Workshop on Bioinformatics for Medical and Pharmaceutical Research
November 16-17, 2009


The importance of bioinformatics is growing fast in medical and pharmaceutical research in order to analyze various types of chemical and genomic data. For example, these data may include sequenced genomes of a variety of organisms, gene expression data, protein expression data, protein 3D structural data, protein interactions, gene ontology, molecular pathways, chemical structures, genetic variation data (such as CNV and SNP), and an enormous amount of textual data in the literature. We are faced with the necessity of developping novel databases and algorithms that enable us to analyze these growing resources in order to understand cancer mechanism or develop new drugs, for example. The goal of this workshop is to present recent bioinformatics technologies which are useful for medical and pharmaceutical research. We invited several speakers from the biology/bioinformatics community who will present current research problems in bioinformatics for medical and pharmaceutical research. This workshop is supported by Institut Curie, Inserm, Mines ParisTech, Kyoto University Bioinformatics Center, and JSPS.



BDD Salle Annexe 1&2&3 or Amphitheatre de la BDD
Institut Curie - Centre de Recherche Biologie du Developpement
26 rue d'Ulm, 75248 Paris cedex 05, France


Monday, Nov 16, 2009

10:00-10:10 Opening Welcome

10:10-11:00 Minoru Kanehisa (Kyoto University)
                  "KEGG for representation and analysis of molecular networks involving diseases and drugs"

11:00-11:50 Jean-Philippe Vert (Institut Curie / Inserm U900 / Mines ParisTech)
                  "Machine learning in bioinformatics and drug discovery"

11:50-14:00 Lunch

14:00-14:50 Philippe Hupe (Institut Curie / Inserm U900 / Mines ParisTech)
                  "Data integration for cancer research"

14:50-15:40 Yoshihiro Yamanishi (Institut Curie / Inserm U900 / Mines ParisTech)
                  "Prediction of drug-target interactions from chemical, genomic and pharmacological data"

15:40-16:00 Break

16:00-16:30 Ai Muto (Kyoto University)
                  "Structural similarity-based approach to characterize crude drug components"

16:30-17:00 Brice Hoffmann (Institut Curie / Inserm U900 / Mines ParisTech)
                  "An in silico chemogenomics approach to virtual screening of GPCR"

17:00-17:30 Takeyuki Tamura (Kyoto University)
                  "Finding minimum reaction cuts of metabolic networks under a boolean model"

17:30-18:00 Fantine Mordelet (Institut Curie / Inserm U900 / Mines ParisTech)
                  "SIRENE : supervised inference of regulatory networks"

18:00 Close

Tuesday, Nov 17, 2009

10:00-10:50 Susumu Goto (Kyoto University)
                  "An application of network analyses to cardiovascular disease"

10:50-11:40 Andrei Zinovyev (Institut Curie / Inserm U900 / Mines ParisTech)
                  "Asymptotology of biochemical networks for NFkB pathway modeling"

11:40 Close