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Saccharomyces cerevisiae - Functional Catalogue |
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nuclear organization (764 ORFs)
YOL038w PRE6 20S proteasome subunit (alpha4) YJL001w PRE3 20S proteasome subunit (beta1) YOR157c PUP1 20S proteasome subunit (beta2) YER094c PUP3 20S proteasome subunit (beta3) YPR103w PRE2 20S proteasome subunit (beta5) YOR362c PRE10 20S proteasome subunit C1 (alpha7) YER012w PRE1 20S proteasome subunit C11(beta4) YGR135w PRE9 20S proteasome subunit Y13 (alpha3) YML092c PRE8 20S proteasome subunit Y7 (alpha2) YGL011c SCL1 20S proteasome subunit YC7ALPHA/Y8 (alpha1) YGR253c PUP2 20S proteasome subunit(alpha5) YMR314w PRE5 20S proteasome subunit(alpha6) YBL041w PRE7 20S proteasome subunit(beta6) YFR050c PRE4 20S proteasome subunit(beta7) YDL007w RPT2 26S proteasome regulatory subunit YDR394w RPT3 26S proteasome regulatory subunit YER021w RPN3 26S proteasome regulatory subunit YFR004w RPN11 26S proteasome regulatory subunit YFR052w RPN12 26S proteasome regulatory subunit YGL048c RPT6 26S proteasome regulatory subunit YHR027c RPN1 26S proteasome regulatory subunit YHR200w RPN10 26S proteasome regulatory subunit YIL075c RPN2 26S proteasome regulatory subunit YKL145w RPT1 26S proteasome regulatory subunit YOR117w RPT5 26S proteasome regulatory subunit YOR259c RPT4 26S proteasome regulatory subunit YOR261c RPN8 26S proteasome regulatory subunit YDL020c RPN4 26S proteasome subunit YGR270w YTA7 26S proteasome subunit YHR069c RRP4 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOL021c DIS3 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YER142c MAG1 3-methyladenine DNA glycosylase YOR048c RAT1 5'-3' exoribonuclease YML060w OGG1 8-oxoguanine DNA glycosylase YBL074c AAR2 A1 cistron splicing factor YDL029w ARP2 actin-like protein YJL081c ARP4 actin-related protein YNL059c ARP5 Actin-related protein YNL220w ADE12 adenylosuccinate synthetase YDL226c GCS1 ADP-ribosylation factor GTPase-activating protein (ARF-GAP) YPR189w SKI3 antiviral protein YLR398c SKI2 antiviral protein and putative helicase YKL114c APN1 AP endonuclease YDR173c ARG82 arginine metabolism transcription factor YKL112w ABF1 ARS-binding factor YOR113w AZF1 asparagine-rich zinc finger protein YLR298c YHC1 associated with the U1 snRNP complex YER029c SMB1 associated with U1 snRNP as part of the Sm-core that is common to all spliceosomal snRNPs YGR013w SNU71 associated with U1 snRNP, no counterpart in mammalian U1 snRNP YJL092w HPR5 ATP-dependent DNA helicase YBR142w MAK5 ATP-dependent RNA helicase YOR204w DED1 ATP-dependent RNA helicase YPL119c DBP1 ATP-dependent RNA helicase YNL112w DBP2 ATP-dependent RNA helicase of DEAD box family YFL002c SPB4 ATP-dependent RNA helicase of DEAH box family YDR123c INO2 basic helix-loop-helix (BHLH) transcription factor YOL108c INO4 basic helix-loop-helix transcription factor YOR344c TYE7 basic helix-loop-helix transcription factor YOL067c RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YMR308c PSE1 beta karyopherin YGR229c SMI1 beta-1,3-glucan synthesis protein YBL103c RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YLR116w MSL5 branch point bridging protein YKL139w CTK1 carboxy-terminal domain (CTD) kinase, alpha subunit YJL006c CTK2 carboxy-terminal domain (CTD) kinase, beta subunit YML112w CTK3 carboxy-terminal domain (CTD) kinase, gamma subunit YPL204w HRR25 casein kinase I, ser/thr/tyr protein kinase YOR061w CKA2 casein kinase II alpha' chain YOR039w CKB2 casein kinase II beta' chain YGL019w CKB1 casein kinase II, beta subunit YIL035c CKA1 casein kinase II, catalytic alpha chain YER123w YCK3 casein kinase, isoform 3 YHL022c SPO11 catalytic subunit of the meiotic double strand break transesterase YLR318w EST2 catalytic subunit of the telomerase YBL021c HAP3 CCAAT-binding factor subunit YGL237c HAP2 CCAAT-binding factor subunit YKL109w HAP4 CCAAT-binding factor subunit YOR358w HAP5 CCAAT-binding factor subunit YJR122w CAF17 CCR4 associated factor YDR113c PDS1 cell cycle regulator YBR202w CDC47 cell division control protein YDL220c CDC13 cell division control protein YDR364c CDC40 cell division control protein YGL116w CDC20 cell division control protein YJL194w CDC6 cell division control protein YLR274w CDC46 cell division control protein YOL123w HRP1 CF Ib (RNA3' Cleavage factor Ib) YML102w CAC2 chromatin assembly complex, subunit p60 YKL108w SLD2 chromosomal DNA replication protein YDR254w CHL4 chromosome segregation protein YFL008w SMC1 chromosome segregation protein YFR031c SMC2 chromosome segregation protein YLR115w CFT2 cleavage and polyadenylation specificity factor, part of CF II YOR250c CLP1 cleavage/polyadenylation factor IA subunit YMR106c YKU80 component of DNA end-joining repair pathway YDR228c PCF11 component of pre-mRNA 3'-end processing factor CF I YGL044c RNA15 component of pre-mRNA 3'-end processing factor CF I YMR061w RNA14 component