regulatory protein Mal63p YLR228c ECM22 strong similarity to YDR213w, weak similarity to LYS14P YHR056c RSC30 strong similarity to YHR054c YML081w strong similarity to ZMS1 protein YGL133w ITC1 subunit of ISW2 chromatin remodelling complex YMR263w SAP30 subunit of the histone deacetylase B complex YEL056w HAT2 subunit of the major yeast histone acetyltransferase YCR052w RSC6 subunit of the RSC complex YFR037c RSC8 subunit of the RSC complex YIL126w STH1 subunit of the RSC complex YLR321c SFH1 subunit of the RSC complex YOR213c SAS5 subunit of the RSC complex YGL254w FZF1 sulfite resistance protein YNL222w SSU72 suppressor of cs mutant of SUA7 YDR310c SUM1 suppressor of SIR mutations YBR198c TAF90 TFIID and SAGA subunit YDR145w TAF61 TFIID and SAGA subunit YDR167w TAF25 TFIID and SAGA subunit YGL112c TAF60 TFIID and SAGA subunit YBL093c ROX3 transcription factor YBR049c REB1 transcription factor YCR065w HCM1 transcription factor YDL165w CDC36 transcription factor YDR146c SWI5 transcription factor YER111c SWI4 transcription factor YFL031w HAC1 transcription factor YFR034c PHO4 transcription factor YGL013c PDR1 transcription factor YKL043w PHD1 transcription factor YKR099w BAS1 transcription factor YLR098c CHA4 transcription factor YLR182w SWI6 transcription factor YLR256w HAP1 transcription factor YLR451w LEU3 transcription factor YOR140w SFL1 transcription factor YPL248c GAL4 transcription factor YFL021w GAT1 transcription factor for nitrogen regulation YER040w GLN3 transcription factor for positive nitrogen regulation YML099c ARG81 transcription factor involved in arginine metabolism YMR042w ARG80 transcription factor involved in arginine metabolism YMR280c CAT8 transcription factor involved in gluconeogenesis YGL181w GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YMR043w MCM1 transcription factor of the MADS box family YPL089c RLM1 transcription factor of the MADS box family YLR014c PPR1 transcription factor regulating pyrimidine pathway YJR094c IME1 transcription factor required for sporulation YHR206w SKN7 transcription factor with similarity to HSF1P YDR259c YAP6 transcription factor, of a fungal-specific family of bzip proteins YHL009c YAP3 transcription factor, of a fungal-specific family of bzip proteins YDL056w MBP1 transcription factor, subunit of the MBF factor YJL127c SPT10 transcription regulatory protein YJL176c SWI3 transcription regulatory protein YOL004w SIN3 transcription regulatory protein YPL082c MOT1 transcriptional accessory protein YDR423c CAD1 transcriptional activator YHR084w STE12 transcriptional activator YKL062w MSN4 transcriptional activator YOL116w MSN1 transcriptional activator YOR028c CIN5 transcriptional activator YPL075w GCR1 transcriptional activator YIR023w DAL81 transcriptional activator for allantoin and GABA catabolic genes YNL314w DAL82 transcriptional activator for allantoin catabolic genes YDL170w UGA3 transcriptional activator for GABA catabolic genes YML007w YAP1 transcriptional activator involved in oxidative stress response YEL009c GCN4 transcriptional activator of amino acid biosynthetic genes YOL089c HAL9 transcriptional activator of ENA1 YDR034c LYS14 transcriptional activator of lysine pathway genes YIL129c TAO3 Transcriptional Activator of OCH1 YIR017c MET28 transcriptional activator of sulfur amino acid metabolism YNL103w MET4 transcriptional activator of sulfur metabolism YPR104c FHL1 transcriptional activator of the forkhead/hnf3 family YLR055c SPT8 transcriptional adaptor or co-activator YMR039c SUB1 transcriptional coactivator YPL254w HFI1 transcriptional coactivator YAL021c CCR4 transcriptional regulator YER164w CHD1 transcriptional regulator YIL084c SDS3 transcriptional regulator YNL012w SPO1 transcriptional regulator involved in sporulation YDR160w SSY1 transcriptional regulator of several transporter genes YDR253c MET32 transcriptional regulator of sulfur amino acid metabolism YPL038w MET31 transcriptional regulator of sulfur amino acid metabolism YER068w MOT2 transcriptional repressor YGL035c MIG1 transcriptional repressor YJL110c GZF3 transcriptional repressor YKR034w DAL80 transcriptional repressor for allantoin and GABA catabolic genes YDR043c NRG1 transcriptional repressor for glucose repression of STA1 gene expression YMR182c RGM1 transcriptional repressor protein YBR083w TEC1 Ty transcription activator YOR337w TEA1 TY1 enhancer activator YER151c UBP3 ubiquitin-specific proteinase YLR013w GAT3 weak similarity to nitrogen regulatory proteins YLR278c weak similarity to regulatory proteins YML076c weak similarity to transcription factor YBR033w weak similarity to transcription factors YKR064w weak similarity to transcription factors YLR266c weak similarity to transcription factors YKL222c weak similarity to transcription factors, similarity to finger proteins YOR162c, YOR172w and YLR266c YBL054w weak similarity to transforming protein (B-myb) YMR019w STB4 weak similarity to YIL130w, PUT3P and other transcription factors YER122c GLO3 zinc finger protein YDR216w ADR1 zinc-finger transcription factor YGR044c RME1 zinc-finger transcription factor Back to MIPS Yeast Functional Categories Page. Back to MIPS Genome Project Page. Back to MIPS Homepage. mail questions/comments to webmaster
|