Saccharomyces cerevisiae -
Functional Catalogue

mips


 

proteolysis (159 ORFs)

YOL038w     PRE6     20S proteasome subunit (alpha4)
YJL001w     PRE3     20S proteasome subunit (beta1)
YOR157c     PUP1     20S proteasome subunit (beta2)
YER094c     PUP3     20S proteasome subunit (beta3)
YPR103w     PRE2     20S proteasome subunit (beta5)
YOR362c     PRE10    20S proteasome subunit C1 (alpha7)
YER012w     PRE1     20S proteasome subunit C11(beta4)
YGR135w     PRE9     20S proteasome subunit Y13 (alpha3)
YML092c     PRE8     20S proteasome subunit Y7 (alpha2)
YGL011c     SCL1     20S proteasome subunit YC7ALPHA/Y8 (alpha1)
YGR253c     PUP2     20S proteasome subunit(alpha5)
YMR314w     PRE5     20S proteasome subunit(alpha6)
YBL041w     PRE7     20S proteasome subunit(beta6)
YFR050c     PRE4     20S proteasome subunit(beta7)
YDL007w     RPT2     26S proteasome regulatory subunit
YDR394w     RPT3     26S proteasome regulatory subunit
YER021w     RPN3     26S proteasome regulatory subunit
YFR004w     RPN11    26S proteasome regulatory subunit
YFR052w     RPN12    26S proteasome regulatory subunit
YGL048c     RPT6     26S proteasome regulatory subunit
YHR027c     RPN1     26S proteasome regulatory subunit
YHR200w     RPN10    26S proteasome regulatory subunit
YIL075c     RPN2     26S proteasome regulatory subunit
YKL145w     RPT1     26S proteasome regulatory subunit
YOR117w     RPT5     26S proteasome regulatory subunit
YOR259c     RPT4     26S proteasome regulatory subunit
YOR261c     RPN8     26S proteasome regulatory subunit
YDL020c     RPN4     26S proteasome subunit
YGR270w     YTA7     26S proteasome subunit
YJR062c     NTA1     amino-terminal amidase
YKL103c     LAP4     aminopeptidase yscI precursor, vacuolar
YGL017w     ATE1     arginyl tRNA transferase
YPL154c     PEP4     aspartyl protease
YDR144c     MKC7     aspartyl protease of the periplasmic space
YBL022c     PIM1     ATP-dependent protease, mitochondrial
YIL015w     BAR1     barrierpepsin precursor
YMR297w     PRC1     carboxypeptidase y, serine-type protease
YGL116w     CDC20    cell division control protein
YMR159c     APG16    coiled-coil protein required for autophagy
YGL240w     DOC1     component of the anaphase promoting complex
YLR127c     APC2     component of the anaphase promoting complex
YOR249c     APC5     component of the anaphase-promoting complex
YBR217w     APG12    component of the autophagic system
YDL132w     CDC53    controls G1/S transition
YHR028c     DAP2     dipeptidyl aminopeptidase B
YDR390c     UBA2     E1-like (ubiquitin-activating) enzyme
YKL210w     UBA1     E1-like (ubiquitin-activating) enzyme
YBR082c     UBC4     E2 ubiquitin-conjugating enzyme
YDL064w     UBC9     E2 ubiquitin-conjugating enzyme
YDR054c     CDC34    E2 ubiquitin-conjugating enzyme
YDR059c     UBC5     E2 ubiquitin-conjugating enzyme
YDR092w     UBC13    E2 ubiquitin-conjugating enzyme
YDR177w     UBC1     E2 ubiquitin-conjugating enzyme
YER100w     UBC6     E2 ubiquitin-conjugating enzyme
YGL058w     RAD6     E2 ubiquitin-conjugating enzyme
YMR022w     QRI8     E2 ubiquitin-conjugation enzyme
YGL180w     APG1     essential for autophagocytosis
YNR007c     AUT1     essential for autophagocytosis
YBL078c     AUT7     essential for autophagy
YNL223w     AUT2     essential for autophagy
YOR123c     LEO1     extremely hydrophilic protein
YPR180w     AOS1     forms together with UBA2P a heterodimeric activating enzyme for SMT3P
YJL172w     CPS1     Gly-X carboxypeptidase YSCS precursor
YLR121c     YPS3     GPI-anchored aspartyl protease 3 (yapsin 3)
YER125w     RSP5     hect domain E3 ubiquitin-protein ligase
YDL053c              hypothetical protein
YPL149w     APG5     involved in autophagy and nutrient starvation
YLR207w     HRD3     involved in degradation of HMG2P
YOL013c     HRD1     involved in degradation of HMG2P
YML088w     UFO1     involved in degradation of HO protein
YBR201w     DER1     involved in degradation proteins in the ER
YLR452c     SST2     involved in desensitization to alpha-factor pheromone
YIL046w     MET30    involved in regulation of sulfur assimilation genes and cell cycle progression
YKL213c     DOA1     involved in ubiquitin-dependent proteolysis
YMR264w     CUE1     involved in ubiquitination and degradation at the ER surface
YPL120w     VPS30    involved in vacuolare protein sorting and autophagy
YDR328c     SKP1     kinetochore protein complex CBF3, subunit D
YER047c     SAP1     member of the AAA-protein family
YNL239w     LAP3     member of the GAL regulon
YDL126c     CDC48    microsomal protein of CDC48/PAS1/SEC18 family of ATPases
YBR165w     UBS1     positive regulator of CDC34P