of pre-mRNA 3'-end processing factor CF I YJR093c FIP1 component of pre-mRNA polyadenylation factor PF I YLR277c YSH1 component of pre-mRNA polyadenylation factor PF I YPR056w TFB4 component of RNA polymerase transcription initiation TFIIH factor YNR023w SNF12 component of SWI/SNF global transcription activator complex YOR290c SNF2 component of SWI/SNF global transcription activator complex YPL016w SWI1 component of SWI/SNF global transcription activator complex YBR289w SNF5 component of SWI/SNF transcription activator complex YDR073w SNF11 component of SWI/SNF transcription activator complex YCR042c TSM1 component of TFIID complex YKL049c CSE4 component of the core centromere YPL022w RAD1 component of the nucleotide excision repairosome YJR002w MPP10 component of the U3 small nucleolar ribonucleoprotein YGL166w CUP2 copper-dependent transcription factor YNL167c SKO1 cre-binding bzip protein YOL001w PHO80 cyclin YPL042c SSN3 cyclin-dependent CTD kinase YJL157c FAR1 cyclin-dependent kinase inhibitor (CKI) YPL031c PHO85 cyclin-dependent protein kinase YDL108w KIN28 cyclin-dependent ser/thr protein kinase YML113w DAT1 datin, oligo(dA)/oligo(dT)-binding protein YOR386w PHR1 deoxyribodipyrimidine photo-lyase YER176w ECM32 DNA dependent ATPase/DNA helicase B YHR164c DNA2 DNA helicase YIL143c SSL2 DNA helicase YLR032w RAD5 DNA helicase YML061c PIF1 DNA helicase involved in mitochondrial DNA repair and telomere length YER171w RAD3 DNA helicase/ATPase YDL164c CDC9 DNA ligase YOR005c DNL4 DNA ligase IV YGL090w LIF1 DNA ligase IV interacting factor YCR092c MSH3 DNA mismatch repair protein YDR097c MSH6 DNA mismatch repair protein YMR167w MLH1 DNA mismatch repair protein YNL082w PMS1 DNA mismatch repair protein YOL090w MSH2 DNA mismatch repair protein YCR014c POL4 DNA polymerase YMR224c MRE11 DNA repair and meiotic recombination protein YJR035w RAD26 DNA repair and recombination protein YDR217c RAD9 DNA repair checkpoint protein YCR066w RAD18 DNA repair protein YDR004w RAD57 DNA repair protein YDR076w RAD55 DNA repair protein YDR369c XRS2 DNA repair protein YER095w RAD51 DNA repair protein YML095c RAD10 DNA repair protein YMR137c PSO2 DNA repair protein YNL250w RAD50 DNA repair protein YJL173c RFA3 DNA replication factor A, 13 KD subunit YNL312w RFA2 DNA replication factor A, 36 kDa subunit YAR007c RFA1 DNA replication factor A, 69 KD subunit YOL094c RFC4 DNA replication factor C, 37 kDa subunit YBR087w RFC5 DNA replication factor C, 40 KD subunit YNL290w RFC3 DNA replication factor C, 40 kDa subunit YJR068w RFC2 DNA replication factor C, 41 KD subunit YOR217w RFC1 DNA replication factor C, 95 KD subunit YOL006c TOP1 DNA topoisomerase I YNL088w TOP2 DNA topoisomerase II (ATP-hydrolysing) YLR234w TOP3 DNA topoisomerase III YNL216w RAP1 DNA-binding protein with repressor and activator activity YGL163c RAD54 DNA-dependent ATPase of the SNF2P family YKL144c RPC25 DNA-direcred RNA polymerase III, 25 KD subunit YKL045w PRI2 DNA-directed DNA polymerase alpha , 58 KD subunit (DNA primase) YIR008c PRI1 DNA-directed DNA polymerase alpha 48kDa subunit (DNA primase) YNL102w POL1 DNA-directed DNA polymerase alpha, 180 KD subunit YBL035c POL12 DNA-directed DNA polymerase alpha, 70 KD subunit YPR135w CTF4 DNA-directed DNA polymerase alpha-binding protein YJR006w HYS2 DNA-directed DNA polymerase delta, 55 KD subunit YDL102w CDC2 DNA-directed DNA polymerase delta, catalytic 125 KD subunit YFR023w PES4 DNA-directed DNA polymerase epsilon suppressor YNL262w POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YPR175w DPB2 DNA-directed DNA polymerase epsilon, subunit B YBR278w DPB3 DNA-directed DNA polymerase epsilon, subunit C YPL167c REV3 DNA-directed DNA polymerase zeta subunit YOR210w RPB10 DNA-directed polymerase I, II, III 8.3 subunit YNL248c RPA49 DNA-directed RNA polymerase A (I) chain, 46 kDa YJR063w RPA12 DNA-directed RNA polymerase I, 13.7 KD subunit YPR010c RPA135 DNA-directed RNA polymerase I, 135 KD subunit YOR341w RPA190 DNA-directed RNA polymerase I, 190 KD alpha subunit YOR340c RPA43 DNA-directed RNA polymerase I, 36 KD subunit YDR156w RPA14 DNA-directed RNA polymerase I, A14 subunit YOR224c RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YPR187w RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YBR154c RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YPR110c RPC40 DNA-directed RNA polymerase I, III 40 KD subunit YNL113w RPC19 DNA-directed RNA polymerase I,III 16 KD subunit YLR418c CDC73 DNA-directed RNA polymerase II accessory protein YNL025c SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YDR308c SRB7 DNA-directed RNA polymerase II holoenzyme and kornberg's mediator (SRB) subcomplex subunit YER022w SRB4 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YGR104c SRB5 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YHR041c SRB2 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL051w GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YCR081w SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR443c SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YLR071c RGR1 DNA-directed RNA polymerase II holoenzyme subunit YBR279w PAF1 DNA-directed RNA polymerase II regulator YOL005c RPB11 DNA-directed RNA polymerase II subunit, 13.6 kD YBR253w SRB6 DNA-directed RNA polymerase II suppressor protein YGL070c RPB9 DNA-directed RNA polymerase II, 14.2 KD subunit YOR151c RPB2 DNA-directed RNA polymerase II, 140 kDa chain YDR404c RPB7 DNA-directed RNA polymerase II, 19 KD subunit YDL140c RPO21 DNA-directed RNA polymerase II, 215 KD subunit YJL140w RPB4 DNA-directed RNA polymerase II, 32 kDa subunit YOR207c RET1 DNA-directed RNA polymerase III, 130 KD subunit YOR116c RPO31 DNA-directed RNA polymerase III, 160 KD subunit YNL151c RPC31 DNA-directed RNA polymerase III, 31 KD subunit YNR003c RPC34 DNA-directed RNA polymerase III, 34 KD subunit YDL150w RPC53 DNA-directed RNA polymerase III, 47 KD subunit YPR190c RPC82 DNA-directed RNA polymerase III, 82 KD subunit YHR143w-a RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YIL021w RPB3 DNA-directed RNA-polymerase II, 45 kDa YGL251c HFM1 DNA/RNA helicase YGL208w SIP2 dominant suppressor of some ts mutations in RPO21 and PRP4 YKL020c SPT23 dosage-dependent suppressor of Ty-induced promotor mutations YMR239c RNT1 double-stranded ribonuclease YKR054c DYN1 dynein heavy chain, cytosolic YDR390c UBA2 E1-like (ubiquitin-activating) enzyme YKL210w UBA1 E1-like (ubiquitin-activating) enzyme YDL064w UBC9 E2 ubiquitin-conjugating enzyme YDR054c CDC34 E2 ubiquitin-conjugating enzyme YER100w UBC6 E2 ubiquitin-conjugating enzyme YGL058w RAD6 E2 ubiquitin-conjugating enzyme YBR247c ENP1 effects N-glycosylation YPL046c ELC1 Elongin C transcription elongation factor YKR056w RNC1 endo-exonuclease YHR184w SSP1 essential for meiosis and spore formation YDR473c PRP3 essential splicing factor YOR319w HSH49 essential yeast splicing factor YOL012c HTZ1 evolutionarily conserved member of the histone H2A F/Z family of histone variants YER162c RAD4 excision repair protein YPL169c MEX67 factor for nuclear mRNA export YDL014w NOP1 fibrillarin YIL131c FKH1 forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle YER159c BUR6 functional homolog of human NC2alpha YDR397c NCB2 functional homolog of human NC2beta/Dr1 YPL037c EGD1 GAL4 DNA-binding enhancer protein YGL097w SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL207w SPT16 general chromatin factor YIL038c NOT3 general negative regulator of transcription, subunit 3 YBR112c CYC8 general repressor of transcription YCR084c TUP1 general transcription repressor YDR176w NGG1 general transcriptional adaptor or co-activator YDR392w SPT3 general transcriptional adaptor or co-activator YDR448w ADA2 general transcriptional adaptor or co-activator YNL236w SIN4 global regulator protein YHL025w SNF6 global transcription activator YNL199c GCR2 glycolytic genes transcriptional activator YLR293c GSP1 GTP-binding protein of the ras superfamily YOR185c GSP2 GTP-binding protein of the RAS superfamily YBR072w HSP26 heat shock protein YNL007c SIS1 heat shock protein YGL073w HSF1 heat shock transcription factor YPR065w ROX1 heme-dependent transcriptional repressor of hypoxic genes YGL253w HXK2 hexokinase II YDR006c SOK1 high copy suppressor of a cyclic AMP-dependent protein kinase mutant YMR284w YKU70 high-affinity DNA-binding protein YPR033c HTS1 histidine--tRNA ligase, mitochondrial YGR252w GCN5 histone acetyltransferase YPL001w HAT1 histone acetyltransferase subunit YNL021w HDA1 histone deacetylase A YNL330c RPD3 histone deacetylase B YPL127c HHO1 histone H1 protein YDR225w HTA1 histone H2A YBL003c HTA2 histone H2A.2 YDR224c HTB1 histone H2B YBL002w HTB2 histone H2B.2 YBR010w HHT1 histone H3 YNL031c HHT2 histone H3 YBR009c HHF1 histone H4 YNL030w HHF2 histone H4 YBL008w HIR1 histone transcription regulator YOR038c HIR2 histone transcription regulator YBR034c HMT1 hnRNP methyltransferase YDL106c PHO2 homeodomain protein YDL131w LYS21 homocitrate synthase YDL182w LYS20 homocitrate synthase YML027w YOX1 homoeodomain protein YNL068c FKH2 homology to D.melanogaster forkhead protein YDL227c HO homothallic switching endonuclease YDR138w HPR1 hyperrecombination protein related to TOP1P YGL238w CSE1 importin-beta-like protein YJL089w SIP4 interacts with SNF1 protein kinase YKL032c IXR1 intrastrand crosslink recognition protein and transcription factor YLL011w SOF1 involved in 18S pre-rRNA production YBR081c SPT7 involved in alteration of transcription start site selection YKR072c SIS2 involved in cell cycle-specific gene expression YKR063c LAS1 involved in cell morphogenesis, cytoskeletal regulation and bud formation YHR119w SET1 involved in chromatin-mediated gene regulation YGR099w TEL2 involved in controlling telomere length and position effect YPL177c CUP9 involved in copper homeostasis repression of protein import YER088c