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Saccharomyces cerevisiae - Functional Catalogue |
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intracellular communication (133 ORFs)
YPL268w PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YER177w BMH1 14-3-3 protein involved in rapamycin-sensitive signalling YJL005w CYR1 adenylate cyclase YNL138w SRV2 adenylate cyclase-associated protein, 70kDa YDR264c AKR1 ankyrin repeat-containing protein YBR200w BEM1 bud emergence mediator YPL161c BEM4 bud emergence protein YFR014c CMK1 Ca2+/calmodulin-dependent ser/thr protein kinase type I YOL016c CMK2 Ca2+/calmodulin-dependent ser/thr protein kinase, type II YBR109c CMD1 calmodulin YJL164c TPK1 cAMP-dependent protein kinase 1, catalytic chain YPL203w TPK2 cAMP-dependent protein kinase 2, catalytic chain YKL166c TPK3 cAMP-dependent protein kinase 3, catalytic chain YLR178c TFS1 CDC25-dependent nutrient- and ammonia-response cell-cycle regulator YDR309c GIC2 CDC42 GTPase-binding protein YHR061c GIC1 CDC42 GTPase-binding protein YCL027w FUS1 cell fusion protein YBR195c MSI1 chromatin assembly complex, subunit p50 YMR028w TAP42 component of the Tor signaling pathway YJL157c FAR1 cyclin-dependent kinase inhibitor (CKI) YNL053w MSG5 dual-specifity protein phosphatase YDL212w SHR3 endoplasmatic reticulum membrane protein YDL035c GPR1 G-protein coupled receptor YLL016w SDC25 GDP/GTP exchange factor (GEF) YLR310c CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR371w ROM2 GDP/GTP exchange factor for RHO1P YGR070w ROM1 GDP/GTP exchange protein for RHO1P YDL022w GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YNL098c RAS2 GTP-binding protein YOR101w RAS1 GTP-binding protein YHR005c GPA1 GTP-binding protein alpha subunit of the pheromone pathway YOR212w STE4 GTP-binding protein beta subunit of the pheromone pathway YJR086w STE18 GTP-binding protein gamma subunit of the pheromone pathway YLR229c CDC42 GTP-binding protein of RAS superfamily YNL173c MDG1 GTP-binding protein of the pheromone-response pathway YML064c TEM1 GTP-binding protein of the RAS superfamily YNL090w RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YPR165w RHO1 GTP-binding protein of the rho subfamily of ras-like proteins YAL041w CDC24 GTP/GDP exchange factor for CDC42P YPL115c BEM3 GTPase-activating protein for CDC42P and RHO1P YER020w GPA2 guanine nucleotide-binding regulatory protein YFL014w HSP12 heat shock protein YPL106c SSE1 heat shock protein of HSP70 family YDL194w SNF3 high-affinity glucose transporter/regulatory protein YJL146w IDS2 IME2-dependent signaling protein YBR140c IRA1 inhibitory regulator protein of the ras-cyclic AMP pathway YDR315c IPK1 inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IP5 2-kinase) YGR238c KEL2 involved in cell fusion and morphogenesis YHR158c KEL1 involved in cell fusion and morphology YLL021w SPA2 involved in cell polarity YLR452c SST2 involved in desensitization to alpha-factor pheromone YLR336c SGD1 involved in HOG pathway YMR052w FAR3 involved in pheromone-mediated cell cycle arrest YJR059w PTK2 involved in polyamine uptake YER118c SHO1 involved in the HOG1 high-osmolarity signal transduction pathway YCR073c SSK22 MAP kinase kinase kinase YNR031c SSK2 MAP kinase kinase kinase of the high osmolarity signal transduction pathway YDR461w MFA1 mating pheromone a-factor 1 YIL047c SYG1 member of the major facilitator superfamily YBL016w FUS3 mitogen-activated protein kinase (MAP kinase) YGL178w MPT5 multicopy suppressor of POP2 YER072w VTC1 Negative Regulator of Cdc Fourty two (CDC42) YOR107w RGS2 negative regulator of glucose-induced cAMP signaling pathway YKL185w ASH1 negative regulator of HO transcription YIL119c RPI1 negative regulator of ras-cAMP pathway YJL156c SSY5 part of an extracellular amino