YGR232w     NAS6     possible homolog of human 26S proteasome regulatory subunit p28
YMR174c     PAI3     protease A (ysca) inhibitor IA3
YEL060c     PRB1     protease B, vacuolar
YER017c     AFG3     protease of the SEC18/CDC48/PAS1 family of ATPases (AAA)
YMR089c     YTA12    protease of the SEC18/CDC48/PAS1 family of ATPases (AAA)
YPR024w     YME1     protease of the SEC18/CDC48/PAS1 family of ATPases (AAA)
YBR173c     UMP1     proteasome maturation factor
YLR423c     APG17    protein involved in authophagy
YPR185w     APG13    protein required for the autophagic process
YPL096w     PNG1     protein with de-N-glycosylation function
YNL015w     PBI2     proteinase B inhibitor 2
YCL057w     PRD1     proteinase yscD
YBR128c     APG14    required for autophagy
YBR105c     VID24    required for vacuolar import and degradation of FBP1P
YCL008c     STP22    required for vacuolar targeting of temperature-sensitive plasma membrane proteins, STE2P and CAN1P
YNR069c              similarity to central part of BUL1P
YBR227c     MCX1     similarity to E.coli ATP-binding protein clpX
YER078c              similarity to E.coli X-Pro aminopeptidase II
YMR304w     UBP15    similarity to human ubiquitin-specific protease
YDR330w              similarity to hypothetical S. pombe protein
YIL137c              similarity to M.musculus aminopeptidase
YMR223w     UBP8     similarity to mouse deubiquitinating enzyme and UBP13P,UBP9,DOA4P
YKR038c              similarity to QRI7P
YKL010c     UFD4     similarity to rat ubiquitin ligase Nedd4
YCR045c              similarity to serin proteases
YHR113w              similarity to vacuolar aminopeptidase Ape1p
YPL074w     YTA6     similarity to VPS4P and YER047c
YFR006w              similarity to X-Pro dipeptidases
YLR387c              similarity to YBR267w
YIL031w     ULP2     SMT3P-specific protease, degrades conjugated ubiquitin-like protein SMT3P
YBR139w              strong similarity to carboxypeptidase
YOL153c              strong similarity to CPS1P
YOR339c     UBC11    strong similarity to E2 ubiquitin-conjugating enzymes
YBR214w     SDS24    strong similarity to hypothetical protein YGL056c
YML111w     BUL2     strong similarity to ubiquitination protein BUL1P
YGL003c     CDH1     substrate-specific activator of APC-dependent proteolysis
YOR003w     YSP3     subtilisin-like protease III
YBL084c     CDC27    subunit of anaphase-promoting complex (cyclosome)
YFR036w     CDC26    subunit of anaphase-promoting complex (cyclosome)
YHR166c     CDC23    subunit of anaphase-promoting complex (cyclosome)
YKL022c     CDC16    subunit of anaphase-promoting complex (cyclosome)
YNL172w     APC1     subunit of anaphase-promoting complex (cyclosome)
YDL008w     APC11    subunit of the anaphase promoting complex
YDR118w     APC4     subunit of the anaphase promoting complex
YLR102c     APC9     subunit of the Anaphase Promoting Complex
YDL097c     RPN6     subunit of the regulatory particle of the proteasome
YDL147w     RPN5     subunit of the regulatory particle of the proteasome
YDR427w     RPN9     subunit of the regulatory particle of the proteasome
YPR108w     RPN7     subunit of the regulatory particle of the proteasome
YOR057w     SGT1     suppressor of G2 allele of SKP1
YIL148w     RPL40A   ubiquitin
YKR094c     RPL40B   ubiquitin
YLL039c     UBI4     ubiquitin
YJL197w     UBP12    ubiquitin C-terminal hydrolase
YKR098c     UBP11    ubiquitin C-terminal hydrolase
YIL156w     UBP7     ubiquitin carboxy terminal hydrolase
YBL067c     UBP13    ubiquitin carboxyl-terminal hydrolase
YER098w     UBP9     ubiquitin carboxyl-terminal hydrolase
YDL190c     UFD2     ubiquitin fusion degradation protein
YGR048w     UFD1     ubiquitin fusion degradation protein
YBR058c     UBP14    ubiquitin specific protease
YGR184c     UBR1     ubiquitin-protein ligase
YDL122w     UBP1     ubiquitin-specific protease
YDR069c     DOA4     ubiquitin-specific protease
YER144c     UBP5     ubiquitin-specific protease
YFR010w     UBP6     ubiquitin-specific protease
YJR099w     YUH1     ubiquitin-specific protease
YER151c     UBP3     ubiquitin-specific proteinase
YOR124c     UBP2     ubiquitin-specific proteinase
YLR167w     RPS31    ubiquitin/40S small subunit ribosomal protein
YMR275c     BUL1     ubiquitination pathway protein
YPL020c     ULP1     Ubl-specific protease
YBR286w     APE3     vacuolar aminopeptidase Y
YDL077c     VAM6     vacuolar carboxypeptidase Y
YGL227w     VID30    weak similarity to human RANBPM NP_005484.1
YOL111c              weak similarity to human ubiquitin-like protein GDX
YJL036w     SNX4     weak similarity to MVP1P
YPL072w     UBP16    weak similarity to UBP11P

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