DOT6 involved in derepression of telomeric silencing YJL090c DPB11 involved in DNA replication and S-phase checkpoint YDR068w DOS2 involved in genome stability YDR021w FAL1 involved in maturation of 18S rRNA YGR158c MTR3 involved in mRNA transport YIL128w MET18 involved in NER repair and RNA polymerase II transcription YIL063c YRB2 involved in nuclear protein export YOR160w MTR10 involved in nuclear protein import YJL050w MTR4 involved in nucleocytoplasmic transport of mRNA YLR197w SIK1 involved in pre-rRNA processing YBR257w POP4 involved in processing of tRNAs and rRNAs YNL282w POP3 involved in processsing of tRNAs and rRNAs YMR001c CDC5 involved in regulation of DNA replication YNL251c NRD1 involved in regulation of nuclear pre-mRNA abundance YIL046w MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YGL201c MCM6 involved in replication YDL153c SAS10 involved in silencing YDR180w SCC2 involved in sister chromatid cohesion YPR057w BRR1 involved in snRNP biogenesis YGL120c PRP43 involved in spliceosome disassembly YDR082w STN1 involved in telomere length regulation YIR018w YAP5 involved in transcription activation YOL028c YAP7 involved in transcription activation YGL071w RCS1 iron-regulated transcriptional repressor YNL189w SRP1 karyopherin-alpha or importin YBL063w KIP1 kinesin-related protein YEL061c CIN8 kinesin-related protein YGL216w KIP3 kinesin-related protein required for nuclear migration YJR060w CBF1 kinetochore protein YGR140w CBF2 kinetochore protein complex CBF3, 110 KD subunit YDR328c SKP1 kinetochore protein complex CBF3, subunit D YMR168c CEP3 kinetochore protein complex, 71 KD subunit YMR094w CTF13 kinetochore protein complex, CBF3, 58 KD subunit YMR125w STO1 large subunit of the nuclear cap-binding protein complex CBC YKL149c DBR1 lariat-debranching enzyme YDR159w SAC3 leucine permease transcriptional regulator YBR182c SMP1 MADS-box transcription factor YNL016w PUB1 major polyadenylated RNA-binding protein of nucleus and cytoplasm YBR297w MAL33 maltose fermentation regulatory protein YGR288w MAL13 maltose pathway regulatory protein YDR480w DIG2 MAP kinase-associated protein, down-regulator of invasive growth and mating YPL049c DIG1 MAP kinase-associated protein, down-regulator of invasive growth and mating YHR066w SSF1 mating protein YCR039c MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040w MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCL066w HMLALPHA1 mating type regulatory protein, silenced copy at HML YCL067c HMLALPHA2 mating type regulatory protein, silenced copy at HML YCR096c A2 mating type regulatory protein, silenced copy at HMR locus YCR097w A1 mating type regulatory protein, silenced copy at HMR locus YIR033w MGA2 may be involved in the remodeling chromatin structure YGL025c PGD1 mediator complex subunit YMR112c MED11 mediator complex subunit YDL154w MSH5 meiosis-specific protein YER179w DMC1 meiosis-specific protein YFL003c MSH4 meiosis-specific protein YHR157w REC104 meiosis-specific protein YIL072w HOP1 meiosis-specific protein YLR263w RED1 meiosis-specific protein YAL009w SPO7 meiotic protein YJR021c REC107 meiotic recombination protein YLR329w REC102 meiotic recombination protein YMR133w REC114 meiotic recombination protein YNL210w MER1 meiotic recombination protein YHL027w RIM101 meiotic regulatory protein YOL135c MED7 member of RNA Polymerase II transcriptional regulation mediator complex YGR056w RSC1 member of RSC complex, which remodels the structure of chromatin YKR008w RSC4 member of RSC complex, which remodels the structure of chromatin YER047c SAP1 member of the AAA-protein family YPR019w CDC54 member of the CDC46P/MCM2P/MCM3P family YGL016w KAP122 Member of the karyopherin-beta family, nuclear import YGL241w KAP114 Member of the karyopherin-beta family, nuclear import YBL023c MCM2 member of the MCM2P,MCM3P,CDC46P family YOL148c SPT20 member of the TBP class of SPT proteins that alter transcription site selection YMR021c MAC1 metal binding activator YJL056c ZAP1 metalloregulatory protein involved in zinc-responsive transcriptional regulation YLR131c ACE2 metallothionein expression activator YOR058c ASE1 microtubule-associated protein (nonmotor) YBR026c (MRF1) mitochondrial respiratory function protein YDL003w MCD1 Mitotic Chromosome Determinant YBR236c ABD1 mRNA cap methyltransferase YGL130w CEG1 mRNA guanylyltransferase (mRNA capping enzyme, alpha subunit) YER165w PAB1 mRNA polyadenylate-binding protein YKL186c MTR2 mRNA transport protein YER161c SPT2 multifunctional HMG-like chromatin protein YJL130c URA2 multifunctional pyrimidine biosynthesis protein YKR095w MLP1 myosin-like protein related to USO1P YML051w GAL80 negative regulator for expression of galactose-induced genes YKL185w ASH1 negative regulator of HO transcription YPL139c UME1 negative regulator of meiosis YHL020c OPI1 negative regulator of phospholipid biosynthesis pathway YGL151w NUT1 negative transcription regulator