acid sensor YKL178c STE3 pheromone a-factor receptor YFL026w STE2 pheromone alpha-factor receptor YBR129c OPY1 pheromone resistant yeast 1 YCL032w STE50 pheromone response pathway protein YDR103w STE5 pheromone signal transduction pathway protein YDR183w PLP1 Phosducin homologue likely to be involved in regulation of pheromone response YJR066w TOR1 phosphatidylinositol 3-kinase YKL203c TOR2 phosphatidylinositol 3-kinase YLR240w VPS34 phosphatidylinositol 3-kinase YNL267w PIK1 phosphatidylinositol 4-kinase YIL002c INP51 phosphatidylinositol phosphate 5-phosphatase YLR305c STT4 phosphatidylinositol-4-kinase YDR208w MSS4 phosphatidylinositol-4-phosphate 5-kinase YDL235c YPD1 phosphorelay intermediate between SLN1P and SSK1P YKL198c PTK1 polyamine transport enhancing protein YDL090c RAM1 protein farnesyltransferase, beta subunit YDL101c DUN1 protein kinase YHR079c IRE1 protein kinase YOR149c SMP3 protein kinase C pathway protein YPL140c MKK2 protein kinase of the map kinase kinase (MEK) family YDL006w PTC1 protein serine/threonine phosphatase 2c YIR026c YVH1 protein tyrosine phosphatase YOR208w PTP2 protein-tyrosine-phosphatase YOL110w SHR5 RAS suppressor YDR373w FRQ1 regulator of phosphatidylinositol-4-OH kinase protein YMR016c SOK2 regulatory protein in the PKA signal transduction pathway YGR216c GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YPL084w BRO1 required for normal response to nutrient limitation YCR027c RSG1 rheb-like Gene involved in growth regulation YDL135c RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YBL105c PKC1 ser/thr protein kinase YOR231w MKK1 ser/thr protein kinase YLR113w HOG1 ser/thr protein kinase of MAP kinase (MAPK) family YHR030c SLT2 ser/thr protein kinase of MAP kinase family YGR040w KSS1 ser/thr protein kinase of the MAP kinase family YJL095w BCK1 ser/thr protein kinase of the MEKK family YLR362w STE11 ser/thr protein kinase of the MEKK family YHL007c STE20 ser/thr protein kinase of the pheromone pathway YPL153c RAD53 ser/thr/tyr protein kinase YDL159w STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YHR205w SCH9 serine/threonine protein kinase involved in stress response and nutrient-sensing signaling pathway YNL132w KRE33 similarity to A.ambisexualis antheridiol steroid receptor YBR260c RGD1 similarity to C.elegans GTPase-activating protein YDR379w RGA2 similarity to Dbm1p and to the rat GAP-associated protein p190 YDR287w similarity to inositolmonophosphatases YHR046c similarity to inositolmonophosphatases YHR146w CRP1 similarity to pheromone-response G-protein MDG1P YLR150w STM1 specific affinity for guanine-rich quadruplex nucleic acids YPR054w SMK1 sporulation-specific MAP kinase YOL113w SKM1 STE20/PAK-like protein kinase YKL161c (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YDR099w BMH2 suppressor of clathrin deficiency YER167w BCK2 suppressor of mutations in protein kinase C pathway components YFL031w HAC1 transcription factor YPL089c RLM1 transcription factor of the MADS box family YHR206w SKN7 transcription factor with similarity to HSF1P YHR084w STE12 transcriptional activator YIL147c SLN1 two-component signal transducer YLR006c SSK1 two-component signal transducer YJL128c PBS2 tyrosine protein kinase of the MAP kinase kinase family YDR069c DOA4 ubiquitin-specific protease YGL095c VPS45 vacuolar protein sorting-associated protein YGR136w weak similarity to chicken growth factor receptor-binding protein GRB2 homolog YER019w ISC1 weak similarity to human and mouse neutral sphingomyelinase YNL325c FIG4 weak similarity to inositol phosphatase YHL002w weak similarity to mammalian signal transducing adaptor YNL128w TEP1 weak similarity to tensin and to the mammalian tumor suppressor gene product MMAC1/PTEN/TEP1
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