iced.normalization.estimate_block_biases¶

iced.normalization.estimate_block_biases(counts, lengths, cnv, verbose=False)¶

Estimates block biases

Parameters:	counts : ndarray or sparse arrays (n, n) lengths : ndarray (L, ) number of bins associated to each chromosomes. cnv : ndarray (n, ) copy number associated to each bin. Only breakpoints are useful
Returns:	block_biases : ndarray or sparse array (n, n) The estimated block biases