from artifical reporters YPR168w NUT2 negative transcription regulator from artifical reporters YDR207c UME6 negative transcriptional regulator YDR174w HMO1 Non-histone protein YLL036c PRP19 non-snRNP sliceosome component required for DNA repair YJL148w RPA34 nonessential component of RNA-polI YBR089c-a NHP6B nonhistone chromosomal protein YPR052c NHP6A nonhistone chromosomal protein related to mammalian HMG1 YGR072w UPF3 nonsense-mediated mRNA decay protein YBL020w RFT1 nuclear division protein YJR112w NNF1 nuclear envelope protein YML031w NDC1 nuclear envelope protein YGR218w CRM1 nuclear export factor, exportin YCL029c BIK1 nuclear fusion protein YGR159c NSR1 nuclear localization sequence binding protein YGL122c NAB2 nuclear poly(A)-binding protein YMR129w POM152 nuclear pore membrane glycoprotein YBL079w NUP170 nuclear pore protein YDL116w NUP84 nuclear pore protein YDR192c NUP42 nuclear pore protein YER105c NUP157 nuclear pore protein YFR002w NIC96 nuclear pore protein YGL092w NUP145 nuclear pore protein YGL100w SEH1 nuclear pore protein YGL172w NUP49 nuclear pore protein YGR119c NUP57 nuclear pore protein YIL115c NUP159 nuclear pore protein YJL041w NSP1 nuclear pore protein YJL061w NUP82 nuclear pore protein YJR042w NUP85 nuclear pore protein YKL057c NUP120 nuclear pore protein YKL068w NUP100 nuclear pore protein YKR082w NUP133 nuclear pore protein YLR335w NUP2 nuclear pore protein YML103c NUP188 nuclear pore protein YMR047c NUP116 nuclear pore protein YOR098c NUP1 nuclear pore protein YCR093w CDC39 nuclear protein YGL115w SNF4 nuclear regulatory protein YBR167c POP7 nuclear RNase P subunit YER009w NTF2 nuclear transport factor YAL025c MAK16 nuclear viral propagation protein YCR018c SRD1 nucleolar protein YDR432w NPL3 nucleolar protein YNL061w NOP2 nucleolar protein YPL043w NOP4 nucleolar protein YDL208w NHP2 nucleolar rRNA processing protein YHR072w-a NOP10 nucleolar rRNA processing protein YHR089c GAR1 nucleolar rRNA processing protein YJL039c NUP192 nucleoporin localize at the inner site of the nuclear membrane YKR048c NAP1 nucleosome assembly protein I YBR114w RAD16 nucleotide excision repair protein YJR052w RAD7 nucleotide excision repair protein YMR201c RAD14 nucleotide excision repair protein YEL037c RAD23 nucleotide excision repair protein (ubiquitin-like protein) YGL091c NBP35 nucleotide-binding protein YDL200c MGT1 O6-methylguanine DNA repair methyltransferase YML065w ORC1 origin recognition complex, 104 KD subunit YHR118c ORC6 origin recognition complex, 50 KD subunit YNL261w ORC5 origin recognition complex, 50 kDa subunit YPR162c ORC4 origin recognition complex, 56 KD subunit YLL004w ORC3 origin recognition complex, 62 kDa subunit YBR060c ORC2 origin recognition complex, 72 kDa subunit YGR178c PBP1 PAB1P interacting protein YHR195w NVJ1 part of nucleus-vacuole junctions YAL051w OAF1 peroxisome proliferating transcription factor YOR363c PIP2 peroxisome proliferating transcription factor YNL267w PIK1 phosphatidylinositol 4-kinase YBL005w PDR3 pleiotropic drug resistance regulatory protein YKR002w PAP1 poly(A) polymerase YPL190c NAB3 polyadenylated RNA-binding protein YJL025w RRN7 polymerase I specific transcription initiation factor YJR043c POL32 polymerase-associated gene, third (55 kDa) subunit of DNA polymerase delta YKL015w PUT3 positive activator of the proline utilisation pathway YLR430w SEN1 positive effector of tRNA-splicing endonuclease YGL192w IME4 positive transcription factor for IME2 YGR232w NAS6 possible homolog of human 26S proteasome regulatory subunit p28 YCL011c GBP2 potential telomere-associated protein YDR301w CFT1 pre-mRNA 3'-end processing factor CF II YBR237w PRP5 pre-mRNA processing RNA-helicase YDL043c PRP11 pre-mRNA splicing factor YER013w PRP22 pre-mRNA splicing factor YGR075c PRP38 pre-mRNA splicing factor YJL203w PRP21 pre-mRNA splicing factor YKL074c MUD2 pre-mRNA splicing factor YML046w PRP39 pre-mRNA splicing factor YMR268c PRP24 pre-mRNA splicing factor YDL030w PRP9 pre-mRNA splicing factor (snRNA-associated protein) YDR088c SLU7 pre-mRNA splicing factor affecting 3' splice site choice YDR243c PRP28 pre-mRNA splicing factor RNA helicase of DEAD box family YGR091w PRP31 pre-mRNA splicing protein YLR223c IFH1 pre-rRNA processing machinery control protein YKL205w LOS1 pre-tRNA splicing protein YDR463w STP1 pre-tRNA splicing protein, transcription factor YMR229c RRP5 processing of pre-ribosomal RNA YBR088c POL30 Proliferating Cell Nuclear Antigen (PCNA) YML074c NPI46 proline cis-trans isomerase YBR173c UMP1 proteasome maturation factor YNL221c POP1 protein component of ribonuclease P and ribonuclease MRP YDL017w CDC7 protein kinase YDL101c DUN1 protein kinase YPL008w CHL1 protein of the DEAH box family YML069w POB3 protein that binds to DNA polymerase I (PolI) YFL001w DEG1 pseudouridine synthase YNL292w PUS4 pseudouridine synthase YPL212c PUS1 pseudouridine synthase 1 YBR186w PCH2 putative ATPase YDR395w SXM1 putative beta-karyopherin YMR128w ECM16 putative DEAH-box RNA helicase YDL160c DHH1 putative RNA helicase of the DEAD box family YGL078c DBP3 putative RNA helicase required for pre-rRNA processing YLR175w CBF5 putative rRNA pseuduridine synthase YBL066c SEF1 putative transcription factor YER110c KAP123 RAN-binding protein YBR275c RIF1 RAP1-interacting factor 1 YLR453c RIF2 RAP1P interacting factor 2 YDL059c RAD59 recombination and DNA repair protein YML032c RAD52 recombination and DNA repair protein YGL244w RTF1 regulates DNA binding properties of TBP YKL038w RGT1 regulator of glucose-induced genes YBR240c THI2 regulator of the thiamine biosynthetic genes YDR257c RMS1 regulatory protein YMR016c SOK2 regulatory protein in the PKA signal transduction pathway YCL055w KAR4 regulatory protein required for pheromone induction of karyogamy genes YDR052c DBF4 regulatory subunit for CDC7P protein kinase YDR028c REG1 regulatory subunit for protein phosphatase GLC7P YKL193c SDS22 regulatory subunit for the mitotic function of type I protein phosphatase YEL032w MCM3 replication initiation protein YLR176c RFX1 repressor of DNA damage-inducible genes YMR078c CTF18 required for accurate chromosome transmission in mitosis and maintenance of normal telomere length YER109c FLO8 required for diploid filamentous growth YPL211w NIP7 required for efficient 60S ribosome subunit biogenesis YNR052c POP2 required for glucose derepression YJL080c SCP160 required for maintenance of exact ploidy YHR065c RRP3 required for maturation of the 35S primary transcript YLR103c CDC45 required for minichromosome maintenance and initiation of chromosomal DNA replication YKL089w MIF2 required for normal chromosome segregation and spindle integrity YMR179w SPT21 required for normal transcription at a number of loci YHR004c NEM1 required for nuclear morphology YER107c GLE2 required for nuclear pore complex structure and function YGL033w HOP2 required for pairing of homologous chromosomes YOR310c NOP58 required for pre-18S rRNA processing YHR062c RPP1 required for processing of tRNA and 35S rRNA YAL033w POP5 required for processing of tRNAs and rRNAs YBL018c POP8 required for processing of tRNAs and rRNAs YGR030c POP6 required for processing of tRNAs and rRNAs YCL054w SPB1 required for ribosome synthesis, putative methylase YIL150c DNA43 required for S-phase initiation or completion YGR098c ESP1 required for sister chromatid separation YGR180c RNR4 ribonucleotide reductase small subunit YDR195w REF2 RNA 3'-end formation protein YDR381w YRA1 RNA annealing protein YDL207w GLE1 RNA export mediator YLL008w DRS1 RNA helicase of the DEAD box family YNR038w DBP6 RNA helicase required for 60S ribosomal subunit assembly YER172c BRR2 RNA helicase-related protein YKL125w RRN3 RNA polymerase I specific transcription factor YBL014c RRN6 RNA polymerase I specific transcription initiation factor YLR141w RRN5 RNA polymerase I specific transcription initiation factor YML043c RRN11 RNA polymerase I specific transcription initiation factor YMR270c RRN9 RNA polymerase I specific transcription initiation factor YBL025w RRN10 RNA polymerase I-specific transcription initiation factor YHR058c MED6 RNA polymerase II transcriptional regulation mediator YKR086w PRP16 RNA-dependent ATPase YNR011c PRP2 RNA-dependent ATPase of DEAH box family YIR015w RPR2 RNase P subunit YPL266w DIM1 rRNA (adenine-N6,N6-)-dimethyltransferase YDR190c RVB1 RUVB-like protein YGR188c BUB1 ser/thr protein kinase YHR082c KSP1 ser/thr protein kinase YMR139w RIM11 ser/thr protein kinase YOR351c MEK1 ser/thr protein kinase YGR040w KSS1 ser/thr protein kinase of the MAP kinase family YKL101w HSL1 ser/thr protein kinase, coupling septin ring assembly to cell cycle progression YPL153c RAD53 ser/thr/tyr protein kinase YDR227w SIR4 silencing regulatory and DNA-repair protein YLR442c SIR3 silencing regulatory and DNA-repair protein YKR101w SIR1 silencing regulatory protein YDL042c SIR2 silencing regulatory protein and DNA-repair protein YPR045c similarity to C.elegans hypothetical protein YPR133c similarity to C.elegans hypothetical protein YKL095w YJU2 similarity to C.elegans hypothetical proteins YAL019w FUN30 similarity to helicases of the SNF2/RAD54 family YOL133w HRT1 similarity to Lotus RING-finger protein YER184c similarity to multidrug resistance proteins PDR3P and PDR1P YNL206c RTT106 similarity to structure-specific recognition proteins YCR106w similarity to transcription factor YJL103c similarity to YBR239c YHL034c SBP1 single-strand nucleic acid binding protein YBR103w SIF2 SIR4P interacting protein YBL026w LSM2 Sm-like (Lsm) protein YER112w LSM4 Sm-like (Lsm) protein YER146w LSM5 Sm-like (Lsm) protein YLR438c-a LSM3 Sm-like (Lsm) protein YNL147w LSM7 Sm-like (Lsm) protein YPL178w CBC2 small subunit of the nuclear cap-binding protein complex CBC YGR074w SMD1 snRNA-associated protein YPR182w SMX3 snRNA-associated protein of the SM family YFL017w-a SMX2 snRNP G protein (the homologue of the human Sm-G) YBR055c PRP6 snRNP(U4/U6)-associated splicing factor YGL086w MAD1 spindle assembly checkpoint protein YNL126w SPC98 spindle pole body component YJL013c MAD3 spindle-assembly checkpoint protein YOR159c SME1 spliceosomal snRNA-associated Sm core protein required for mRNA splicing, also likely associated with telomerase TLC1 RNA YLR147c SMD3 spliceosomal snRNA-associated Sm core protein required for pre-mRNA splicing YJR022w LSM8 splicing factor YKL012w PRP40 splicing factor YPR101w SNT309 splicing factor YLR399c BDF1 sporulation protein YNL204c SPS18 sporulation-specific zinc-finger protein YKL113c RAD27 ssDNA endonuclease and 5'-3'exonuclease YMR037c MSN2 stress responsive regulatory protein YCL059c KRR1 strong similarity to fission yeast rev interacting protein mis3 YPR196w strong similarity to regulatory protein Mal63p YCR072c strong similarity to S. pombe trp-asp repeat containing protein YGR258c RAD2 structure-specific nuclease of the nucleotide excision repairosome YBL084c CDC27 subunit of anaphase-promoting complex (cyclosome) YFR036w CDC26 subunit of anaphase-promoting complex (cyclosome) YHR166c CDC23 subunit of anaphase-promoting complex (cyclosome) YKL022c CDC16 subunit of anaphase-promoting complex (cyclosome) YNL172w APC1 subunit of anaphase-promoting complex (cyclosome) YNR010w CSE2 subunit of RNA polymerase II mediator complex YDL008w APC11 subunit of the anaphase promoting complex YDR118w APC4 subunit of the anaphase promoting complex YDL097c RPN6 subunit of the regulatory particle of the proteasome YDL147w RPN5 subunit of the regulatory particle of the proteasome YDR427w RPN9 subunit of the regulatory particle of the proteasome YPR108w RPN7 subunit of the regulatory particle of the proteasome YCR052w RSC6 subunit of the RSC complex YFR037c RSC8 subunit of the RSC complex YIL126w STH1 subunit of the RSC complex YLR321c SFH1 subunit of the RSC complex YOR213c SAS5 subunit of the RSC complex YGL254w FZF1 sulfite resistance protein YNL222w SSU72 suppressor of cs mutant of SUA7 YKR092c SRP40 suppressor of mutant AC40 of RNA polymerase I and III YBR152w SPP381 Suppressor of Pre-mRNA Processing mutant YDR310c SUM1 suppressor of SIR mutations YDR285w ZIP1 synaptonemal complex protein YLR233c EST1 telomere elongation protein YPL128c TBF1 telomere TTAGGG repeat-binding factor 1 YKL058w TOA2 TFIIA subunit (transcription initiation factor), 13.5 kD YOR194c TOA1 TFIIA subunit (transcription initiation factor), 32 kD YPR086w SUA7 TFIIB subunit (transcription initiation factor), factor E YBR198c TAF90 TFIID and SAGA subunit YDR167w TAF25 TFIID and SAGA subunit YGL112c TAF60 TFIID and SAGA subunit YMR236w TAF17 TFIID and SAGA subunit YGR274c TAF145 TFIID subunit (TBP-associated factor), 145 kD YML098w TAF19 TFIID subunit (TBP-associated factor), 19 kD YML015c TAF40 TFIID subunit (TBP-associated factor), 40KD YMR227c TAF67 TFIID subunit (TBP-associated factor), 67 kD YKR062w TFA2 TFIIE subunit (transcription initiation factor), 43 KD YKL028w TFA1 TFIIE subunit (transcription initiation factor), 66 kD YMR277w FCP1 TFIIF interacting component of CTD phosphatase YGR186w TFG1 TFIIF subunit (transcription initiation factor), 105 kD YPL129w ANC1 TFIIF subunit (transcription initiation factor), 30 kD YGR005c TFG2 TFIIF subunit (transcription initiation factor), 54 kD YDR311w TFB1 TFIIH subunit (transcription initiation factor), 75 kD YPR025c CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPL122c TFB2 TFIIH subunit (transcription/repair factor) YPR186c PZF1 TFIIIA (transcription initiation factor) YGR246c BRF1 TFIIIB subunit, 70 kD YNL039w TFC5 TFIIIB subunit, 90 kD YGR047c TFC4 TFIIIC (transcription initiation factor) subunit, 131 kD YAL001c TFC3 TFIIIC (transcription initiation factor) subunit, 138 kD YOR110w TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YDR362c TFC6 TFIIIC (transcription initiation factor) subunit, 91 kD YBR123c TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YGL043w DST1 TFIIS (transcription elongation factor) YER148w SPT15 the TATA-binding protein TBP YOR074c CDC21 thymidylate synthase YOL115w TRF4 topoisomerase I-related protein YGR063c SPT4 transcription elongation protein YGR116w SPT6 transcription elongation protein YML010w SPT5 transcription elongation protein YBL093c ROX3 transcription factor YBR049c REB1 transcription factor YCR065w HCM1 transcription factor YDL165w CDC36 transcription factor YDR146c SWI5 transcription factor YER111c SWI4 transcription factor YFL031w HAC1 transcription factor YFR034c PHO4 transcription factor YGL013c PDR1 transcription factor YKL043w PHD1 transcription factor YKR099w BAS1 transcription factor YLR098c CHA4 transcription factor YLR182w SWI6 transcription factor YLR256w HAP1 transcription factor YLR451w LEU3 transcription factor YOR140w SFL1 transcription factor YOR162c YRR1 transcription factor YPL248c GAL4 transcription factor YFL021w GAT1 transcription factor for nitrogen regulation YER040w GLN3 transcription factor for positive nitrogen regulation YML099c ARG81 transcription factor involved in arginine metabolism YMR042w ARG80 transcription factor involved in arginine metabolism YMR280c CAT8 transcription factor involved in gluconeogenesis YGL181w GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YMR043w MCM1 transcription factor of the MADS box family YPL089c RLM1 transcription factor of the MADS box family YLR014c PPR1 transcription factor regulating pyrimidine pathway YJR094c IME1 transcription factor required for sporulation YHR206w SKN7 transcription factor with similarity to HSF1P YDR259c YAP6 transcription factor, of a fungal-specific family of bzip proteins YHL009c YAP3 transcription factor, of a fungal-specific family of bzip proteins YDL056w MBP1 transcription factor, subunit of the MBF factor YOR174w MED4 transcription regulation mediator YJL127c SPT10 transcription regulatory protein YJL176c SWI3 transcription regulatory protein YOL004w SIN3 transcription regulatory protein YPL082c MOT1 transcriptional accessory protein YDR423c CAD1 transcriptional activator YHR084w STE12 transcriptional activator YKL062w MSN4 transcriptional activator YOL116w MSN1 transcriptional activator YOR028c CIN5 transcriptional activator YPL075w GCR1 transcriptional activator YIR023w DAL81 transcriptional activator for allantoin and GABA catabolic genes YNL314w DAL82 transcriptional activator for allantoin catabolic genes YDL170w UGA3 transcriptional activator for GABA catabolic genes YML007w YAP1 transcriptional activator involved in oxidative stress response YEL009c GCN4 transcriptional activator of amino acid biosynthetic genes YOL089c HAL9 transcriptional activator of ENA1 YDR034c LYS14 transcriptional activator of lysine pathway genes YIL129c TAO3 Transcriptional Activator of OCH1 YIR017c MET28 transcriptional activator of sulfur amino acid metabolism YNL103w MET4 transcriptional activator of sulfur metabolism YPR104c FHL1 transcriptional activator of the forkhead/hnf3 family YLR055c SPT8 transcriptional adaptor or co-activator YMR039c SUB1 transcriptional coactivator YPL254w HFI1 transcriptional coactivator YOR229w WTM2 transcriptional modulator YOR230w WTM1 transcriptional modulator YBR193c MED8 transcriptional regulation mediator YDL005c MED2 transcriptional regulation mediator YAL021c CCR4 transcriptional regulator YIL084c SDS3 transcriptional regulator YNL012w SPO1 transcriptional regulator involved in sporulation YER068w MOT2 transcriptional repressor YGL035c MIG1 transcriptional repressor YJL110c GZF3 transcriptional repressor YKR034w DAL80 transcriptional repressor for allantoin and GABA catabolic genes YMR182c RGM1 transcriptional repressor protein YBL024w NCL1 tRNA (cytosine-5-)-methyltransferase YOR274w MOD5 tRNA isopentenyltransferase YJL087c TRL1 tRNA ligase YER168c CCA1 tRNA nucleotidyltransferase YPL083c SEN54 tRNA splicing endonuclease alpha subunit YLR105c SEN2 tRNA splicing endonuclease beta subunit YMR059w SEN15 tRNA splicing endonuclease delta subunit YAR008w SEN34 tRNA splicing endonuclease gamma subunit YBR083w TEC1 Ty transcription activator YOR337w TEA1 TY1 enhancer activator YIL061c SNP1 U1 small nuclear ribonucleoprotein YDR240c SNU56 U1 snRNA protein, no counterpart in mammalian snRNP YDR235w PRP42 U1 snRNP associated protein, required for pre-mRNA splicing YLR275w SMD2 U1 snRNP protein of the Sm class YBR119w MUD1 U1 snRNP-specific A protein YMR240c CUS1 U2 snRNP protein YPR178w PRP4 U4/U6 snRNP 52 KD protein YGR006w PRP18 U5 snRNA-associated protein YHR165c PRP8 U5 snRNP protein, pre-mRNA splicing factor YLL039c UBI4 ubiquitin YMR276w DSK2 ubiquitin-like protein YDR069c DOA4 ubiquitin-specific protease YML021c UNG1 uracil-DNA glycosylase YKL024c URA6 uridine-monophosphate kinase YGR136w weak similarity to chicken growth factor receptor-binding protein GRB2 homolog YML076c weak similarity to transcription factor YBR239c weak similarity to transcription factor PUT3P YER045c ACA1 weak similarity to transcription factor SKO1P YBR150c TBS1 weak similarity to transcription factors YKR064w weak similarity to transcription factors YLR266c weak similarity to transcription factors YPL133c weak similarity to transcription factors YKL222c weak similarity to transcription factors, similarity to finger proteins YOR162c, YOR172w and YLR266c YBL054w weak similarity to transforming protein (B-myb) YMR019w STB4 weak similarity to YIL130w, PUT3P and other transcription factors YKL005c weak similarity to YKR029c and D.melanogaster transcription elongation factor DmS-II YER122c GLO3 zinc finger protein YLR403w SFP1 zinc finger protein YDR216w ADR1 zinc-finger transcription factor YGR044c RME1 zinc-finger transcription factor YGR285c ZUO1 zuotin, a putative Z-DNA binding protein
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